• 4595 引文
  • 35 h-指數
1992 …2020

每年研究成果

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研究成果

篩選
文章
2020

Focal TLR4 activation mediates disturbed flow-induced endothelial inflammation

Qu, D., Wang, L., Huo, M., Song, W., Lau, C. W., Xu, J., Xu, A., Yao, X., Chiu, J. J., Tian, X. Y. & Huang, Y., 一月 1 2020, 於 : Cardiovascular Research. 116, 1, p. 226-236 11 p.

研究成果: 雜誌貢獻文章

8 引文 斯高帕斯(Scopus)

Inhibition of miR-21 alleviated cardiac perivascular fibrosis via repressing EndMT in T1DM

Li, Q., Yao, Y., Shi, S., Zhou, M., Zhou, Y., Wang, M., Chiu, J. J., Huang, Z., Zhang, W., Liu, M., Wang, Q. & Tu, X., 一月 1 2020, 於 : Journal of Cellular and Molecular Medicine. 24, 1, p. 910-920 11 p.

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3 引文 斯高帕斯(Scopus)

Reduction in MicroRNA-4488 Expression Induces NFκB Translocation in Venous Endothelial Cells Under Arterial Flow

Fang, S. Y., Huang, C. W., Huang, T. C., Yadav, A., Chiu, J. J. & Wu, C. C., 2020, (接受/付印) 於 : Cardiovascular Drugs and Therapy.

研究成果: 雜誌貢獻文章

2018

Differential regulations of fibronectin and laminin in Smad2 activation in vascular endothelial cells in response to disturbed flow

Yang, T. L., Lee, P. L., Lee, D. Y., Wang, W. L., Wei, S. Y., Lee, C. I. & Chiu, J. J., 一月 2 2018, 於 : Journal of Biomedical Science. 25, 1, 1.

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4 引文 斯高帕斯(Scopus)

Induction of microRNA-10a using retinoic acid receptor-α and retinoid x receptor-α agonists inhibits atherosclerotic lesion formation

Lee, D. Y., Yang, T. L., Huang, Y. H., Lee, C. I., Chen, L. J., Shih, Y. T., Wei, S. Y., Wang, W. L., Wu, C. C. & Chiu, J. J., 四月 2018, 於 : Atherosclerosis. 271, p. 36-44 9 p.

研究成果: 雜誌貢獻文章

10 引文 斯高帕斯(Scopus)

Matrix stiffness determines the phenotype of vascular smooth muscle cell in vitro and in vivo: Role of DNA methyltransferase 1

Xie, S. A., Zhang, T., Wang, J., Zhao, F., Zhang, Y. P., Yao, W. J., Hur, S. S., Yeh, Y. T., Pang, W., Zheng, L. S., Fan, Y. B., Kong, W., Wang, X., Chiu, J. J. & Zhou, J., 二月 2018, 於 : Biomaterials. 155, p. 203-216 14 p.

研究成果: 雜誌貢獻文章

22 引文 斯高帕斯(Scopus)

MicroRNA-21 and venous neointimal hyperplasia of dialysis vascular access

Wu, C. C., Chen, L. J., Hsieh, M. Y., Lo, C. M., Lin, M. H., Tsai, H. E., Song, H. L. & Chiu, J. J., 一月 1 2018, 於 : Clinical Journal of the American Society of Nephrology. 13, 11, p. 1712-1720 9 p.

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3 引文 斯高帕斯(Scopus)

Three-dimensional forces exerted by leukocytes and vascular endothelial cells dynamically facilitate diapedesis

Yeh, Y. T., Serrano, R., François, J., Chiu, J. J., Li, Y. S. J., Del Álamo, J. C., Chien, S. & Lasheras, J. C., 一月 2 2018, 於 : Proceedings of the National Academy of Sciences of the United States of America. 115, 1, p. 133-138 6 p.

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15 引文 斯高帕斯(Scopus)
2017

MicroRNA-10a is crucial for endothelial response to different flow patterns via interaction of retinoid acid receptors and histone deacetylases

Lee, D. Y., Lin, T. E., Lee, C. I., Zhou, J., Huang, Y. H., Lee, P. L., Shih, Y. T., Chien, S. & Chiu, J. J., 二月 21 2017, 於 : Proceedings of the National Academy of Sciences of the United States of America. 114, 8, p. 2072-2077 6 p.

