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研究成果 1988 2019

  • 1073 引文
  • 19 h-指數
  • 89 文章
  • 32 專利
篩選
文章
2019
開啟存取
temozolomide
Glioblastoma
Phenotype
Glioma
Stem Cells
Castration
Autophagy
Prostatic Neoplasms
Cell Death
Osteogenesis
1 引文 (Scopus)

Anti-inflammatory and anti-osteoarthritis effects of Cm-02 and Ck-02

Ho, Y. J., Lu, J. W., Ho, L. J., Lai, J. H., Huang, H. S., Lee, C. C., Lin, T. Y., Lien, S. B., Lin, L. C., Chen, L. W., Gong, Z., Shen, M. C. & Liu, F. C., 九月 10 2019, 於 : Biochemical and Biophysical Research Communications. 517, 1, p. 155-163 9 p.

研究成果: 雜誌貢獻文章

Cartilage
Osteoarthritis
Chondrocytes
Anti-Inflammatory Agents
Chemical activation

Design and Evaluation of PEGylated Liposomal Formulation of a Novel Multikinase Inhibitor for Enhanced Chemosensitivity and Inhibition of Metastatic Pancreatic Ductal Adenocarcinoma

Madamsetty, V. S., Pal, K., Dutta, S. K., Wang, E., Thompson, J. R., Banerjee, R. K., Caulfield, T. R., Mody, K., Yen, Y., Mukhopadhyay, D. & Huang, H-S., 十月 4 2019, 於 : Bioconjugate Chemistry.

研究成果: 雜誌貢獻文章

Epidermal Growth Factor Receptor
gemcitabine
Adenocarcinoma
Chemotherapy
Protein-Tyrosine Kinases
2018

A new niclosamide derivatives-B17 can inhibit urological cancers growth through apoptosis-related pathway

Wu, C-L., Chen, C-L., Huang, H-S. & Yu, D-S., 六月 28 2018, 於 : Cancer Medicine.

研究成果: 雜誌貢獻文章

Niclosamide
Urologic Neoplasms
Apoptosis
Growth
Control Groups
3 引文 (Scopus)

Arthroprotective effects of Cf-02 sharing structural similarity with quercetin

Liu, F. C., Lu, J. W., Chien, C. Y., Huang, H. S., Lee, C. C., Lien, S. B., Lin, L. C., Chen, L. W., Ho, Y. J., Shen, M. C., Ho, L. J. & Lai, J. H., 五月 14 2018, 於 : International Journal of Molecular Sciences. 19, 5, 1453.

研究成果: 雜誌貢獻文章

Quercetin
Nitric oxide
Cartilage
Chondrocytes
arthritis
8 引文 (Scopus)
NF-kappa B
Magnetic resonance
Reporter Genes
Nanoparticles
Lung Neoplasms
2 引文 (Scopus)

Identification and preclinical evaluation of the small molecule, NSC745887, for treating glioblastomas via suppressing DcR3- associated signaling pathways

Fann, L. Y., Chen, Y., Chu, D. C., Weng, S. J., Chu, H. C., Wu, A. T. H., Lee, J. F., Ali, A. A. A., Chen, T. C., Huang, H. S. & Ma, K. H., 一月 1 2018, 於 : Oncotarget. 9, 15, p. 11922-11937 16 p.

研究成果: 雜誌貢獻文章

Glioblastoma
Brain Neoplasms
Caspase 3
Ataxia Telangiectasia Mutated Proteins
Staining and Labeling
4 引文 (Scopus)

Novel technique for repairing posterior medial meniscus root tears using porcine knees and biomechanical study

Wu, J. L., Lee, C. H., Yang, C. T., Chang, C. M., Li, G., Cheng, C. K., Chen, C. H., Huang, H. S. & Lai, Y. S., 二月 1 2018, 於 : PLoS One. 13, 2, e0192027.

研究成果: 雜誌貢獻文章

Tibial Meniscus
knees
Tendons
sutures
Tears
2017
5 引文 (Scopus)

The simultaneous inhibitory effect of niclosamide on RANKL-induced osteoclast formation and osteoblast differentiation

Liu, F. L., Chen, C. L., Lee, C. C., Wu, C. C., Hsu, T. H., Tsai, C. Y., Huang, H. S. & Chang, D. M., 2017, 於 : International Journal of Medical Sciences. 14, 9, p. 840-852 13 p.

研究成果: 雜誌貢獻文章

Niclosamide
Osteoclasts
Osteoblasts
Osteogenesis
Macrophage Colony-Stimulating Factor
2016
4 引文 (Scopus)

A new application of parallel synthesis strategy for discovery of amide-linked small molecules as potent chondroprotective agents in TNF-α-stimulated chondrocytes

Lee, C. C., Lo, Y., Ho, L. J., Lai, J. H., Lien, S. B., Lin, L. C., Chen, C. L., Chen, T. C., Liu, F. C. & Huang, H. S., 三月 1 2016, 於 : PLoS One. 11, 3, e0149317.

