• 33480 引文
  • 87 h-指數
1975 …2018
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研究成果 1975 2018

1987
29 引文 (Scopus)

Regulation of DNA topoisomerases during cellular differentiation

Bodley, A. L., Wu, H. Y. & Liu, L-F., 1987, NCI Monographs. 4 編輯 p. 31-35 5 p.

研究成果: 書貢獻/報告類型章節

Experimental Leukemias
DNA Topoisomerases
Type II DNA Topoisomerase
Leukemia, Erythroblastic, Acute
Type I DNA Topoisomerase
229 引文 (Scopus)

Roles of DNA topoisomerases in simian virus 40 DNA replication in vitro

Yang, L., Wold, M. S., Li, J. J., Kelly, T. J. & Liu, L-F., 1987, 於 : Proceedings of the National Academy of Sciences of the United States of America. 84, 4, p. 950-954 5 p.

研究成果: 雜誌貢獻文章

DNA Topoisomerases
Type II DNA Topoisomerase
Simian virus 40
DNA Replication
Type I DNA Topoisomerase
1332 引文 (Scopus)

Supercoiling of the DNA template during transcription.

Liu, L-F. & Wang, J. C., 十月 1987, 於 : Proceedings of the National Academy of Sciences of the United States of America. 84, 20, p. 7024-7027 4 p.

研究成果: 雜誌貢獻文章

DNA
DNA Gyrase
Type I DNA Topoisomerase
Type II DNA Topoisomerase
DNA-Directed RNA Polymerases
1986
27 引文 (Scopus)

Chapter 24. DNA Topoisomerases as Therapeutic Targets in Cancer Chemotherapy

Chen, G. L. & Liu, L-F., 1986, 於 : Annual Reports in Medicinal Chemistry. 21, C, p. 257-262 6 p.

研究成果: 雜誌貢獻文章

DNA Topoisomerases
Chemotherapy
DNA
Type II DNA Topoisomerase
Type I DNA Topoisomerase
235 引文 (Scopus)

DNA damage by antitumor acridines mediated by mammalian DNA topoisomerase II

Rowe, T. C., Chen, G. L., Hsiang, Y. H. & Liu, L-F., 1986, 於 : Cancer Research. 46, 4 II, p. 2021-2026 6 p.

研究成果: 雜誌貢獻文章

Acridines
Type II DNA Topoisomerase
DNA Damage
DNA Breaks
Amsacrine
37 引文 (Scopus)

Induction of sister chromatid exchanges by inhibitors of topoisomerases

Lim, M., Liu, L-F., Jacobson-Kram, D. & Williams, J. R., 十二月 1986, 於 : Cell Biology and Toxicology. 2, 4, p. 485-494 10 p.

研究成果: 雜誌貢獻文章

Topoisomerase Inhibitors
Sister Chromatid Exchange
Topoisomerase I Inhibitors
Topoisomerase II Inhibitors
Type II DNA Topoisomerase
74 引文 (Scopus)

In vivo localization of DNA topoisomerase II cleavage sites on Drosophila heat shock chromatin

Rowe, T. C., Wang, J. C. & Liu, L-F., 1986, 於 : Molecular and Cellular Biology. 6, 4, p. 985-992 8 p.

研究成果: 雜誌貢獻文章

Teniposide
Nucleic Acid Hybridization
Type II DNA Topoisomerase
DNA Restriction Enzymes
Heat-Shock Proteins
151 引文 (Scopus)

Newly replicated DNA is associated with DNA topoisomerase II in cultured rat prostatic adenocarcinoma cells

Nelson, W. G., Liu, L-F. & Coffey, D. S., 1986, 於 : Nature. 322, 6075, p. 187-189 3 p.

研究成果: 雜誌貢獻文章

Teniposide
Type II DNA Topoisomerase
Adenocarcinoma
DNA
DNA Replication
1985
2031 引文 (Scopus)

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I

Hsiang, Y. H., Hertzberg, R., Hecht, S. & Liu, L-F., 1985, 於 : Journal of Biological Chemistry. 260, 27, p. 14873-14878 6 p.

研究成果: 雜誌貢獻文章

Camptothecin
Biological Models
Type II DNA Topoisomerase
Type I DNA Topoisomerase
DNA Breaks
111 引文 (Scopus)

In vivo mapping of DNA topoisomerase II-specific cleavage sites on SV40 chromatin

Yang, L., Rowe, T. C., Nelson, E. M. & Liu, L-F., 1985, 於 : Cell. 41, 1, p. 127-132 6 p.

研究成果: 雜誌貢獻文章

Type II DNA Topoisomerase
Chromatin
Amsacrine
Reunion
Simian virus 40
195 引文 (Scopus)

Purification and characterization of a type II DNA topoisomerase from bovine calf thymus

Halligan, B. D., Edwards, K. A. & Liu, L-F., 1985, 於 : Journal of Biological Chemistry. 260, 4, p. 2475-2482 8 p.