研究成果: 雜誌貢獻文章

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20 引文 斯高帕斯(Scopus)
2016

Integrin-YAP/TAZ-JNK cascade mediates atheroprotective effect of unidirectional shear flow

Huang, Y., Wang, L., Luo, J. Y., Li, B., Tian, X. Y., Chen, L. J., Huang, Y., Liu, J., Deng, D., Lau, C. W., Wan, S., Ai, DI., Mak, K. L. K., Tong, K. K., Kwan, K. M., Wang, N., Chiu, J. J. & Zhu, Y., 十二月 22 2016, 於 : Nature. 540, 7634, p. 579-582 4 p.

研究成果: 雜誌貢獻文章

147 引文 斯高帕斯(Scopus)
2015

Endothelial progenitors promote hepatocarcinoma intrahepatic metastasis through monocyte chemotactic protein-1 induction of microRNA-21

Shih, Y. T., Wang, M. C., Zhou, J., Peng, H. H., Lee, D. Y. & Chiu, J. J., 七月 1 2015, 於 : Gut. 64, 7, p. 1132-1147 16 p.

研究成果: 雜誌貢獻文章

21 引文 斯高帕斯(Scopus)

MicroRNA mediation of endothelial inflammatory response to smooth muscle cells and its inhibition by atheroprotective shear stress

Chen, L. J., Chuang, L., Huang, Y. H., Zhou, J., Lim, S. H., Lee, C. I., Lin, W. W., Lin, T. E., Wang, W. L., Chen, L., Chien, S. & Chiu, J. J., 三月 27 2015, 於 : Circulation Research. 116, 7, p. 1157-1169 13 p.

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28 引文 斯高帕斯(Scopus)

Shear stress regulates endothelial cell autophagy via redox regulation and Sirt1 expression

Liu, J., Bi, X., Chen, T., Zhang, Q., Wang, S. X., Chiu, J. J., Liu, G. S., Zhang, Y., Bu, P. & Jiang, F., 七月 1 2015, 於 : Cell Death and Disease. 6, 7, e1827.

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63 引文 斯高帕斯(Scopus)
2014
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14 引文 斯高帕斯(Scopus)

Protein kinase C-δ and -β coordinate flow-induced directionality and deformation of migratory human blood T-lymphocytes

Wei, S. Y., Lin, T. E., Wang, W. L., Lee, P. L., Tsai, M. C. & Chiu, J. J., 十二月 1 2014, 於 : Journal of Molecular Cell Biology. 6, 6, p. 458-472 15 p.

研究成果: 雜誌貢獻文章

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7 引文 斯高帕斯(Scopus)

Regulation of fibrillar collagen-mediated smooth muscle cell proliferation in response to chemical stimuli by telomere reverse transcriptase through c-Myc

Wang, W. L., Yeh, Y. T., Chen, L. J. & Chiu, J. J., 四月 1 2014, 於 : Biomaterials. 35, 12, p. 3829-3839 11 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)
2013

Activation of PPAR-α induces cell cycle arrest and inhibits transforming growth factor-β1 induction of smooth muscle cell phenotype in 10T1/2 mesenchymal cells

Lien, S. C., Wei, S. Y., Chang, S. F., Chang, M. D. T., Chang, J. Y. & Chiu, J. J., 五月 1 2013, 於 : Cellular Signalling. 25, 5, p. 1252-1263 12 p.

研究成果: 雜誌貢獻文章

11 引文 斯高帕斯(Scopus)

BMP receptor-integrin interaction mediates responses of vascular endothelial Smad1/5 and proliferation to disturbed flow

Zhou, J., Lee, P. L., Lee, C. I., Wei, S. Y., Lim, S. H., Lin, T. E., Chien, S. & Chiu, J. J., 四月 1 2013, 於 : Journal of Thrombosis and Haemostasis. 11, 4, p. 741-755 15 p.

研究成果: 雜誌貢獻文章

33 引文 斯高帕斯(Scopus)

CBAP Functions as a Novel Component in Chemokine-Induced ZAP70-Mediated T-Cell Adhesion and Migration

Chiang, Y. J., Ho, K. C., Sun, C. T., Chiu, J. J., Lee, F. J., Liao, F., Yang-Yen, H. F. & Yen, J. J. Y., 四月 19 2013, 於 : PLoS ONE. 8, 4, e61761.

