• 4630 引文
  • 35 h-指數
1992 …2020

每年研究成果

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研究成果

Activation of PPAR-α induces cell cycle arrest and inhibits transforming growth factor-β1 induction of smooth muscle cell phenotype in 10T1/2 mesenchymal cells

Lien, S. C., Wei, S. Y., Chang, S. F., Chang, M. D. T., Chang, J. Y. & Chiu, J. J., 五月 1 2013, 於 : Cellular Signalling. 25, 5, p. 1252-1263 12 p.

研究成果: 雜誌貢獻文章

11 引文 斯高帕斯(Scopus)

A model for studying the effect of shear stress on interactions between vascular endothelial cells and smooth muscle cells

Chiu, J. J., Chen, L. J., Chen, C. N., Lee, P. L. & Lee, C. I., 四月 1 2004, 於 : Journal of Biomechanics. 37, 4, p. 531-539 9 p.

研究成果: 雜誌貢獻文章

94 引文 斯高帕斯(Scopus)

Analysis of the effect of disturbed flow on monocytic adhesion to endothelial cells

Chiu, J. J., Chen, C. N., Lee, P. L., Yang, C. T., Chuang, H. S., Chien, S. & Usami, S., 十二月 2003, 於 : Journal of Biomechanics. 36, 12, p. 1883-1895 13 p.

研究成果: 雜誌貢獻文章

78 引文 斯高帕斯(Scopus)

A numerical simulation of intimal thickening under shear in arteries

Lee, D. & Chiu, J. J., 一月 1 1992, 於 : Biorheology. 29, 2-3, p. 337-351 15 p.

研究成果: 雜誌貢獻文章

7 引文 斯高帕斯(Scopus)

Atherosclerosis and flow: Roles of epigenetic modulation in vascular endothelium

Lee, D. Y. & Chiu, J. J., 八月 7 2019, 於 : Journal of Biomedical Science. 26, 1, 56.

研究成果: 雜誌貢獻回顧型文獻

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12 引文 斯高帕斯(Scopus)

BMP-4 induction of arrest and differentiation of osteoblast-like cells via p21CIP1 and p27KIP1 regulation

Chang, S. F., Chang, T. K., Peng, H. H., Yeh, Y. T., Lee, D. Y., Yeh, C. R., Zhou, J., Cheng, C. K., Chang, C. A. & Chiu, J. J., 十一月 1 2009, 於 : Molecular Endocrinology. 23, 11, p. 1827-1838 12 p.

研究成果: 雜誌貢獻文章

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49 引文 斯高帕斯(Scopus)

BMP receptor-integrin interaction mediates responses of vascular endothelial Smad1/5 and proliferation to disturbed flow

Zhou, J., Lee, P. L., Lee, C. I., Wei, S. Y., Lim, S. H., Lin, T. E., Chien, S. & Chiu, J. J., 四月 1 2013, 於 : Journal of Thrombosis and Haemostasis. 11, 4, p. 741-755 15 p.

研究成果: 雜誌貢獻文章

33 引文 斯高帕斯(Scopus)

CBAP Functions as a Novel Component in Chemokine-Induced ZAP70-Mediated T-Cell Adhesion and Migration

Chiang, Y. J., Ho, K. C., Sun, C. T., Chiu, J. J., Lee, F. J., Liao, F., Yang-Yen, H. F. & Yen, J. J. Y., 四月 19 2013, 於 : PLoS ONE. 8, 4, e61761.

研究成果: 雜誌貢獻文章

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6 引文 斯高帕斯(Scopus)

Cell migration on nanophase-separated poly(carbonate urethane)s

Hsu, S. H., Chen, C. A., Chao, C. N., Chen, C. H. & Chiu, J. J., 三月 1 2007, 於 : Journal of Medical and Biological Engineering. 27, 1, p. 15-21 7 p.

研究成果: 雜誌貢獻文章

8 引文 斯高帕斯(Scopus)

Cell migration rate on poly(ε-caprolactone)/poly(ethylene glycol) diblock copolymers and correlation with the material sliding angle

Hsu, S. H., Tang, C. M., Chiu, J. J., Liao, T. C., Lin, C. C. & Iwata, H., 四月 10 2007, 於 : Macromolecular Bioscience. 7, 4, p. 482-490 9 p.