研究成果: 雜誌貢獻文章

Thymus
Type II DNA Topoisomerase
Thymus Gland
Purification
Adenosine Triphosphate
568 引文 (Scopus)

Topoisomerase II is a structural component of mitotic chromosome scaffolds

Earnshaw, W. C., Halligan, B., Cooke, C. A., Heck, M. M. S. & Liu, L-F., 五月 1 1985, 於 : Journal of Cell Biology. 100, 5, p. 1706-1715 10 p.

研究成果: 雜誌貢獻文章

Type II DNA Topoisomerase
Chromosomes
Interphase
Anti-Idiotypic Antibodies
Peptides
1984
1158 引文 (Scopus)

Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II

Tewey, K. M., Rowe, T. C., Yang, L., Halligan, B. D. & Liu, L-F., 1984, 於 : Science. 226, 4673, p. 466-468 3 p.

研究成果: 雜誌貢獻文章

Type II DNA Topoisomerase
Doxorubicin
DNA Damage
Antineoplastic Agents
Teniposide
67 引文 (Scopus)

Identification of the breakage-reunion subunit of T4 DNA topoisomerase

Rowe, T. C., Tewey, K. M. & Liu, L-F., 1984, 於 : Journal of Biological Chemistry. 259, 14, p. 9177-9181 5 p.

研究成果: 雜誌貢獻文章

Reunion
Type I DNA Topoisomerase
DNA
Proteins
Paper Electrophoresis
507 引文 (Scopus)

Intercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II

Tewey, K. M., Chen, G. L., Nelson, E. M. & Liu, L-F., 1984, 於 : Journal of Biological Chemistry. 259, 14, p. 9182-9187 6 p.

研究成果: 雜誌貢獻文章

Reunion
Type II DNA Topoisomerase
ellipticine
Antineoplastic Agents
DNA
576 引文 (Scopus)

Mechanism of antitumor drug action: Poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide

Nelson, E. M., Tewey, K. M. & Liu, L-F., 1984, ISOTOPENPRAXIS. 1 編輯 卷 20. p. 1361-1365 5 p.

研究成果: 書貢獻/報告類型章節

Type II DNA Topoisomerase
Amsacrine
Antineoplastic Agents
Poisoning
DNA Breaks
618 引文 (Scopus)

Nonintercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II

Chen, G. L., Yang, L., Rowe, T. C., Halligan, B. D., Tewey, K. M. & Liu, L-F., 1984, 於 : Journal of Biological Chemistry. 259, 21, p. 13560-13566 7 p.

研究成果: 雜誌貢獻文章

Reunion
Type II DNA Topoisomerase
Podophyllotoxin
Antineoplastic Agents
DNA
437 引文 (Scopus)

Role of Topoisomerase II in Mediating Epipodophyllotoxin-induced DNA Cleavage

Ross, W., Glisson, B., Yalowich, J., Rowe, T. & Liu, L-F., 十二月 1 1984, 於 : Cancer Research. 44, p. 5857-5860 4 p.

研究成果: 雜誌貢獻文章

Podophyllotoxin
Type II DNA Topoisomerase
DNA Cleavage
Teniposide
Etoposide
1983
50 引文 (Scopus)

Association of eukaryotic DNA topoisomerase I with nucleosomes and chromosomal proteins

Javaherian, K. & Liu, L-F., 一月 25 1983, 於 : Nucleic Acids Research. 11, 2, p. 461-472 12 p.

研究成果: 雜誌貢獻文章

Type I DNA Topoisomerase
Nucleosomes
DNA
Proteins
Protein
466 引文 (Scopus)

Cleavage of DNA by mammalian DNA topoisomerase II.

Liu, L-F., Rowe, T. C., Yang, L., Tewey, K. M. & Chen, G. L., 十二月 25 1983, 於 : Journal of Biological Chemistry. 258, 24, p. 15365-15370 6 p.

研究成果: 雜誌貢獻文章

Type II DNA Topoisomerase
DNA Cleavage
DNA
DNA Gyrase
Type I DNA Topoisomerase
165 引文 (Scopus)
DNA Topoisomerases
Isomerism
Superhelical DNA
Type II DNA Topoisomerase
Type I DNA Topoisomerase
31 引文 (Scopus)

HeLa topoisomerase I

Liu, L-F., 1983, 於 : Methods in Enzymology. Vol. 100, p. 133-137 5 p.

研究成果: 雜誌貢獻文章

Type I DNA Topoisomerase
Substrate Specificity
Cell Nucleus
Affinity Chromatography
HeLa Cells
1982
85 引文 (Scopus)

Intra- and intermolecular strand transfer by HeLa DNA topoisomerase I.

Halligan, B. D., Davis, J. L., Edwards, K. A. & Liu, L-F., 四月 10 1982, 於 : Journal of Biological Chemistry. 257, 7, p. 3995-4000 6 p.

