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研究成果

  • 1565 引文
  • 20 h-指數
  • 34 文章
  • 4 回顧型文獻
  • 2 評論/辯論
2020

A multicenter, phase I/II trial of biweekly S-1, leucovorin, oxaliplatin and gemcitabine in metastatic pancreatic adenocarcinoma–TCOG T1211 study

Chiang, N. J., Tsai, K. K., Hsiao, C. F., Yang, S. H., Hsiao, H. H., Shen, W. C., Hsu, C., Lin, Y. L., Chen, J. S., Shan, Y. S. & Chen, L. T., 一月 2020, 於 : European Journal of Cancer. 124, p. 123-130 8 p.

研究成果: 雜誌貢獻文章

Dishevelled 1-Regulated Superpotent Cancer Stem Cells Mediate Wnt Heterogeneity and Tumor Progression in Hepatocellular Carcinoma

Liao, W. Y., Hsu, C. C., Chan, T. S., Yen, C. J., Chen, W. Y., Pan, H. W. & Tsai, K. K., 三月 10 2020, 於 : Stem Cell Reports. 14, 3, p. 462-477 16 p.

研究成果: 雜誌貢獻文章

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2019

ASPM promotes prostate cancer stemness and progression by augmenting Wnt−Dvl-3−β-catenin signaling

Pai, V. C., Hsu, C. C., Chan, T. S., Liao, W. Y., Chuu, C. P., Chen, W-Y., Li, C. R., Lin, C. Y., Huang, S. P., Chen, L. T. & Tsai, K. K., 二月 21 2019, 於 : Oncogene. 38, 8, p. 1340-1353 14 p.

研究成果: 雜誌貢獻文章

9 引文 斯高帕斯(Scopus)

Correction: ASPM promotes prostate cancer stemness and progression by augmenting Wnt−Dvl-3−β-catenin signaling (Oncogene, (2019), 38, 8, (1340-1353), 10.1038/s41388-018-0497-4)

Pai, V. C., Hsu, C. C., Chan, T. S., Liao, W. Y., Chuu, C. P., Chen, W-Y., Li, C. R., Lin, C. Y., Huang, S. P., Chen, L. T. & Tsai, K. K., 二月 21 2019, 於 : Oncogene. 38, 8, p. 1354 1 p.

研究成果: 雜誌貢獻評論/辯論

3 引文 斯高帕斯(Scopus)

Histone demethylase KDM4C stimulates the proliferation of prostate cancer cells via activation of AKT and c-Myc

Lin, C. Y., Wang, B. J., Chen, B. C., Tseng, J. C., Jiang, S. S., Tsai, K. K., Shen, Y. Y., Yuh, C. H., Sie, Z. L., Wang, W. C., Kung, H. J. & Chuu, C. P., 十一月 13 2019, 於 : Cancers. 11, 11, 1785.

研究成果: 雜誌貢獻文章

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2 引文 斯高帕斯(Scopus)

The differential distributions of ASPM isoforms and their roles in Wnt signaling, cell cycle progression, and pancreatic cancer prognosis

Hsu, C. C., Liao, W. Y., Chan, T. S., Chen, W. Y., Lee, C. T., Shan, Y. S., Huang, P. J., Hou, Y. C., Li, C. R. & Tsai, K. K., 十二月 1 2019, 於 : Journal of Pathology. 249, 4, p. 498-508 11 p.

研究成果: 雜誌貢獻文章

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4 引文 斯高帕斯(Scopus)

The multifaceted role of mesenchymal stem cells in cancer

Timaner, M., Tsai, K. K. & Shaked, Y., 一月 1 2019, (接受/付印) 於 : Seminars in Cancer Biology.

研究成果: 雜誌貢獻回顧型文獻

3 引文 斯高帕斯(Scopus)
2018
16 引文 斯高帕斯(Scopus)
2017

Metronomic Chemotherapy: Direct Targeting of Cancer Cells after all?

André, N., Tsai, K., Carré, M. & Pasquier, E., 五月 1 2017, 於 : Trends in Cancer. 3, 5, p. 319-325 7 p.

研究成果: 雜誌貢獻回顧型文獻

20 引文 斯高帕斯(Scopus)

Stress stimuli induce cancer-stemness gene expression via Sp1 activation leading to therapeutic resistance in glioblastoma

Chang, K. Y., Huang, C. T., Hsu, T. I., Hsu, C. C., Liu, J. J., Chuang, C. K., Hung, J. J., Chang, W. C., Tsai, K. K. & Chuang, J. Y., 十一月 4 2017, 於 : Biochemical and Biophysical Research Communications. 493, 1, p. 14-19 6 p.