研究成果: 雜誌貢獻文章

12 引文 斯高帕斯(Scopus)

Cobra CRISP functions as an inflammatory modulator via a novel Zn 2+- and heparan sulfate-dependent transcriptional regulation of endothelial cell adhesion molecules

Wang, Y. L., Kuo, J. H., Lee, S. C., Liu, J. S., Hsieh, Y. C., Shih, Y. T., Chen, C. J., Chiu, J. J. & Wu, W. G., 十一月 26 2010, 於 : Journal of Biological Chemistry. 285, 48, p. 37872-37883 12 p.

研究成果: 雜誌貢獻文章

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62 引文 斯高帕斯(Scopus)
1 引文 斯高帕斯(Scopus)

Computation of physiological bifurcation flows using a patched grid

Lee, D. & Chiu, J. J., 十月 1992, 於 : Computers and Fluids. 21, 4, p. 519-535 17 p.

研究成果: 雜誌貢獻文章

14 引文 斯高帕斯(Scopus)

Convergence of physical and chemical signaling in the modulation of vascular smooth muscle cell cycle and proliferation by fibrillar collagen-regulated P66Shc

Yeh, Y. T., Lee, C. I., Lim, S. H., Chen, L. J., Wang, W. L., Chuang, Y. J. & Chiu, J. J., 十月 1 2012, 於 : Biomaterials. 33, 28, p. 6728-6738 11 p.

研究成果: 雜誌貢獻文章

5 引文 斯高帕斯(Scopus)
17 引文 斯高帕斯(Scopus)

Differential regulations of fibronectin and laminin in Smad2 activation in vascular endothelial cells in response to disturbed flow

Yang, T. L., Lee, P. L., Lee, D. Y., Wang, W. L., Wei, S. Y., Lee, C. I. & Chiu, J. J., 一月 2 2018, 於 : Journal of Biomedical Science. 25, 1, 1.

研究成果: 雜誌貢獻文章

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4 引文 斯高帕斯(Scopus)
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14 引文 斯高帕斯(Scopus)

Directional shear flow and Rho activation prevent the endothelial cell apoptosis induced by micropatterned anisotropic geometry

Wu, C. C., Li, Y. S., Haga, J. H., Kaunas, R., Chiu, J. J., Su, F. C., Usami, S. & Chien, S., 一月 23 2007, 於 : Proceedings of the National Academy of Sciences of the United States of America. 104, 4, p. 1254-1259 6 p.

研究成果: 雜誌貢獻文章

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66 引文 斯高帕斯(Scopus)

Downregulation of signaling-active IGF-1 by dipeptidyl peptidase IV (DPP-IV)

Lin, C. T., Tang, H. Y., Han, Y. S., Liu, H. P., Huang, S. F., Chien, C. H., Shyy, J., Chiu, J. J. & Chen, X., 十二月 1 2010, 於 : International Journal of Biomedical Science. 6, 4, p. 301-309 9 p.

研究成果: 雜誌貢獻文章

8 引文 斯高帕斯(Scopus)

Effects of disturbed flow on endothelial cells

Chiu, J. J., Wang, D. L., Usami, S., Chien, S. & Skalak, R., 二月 1998, 於 : Journal of Biomechanical Engineering. 120, 1, p. 2-8 7 p.

研究成果: 雜誌貢獻文章

178 引文 斯高帕斯(Scopus)

Effects of disturbed flow on leukocyte-endothelial cell adhesion

Chiu, J. J., Wang, D. L., Chien, S. & Usami, S., 十二月 1 1996, 於 : FASEB Journal. 10, 3, p. A25

研究成果: 雜誌貢獻文章

Effects of disturbed flow on vascular endothelium: Pathophysiological basis and clinical perspectives

Chiu, J. J. & Chien, S., 一月 1 2011, 於 : Physiological Reviews. 91, 1, p. 327-387 61 p.