研究成果: 雜誌貢獻文章

Type I DNA Topoisomerase
Single-Stranded DNA
DNA
Single-Stranded DNA Breaks
Gene Rearrangement
91 引文 (Scopus)

Recognition sites of eukaryotic DNA topoisomerase I: DNA nucleotide sequencing analysis of topo I cleavage sites on SV40 DNA

Edwards, K. A., Halligan, B. D., Davis, J. L., Nivera, N. L. & Liu, L-F., 四月 24 1982, 於 : Nucleic Acids Research. 10, 8, p. 2565-2576 12 p.

研究成果: 雜誌貢獻文章

Type I DNA Topoisomerase
Nucleotides
DNA Sequence Analysis
Sequencing
DNA
1981
271 引文 (Scopus)

A homogeneous type II DNA topoisomerase from HeLa cell nuclei.

Miller, K. G., Liu, L-F. & Englund, P. T., 九月 10 1981, 於 : Journal of Biological Chemistry. 256, 17, p. 9334-9339 6 p.

研究成果: 雜誌貢獻文章

Type II DNA Topoisomerase
Cell Nucleus
HeLa Cells
Cells
DNA
325 引文 (Scopus)
DNA Topoisomerases
Type I DNA Topoisomerase
Cell Nucleus
HeLa Cells
70 引文 (Scopus)

Knotted DNA from bacteriophage capsids

Liu, L-F., Perkocha, L., Calendar, R. & Wang, J. C., 1981, 於 : Proceedings of the National Academy of Sciences of the United States of America. 78, 9 II, p. 5498-5502 5 p.

研究成果: 雜誌貢獻文章

Capsid
Bacteriophages
DNA
Ligases
Bacteriophage P2
172 引文 (Scopus)

Novel topologically knotted DNA from bacteriophage P4 capsids: Studies with DNA topoisomerases

Liu, L-F., Davis, J. L. & Calender, R., 1981, 於 : Nucleic Acids Research. 9, 16, p. 3979-3989 11 p.

研究成果: 雜誌貢獻文章

DNA Topoisomerases
Coliphages
Nucleic Acid Conformation
Superhelical DNA
Type I DNA Topoisomerase
1980
364 引文 (Scopus)

Type II DNA topoisomerases: Enzymes that can unknot a topologically knotted DNA molecule via a reversible double-strand break

Liu, L-F., Liu, C. C. & Alberts, B. M., 1980, 於 : Cell. 19, 3, p. 697-707 11 p.

研究成果: 雜誌貢獻文章

Type II DNA Topoisomerase
Molecules
DNA
Enzymes
Circular DNA
1979
55 引文 (Scopus)
Nucleic Acid Conformation
Superhelical DNA
Type I DNA Topoisomerase
Viral DNA
Protein Binding
76 引文 (Scopus)

Nonhistone proteins HMG1 and HMG2 unwind DNA double helix

Javaherian, K., Sadeghi, M. & Liu, L-F., 八月 10 1979, 於 : Nucleic Acids Research. 6, 11, p. 3569-3580 12 p.

研究成果: 雜誌貢獻文章

HMGB2 Protein
HMGB1 Protein
Helix
Melting
Salt
155 引文 (Scopus)

T4 DNA topoisomerase: A new ATP-dependent enzyme essential for initiation of T4 bacteriophage DNA replication

Liu, L-F., Liu, C. C. & Alberts, B. M., 1979, 於 : Nature. 281, 5731, p. 456-461 6 p.

研究成果: 雜誌貢獻文章

T-Phages
Superhelical DNA
Type I DNA Topoisomerase
Bacteriophage T4
Double-Stranded DNA Breaks
1978
130 引文 (Scopus)

DNA-DNA gyrase complex: the wrapping of the DNA duplex outside the enzyme

Liu, L-F. & Wang, J. C., 1978, 於 : Cell. 15, 3, p. 979-984 6 p.

研究成果: 雜誌貢獻文章

DNA Gyrase
DNA
Enzymes
Deoxyribonuclease I
Digestion
99 引文 (Scopus)
Escherichia coli Proteins
Single-Stranded DNA
Pronase
DNA Cleavage
DNA
147 引文 (Scopus)
DNA Gyrase
Micrococcus luteus
Adenosine Triphosphate
DNA
Circular DNA
172 引文 (Scopus)

Nonhistone proteins HMG1 and HMG2 change the DNA helical structure

Javaherian, K., Liu, L-F. & Wang, J. C., 1978, 於 : Science. 199, 4335, p. 1345-1346 2 p.

研究成果: 雜誌貢獻文章

HMGB2 Protein
HMGB1 Protein
Circular DNA
DNA
Thymus Gland
1976
137 引文 (Scopus)
Circular DNA
Escherichia coli Proteins
Single-Stranded DNA
DNA
Bacteriophage M13
1975
56 引文 (Scopus)

On the degree of unwinding of the DNA helix by ethidium. II. Studies by electron microscopy

Liu, L-F. & Wang, J. C., 七月 23 1975, 於 : BBA Section Nucleic Acids And Protein Synthesis. 395, 4, p. 405-412 8 p.

研究成果: 雜誌貢獻文章

Electron Microscopy
DNA
Base Pairing
Ethidium
ethidium-DNA complex