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研究成果 2000 2019

  • 421 引文
  • 13 h-指數
  • 32 文章
篩選
文章
2019
2 引文 (Scopus)

Fluorine-Modified Rutaecarpine Exerts Cyclooxygenase-2 Inhibition and Anti-inflammatory Effects in Lungs

Lee, C., Liao, J., Chen, S., Yen, C., Lee, Y., Huang, S., Huang, S., Lin, C. M. & Chang, V. H., 2019, 於 : Frontiers in Pharmacology. 10, p. 91

研究成果: 雜誌貢獻文章

Fluorine
Cyclooxygenase 2
Anti-Inflammatory Agents
Lung
Myofibroblasts
2018
11 引文 (Scopus)
docetaxel
Lecithins
Drug Delivery Systems
Therapeutics
Neoplasms
Acupressure
Stem Cell Factor
Blood Cells
Drug Therapy
Hemoglobins

Therapeutic effect of repurposed temsirolimus in lung adenocarcinoma model

Chang, H. W., Wu, M. J., Lin, Z. M., Wang, C. Y., Cheng, S. Y., Lin, Y. K., Chow, Y. H., Ch'ang, H. J. & Chang, V. H. S., 七月 24 2018, 於 : Frontiers in Pharmacology. 9, JUL, p. 778 778.

研究成果: 雜誌貢獻文章

Therapeutic Uses
gemcitabine
Cisplatin
Lung Neoplasms
Neoplasms
2017
6 引文 (Scopus)

Analyzing polymeric matrix for fabrication of a biodegradable microneedle array to enhance transdermal delivery

Hwa, K. Y., Chang, V. H. S., Cheng, Y. Y., Wang, Y. D., Jan, P. S., Subramani, B., Wu, M. J. & Wang, B. K., 十二月 1 2017, 於 : Biomedical Microdevices. 19, 4, 84.

研究成果: 雜誌貢獻文章

Drug Delivery Systems
Polysaccharides
Digestive system
Fabrication
Vacuum deposition
4 引文 (Scopus)

Characterization of a transgenic mouse model exhibiting spontaneous lung adenocarcinomas with a metastatic phenotype

Chang, H. W., Lin, Z. M., Wu, M. J., Wang, L. Y., Chow, Y. H., Jiang, S. S., Ch'ang, H. J. & Chang, V. H. S., 四月 1 2017, 於 : PLoS One. 12, 4, e0175586.

研究成果: 雜誌貢獻文章

adenocarcinoma
Transgenic Mice
lung neoplasms
animal models
lungs
5 引文 (Scopus)

KLF10 loss in the pancreas provokes activation of SDF-1 and induces distant metastases of pancreatic ductal adenocarcinoma in the Kras(G12D) p53(flox/flox) model

Weng, C-C., Hawse, J. R., Subramaniam, M., Chang, V. H. S., Yu, W. C. Y., Hung, W-C., Chen, L-T. & Cheng, K-H., 九月 28 2017, 於 : Oncogene. 36, 39, p. 5532-5543 12 p.

研究成果: 雜誌貢獻文章

Pancreas
Adenocarcinoma
Transcription Factors
Neoplasm Metastasis
Neoplasms
3 引文 (Scopus)

Krüpple-like factor 10 regulates radio-sensitivity of pancreatic cancer via UV radiation resistance-associated gene

Chang, V. H. S., Tsai, Y. C., Tsai, Y. L., Peng, S. L., Chen, S. L., Chang, T. M., Yu, W. C. Y. & Ch'ang, H. J., 三月 1 2017, 於 : Radiotherapy and Oncology. 122, 3, p. 476-484

研究成果: 雜誌貢獻文章

Radio
Pancreatic Neoplasms
Radiation
Genes
Autophagy
15 引文 (Scopus)

Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation

Hsieh, M. J., Liu, H. T., Wang, C. N., Huang, H. Y., Lin, Y., Ko, Y. S., Wang, J. S., Chang, V. H. S. & Pang, J. H. S., 三月 1 2017, 於 : Journal of Molecular Medicine. 95, 3, p. 323-333 11 p.

研究成果: 雜誌貢獻文章

Vascular Endothelial Growth Factor Receptor-2
Up-Regulation
Therapeutics
Extremities
Chorioallantoic Membrane
2016
3 引文 (Scopus)
Lactobacillus brevis
Solanum muricatum
Aminobutyrates
Solanum
anti-inflammatory activity
2 引文 (Scopus)
Pneumonia
Genes
Transforming Growth Factors
Molecules
Pulmonary diseases
2015
2 引文 (Scopus)

CDK2 phosphorylation regulates the protein stability of KLF10 by interfering with binding of the E3 ligase SIAH1

Lin, C-H., Lin, S-Y., Chang, H-W., Ko, L-J., Tseng, Y-S., Chang, V. H. S. & Yu, W. C. Y., 五月 1 2015, 於 : Biochimica et Biophysica Acta - Molecular Cell Research. 1853, 5, p. 1174-1181 8 p.