研究成果: 雜誌貢獻回顧型文獻

1032 引文 斯高帕斯(Scopus)

Endothelial exposure to hypoxia induces Egr-1 expression involving PKCα-mediated Ras/Raf-1/ERK1/2 pathway

Lo, L. W., Cheng, J. J., Chiu, J. J., Wung, B. S., Liu, Y. C. & Wang, D. L., 一月 1 2001, 於 : Journal of Cellular Physiology. 188, 3, p. 304-312 9 p.

研究成果: 雜誌貢獻文章

86 引文 斯高帕斯(Scopus)

Endothelial progenitors promote hepatocarcinoma intrahepatic metastasis through monocyte chemotactic protein-1 induction of microRNA-21

Shih, Y. T., Wang, M. C., Zhou, J., Peng, H. H., Lee, D. Y. & Chiu, J. J., 七月 1 2015, 於 : Gut. 64, 7, p. 1132-1147 16 p.

研究成果: 雜誌貢獻文章

21 引文 斯高帕斯(Scopus)

Epigenetic regulation of vascular endothelial biology/pathobiology and response to fluid shear stress

Zhou, J., Lim, S. H. & Chiu, J. J., 十二月 1 2011, 於 : Cellular and Molecular Bioengineering. 4, 4, p. 560-578 19 p.

研究成果: 雜誌貢獻回顧型文獻

4 引文 斯高帕斯(Scopus)

Estrogen augments shear stress-induced signaling and gene expression in osteoblast-like cells via estrogen receptor-mediated expression of β1-integrin

Yeh, C. R., Chiu, J. J., Lee, C. I., Lee, P. L., Shih, Y. T., Sun, J. S., Chien, S. & Cheng, C. K., 三月 2010, 於 : Journal of Bone and Mineral Research. 25, 3, p. 627-639 13 p.

研究成果: 雜誌貢獻文章

25 引文 斯高帕斯(Scopus)

Focal TLR4 activation mediates disturbed flow-induced endothelial inflammation

Qu, D., Wang, L., Huo, M., Song, W., Lau, C. W., Xu, J., Xu, A., Yao, X., Chiu, J. J., Tian, X. Y. & Huang, Y., 一月 1 2020, 於 : Cardiovascular Research. 116, 1, p. 226-236 11 p.

研究成果: 雜誌貢獻文章

8 引文 斯高帕斯(Scopus)

Force-specific activation of Smad1/5 regulates vascular endothelial cell cycle progression in response to disturbed flow

Zhou, J., Lee, P. L., Tsai, C. S., Lee, C. I., Yang, T. L., Chuang, H. S., Lin, W. W., Lin, T. E., Lim, S. H., Wei, S. Y., Chen, Y. L., Chien, S. & Chiu, J. J., 五月 15 2012, 於 : Proceedings of the National Academy of Sciences of the United States of America. 109, 20, p. 7770-7775 6 p.

研究成果: 雜誌貢獻文章

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51 引文 斯高帕斯(Scopus)

Hemodynamics-Based Strategy of Using Retinoic Acid Receptor and Retinoid X Receptor Agonists to Induce MicroRNA-10a and Inhibit Atherosclerotic Lesion

Lee, D. Y. & Chiu, J. J., 一月 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 143-169 27 p. (Methods in Molecular Biology; 卷 2019).

研究成果: 書貢獻/報告類型章節

Increase of reactive oxygen species (ROS) in Endothelial cells by shear flow and involvement of ROS in shear-induced c-fos expression

Hsieh, H. J., Cheng, C. C., Wu, S. T. A., Chiu, J. J., Wung, B. S. & Wang, D. L., 五月 1 1998, 於 : Journal of Cellular Physiology. 175, 2, p. 156-162 7 p.

研究成果: 雜誌貢獻文章

152 引文 斯高帕斯(Scopus)

Induction of microRNA-10a using retinoic acid receptor-α and retinoid x receptor-α agonists inhibits atherosclerotic lesion formation

Lee, D. Y., Yang, T. L., Huang, Y. H., Lee, C. I., Chen, L. J., Shih, Y. T., Wei, S. Y., Wang, W. L., Wu, C. C. & Chiu, J. J., 四月 2018, 於 : Atherosclerosis. 271, p. 36-44 9 p.

