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研究成果 1988 2019

  • 924 引文
  • 17 h-指數
  • 50 文章
  • 1 會議貢獻
篩選
文章
2019

BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine

Chao, P. K., Chang, H. F., Chang, W. T., Yeh, T. K., Ou, L. C., Chuang, J. Y., Tsu-An Hsu, J., Tao, P. L., Loh, H. H., Shih, C., Ueng, S. H. & Yeh, S. H., 一月 1 2019, 於 : Neuropharmacology. 107678.

研究成果: 雜誌貢獻文章

Peptide Receptors
mu Opioid Receptor
Morphine
Naloxone
Arrestin
開啟存取
CCAAT-Enhancer-Binding Protein-delta
Platelet-Derived Growth Factor
Glioma
Stem Cells
Interleukin-1

Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice

Chao, P. K., Chang, H. F., Ou, L. C., Chuang, J. Y., Lee, P. T., Chang, W. T., Chen, S. C., Ueng, S. H., Hsu, J. T. A., Tao, P. L., Law, P. Y., Loh, H. H. & Yeh, S. H., 十二月 1 2019, 於 : Scientific Reports. 9, 1, 2405.

研究成果: 雜誌貢獻文章

mu Opioid Receptor
Endocytosis
Morphine
Ligands
Morphine Dependence
temozolomide
Dehydroepiandrosterone
Glioblastoma
Acetylation
Phosphorylation

Sp1 in Astrocyte Is Important for Neurite Outgrowth and Synaptogenesis

Hung, C. Y., Hsu, T. I., Chuang, J. Y., Su, T. P., Chang, W. C. & Hung, J. J., 一月 1 2019, 於 : Molecular Neurobiology.

研究成果: 雜誌貢獻文章

Astrocytes
Synapses
Hippocampus
Neurons
Toll-Like Receptor 2
2018
1 引文 (Scopus)

Ephexin1 is required for Eph-Mediated limb trajectory of spinal motor axons

Chang, C. J., Chang, M. Y., Chou, S. Y., Huang, C. C., Chuang, J. Y., Hsu, T. I., Chang, H. F., Wu, Y. H., Wu, C. C., Morales, D., Kania, A. & Kao, T. J., 二月 21 2018, 於 : Journal of Neuroscience. 38, 8, p. 2043-2056 14 p.

研究成果: 雜誌貢獻文章

Axons
Extremities
Ephrins
Growth Cones
Motor Neurons
5 引文 (Scopus)
temozolomide
Autophagy
Glioma
Apoptosis
Pharmaceutical Preparations
5 引文 (Scopus)
Ubiquitination
Glioma
Glioblastoma
Stem Cells
temozolomide

Nck2 is essential for limb trajectory selection by spinal motor axons

Chang, C. J., Chang, M. Y., Lee, Y. C., Chen, K. Y., Hsu, T. I., Wu, Y. H., Chuang, J. Y. & Kao, T. J., 九月 1 2018, 於 : Developmental Dynamics. 247, 9, p. 1043-1056 14 p.

研究成果: 雜誌貢獻文章

Axons
Extremities
Motor Neurons
Ephrins
Neurites
4 引文 (Scopus)
Glioblastoma
Amyloid
Integrins
Serum
Glioma
1 引文 (Scopus)

Upregulation of Znf179 acetylation by SAHA protects cells against oxidative stress

Wu, C. C., Lee, P. T., Kao, T. J., Chou, S. Y., Su, R. Y., Lee, Y. C., Yeh, S. H., Liou, J. P., Hsu, T. I., Su, T. P., Chuang, C. K., Chang, W. C. & Chuang, J. Y., 十月 1 2018, 於 : Redox Biology. 19, p. 74-80 7 p.

