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研究成果 1998 2019

  • 1489 引文
  • 20 h-指數
  • 30 文章
  • 2 評論/辯論
  • 2 回顧型文獻
2019
2 引文 (Scopus)

ASPM promotes prostate cancer stemness and progression by augmenting Wnt−Dvl-3−β-catenin signaling

Pai, V. C., Hsu, C. C., Chan, T. S., Liao, W. Y., Chuu, C. P., Chen, W. Y., Li, C. R., Lin, C. Y., Hwang, S. P., Chen, L. T. & Tsai, K. K., 二月 21 2019, 於 : Oncogene. 38, 8, p. 1340-1353

研究成果: 雜誌貢獻文章

Catenins
Microcephaly
Prostatic Neoplasms
Neoplastic Stem Cells
Neoplasms
1 引文 (Scopus)

Correction: ASPM promotes prostate cancer stemness and progression by augmenting Wnt−Dvl-3−β-catenin signaling (Oncogene, (2019), 38, 8, (1340-1353), 10.1038/s41388-018-0497-4)

Pai, V. C., Hsu, C. C., Chan, T. S., Liao, W. Y., Chuu, C. P., Chen, W. Y., Li, C. R., Lin, C. Y., Huang, S. P., Chen, L. T. & Tsai, K. K., 二月 21 2019, 於 : Oncogene. 38, 8, 1 p.

研究成果: 雜誌貢獻評論/辯論

Catenins
Oncogenes
Prostatic Neoplasms
2018
9 引文 (Scopus)
Proton Pump Inhibitors
Hepatocellular Carcinoma
Confidence Intervals
Hepatitis C
Hepatitis B
2017
19 引文 (Scopus)

Metronomic Chemotherapy: Direct Targeting of Cancer Cells after all?

André, N., Tsai, K., Carré, M. & Pasquier, E., 五月 1 2017, 於 : Trends in Cancer. 3, 5, p. 319-325 7 p.

研究成果: 雜誌貢獻回顧型文獻

Drug Therapy
Neoplasms
Immunotherapy
Immune System
Therapeutics
3 引文 (Scopus)

Stress stimuli induce cancer-stemness gene expression via Sp1 activation leading to therapeutic resistance in glioblastoma

Chang, K. Y., Huang, C. T., Hsu, T. I., Hsu, C. C., Liu, J. J., Chuang, C. K., Hung, J. J., Chang, W. C., Tsai, K. K. & Chuang, J. Y., 十一月 4 2017, 於 : Biochemical and Biophysical Research Communications. 493, 1, p. 14-19 6 p.

研究成果: 雜誌貢獻文章

Neoplasm Genes
Glioblastoma
Gene expression
Chemical activation
temozolomide
Immunity
Fibroblasts
Drug Therapy
Neoplasms
Carcinoma
2016
40 引文 (Scopus)

Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells

Chan, T. S., Hsu, C. C., Pai, V. C., Liao, W. Y., Huang, S. S., Tan, K. T., Yen, C. J., Hsu, S. C., Chen, W. Y., Shan, Y. S., Li, C. R., Lee, M. T., Jiang, K. Y., Chu, J. M., Lien, G. S., Weaver, V. M. & Tsai, K-C., 2016, 於 : Journal of Experimental Medicine. 213, 13, p. 2967-2988 22 p.

研究成果: 雜誌貢獻文章

Neoplastic Stem Cells
Drug Therapy
Neoplasms
Therapeutics
Chemokines
2015
22 引文 (Scopus)

Targeting chemotherapy-induced PTX3 in tumor stroma to prevent the progression of drug-resistant cancers

Chi, J. Y., Hsiao, Y. W., Li, C. F., Lo, Y. C., Lin, Z. Y., Hong, J. Y., Liu, Y. M., Han, X., Wang, S. M., Chen, B. K., Tsai, K-C. & Wang, J. M., 2015, 於 : Oncotarget. 6, 27, p. 23987-24001 15 p.

研究成果: 雜誌貢獻文章

Drug Therapy
CCAAT-Enhancer-Binding Protein-delta
Pharmaceutical Preparations
Neoplasms
Tumor Microenvironment
2014
55 引文 (Scopus)

Cancer/stroma interplay via cyclooxygenase-2 and indoleamine 2,3-dioxygenase promotes breast cancer progression

Chen, J. Y., Li, C. F., Kuo, C. C., Tsai, K. K., Hou, M. F. & Hung, W. C., 七月 25 2014, 於 : Breast Cancer Research. 16, 4, 410.