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)
2016

Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells

Chan, T. S., Hsu, C. C., Pai, V. C., Liao, W. Y., Huang, S. S., Tan, K. T., Yen, C. J., Hsu, S. C., Chen, W. Y., Shan, Y. S., Li, C. R., Lee, M. T., Jiang, K. Y., Chu, J. M., Lien, G. S., Weaver, V. M. & Tsai, K-C., 2016, 於 : Journal of Experimental Medicine. 213, 13, p. 2967-2988 22 p.

研究成果: 雜誌貢獻文章

44 引文 斯高帕斯(Scopus)
2015

Targeting chemotherapy-induced PTX3 in tumor stroma to prevent the progression of drug-resistant cancers

Chi, J. Y., Hsiao, Y. W., Li, C. F., Lo, Y. C., Lin, Z. Y., Hong, J. Y., Liu, Y. M., Han, X., Wang, S. M., Chen, B. K., Tsai, K-C. & Wang, J. M., 2015, 於 : Oncotarget. 6, 27, p. 23987-24001 15 p.

研究成果: 雜誌貢獻文章

23 引文 斯高帕斯(Scopus)
2014

Cancer/stroma interplay via cyclooxygenase-2 and indoleamine 2,3-dioxygenase promotes breast cancer progression

Chen, J. Y., Li, C. F., Kuo, C. C., Tsai, K. K., Hou, M. F. & Hung, W. C., 七月 25 2014, 於 : Breast Cancer Research. 16, 4, 410.

研究成果: 雜誌貢獻文章

60 引文 斯高帕斯(Scopus)
2013

A gene expression signature of epithelial tubulogenesis and a role for ASPM in pancreatic tumor progression

Wang, W. Y., Hsu, C. C., Wang, T. Y., Li, C. R., Hou, Y. C., Chu, J. M., Lee, C. T., Liu, M. S., Su, J. J. M., Jian, K. Y., Huang, S. S., Jiang, S. S., Shan, Y. S., Lin, P. W., Shen, Y. Y., Lee, M. T. L., Chan, T. S., Chang, C. C., Chen, C. H., Chang, I. S. 及其他3, Lee, Y. L., Chen, L. T. & Tsai, K-C., 十一月 2013, 於 : Gastroenterology. 145, 5, p. 1110-1120 11 p.

研究成果: 雜誌貢獻文章

35 引文 斯高帕斯(Scopus)

Cholestane-3β, 5α, 6β-triol Suppresses Proliferation, Migration, and Invasion of Human Prostate Cancer Cells

Lin, C. Y., Huo, C., Kuo, L. K., Hiipakka, R. A., Jones, R. B., Lin, H. P., Hung, Y., Su, L. C., Tseng, J. C., Kuo, Y. Y., Wang, L. Y., Fukui, Y., Kao, Y. H., Kokontis, J. M., Yeh, C. C., Chen, L., Yang, S. D., Fu, H. H., Chen, Y. W., Tsai, K-C. 及其他2, Chang, J. Y. & Chuu, C. P., 六月 13 2013, 於 : PLoS One. 8, 6, e65734.

研究成果: 雜誌貢獻文章

30 引文 斯高帕斯(Scopus)

Complete microscale profiling of tumor microangiogenesis. A microradiological methodology reveals fundamental aspects of tumor angiogenesis and yields an array of quantitative parameters for its characterization.

Chien, C. C., Kempson, I. M., Wang, C. L., Chen, H., Hwu, Y., Chen, Y. N., Lee, T-K., Tsai, K. K. C., Liu, M. S., Chang, K. Y., Yang, C. S. & Margaritondo, G., 五月 2013, 於 : Biotechnology Advances. 31, 3, p. 396-401 6 p.

研究成果: 雜誌貢獻文章

7 引文 斯高帕斯(Scopus)

Molecular profiling of prostatic acinar morphogenesis identifies PDCD4 and KLF6 as tissue architecture-specific prognostic markers in prostate cancer

Li, C. R., Su, J. J. M., Wang, W. Y., Lee, M. T. L., Wang, T. Y., Jiang, K. Y., Li, C. F., Hsu, J. M., Chen, C. K., Chen, M., Jiang, S. S., Weaver, V. M. & Tsai, K. K. C., 二月 2013, 於 : American Journal of Pathology. 182, 2, p. 363-374 12 p.

研究成果: 雜誌貢獻文章

11 引文 斯高帕斯(Scopus)
2012

Control of cyclooxygenase-2 expression and tumorigenesis by endogenous 5-methoxytryptophan

Cheng, H. H., Kuo, C. C., Yan, J. L., Chen, H. L., Lin, W. C., Wang, K. H., Tsai, K. K. C., Guvén, H., Flaberg, E., Szekelyd, L., Klein, G. & Wu, K. K., 八月 14 2012, 於 : Proceedings of the National Academy of Sciences of the United States of America. 109, 33, p. 13231-13236 6 p.