研究成果: 雜誌貢獻文章

Acetylation
Oxidative stress
Zinc Fingers
Zinc
Oxidative Stress
2017
3 引文 (Scopus)

1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4 H -indazol-4-one: A Novel Opioid Receptor Agonist with Less Accompanying Gastrointestinal Dysfunction than Morphine

Chao, P. K., Ueng, S. H., Ou, L. C., Yeh, T. K., Chang, W. T., Chang, H. F., Chen, S. C., Tao, P. L., Law, P. Y., Loh, H. H., Cheng, M. F., Chuang, J. Y., Chen, C. T., Shih, C. & Yeh, S. H., 五月 1 2017, 於 : Anesthesiology. 126, 5, p. 952-966 15 p.

研究成果: 雜誌貢獻文章

Opioid Receptors
Morphine
Opioid Analgesics
Charcoal
Surgical Instruments
2 引文 (Scopus)

Mapping the naloxone binding sites on the mu-opioid receptor using cell-based photocrosslinkers

Ke, Y. Y., Huang, Y. H., Chien, W. C., Loh, H. H., Chuang, J. Y. & Yeh, S. H., 三月 1 2017, 於 : Biochimica et Biophysica Acta - Proteins and Proteomics. 1865, 3, p. 336-343 8 p.

研究成果: 雜誌貢獻文章

mu Opioid Receptor
Naloxone
Binding Sites
Morphine
Amber
1 引文 (Scopus)

Nm23-H1-stabilized hnRNPA2/B1 promotes internal ribosomal entry site (IRES)-mediated translation of Sp1 in the lung cancer progression

Hung, C. Y., Wang, Y. C., Chuang, J. Y., Young, M. J., Liaw, H., Chang, W. C. & Hung, J. J., 十二月 1 2017, 於 : Scientific Reports. 7, 1, 9166.

研究成果: 雜誌貢獻文章

Protein Biosynthesis
Lung Neoplasms
Proteins
Messenger RNA
Protein Stability
5 引文 (Scopus)

Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O6-methylguanine-DNA methyltransferase

Chang, K. Y., Hsu, T. I., Hsu, C. C., Tsai, S. Y., Liu, J. J., Chou, S. W., Liu, M. S., Liou, J. P., Ko, C. Y., Chen, K. Y., Hung, J. J., Chang, W. C., Chuang, C. K., Kao, T. J. & Chuang, J. Y., 十月 1 2017, 於 : Redox Biology. 13, p. 655-664 10 p.

研究成果: 雜誌貢獻文章

temozolomide
Methyltransferases
Glioblastoma
DNA
Proteins
13 引文 (Scopus)

Specificity protein 1-zinc finger protein 179 pathway is involved in the attenuation of oxidative stress following brain injury

Chuang, J-Y., Kao, T-J., Lin, S. H., Wu, A. C., Lee, P. T., Su, T. P., Yeh, S. H., Lee, Y-C., Wu, C-C. & Chang, W-C., 四月 1 2017, 於 : Redox Biology. 11, p. 135-143 9 p.

研究成果: 雜誌貢獻文章

Oxidative stress
Zinc Fingers
Brain Injuries
Zinc
Brain
2 引文 (Scopus)

Stress stimuli induce cancer-stemness gene expression via Sp1 activation leading to therapeutic resistance in glioblastoma

Chang, K. Y., Huang, C. T., Hsu, T. I., Hsu, C. C., Liu, J. J., Chuang, C. K., Hung, J. J., Chang, W. C., Tsai, K. K. & Chuang, J. Y., 十一月 4 2017, 於 : Biochemical and Biophysical Research Communications. 493, 1, p. 14-19 6 p.

研究成果: 雜誌貢獻文章

Neoplasm Genes
Glioblastoma
Gene expression
Chemical activation
temozolomide
temozolomide
Dehydroepiandrosterone
Glioma
Cytochrome P-450 Enzyme System
Up-Regulation
2016
7 引文 (Scopus)

Suberoylanilide hydroxamic acid represses glioma stem-like cells

Hsu, C. C., Chang, W-C., Hsu, T-I., Liu, J. J., Yeh, S. H., Wang, J-Y., Liou, J-P., Ko, C-Y., Chang, K. Y. & Chuang, J-Y., 十一月 18 2016, 於 : Journal of Biomedical Science. 23, 1, p. 1-12 12 p.