研究成果: 雜誌貢獻文章

10 引文 斯高帕斯(Scopus)

Inhibition of miR-21 alleviated cardiac perivascular fibrosis via repressing EndMT in T1DM

Li, Q., Yao, Y., Shi, S., Zhou, M., Zhou, Y., Wang, M., Chiu, J. J., Huang, Z., Zhang, W., Liu, M., Wang, Q. & Tu, X., 一月 1 2020, 於 : Journal of Cellular and Molecular Medicine. 24, 1, p. 910-920 11 p.

研究成果: 雜誌貢獻文章

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3 引文 斯高帕斯(Scopus)

Integrin-mediated expression of bone formation-related genes in osteoblast-like cells in response to fluid shear stress: Roles of extracellular matrix, Shc, and mitogen-activated protein kinase

Lee, D. Y., Yeh, C. R., Chang, S. F., Lee, P. L., Chien, S., Cheng, C. K. & Chiu, J. J., 七月 1 2008, 於 : Journal of Bone and Mineral Research. 23, 7, p. 1140-1149 10 p.

研究成果: 雜誌貢獻文章

64 引文 斯高帕斯(Scopus)

Integrin-YAP/TAZ-JNK cascade mediates atheroprotective effect of unidirectional shear flow

Huang, Y., Wang, L., Luo, J. Y., Li, B., Tian, X. Y., Chen, L. J., Huang, Y., Liu, J., Deng, D., Lau, C. W., Wan, S., Ai, DI., Mak, K. L. K., Tong, K. K., Kwan, K. M., Wang, N., Chiu, J. J. & Zhu, Y., 十二月 22 2016, 於 : Nature. 540, 7634, p. 579-582 4 p.

研究成果: 雜誌貢獻文章

150 引文 斯高帕斯(Scopus)

Intimal thickening under shear in a carotid bifurcation - A numerical study

Lee, D. & Chiu, J. J., 一月 1996, 於 : Journal of Biomechanics. 29, 1, p. 1-11 11 p.

研究成果: 雜誌貢獻文章

33 引文 斯高帕斯(Scopus)

Leukocyte-endothelium interaction: Measurement by laser tweezers force spectroscopy

Wang, S. K., Chiu, J. J., Lee, M. R., Chou, S. C., Chen, L. J. & Hwang, N. H. C., 九月 1 2006, 於 : Cardiovascular Engineering. 6, 3, p. 111-117 7 p.

研究成果: 雜誌貢獻文章

5 引文 斯高帕斯(Scopus)

Matrix stiffness determines the phenotype of vascular smooth muscle cell in vitro and in vivo: Role of DNA methyltransferase 1

Xie, S. A., Zhang, T., Wang, J., Zhao, F., Zhang, Y. P., Yao, W. J., Hur, S. S., Yeh, Y. T., Pang, W., Zheng, L. S., Fan, Y. B., Kong, W., Wang, X., Chiu, J. J. & Zhou, J., 二月 2018, 於 : Biomaterials. 155, p. 203-216 14 p.

研究成果: 雜誌貢獻文章

23 引文 斯高帕斯(Scopus)

Matrix Stiffness Regulates Endothelial Cell Proliferation through Septin 9

Yeh, Y. T., Hur, S. S., Chang, J., Wang, K. C., Chiu, J. J., Li, Y. S. & Chien, S., 十月 31 2012, 於 : PLoS ONE. 7, 10, e46889.

研究成果: 雜誌貢獻文章

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65 引文 斯高帕斯(Scopus)

Mechanical regulation of cancer cell apoptosis and autophagy: Roles of bone morphogenetic protein receptor, Smad1/5, and p38 MAPK

Lien, S. C., Chang, S. F., Lee, P. L., Wei, S. Y., Chang, M. D. T., Chang, J. Y. & Chiu, J. J., 十二月 1 2013, 於 : Biochimica et Biophysica Acta - Molecular Cell Research. 1833, 12, p. 3124-3133 10 p.

研究成果: 雜誌貢獻文章

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55 引文 斯高帕斯(Scopus)

Mechanical regulation of epigenetics in vascular biology and pathobiology

Chen, L. J., Wei, S. Y. & Chiu, J. J., 四月 1 2013, 於 : Journal of Cellular and Molecular Medicine. 17, 4, p. 437-448 12 p.