研究成果: 雜誌貢獻文章

39 引文 斯高帕斯(Scopus)

Effects of intravenous iron saccharate on improving severe anemia in rheumatoid arthritis patients

Chen, W. S., Liu, C. Y., Lee, H. T., Tsai, K., Lin, Y. C., Tarng, D. C., Ho, C. H. & Lin, H. Y., 三月 1 2012, 於 : Clinical Rheumatology. 31, 3, p. 469-477 9 p.

研究成果: 雜誌貢獻文章

9 引文 斯高帕斯(Scopus)

Erratum: The Skp2-SCF E3 ligase regulates akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis (Cell (2012) 149 (1098-1111))

Chan, C. H., Li, C. F., Yang, W. L., Gao, Y., Lee, S. W., Feng, Z., Huang, H. Y., Tsai, K. K. C., Flores, L. G., Shao, Y., Hazle, J. D., Yu, D., Wei, W., Sarbassov, D., Hung, M. C., Nakayama, K. I. & Lin, H. K., 十一月 9 2012, 於 : Cell. 151, 4, p. 913-914 2 p.

研究成果: 雜誌貢獻評論/辯論

4 引文 斯高帕斯(Scopus)

Krüppel-like factor 10 expression as a prognostic indicator for pancreatic adenocarcinoma

Chang, V. H. S., Chu, P. Y., Peng, S. L., Mao, T. L., Shan, Y. S., Hsu, C. F., Lin, C. Y., Tsai, K-C., Yu, W. C. Y. & Ch'Ang, H. J., 八月 2012, 於 : American Journal of Pathology. 181, 2, p. 423-430 8 p.

研究成果: 雜誌貢獻文章

18 引文 斯高帕斯(Scopus)

The Skp2-SCF E3 ligase regulates akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis

Chan, C. H., Li, C. F., Yang, W. L., Gao, Y., Lee, S. W., Feng, Z., Huang, H. Y., Tsai, K. K. C., Flores, L. G., Shao, Y., Hazle, J. D., Yu, D., Wei, W., Sarbassov, D. D., Hung, M. C., Nakayama, K. I. & Lin, H. K., 五月 25 2012, 於 : Cell. 149, 5, p. 1098-1111 14 p.

研究成果: 雜誌貢獻文章

201 引文 斯高帕斯(Scopus)
2010

HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype

Gilbert, P. M., Mouw, J. K., Unger, M. A., Lakins, J. N., Gbegnon, M. K., Clemmer, V. B., Benezra, M., Licht, J. D., Boudreau, N. J., Tsai, K. K. C., Welm, A. L., Feldman, M. D., Weber, B. L. & Weaver, V. M., 五月 3 2010, 於 : Journal of Clinical Investigation. 120, 5, p. 1535-1550 16 p.

研究成果: 雜誌貢獻文章

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71 引文 斯高帕斯(Scopus)
2009

Low-dose radiation-induced senescent stromal fibroblasts render nearby breast cancer cells radioresistant

Tsai, K. K. C., Stuart, J., Chuang, Y. Y. E., Little, J. B. & Yuan, Z. M., 九月 2009, 於 : Radiation Research. 172, 3, p. 306-313 8 p.

研究成果: 雜誌貢獻文章

30 引文 斯高帕斯(Scopus)
2008

Deleterious effects of short-term, high-intensity exercise on immune function: Evidence from leucocyte mitochondrial alterations and apoptosis

Tuan, T. C., Hsu, T. G., Fong, M. C., Hsu, C. F., Tsai, K. K. C., Lee, C. Y. & Kong, C. W., 一月 2008, 於 : British Journal of Sports Medicine. 42, 1, p. 11-15 5 p.

研究成果: 雜誌貢獻文章

51 引文 斯高帕斯(Scopus)
2005

c-Abl regulates Early Growth Response Protein (EGR1) in response to oxidative stress

Stuart, J. R., Kawai, H., Tsai, K. K. C., Chuang, E. Y. & Yuan, Z. M., 十二月 8 2005, 於 : Oncogene. 24, 55, p. 8085-8092 8 p.

研究成果: 雜誌貢獻文章

23 引文 斯高帕斯(Scopus)

Cellular mechanisms for low-dose ionizing radiation-induced perturbation of the breast tissue microenvironment

Tsai, K. K. C., Chuang, Y. Y. E., Little, J. B. & Yuan, Z. M., 八月 1 2005, 於 : Cancer Research. 65, 15, p. 6734-6744 11 p.