研究成果: 雜誌貢獻文章

Glioma
Stem Cells
Glioblastoma
Cells
Histone Deacetylases
9 引文 (Scopus)

The sigma-1 receptor-zinc finger protein 179 pathway protects against hydrogen peroxide-induced cell injury

Su, T. C., Lin, S. H., Lee, P. T., Yeh, S. H., Hsieh, T. H., Chou, S. Y., Su, T. P., Hung, J. J., Chang, W. C., Lee, Y. C. & Chuang, J. Y., 六月 1 2016, 於 : Neuropharmacology. 105, p. 1-9 9 p.

研究成果: 雜誌貢獻文章

Zinc Fingers
Hydrogen Peroxide
Reactive Oxygen Species
Wounds and Injuries
Dehydroepiandrosterone Sulfate
2015
45 引文 (Scopus)
Chromatin Assembly and Disassembly
Nuclear Envelope
Cocaine
Monoamine Oxidase
Endoplasmic Reticulum
2014
13 引文 (Scopus)

Morphine drives internal ribosome entry site-mediated hnRNP K translation in neurons through opioid receptor-dependent signaling

Lee, P. T., Chao, P. K., Ou, L. C., Chuang, J. Y., Lin, Y. C., Chen, S. C., Chang, H. F., Law, P. Y., Loh, H. H., Chao, Y. S., Su, T. P. & Yeh, S. H., 十二月 1 2014, 於 : Nucleic Acids Research. 42, 21, p. 13012-13025 14 p.

研究成果: 雜誌貢獻文章

Heterogeneous-Nuclear Ribonucleoprotein K
Opioid Receptors
Morphine
Neurons
mu Opioid Receptor
17 引文 (Scopus)
Proteolysis
Lung Neoplasms
Carcinogenesis
Phosphorylation
Acetylation
9 引文 (Scopus)

Pin1-mediated Sp1 phosphorylation by CDK1 increases Sp1 stability and decreases its DNA-binding activity during mitosis

Yang, H. C., Chuang, J. Y., Jeng, W. Y., Liu, C. I., Wang, A. H. J., Lu, P. J., Chang, W. C. & Hung, J. J., 十二月 16 2014, 於 : Nucleic Acids Research. 42, 22, p. 13573-13587 15 p.

研究成果: 雜誌貢獻文章

Mitosis
Phosphorylation
DNA
Peptides
Cell Cycle
17 引文 (Scopus)

Roles of testosterone and amygdaloid LTP induction in determining sex differences in fear memory magnitude

Chen, L. S., Tzeng, W. Y., Chuang, J. Y., Cherng, C. G., Gean, P. W. & Yu, L., 2014, 於 : Hormones and Behavior. 66, 3, p. 498-508 11 p.

研究成果: 雜誌貢獻文章

Long-Term Potentiation
Sex Characteristics
Fear
Testosterone
Freezing
2013
21 引文 (Scopus)

Companions reverse stressor-induced decreases in neurogenesis and cocaine conditioning possibly by restoring BDNF and NGF levels in dentate gyrus

Tzeng, W. Y., Chuang, J. Y., Lin, L. C., Cherng, C. G., Lin, K. Y., Chen, L. H., Su, C. C. & Yu, L., 三月 2013, 於 : Psychoneuroendocrinology. 38, 3, p. 425-437 13 p.

研究成果: 雜誌貢獻文章

Brain-Derived Neurotrophic Factor
Neurogenesis
Dentate Gyrus
Nerve Growth Factor
Cocaine
16 引文 (Scopus)

D-cycloserine, sarcosine and D-serine diminish the expression of cocaine-induced conditioned place preference

Yang, F. Y., Lee, Y. S., Cherng, C. G., Cheng, L. Y., Chang, W. T., Chuang, J. Y., Kao, G. S. & Yu, L., 六月 2013, 於 : Journal of Psychopharmacology. 27, 6, p. 550-558 9 p.