研究成果: 雜誌貢獻文章

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46 引文 斯高帕斯(Scopus)

Mechanisms of induction of endothelial cell E-selectin expression by smooth muscle cells and its inhibition by shear stress

Chiu, J. J., Chen, L. J., Lee, C. I., Lee, P. L., Lee, D. Y., Tsai, M. C., Lin, C. W., Usami, S. & Chien, S., 七月 15 2007, 於 : Blood. 110, 2, p. 519-528 10 p.

研究成果: 雜誌貢獻文章

49 引文 斯高帕斯(Scopus)

MicroRNA-10a is crucial for endothelial response to different flow patterns via interaction of retinoid acid receptors and histone deacetylases

Lee, D. Y., Lin, T. E., Lee, C. I., Zhou, J., Huang, Y. H., Lee, P. L., Shih, Y. T., Chien, S. & Chiu, J. J., 二月 21 2017, 於 : Proceedings of the National Academy of Sciences of the United States of America. 114, 8, p. 2072-2077 6 p.

研究成果: 雜誌貢獻文章

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20 引文 斯高帕斯(Scopus)

MicroRNA-21 and venous neointimal hyperplasia of dialysis vascular access

Wu, C. C., Chen, L. J., Hsieh, M. Y., Lo, C. M., Lin, M. H., Tsai, H. E., Song, H. L. & Chiu, J. J., 一月 1 2018, 於 : Clinical Journal of the American Society of Nephrology. 13, 11, p. 1712-1720 9 p.

研究成果: 雜誌貢獻文章

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3 引文 斯高帕斯(Scopus)

MicroRNA-21 targets peroxisome proliferators-activated receptor-α in an autoregulatory loop to modulate flow-induced endothelial inflammation

Zhou, J., Wang, K. C., Wu, W., Subramaniam, S., Shyy, J. Y. J., Chiu, J. J., Li, J. Y. S. & Chien, S., 六月 21 2011, 於 : Proceedings of the National Academy of Sciences of the United States of America. 108, 25, p. 10355-10360 6 p.

研究成果: 雜誌貢獻文章

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241 引文 斯高帕斯(Scopus)

MicroRNA mediation of endothelial inflammatory response to smooth muscle cells and its inhibition by atheroprotective shear stress

Chen, L. J., Chuang, L., Huang, Y. H., Zhou, J., Lim, S. H., Lee, C. I., Lin, W. W., Lin, T. E., Wang, W. L., Chen, L., Chien, S. & Chiu, J. J., 三月 27 2015, 於 : Circulation Research. 116, 7, p. 1157-1169 13 p.

研究成果: 雜誌貢獻文章

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30 引文 斯高帕斯(Scopus)

Modulation of chemotactic and pro-inflammatory activities of endothelial progenitor cells by hepatocellular carcinoma

Shih, Y. T., Wang, M. C., Peng, H. H., Chen, T. F., Chen, L., Chang, J. Y. & Chiu, J. J., 三月 1 2012, 於 : Cellular Signalling. 24, 3, p. 779-793 15 p.

研究成果: 雜誌貢獻文章

15 引文 斯高帕斯(Scopus)

N-acetylated chitooligosaccharides inhibit TNF-α-induced E-selectin expression in endothelial cells via the JNK-NF-κB pathways

Lin, C. W., Chen, L. J., Lee, C. I., Lee, P. L. & Chiu, J. J., 十二月 1 2006, 於 : MCB Molecular and Cellular Biomechanics. 3, 4, p. 165-166 2 p.

研究成果: 雜誌貢獻文章

Neutrophils, lymphocytes, and monocytes exhibit diverse behaviors in transendothelial and subendothelial migrations under coculture with smooth muscle cells in disturbed flow

Chen, C. N., Chang, S. F., Lee, P. L., Chang, K., Chen, L. J., Usami, S., Chien, S. & Chiu, J. J., 三月 1 2006, 於 : Blood. 107, 5, p. 1933-1942 10 p.

研究成果: 雜誌貢獻文章

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58 引文 斯高帕斯(Scopus)