研究成果: 雜誌貢獻文章

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6 引文 斯高帕斯(Scopus)

Mechanical regulation of cancer cell apoptosis and autophagy: Roles of bone morphogenetic protein receptor, Smad1/5, and p38 MAPK

Lien, S. C., Chang, S. F., Lee, P. L., Wei, S. Y., Chang, M. D. T., Chang, J. Y. & Chiu, J. J., 十二月 1 2013, 於 : Biochimica et Biophysica Acta - Molecular Cell Research. 1833, 12, p. 3124-3133 10 p.

研究成果: 雜誌貢獻文章

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55 引文 斯高帕斯(Scopus)

Mechanical regulation of epigenetics in vascular biology and pathobiology

Chen, L. J., Wei, S. Y. & Chiu, J. J., 四月 1 2013, 於 : Journal of Cellular and Molecular Medicine. 17, 4, p. 437-448 12 p.

研究成果: 雜誌貢獻文章

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45 引文 斯高帕斯(Scopus)

Regulation of vascular smooth muscle cell turnover by endothelial cell-secreted microRNA-126 role of shear stress

Zhou, J., Li, Y. S., Nguyen, P., Wang, K. C., Weiss, A., Kuo, Y. C., Chiu, J. J., Shyy, J. Y. & Chien, S., 六月 1 2013, 於 : Circulation Research. 113, 1, p. 40-51 12 p.

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141 引文 斯高帕斯(Scopus)
2012

Convergence of physical and chemical signaling in the modulation of vascular smooth muscle cell cycle and proliferation by fibrillar collagen-regulated P66Shc

Yeh, Y. T., Lee, C. I., Lim, S. H., Chen, L. J., Wang, W. L., Chuang, Y. J. & Chiu, J. J., 十月 1 2012, 於 : Biomaterials. 33, 28, p. 6728-6738 11 p.

研究成果: 雜誌貢獻文章

5 引文 斯高帕斯(Scopus)

Force-specific activation of Smad1/5 regulates vascular endothelial cell cycle progression in response to disturbed flow

Zhou, J., Lee, P. L., Tsai, C. S., Lee, C. I., Yang, T. L., Chuang, H. S., Lin, W. W., Lin, T. E., Lim, S. H., Wei, S. Y., Chen, Y. L., Chien, S. & Chiu, J. J., 五月 15 2012, 於 : Proceedings of the National Academy of Sciences of the United States of America. 109, 20, p. 7770-7775 6 p.

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51 引文 斯高帕斯(Scopus)

Matrix Stiffness Regulates Endothelial Cell Proliferation through Septin 9

Yeh, Y. T., Hur, S. S., Chang, J., Wang, K. C., Chiu, J. J., Li, Y. S. & Chien, S., 十月 31 2012, 於 : PLoS ONE. 7, 10, e46889.

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65 引文 斯高帕斯(Scopus)

Modulation of chemotactic and pro-inflammatory activities of endothelial progenitor cells by hepatocellular carcinoma

Shih, Y. T., Wang, M. C., Peng, H. H., Chen, T. F., Chen, L., Chang, J. Y. & Chiu, J. J., 三月 1 2012, 於 : Cellular Signalling. 24, 3, p. 779-793 15 p.

研究成果: 雜誌貢獻文章

15 引文 斯高帕斯(Scopus)

Role of histone deacetylases in transcription factor regulation and cell cycle modulation in endothelial cells in response to disturbed flow

Lee, D. Y., Lee, C. I., Lin, T. E., Lim, S. H., Zhou, J., Tseng, Y. C., Chien, S. & Chiu, J. J., 二月 7 2012, 於 : Proceedings of the National Academy of Sciences of the United States of America. 109, 6, p. 1967-1972 6 p.

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86 引文 斯高帕斯(Scopus)

β2-Integrin and Notch-1 differentially regulate CD34 +CD31+ cell plasticity in vascular niches

Shih, Y. T., Wang, M. C., Yang, T. L., Zhou, J., Lee, D. Y., Lee, P. L., Yet, S. F. & Chiu, J. J., 十一月 1 2012, 於 : Cardiovascular Research. 96, 2, p. 296-307 12 p.

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3 引文 斯高帕斯(Scopus)
2011

MicroRNA-21 targets peroxisome proliferators-activated receptor-α in an autoregulatory loop to modulate flow-induced endothelial inflammation

Zhou, J., Wang, K. C., Wu, W., Subramaniam, S., Shyy, J. Y. J., Chiu, J. J., Li, J. Y. S. & Chien, S., 六月 21 2011, 於 : Proceedings of the National Academy of Sciences of the United States of America. 108, 25, p. 10355-10360 6 p.