研究成果: 雜誌貢獻文章

Ubiquitin-Protein Ligases
Protein Stability
Phosphorylation
Cell Cycle
Growth
8 引文 (Scopus)

KLF10 affects pancreatic function via the SEI-1/p21Cip1 pathway

Wu, M-J., Wu, W-C., Chang, H-W., Lai, Y-T., Lin, C-H., Yu, W. C. Y. & Chang, V. H. S., 2015, 於 : International Journal of Biochemistry and Cell Biology. 60, p. 53-59 7 p.

研究成果: 雜誌貢獻文章

Genes
Cells
Islets of Langerhans
Pancreas
Transcription Factors
13 引文 (Scopus)
Lovastatin
Cholangiocarcinoma
Heterografts
In Vitro Techniques
gefitinib
6 引文 (Scopus)

Novel use of theta burst cortical electrical stimulation for modulating motor plasticity in rats

Hsieh, T. H., Huang, Y. Z., Chen, J. J. J., Rotenberg, A., Chiang, Y-H., Chien, W. S. C., Chang, H-S., Wang, J-Y. & Peng, C-W., 二月 1 2015, 於 : Journal of Medical and Biological Engineering. 35, 1, p. 62-68 7 p.

研究成果: 雜誌貢獻文章

Motor Evoked Potentials
Electric Stimulation
Plasticity
Rats
Motor Cortex
22 引文 (Scopus)

Underexpression of LKB1 tumor suppressor is associated with enhanced Wnt signaling and malignant characteristics of human intrahepatic cholangiocarcinoma

Wang, J., Zhang, K., Wang, J., Wu, X., Liu, X., Li, B., Zhu, Y., Yu, Y., Cheng, Q., Hu, Z., Guo, C., Hu, S., Mu, B., Tsai, C. H., Li, J., Smith, L., Yang, L., Liu, Q., Chu, P., Chang, V. 及其他4, Zhang, B., Wu, M., Jiang, X. & Yen, Y., 2015, 於 : Oncotarget. 6, 22, p. 18905-18920 16 p.

研究成果: 雜誌貢獻文章

Cholangiocarcinoma
Phosphotransferases
Liver
Catenins
Neoplasms
2014
20 引文 (Scopus)
oxaliplatin
Colorectal Neoplasms
Cell Proliferation
Heterografts
Colonic Neoplasms
2013
12 引文 (Scopus)

Destabilization of KLF10, a tumor suppressor, relies on thr93 phosphorylation and isomerase association

Hwang, Y. C., Yang, C. H., Lin, C. H., Ch'ang, H. J., Chang, V. H. S. & Yu, W. C. Y., 十二月 2013, 於 : Biochimica et Biophysica Acta - Molecular Cell Research. 1833, 12, p. 3035-3045 11 p.

研究成果: 雜誌貢獻文章

Isomerases
Phosphorylation
Neoplasms
Proteins
Peptidylprolyl Isomerase
5 引文 (Scopus)

IbACP, a sixteen-amino-acid peptide isolated from Ipomoea batatas leaves, induces carcinoma cell apoptosis

Chang, V. H. S., Yang, D. H. A., Lin, H. H., Pearce, G., Ryan, C. A. & Chen, Y. C., 2013, 於 : Peptides. 47, p. 148-156 9 p.

研究成果: 雜誌貢獻文章

Ipomoea batatas
Cells
Apoptosis
Carcinoma
Amino Acids
12 引文 (Scopus)
Cyclooxygenase 1
Cell Aggregation
Endothelial cells
Platelets
Platelet Aggregation
2012
18 引文 (Scopus)

Krüppel-like factor 10 expression as a prognostic indicator for pancreatic adenocarcinoma

Chang, V. H. S., Chu, P. Y., Peng, S. L., Mao, T. L., Shan, Y. S., Hsu, C. F., Lin, C. Y., Tsai, K-C., Yu, W. C. Y. & Ch'Ang, H. J., 八月 2012, 於 : American Journal of Pathology. 181, 2, p. 423-430 8 p.

研究成果: 雜誌貢獻文章

Pancreatic Neoplasms
Adenocarcinoma
Transforming Growth Factors
Methylation
Methyltransferases
2011
17 引文 (Scopus)

Klf10 induces cell apoptosis through modulation of BI-1 expression and Ca2+ homeostasis in estrogen-responding adenocarcinoma cells

Hsu, C. F., Sui, C. L., Wu, W. C., Wang, J. J., Yang, D. H. A., Chen, Y. C., Yu, W. C. Y. & Chang, H. S., 四月 2011, 於 : International Journal of Biochemistry and Cell Biology. 43, 4, p. 666-673 8 p.