研究成果: 雜誌貢獻文章

Indoleamine-Pyrrole 2,3,-Dioxygenase
Cyclooxygenase 2
Breast Neoplasms
Neoplasms
Fibroblasts
2013
26 引文 (Scopus)

A gene expression signature of epithelial tubulogenesis and a role for ASPM in pancreatic tumor progression

Wang, W. Y., Hsu, C. C., Wang, T. Y., Li, C. R., Hou, Y. C., Chu, J. M., Lee, C. T., Liu, M. S., Su, J. J. M., Jian, K. Y., Huang, S. S., Jiang, S. S., Shan, Y. S., Lin, P. W., Shen, Y. Y., Lee, M. T. L., Chan, T. S., Chang, C. C., Chen, C. H., Chang, I. S. 及其他3, Lee, Y. L., Chen, L. T. & Tsai, K-C., 十一月 2013, 於 : Gastroenterology. 145, 5, p. 1110-1120 11 p.

研究成果: 雜誌貢獻文章

Morphogenesis
Transcriptome
Adenocarcinoma
Neoplasms
Gene Expression
29 引文 (Scopus)

Cholestane-3β, 5α, 6β-triol Suppresses Proliferation, Migration, and Invasion of Human Prostate Cancer Cells

Lin, C. Y., Huo, C., Kuo, L. K., Hiipakka, R. A., Jones, R. B., Lin, H. P., Hung, Y., Su, L. C., Tseng, J. C., Kuo, Y. Y., Wang, L. Y., Fukui, Y., Kao, Y. H., Kokontis, J. M., Yeh, C. C., Chen, L., Yang, S. D., Fu, H. H., Chen, Y. W., Tsai, K-C. 及其他2, Chang, J. Y. & Chuu, C. P., 六月 13 2013, 於 : PLoS One. 8, 6, e65734.

研究成果: 雜誌貢獻文章

prostatic neoplasms
Prostatic Neoplasms
Cells
cadherins
cells
7 引文 (Scopus)

Complete microscale profiling of tumor microangiogenesis. A microradiological methodology reveals fundamental aspects of tumor angiogenesis and yields an array of quantitative parameters for its characterization.

Chien, C. C., Kempson, I. M., Wang, C. L., Chen, H., Hwu, Y., Chen, Y. N., Lee, T-K., Tsai, K. K. C., Liu, M. S., Chang, K. Y., Yang, C. S. & Margaritondo, G., 五月 2013, 於 : Biotechnology Advances. 31, 3, p. 396-401 6 p.

研究成果: 雜誌貢獻文章

Tumors
Neoplasms
Angiogenesis Inhibitors
Oncology
Microanalysis
11 引文 (Scopus)

Molecular profiling of prostatic acinar morphogenesis identifies PDCD4 and KLF6 as tissue architecture-specific prognostic markers in prostate cancer

Li, C. R., Su, J. J. M., Wang, W. Y., Lee, M. T. L., Wang, T. Y., Jiang, K. Y., Li, C. F., Hsu, J. M., Chen, C. K., Chen, M., Jiang, S. S., Weaver, V. M. & Tsai, K. K. C., 二月 2013, 於 : American Journal of Pathology. 182, 2, p. 363-374 12 p.

研究成果: 雜誌貢獻文章

Apoptosis Regulatory Proteins
Morphogenesis
Prostatic Neoplasms
Prostate
Neoplasms
2012
36 引文 (Scopus)

Control of cyclooxygenase-2 expression and tumorigenesis by endogenous 5-methoxytryptophan

Cheng, H. H., Kuo, C. C., Yan, J. L., Chen, H. L., Lin, W. C., Wang, K. H., Tsai, K. K. C., Guvén, H., Flaberg, E., Szekelyd, L., Klein, G. & Wu, K. K., 八月 14 2012, 於 : Proceedings of the National Academy of Sciences of the United States of America. 109, 33, p. 13231-13236 6 p.

研究成果: 雜誌貢獻文章

Cyclooxygenase 2
Carcinogenesis
Neoplasms
Tryptophan
Acetylserotonin O-Methyltransferase
8 引文 (Scopus)

Effects of intravenous iron saccharate on improving severe anemia in rheumatoid arthritis patients

Chen, W. S., Liu, C. Y., Lee, H. T., Tsai, K., Lin, Y. C., Tarng, D. C., Ho, C. H. & Lin, H. Y., 三月 1 2012, 於 : Clinical Rheumatology. 31, 3, p. 469-477 9 p.

研究成果: 雜誌貢獻文章

saccharated ferric oxide
Anemia
Rheumatoid Arthritis
Iron
Hemoglobins
2 引文 (Scopus)

Erratum: The Skp2-SCF E3 ligase regulates akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis (Cell (2012) 149 (1098-1111))

Chan, C. H., Li, C. F., Yang, W. L., Gao, Y., Lee, S. W., Feng, Z., Huang, H. Y., Tsai, K. K. C., Flores, L. G., Shao, Y., Hazle, J. D., Yu, D., Wei, W., Sarbassov, D., Hung, M. C., Nakayama, K. I. & Lin, H. K., 十一月 9 2012, 於 : Cell. 151, 4, p. 913-914 2 p.