研究成果: 雜誌貢獻文章

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240 引文 斯高帕斯(Scopus)

Salvianolic acid B inhibits low-density lipoprotein oxidation and neointimal hyperplasia in endothelium-denuded hypercholesterolaemic rabbits

Yang, T. L., Lin, F-Y., Chen, Y. H., Chiu, J. J., Shiao, M. S., Tsai, C. S., Lin, S. J. & Chen, Y. L., 一月 15 2011, 於 : Journal of the Science of Food and Agriculture. 91, 1, p. 134-141 8 p.

研究成果: 雜誌貢獻文章

45 引文 斯高帕斯(Scopus)
2010

Cobra CRISP functions as an inflammatory modulator via a novel Zn 2+- and heparan sulfate-dependent transcriptional regulation of endothelial cell adhesion molecules

Wang, Y. L., Kuo, J. H., Lee, S. C., Liu, J. S., Hsieh, Y. C., Shih, Y. T., Chen, C. J., Chiu, J. J. & Wu, W. G., 十一月 26 2010, 於 : Journal of Biological Chemistry. 285, 48, p. 37872-37883 12 p.

研究成果: 雜誌貢獻文章

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62 引文 斯高帕斯(Scopus)

Downregulation of signaling-active IGF-1 by dipeptidyl peptidase IV (DPP-IV)

Lin, C. T., Tang, H. Y., Han, Y. S., Liu, H. P., Huang, S. F., Chien, C. H., Shyy, J., Chiu, J. J. & Chen, X., 十二月 1 2010, 於 : International Journal of Biomedical Science. 6, 4, p. 301-309 9 p.

研究成果: 雜誌貢獻文章

8 引文 斯高帕斯(Scopus)

Estrogen augments shear stress-induced signaling and gene expression in osteoblast-like cells via estrogen receptor-mediated expression of β1-integrin

Yeh, C. R., Chiu, J. J., Lee, C. I., Lee, P. L., Shih, Y. T., Sun, J. S., Chien, S. & Cheng, C. K., 三月 2010, 於 : Journal of Bone and Mineral Research. 25, 3, p. 627-639 13 p.

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25 引文 斯高帕斯(Scopus)
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71 引文 斯高帕斯(Scopus)
2009

BMP-4 induction of arrest and differentiation of osteoblast-like cells via p21CIP1 and p27KIP1 regulation

Chang, S. F., Chang, T. K., Peng, H. H., Yeh, Y. T., Lee, D. Y., Yeh, C. R., Zhou, J., Cheng, C. K., Chang, C. A. & Chiu, J. J., 十一月 1 2009, 於 : Molecular Endocrinology. 23, 11, p. 1827-1838 12 p.

研究成果: 雜誌貢獻文章

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48 引文 斯高帕斯(Scopus)

Shear stress induces synthetic-to-contractile phenotypic modulation in smooth muscle cells via peroxisome proliferator-activated receptor α/δ activations by prostacyclin released by sheared endothelial cells

Tsai, M. C., Chen, L., Zhou, J., Tang, Z., Hsu, T. F., Wang, Y., Shih, Y. T., Peng, H. H., Wang, N., Guan, Y., Chien, S. & Chiu, J. J., 八月 28 2009, 於 : Circulation Research. 105, 5, p. 471-480 10 p.

研究成果: 雜誌貢獻文章

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65 引文 斯高帕斯(Scopus)

The effects of fiber size on MG63 cells cultured with collagen based matrices

Hsu, Y. M., Chen, C. N., Chiu, J. J., Chang, S. H. & Wang, Y. J., 十一月 1 2009, 於 : Journal of Biomedical Materials Research - Part B Applied Biomaterials. 91, 2, p. 737-745 9 p.

研究成果: 雜誌貢獻文章

21 引文 斯高帕斯(Scopus)
2008

Integrin-mediated expression of bone formation-related genes in osteoblast-like cells in response to fluid shear stress: Roles of extracellular matrix, Shc, and mitogen-activated protein kinase

Lee, D. Y., Yeh, C. R., Chang, S. F., Lee, P. L., Chien, S., Cheng, C. K. & Chiu, J. J., 七月 1 2008, 於 : Journal of Bone and Mineral Research. 23, 7, p. 1140-1149 10 p.