研究成果: 雜誌貢獻文章

Sarcosine
Cycloserine
Cocaine
Serine
N-Methyl-D-Aspartate Receptors
110 引文 (Scopus)

Dynamic interaction between sigma-1 receptor and Kv1.2 shapes neuronal and behavioral responses to cocaine

Kourrich, S., Hayashi, T., Chuang, J. Y., Tsai, S. Y., Su, T. P. & Bonci, A., 一月 7 2013, 於 : Cell. 152, 1-2, p. 236-247 12 p.

研究成果: 雜誌貢獻文章

Cocaine
Kv1.2 Potassium Channel
Proteins
Drug-Seeking Behavior
Nucleus Accumbens
2012
8 引文 (Scopus)

Disruption of memory reconsolidation impairs storage of other, non-reactivated memory

Tzeng, W. Y., Chang, W. T., Chuang, J. Y., Lin, K. Y., Cherng, C. G. & Yu, L., 二月 2012, 於 : Neurobiology of Learning and Memory. 97, 2, p. 241-249 9 p.

研究成果: 雜誌貢獻文章

Amygdala
Lidocaine
Cocaine
Emotions
Basolateral Nuclear Complex
45 引文 (Scopus)

Interactions between amyloid-β and hemoglobin: Implications for amyloid plaque formation in alzheimer's disease

Chuang, J. Y., Lee, C. W., Shih, Y. H., Yang, T., Yu, L. & Kuo, Y. M., 三月 6 2012, 於 : PLoS One. 7, 3, e33120.

研究成果: 雜誌貢獻文章

Amyloid Plaques
amyloid
Alzheimer disease
Amyloid
hemoglobin
2 引文 (Scopus)

Involvement of amygdaloid protein synthesis in early- and late-phase reconsolidation of emotion-related memories

Chuang, J. Y., Lin, K. Y., Cherng, C. G. & Yu, L., 2012, 於 : Chinese Journal of Physiology. 55, 5, p. 1-9 9 p.

研究成果: 雜誌貢獻文章

Anisomycin
Cocaine
Emotions
Proteins
Amygdala
6 引文 (Scopus)

Odors from proximal species reverse the stress-decreased neurogenesis via main olfactory processing

Cherng, C. F. G., Chang, C. P., Su, C. C., Tzeng, W. Y., Chuang, J. Y., Chen, L. H., Lin, K. Y. & Yu, L., 四月 1 2012, 於 : Behavioural Brain Research. 229, 1, p. 106-112 7 p.

研究成果: 雜誌貢獻文章

Neurogenesis
Cell Proliferation
Dentate Gyrus
Odorants
Zinc Sulfate
23 引文 (Scopus)

Sp1 phosphorylation by cyclin-dependent kinase 1/cyclin B1 represses its DNA-binding activity during mitosis in cancer cells

Chuang, J. Y., Wang, S. A., Yang, W. B., Yang, H. C., Hung, C. Y., Su, T. P., Chang, W. C. & Hung, J. J., 十一月 22 2012, 於 : Oncogene. 31, 47, p. 4946-4959 14 p.

研究成果: 雜誌貢獻文章

CDC2 Protein Kinase
Cyclin B1
Mitosis
Phosphorylation
DNA
2011
1 引文 (Scopus)

Accumbal 14-3-3ζ protein downregulation is associated with cocaine-conditioned memory

Kao, G. S., Chuang, J. Y., Cherng, C. F. G. & Yu, L., 十二月 2011, 於 : NeuroSignals. 19, 4, p. 175-188 14 p.

研究成果: 雜誌貢獻文章

14-3-3 Proteins
Cocaine
Down-Regulation
Cues
Recurrence
21 引文 (Scopus)
Histone Deacetylase 1
Cyclin B1
Methylation
Hydrogen Peroxide
Cells
19 引文 (Scopus)

Overexpression of HDAC1 induces cellular senescence by Sp1/PP2A/pRb pathway

Chuang, J. Y. & Hung, J. J., 四月 15 2011, 於 : Biochemical and Biophysical Research Communications. 407, 3, p. 587-592 6 p.