研究成果: 雜誌貢獻評論/辯論

18 引文 (Scopus)

Krüppel-like factor 10 expression as a prognostic indicator for pancreatic adenocarcinoma

Chang, V. H. S., Chu, P. Y., Peng, S. L., Mao, T. L., Shan, Y. S., Hsu, C. F., Lin, C. Y., Tsai, K-C., Yu, W. C. Y. & Ch'Ang, H. J., 八月 2012, 於 : American Journal of Pathology. 181, 2, p. 423-430 8 p.

研究成果: 雜誌貢獻文章

Pancreatic Neoplasms
Adenocarcinoma
Transforming Growth Factors
Methylation
Methyltransferases
187 引文 (Scopus)

The Skp2-SCF E3 ligase regulates akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis

Chan, C. H., Li, C. F., Yang, W. L., Gao, Y., Lee, S. W., Feng, Z., Huang, H. Y., Tsai, K. K. C., Flores, L. G., Shao, Y., Hazle, J. D., Yu, D., Wei, W., Sarbassov, D. D., Hung, M. C., Nakayama, K. I. & Lin, H. K., 五月 25 2012, 於 : Cell. 149, 5, p. 1098-1111 14 p.

研究成果: 雜誌貢獻文章

Ubiquitin-Protein Ligases
Ubiquitination
Glycolysis
TNF Receptor-Associated Factor 6
Carcinogenesis
2010
70 引文 (Scopus)

HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype

Gilbert, P. M., Mouw, J. K., Unger, M. A., Lakins, J. N., Gbegnon, M. K., Clemmer, V. B., Benezra, M., Licht, J. D., Boudreau, N. J., Tsai, K. K. C., Welm, A. L., Feldman, M. D., Weber, B. L. & Weaver, V. M., 五月 3 2010, 於 : Journal of Clinical Investigation. 120, 5, p. 1535-1550 16 p.

研究成果: 雜誌貢獻文章

開啟存取
Homeobox Genes
Breast Neoplasms
Phenotype
Aggression
Breast
2009
30 引文 (Scopus)

Low-dose radiation-induced senescent stromal fibroblasts render nearby breast cancer cells radioresistant

Tsai, K. K. C., Stuart, J., Chuang, Y. Y. E., Little, J. B. & Yuan, Z. M., 九月 2009, 於 : Radiation Research. 172, 3, p. 306-313 8 p.

研究成果: 雜誌貢獻文章

fibroblasts
breast
Fibroblasts
cancer
Radiation
2008
50 引文 (Scopus)

Deleterious effects of short-term, high-intensity exercise on immune function: Evidence from leucocyte mitochondrial alterations and apoptosis

Tuan, T. C., Hsu, T. G., Fong, M. C., Hsu, C. F., Tsai, K. K. C., Lee, C. Y. & Kong, C. W., 一月 2008, 於 : British Journal of Sports Medicine. 42, 1, p. 11-15 5 p.

研究成果: 雜誌貢獻文章

Leukocytes
Exercise
Apoptosis
Membrane Potentials
Neutrophils
2005
23 引文 (Scopus)

c-Abl regulates Early Growth Response Protein (EGR1) in response to oxidative stress

Stuart, J. R., Kawai, H., Tsai, K. K. C., Chuang, E. Y. & Yuan, Z. M., 十二月 8 2005, 於 : Oncogene. 24, 55, p. 8085-8092 8 p.

研究成果: 雜誌貢獻文章

Early Growth Response Protein 1
Oxidative Stress
Growth
Phosphotransferases
Apoptosis
80 引文 (Scopus)

Cellular mechanisms for low-dose ionizing radiation-induced perturbation of the breast tissue microenvironment

Tsai, K. K. C., Chuang, Y. Y. E., Little, J. B. & Yuan, Z. M., 八月 1 2005, 於 : Cancer Research. 65, 15, p. 6734-6744 11 p.

研究成果: 雜誌貢獻文章

Ionizing Radiation
Breast
Fibroblasts
Secreted Matrix Metalloproteinases
Carcinogenesis
2004
6 引文 (Scopus)

Leukocyte mitochondrial alterations after cardiac surgery involving cardiopulmonary bypass: clinical correlations.

Kong, C. W., Huang, C. H., Hsu, T. G., Tsai, K. K. C., Hsu, C. F., Huang, M. C. & Chen, C. L., 四月 2004, 於 : Shock. 21, 4, p. 315-319 5 p.