研究成果: 雜誌貢獻文章

81 引文 斯高帕斯(Scopus)
2004

Leukocyte mitochondrial alterations after cardiac surgery involving cardiopulmonary bypass: clinical correlations.

Kong, C. W., Huang, C. H., Hsu, T. G., Tsai, K. K. C., Hsu, C. F., Huang, M. C. & Chen, C. L., 四月 2004, 於 : Shock. 21, 4, p. 315-319 5 p.

研究成果: 雜誌貢獻文章

6 引文 斯高帕斯(Scopus)
2003

c-Abl stabilizes p73 by a phosphorylation-augmented interaction

Tsai, K. K. C. & Yuan, Z. M., 六月 15 2003, 於 : Cancer Research. 63, 12, p. 3418-3424 7 p.

研究成果: 雜誌貢獻文章

83 引文 斯高帕斯(Scopus)

DNA Damage-induced MDMX Degradation Is Mediated by MDM2

Kawai, H., Wiederschain, D., Kitao, H., Stuart, J., Tsai, K. K. C. & Yuan, Z. M., 十一月 14 2003, 於 : Journal of Biological Chemistry. 278, 46, p. 45946-45953 8 p.

研究成果: 雜誌貢獻文章

136 引文 斯高帕斯(Scopus)
2002

Effect of baicalein on apoptosis of the human Hep G2 cell line was induced by mitochondrial dysfunction

Chang, W. H., Chen, C. H., Gau, R. J., Lin, C. C., Tsai, C. L., Tsai, K. & Lu, F. J., 2002, 於 : Planta Medica. 68, 4, p. 302-306 5 p.

研究成果: 雜誌貢獻文章

55 引文 斯高帕斯(Scopus)

Leukocyte mitochondria alterations after aerobic exercise in trained human subjects

Hsu, T. G., Hsu, K. M., Kong, C. W., Lu, F. J., Cheng, H. & Tsai, K., 2002, 於 : Medicine and Science in Sports and Exercise. 34, 3, p. 438-442 5 p.

研究成果: 雜誌貢獻文章

53 引文 斯高帕斯(Scopus)
2001

Age-related changes in the mitochondrial depolarization induced by oxidative injury in human peripheral blood leukocytes

Tsai, K., Hsu, T. G., Lu, F. J., Hsu, C. F., Liu, T. Y. & Kong, C. W., 2001, 於 : Free Radical Research. 35, 4, p. 395-403 9 p.

研究成果: 雜誌貢獻文章

9 引文 斯高帕斯(Scopus)

Leukocyte mitochondria depolarization and apoptosis in advanced heart failure: Clinical correlations and effect of therapy

Kong, C. W., Hsu, T. G., Lu, F. J., Chan, W. L. & Tsai, K., 十一月 15 2001, 於 : Journal of the American College of Cardiology. 38, 6, p. 1693-1700 8 p.

研究成果: 雜誌貢獻文章

14 引文 斯高帕斯(Scopus)

Oxidative DNA damage in human peripheral leukocytes induced by massive aerobic exercise

Tsai, K., Hsu, T. G., Hsu, K. M., Cheng, H., Liu, T. Y., Hsu, C. F. & Kong, C. W., 十二月 1 2001, 於 : Free Radical Biology and Medicine. 31, 11, p. 1465-1472 8 p.

研究成果: 雜誌貢獻文章

174 引文 斯高帕斯(Scopus)
2000

Is the endogenous peroxyl-radical scavenging capacity of plasma protective in systemic inflammatory disorders in humans?

Tsai, K., Hsu, T. G., Kong, C. W., Lin, K. C. & Fung-Jou, L. U., 三月 15 2000, 於 : Free Radical Biology and Medicine. 28, 6, p. 926-933 8 p.

研究成果: 雜誌貢獻文章

54 引文 斯高帕斯(Scopus)

Magnolol attenuates peroxidative damage and improves survival of rats with sepsis

Kong, C. W., Tsai, K., Chin, J. H., Chan, W. L. & Hong, C. Y., 一月 2000, 於 : Shock. 13, 1, p. 24-28 5 p.

研究成果: 雜誌貢獻文章

58 引文 斯高帕斯(Scopus)
1998

Oxidative stress: An important phenomenon with pathogenetic significance in the progression of acute pancreatitis

Tsai, K., Wang, S. S., Chen, T-G., Kong, C-W., Chang, F-Y., Lee, S-D. & Lu, F. J., 1998, 於 : Gut. 42, 6, p. 850-855 6 p.

研究成果: 雜誌貢獻文章

126 引文 斯高帕斯(Scopus)