研究成果: 雜誌貢獻文章

Protein Phosphatase 2
Cell Aging
Catalytic Domain
Histone Deacetylase 1
Cells
9 引文 (Scopus)

Repeated co-administrations of alcohol- and ethamphetamine-produced anxiogenic effect could be associated with the neurotoxicity in the dentate gyrus

Chuang, J. Y., Chang, W. T., Cherng, C. G., Kao, G. S. & Yu, L., 2011, 於 : Journal of Neural Transmission. 118, 11, p. 1559-1569 11 p.

研究成果: 雜誌貢獻文章

Dentate Gyrus
Alcohols
Lateral Ventricles
Amygdala
Prefrontal Cortex
2010
20 引文 (Scopus)

MCAF1 and synergistic activation of the transcription of Epstein-Barr virus lytic genes by Rta and Zta

Chang, L. K., Chuang, J. Y., Nakao, M. & Liu, S. T., 四月 10 2010, 於 : Nucleic Acids Research. 38, 14, p. 4687-4700 14 p., gkq243.

研究成果: 雜誌貢獻文章

Response Elements
Human Herpesvirus 4
Transcriptional Activation
Genes
Proteins
17 引文 (Scopus)

Presence of conspecifics and their odor-impregnated objects reverse stress-decreased neurogenesis in mouse dentate gyrus

Cherng, C. G., Lin, P. S., Chuang, J. Y., Chang, W. T., Lee, Y. S., Kao, G. S., Lai, Y. T. & Yu, L., 三月 2010, 於 : Journal of Neurochemistry. 112, 5, p. 1138-1146 9 p.

研究成果: 雜誌貢獻文章

Neurogenesis
Dentate Gyrus
Odors
Bromodeoxyuridine
Social Support
2009
13 引文 (Scopus)

Chronic treatment with monoamine oxidase-B inhibitors decreases cocaine reward in mice

Ho, M. C., Cherng, C. G., Tsai, Y. P. N., Chiang, C. Y., Chuang, J. Y., Kao, S. F. & Yu, L., 七月 2009, 於 : Psychopharmacology. 205, 1, p. 141-149 9 p.

研究成果: 雜誌貢獻文章

Clorgyline
Monoamine Oxidase Inhibitors
Monoamine Oxidase
Reward
Cocaine
30 引文 (Scopus)

Heat Shock Protein 90 Is Important for Sp1 Stability during Mitosis

Wang, S. A., Chuang, J. Y., Yeh, S. H., Wang, Y. T., Liu, Y. W., Chang, W. C. & Hung, J. J., 四月 17 2009, 於 : Journal of Molecular Biology. 387, 5, p. 1106-1119 14 p.

研究成果: 雜誌貢獻文章

Mitogen-Activated Protein Kinase 8
HSP90 Heat-Shock Proteins
Mitosis
Arachidonate 12-Lipoxygenase
Interphase
10 引文 (Scopus)

Medial prefrontal cortex and nucleus accumbens core are involved in retrieval of the methamphetamine-associated memory

Chiang, C. Y., Cherng, C. G., Lai, Y. T., Fan, H. Y., Chuang, J. Y., Kao, G. S., Chang, W. T. & Yu, L., 一月 30 2009, 於 : Behavioural Brain Research. 197, 1, p. 24-30 7 p.

研究成果: 雜誌貢獻文章

Methamphetamine
Nucleus Accumbens
Prefrontal Cortex
Cues
Neurons
56 引文 (Scopus)

Overexpression of Sp1 leads to p53-dependent apoptosis in cancer cells

Chuang, J. Y., Wu, C. H., Lai, M. D., Chang, W. C. & Hung, J. J., 十一月 1 2009, 於 : International Journal of Cancer. 125, 9, p. 2066-2076 11 p.