研究成果: 雜誌貢獻文章

Cardiopulmonary Bypass
Membrane Potentials
Thoracic Surgery
Leukocytes
Oxidants
2003
83 引文 (Scopus)

c-Abl stabilizes p73 by a phosphorylation-augmented interaction

Tsai, K. K. C. & Yuan, Z. M., 六月 15 2003, 於 : Cancer Research. 63, 12, p. 3418-3424 7 p.

研究成果: 雜誌貢獻文章

Phosphorylation
Protein Isoforms
Cisplatin
DNA Damage
Tyrosine
135 引文 (Scopus)

DNA Damage-induced MDMX Degradation Is Mediated by MDM2

Kawai, H., Wiederschain, D., Kitao, H., Stuart, J., Tsai, K. K. C. & Yuan, Z. M., 十一月 14 2003, 於 : Journal of Biological Chemistry. 278, 46, p. 45946-45953 8 p.

研究成果: 雜誌貢獻文章

DNA Damage
Chemical activation
Degradation
DNA
Proto-Oncogene Proteins c-mdm2
2002
54 引文 (Scopus)

Effect of baicalein on apoptosis of the human Hep G2 cell line was induced by mitochondrial dysfunction

Chang, W. H., Chen, C. H., Gau, R. J., Lin, C. C., Tsai, C. L., Tsai, K. & Lu, F. J., 2002, 於 : Planta Medica. 68, 4, p. 302-306 5 p.

研究成果: 雜誌貢獻文章

Hep G2 Cells
Cells
Apoptosis
Mitochondria
Mitochondrial Membrane Potential
53 引文 (Scopus)

Leukocyte mitochondria alterations after aerobic exercise in trained human subjects

Hsu, T. G., Hsu, K. M., Kong, C. W., Lu, F. J., Cheng, H. & Tsai, K., 2002, 於 : Medicine and Science in Sports and Exercise. 34, 3, p. 438-442 5 p.

研究成果: 雜誌貢獻文章

Mitochondria
Leukocytes
Exercise
Membrane Potentials
Apoptosis
2001
9 引文 (Scopus)

Age-related changes in the mitochondrial depolarization induced by oxidative injury in human peripheral blood leukocytes

Tsai, K., Hsu, T. G., Lu, F. J., Hsu, C. F., Liu, T. Y. & Kong, C. W., 2001, 於 : Free Radical Research. 35, 4, p. 395-403 9 p.

研究成果: 雜誌貢獻文章

tert-Butylhydroperoxide
Mitochondria
Depolarization
Oxidants
Leukocytes
14 引文 (Scopus)

Leukocyte mitochondria depolarization and apoptosis in advanced heart failure: Clinical correlations and effect of therapy

Kong, C. W., Hsu, T. G., Lu, F. J., Chan, W. L. & Tsai, K., 十一月 15 2001, 於 : Journal of the American College of Cardiology. 38, 6, p. 1693-1700 8 p.

研究成果: 雜誌貢獻文章

Mitochondria
Leukocytes
Heart Failure
Apoptosis
Membrane Potentials
172 引文 (Scopus)

Oxidative DNA damage in human peripheral leukocytes induced by massive aerobic exercise

Tsai, K., Hsu, T. G., Hsu, K. M., Cheng, H., Liu, T. Y., Hsu, C. F. & Kong, C. W., 十二月 1 2001, 於 : Free Radical Biology and Medicine. 31, 11, p. 1465-1472 8 p.

研究成果: 雜誌貢獻文章

DNA Damage
Leukocytes
Endonucleases
Exercise
DNA
2000
53 引文 (Scopus)

Is the endogenous peroxyl-radical scavenging capacity of plasma protective in systemic inflammatory disorders in humans?

Tsai, K., Hsu, T. G., Kong, C. W., Lin, K. C. & Fung-Jou, L. U., 三月 15 2000, 於 : Free Radical Biology and Medicine. 28, 6, p. 926-933 8 p.

研究成果: 雜誌貢獻文章

Systemic Inflammatory Response Syndrome
Scavenging
Plasmas
Antioxidants
Oxidative stress
58 引文 (Scopus)

Magnolol attenuates peroxidative damage and improves survival of rats with sepsis

Kong, C. W., Tsai, K., Chin, J. H., Chan, W. L. & Hong, C. Y., 一月 2000, 於 : Shock. 13, 1, p. 24-28 5 p.

研究成果: 雜誌貢獻文章

Sepsis
Punctures
Antioxidants
Magnolia
magnolol
1998
124 引文 (Scopus)

Oxidative stress: An important phenomenon with pathogenetic significance in the progression of acute pancreatitis

Tsai, K., Wang, S. S., Chen, T-G., Kong, C-W., Chang, F-Y., Lee, S-D. & Lu, F. J., 1998, 於 : Gut. 42, 6, p. 850-855 6 p.

研究成果: 雜誌貢獻文章

Pancreatitis
Oxidative Stress
Dehydroascorbic Acid
Superoxides
Tocopherols