研究成果: 雜誌貢獻文章

64 引文 斯高帕斯(Scopus)

Synergism of biochemical and mechanical stimuli in the differentiation of human placenta-derived multipotent cells into endothelial cells

Wu, C. C., Chao, Y. C., Chen, C. N., Chien, S., Chen, Y. C., Chien, C. C., Chiu, J. J. & Linju Yen, B., 一月 10 2008, 於 : Journal of Biomechanics. 41, 4, p. 813-821 9 p.

研究成果: 雜誌貢獻文章

78 引文 斯高帕斯(Scopus)

Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad

Chang, S. F., Chang, C. A., Lee, D. Y., Lee, P. L., Yeh, Y. M., Yeh, C. R., Cheng, K., Chien, S. & Chiu, J. J., 三月 25 2008, 於 : Proceedings of the National Academy of Sciences of the United States of America. 105, 10, p. 3927-3932 6 p.

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115 引文 斯高帕斯(Scopus)
2007

Cell migration on nanophase-separated poly(carbonate urethane)s

Hsu, S. H., Chen, C. A., Chao, C. N., Chen, C. H. & Chiu, J. J., 三月 1 2007, 於 : Journal of Medical and Biological Engineering. 27, 1, p. 15-21 7 p.

研究成果: 雜誌貢獻文章

8 引文 斯高帕斯(Scopus)

Cell migration rate on poly(ε-caprolactone)/poly(ethylene glycol) diblock copolymers and correlation with the material sliding angle

Hsu, S. H., Tang, C. M., Chiu, J. J., Liao, T. C., Lin, C. C. & Iwata, H., 四月 10 2007, 於 : Macromolecular Bioscience. 7, 4, p. 482-490 9 p.

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12 引文 斯高帕斯(Scopus)

Directional shear flow and Rho activation prevent the endothelial cell apoptosis induced by micropatterned anisotropic geometry

Wu, C. C., Li, Y. S., Haga, J. H., Kaunas, R., Chiu, J. J., Su, F. C., Usami, S. & Chien, S., 一月 23 2007, 於 : Proceedings of the National Academy of Sciences of the United States of America. 104, 4, p. 1254-1259 6 p.

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66 引文 斯高帕斯(Scopus)

Mechanisms of induction of endothelial cell E-selectin expression by smooth muscle cells and its inhibition by shear stress

Chiu, J. J., Chen, L. J., Lee, C. I., Lee, P. L., Lee, D. Y., Tsai, M. C., Lin, C. W., Usami, S. & Chien, S., 七月 15 2007, 於 : Blood. 110, 2, p. 519-528 10 p.

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49 引文 斯高帕斯(Scopus)

The inhibition of TNF-α-induced E-selectin expression in endothelial cells via the JNK/NF-κB pathways by highly N-acetylated chitooligosaccharides

Lin, C. W., Chen, L. J., Lee, P. L., Lee, C. I., Lin, J. C. & Chiu, J. J., 三月 1 2007, 於 : Biomaterials. 28, 7, p. 1355-1366 12 p.

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34 引文 斯高帕斯(Scopus)
2006

Leukocyte-endothelium interaction: Measurement by laser tweezers force spectroscopy

Wang, S. K., Chiu, J. J., Lee, M. R., Chou, S. C., Chen, L. J. & Hwang, N. H. C., 九月 1 2006, 於 : Cardiovascular Engineering. 6, 3, p. 111-117 7 p.

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5 引文 斯高帕斯(Scopus)

N-acetylated chitooligosaccharides inhibit TNF-α-induced E-selectin expression in endothelial cells via the JNK-NF-κB pathways

Lin, C. W., Chen, L. J., Lee, C. I., Lee, P. L. & Chiu, J. J., 十二月 1 2006, 於 : MCB Molecular and Cellular Biomechanics. 3, 4, p. 165-166 2 p.

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Neutrophils, lymphocytes, and monocytes exhibit diverse behaviors in transendothelial and subendothelial migrations under coculture with smooth muscle cells in disturbed flow

Chen, C. N., Chang, S. F., Lee, P. L., Chang, K., Chen, L. J., Usami, S., Chien, S. & Chiu, J. J., 三月 1 2006, 於 : Blood. 107, 5, p. 1933-1942 10 p.

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58 引文 斯高帕斯(Scopus)
73 引文 斯高帕斯(Scopus)