研究成果: 雜誌貢獻文章

Apoptosis
Neoplasms
Cell Line
Annexin A5
Product Packaging
2008
32 引文 (Scopus)

Enhancement of Transactivation Activity of Rta of Epstein-Barr Virus by RanBPM

Chang, L. K., Liu, S. T., Kuo, C. W., Wang, W. H., Chuang, J. Y., Bianchi, E. & Hong, Y. R., 五月 29 2008, 於 : Journal of Molecular Biology. 379, 2, p. 231-242 12 p.

研究成果: 雜誌貢獻文章

Human Herpesvirus 4
Transcriptional Activation
Immediate-Early Proteins
Sumoylation
Virus Activation
83 引文 (Scopus)

Phosphorylation by c-Jun NH2-terminal kinase 1 regulates the stability of transcription factor Sp1 during mitosis

Chuang, J. Y., Wang, Y. T., Yeh, S. H., Liu, Y. W., Chang, W. C. & Hung, J. J., 三月 2008, 於 : Molecular Biology of the Cell. 19, 3, p. 1139-1151 13 p.

研究成果: 雜誌貢獻文章

Sp1 Transcription Factor
JNK Mitogen-Activated Protein Kinases
Mitosis
Phosphorylation
Tumor Cell Line
63 引文 (Scopus)

Sumoylation of Specificity Protein 1 Augments Its Degradation by Changing the Localization and Increasing the Specificity Protein 1 Proteolytic Process

Wang, Y. T., Chuang, J. Y., Shen, M. R., Yang, W. B., Chang, W. C. & Hung, J. J., 七月 25 2008, 於 : Journal of Molecular Biology. 380, 5, p. 869-885 17 p.

研究成果: 雜誌貢獻文章

Sumoylation
SUMO-1 Protein
Proteins
Proteolysis
Ubiquitination
2006
18 引文 (Scopus)

Sumoylation of Rta of Epstein-Barr virus is preferentially enhanced by PIASxβ

Liu, S. T., Wang, W. H., Hong, Y. R., Chuang, J. Y., Lu, P. J. & Chang, L. K., 八月 2006, 於 : Virus Research. 119, 2, p. 163-170 8 p.

研究成果: 雜誌貢獻文章

Sumoylation
Human Herpesvirus 4
Immediate-Early Proteins
Ubiquitin-Protein Ligases
Response Elements
2005
51 引文 (Scopus)

Activation of Sp1-mediated transcription by Rta of Epstein-Barr virus via an interaction with MCAF1

Chang, L. K., Chung, J. Y., Hong, Y. R., Ichimura, T., Nakao, M. & Liu, S. T., 2005, 於 : Nucleic Acids Research. 33, 20, p. 6528-6539 12 p.

研究成果: 雜誌貢獻文章

Human Herpesvirus 4
Chromatin
Response Elements
Transcriptional Activation
snRNP Core Proteins
2003
75 引文 (Scopus)

Inhibition of Epstein-Barr virus lytic cycle by (-)-epigallocatechin gallate

Chang, L. K., Wei, T. T., Chiu, Y. F., Tung, C. P., Chuang, J. Y., Hung, S. K., Li, C. & Liu, S. T., 二月 21 2003, 於 : Biochemical and Biophysical Research Communications. 301, 4, p. 1062-1068 7 p.

研究成果: 雜誌貢獻文章

Human Herpesvirus 4
Viruses
Microarrays
Immediate-Early Genes
Flow cytometry
1988
16 引文 (Scopus)

Changes in T-cell subsets after radiation therapy

Yang, S., Rafla, S., Youssef, E., Selim, H., Salloum, N. & Chuang, J. Y., 一月 1 1988, 於 : Radiology. 168, 2, p. 537-540 4 p.

研究成果: 雜誌貢獻文章

T-Lymphocyte Subsets
Radiotherapy
Helper-Inducer T-Lymphocytes
Neoplasms
Head and Neck Neoplasms