研究成果: 雜誌貢獻文章

Estrogens
Adenocarcinoma
Homeostasis
Modulation
Apoptosis
2010
10 引文 (Scopus)
Human papillomavirus 16
Oncogene Proteins
Transforming Growth Factor beta
Genes
Apoptosis
2008
17 引文 (Scopus)

DYRK1A stabilizes HPV16E7 oncoprotein through phosphorylation of the threonine 5 and threonine 7 residues

Liang, Y. J., Chang, H. S., Wang, C. Y. & Yu, W. C. Y., 2008, 於 : International Journal of Biochemistry and Cell Biology. 40, 11, p. 2431-2441 11 p.

研究成果: 雜誌貢獻文章

Phosphorylation
Oncogene Proteins
Threonine
Degradation
Half-Life
31 引文 (Scopus)

USP11 stabilizes HPV-16E7 and further modulates the E7 biological activity

Lin, C. H., Chang, H. S. & Yu, W. C. Y., 六月 6 2008, 於 : Journal of Biological Chemistry. 283, 23, p. 15681-15688 8 p.

研究成果: 雜誌貢獻文章

Ubiquitin-Specific Proteases
Human papillomavirus 11
Bioactivity
Ubiquitination
Polyubiquitin
2007
27 引文 (Scopus)

HPV-18 E7 conjugates to c-Myc and mediates its transcriptional activity

Wang, Y. W., Chang, H. S., Lin, C. H. & Yu, W. C. Y., 2007, 於 : International Journal of Biochemistry and Cell Biology. 39, 2, p. 402-412 11 p.

研究成果: 雜誌貢獻文章

Human papillomavirus 18
Transcriptional Activation
Association reactions
Proto-Oncogene Proteins c-myc
Two-Hybrid System Techniques
21 引文 (Scopus)

Increased expression of Dyrk1a in HPV16 immortalized keratinocytes enable evasion of apoptosis

Chang, H. S., Lin, C. H., Yang, C. H., Yen, M. S., Lai, C. R., Chen, Y. R., Liang, Y. J. & Yu, W. C. Y., 六月 1 2007, 於 : International Journal of Cancer. 120, 11, p. 2377-2385 9 p.

研究成果: 雜誌貢獻文章

Keratinocytes
Tyrosine
Phosphotransferases
Apoptosis
Foreskin
2005
13 引文 (Scopus)

Characterization of the wound-inducible protein ipomoelin from sweet potato

Chen, Y. C., Chang, H. S., Lai, H. M. & Jeng, S. T., 二月 2005, 於 : Plant, Cell and Environment. 28, 2, p. 251-259 9 p.

研究成果: 雜誌貢獻文章

Ipomoea batatas
plant damage
sweet potatoes
Wounds and Injuries
Proteins
2004
18 引文 (Scopus)

Cock spermatozoa serve as the gene vector for generation of transgenic chicken (Gallus gallus)

Yang, C. C., Chang, H. S., Lin, C. J., Hsu, C. C., Cheung, J. I., Hwu, L. & Cheng, W. T. K., 七月 2004, 於 : Asian-Australasian Journal of Animal Sciences. 17, 7, p. 885-891 7 p.

研究成果: 雜誌貢獻文章

Gallus gallus
roosters
Liposomes
Spermatozoa
Chickens
50 引文 (Scopus)

Using siRNA technique to generate transgenic animals with spatiotemporal and conditional gene knockdown

Chang, H. S., Lin, C. H., Chen, Y. C. & Yu, W. C. Y., 十一月 2004, 於 : American Journal of Pathology. 165, 5, p. 1535-1541 7 p.

研究成果: 雜誌貢獻文章

Gene Knockdown Techniques
Inborn Genetic Diseases
Genetically Modified Animals
Medical Genetics
Small Interfering RNA
2001
25 引文 (Scopus)

In silico mining of EST databases for novel pre-implantation embryo-specific zinc finger protein genes

Choo, K. B., Chen, H. H., Cheng, W. T. K., Chang, H. S. & Wang, M., 2001, 於 : Molecular Reproduction and Development. 59, 3, p. 249-255 7 p.

研究成果: 雜誌貢獻文章

Expressed Sequence Tags
Zinc Fingers
Computer Simulation
Databases
Genes
2000
23 引文 (Scopus)
Oviducts
Swine
Embryonic Structures
Epithelium
Genes