研究成果: 雜誌貢獻文章

chondrocytes
Nitric Oxide Synthase Type II
Chondrocytes
amides
Amides
4 引文 (Scopus)

Design, synthesis and biological evaluation of tetracyclic azafluorenone derivatives with topoisomerase I inhibitory properties as potential anticancer agents

Chen, T. C., Yu, D-S., Chen, S-J., Chen, C-L., Lee, C-C., Hsieh, Y-Y., Chang, L-C., Guh, J-H., Lin, J-J. & Huang, H-S., 2016, 於 : Arabian Journal of Chemistry.

研究成果: 雜誌貢獻文章

Type I DNA Topoisomerase
Antineoplastic Agents
Cells
Derivatives
Assays
7 引文 (Scopus)

Design, synthesis and SARs of novel salicylanilides as potent inhibitors of RANKL-induced osteoclastogenesis and bone resorption

Chen, C. L., Lee, C. C., Liu, F. L., Chen, T. C., Ahmed Ali, A. A., Chang, D. M. & Huang, H. S., 七月 19 2016, 於 : European Journal of Medicinal Chemistry. 117, p. 70-84 15 p.

研究成果: 雜誌貢獻文章

Salicylanilides
Osteoclasts
Bone Resorption
Osteogenesis
Bone
2 引文 (Scopus)

Development of 1-Amino-4-(phenylamino)anthraquinone-2-sulfonate Sodium Derivatives as a New Class of Inhibitors of RANKL-Induced Osteoclastogenesis

Lee, C. C., Chen, C. L., Liu, F. L., Chiou, C. Y., Chen, T. C., Wu, C. C., Sun, W. H., Chang, D. M. & Huang, H. S., 五月 1 2016, 於 : Archiv der Pharmazie. 349, 5, p. 342-355 14 p.

研究成果: 雜誌貢獻文章

Osteoclasts
Osteogenesis
Sodium
Bone Resorption
Sodium Compounds
15 引文 (Scopus)

Erlotinib-Conjugated Iron Oxide Nanoparticles as a Smart Cancer-Targeted Theranostic Probe for MRI

Ali, A. A. A., Hsu, F. T., Hsieh, C. L., Shiau, C. Y., Chiang, C. H., Wei, Z. H., Chen, C. Y. & Huang, H. S., 十一月 11 2016, 於 : Scientific Reports. 6, 36650.

研究成果: 雜誌貢獻文章

Nanoparticles
Neoplasms
Transmission Electron Microscopy
Heterografts
Nude Mice

Identification of a new class of WNT1 inhibitor: Cancer cells migration, G-quadruplex stabilization and target validation

Chang, L. C., Chen, T. C., Chen, S. J., Chen, C. L., Lee, C. C., Wu, S. H., Yen, Y., Huang, H. S. & Lin, J. J., 十月 18 2016, 於 : Oncotarget. 7, 42, p. 67986-68001 16 p.

研究成果: 雜誌貢獻文章

G-Quadruplexes
Cell Movement
Neoplasms
Wnt Signaling Pathway
Excipients
9 引文 (Scopus)

Novel anthra[1,2-c][1,2,5]thiadiazole-6,11-diones as promising anticancer lead compounds: Biological evaluation, characterization & molecular targets determination

Ali, A. A. A., Lee, Y. R., Chen, T. C., Chen, C. L., Lee, C. C., Shiau, C. Y., Chiang, C. H. & Huang, H. S., 四月 1 2016, 於 : PLoS One. 11, 4, e0154278.

研究成果: 雜誌貢獻文章

biochemical compounds
Lead compounds
Cells
bioavailability
rifamycins
7 引文 (Scopus)

Selective recognition and stabilization of new ligands targeting the potassium form of the human telomeric G-quadruplex DNA

Lin, Y. H., Chuang, S. M., Wu, P. C., Chen, C. L., Jeyachandran, S., Lo, S. C., Huang, H. S. & Hou, M. H., 八月 11 2016, 於 : Scientific Reports. 6, 31019.

研究成果: 雜誌貢獻文章

Potassium
Stabilization
Ligands
DNA
Anthraquinones
12 引文 (Scopus)

TC-N19, a novel dual inhibitor of EGFR and cMET, efficiently overcomes EGFR-TKI resistance in non-small-cell lung cancer cells

Wu, D. W., Chen, T. C., Huang, H. S. & Lee, H., 六月 30 2016, 於 : Cell death & disease. 7, 6, p. e2290

研究成果: 雜誌貢獻文章

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Paxillin
Heterografts
2015
13 引文 (Scopus)

Discovery of 5-(2′,4′-difluorophenyl)-salicylanilides as new inhibitors of receptor activator of NF-κ°B ligand (RANKL)-induced osteoclastogenesis

Lee, C. C., Liu, F. L., Chen, C. L., Chen, T. C., Chang, D. M. & Huang, H. S., 五月 25 2015, 於 : European Journal of Medicinal Chemistry. 98, p. 115-126 12 p.

研究成果: 雜誌貢獻文章

Salicylanilides
Osteoclasts
Osteogenesis
Ligands
Assays
6 引文 (Scopus)

Novel inhibitors of RANKL-induced osteoclastogenesis: Design, synthesis, and biological evaluation of 6-(2,4-difluorophenyl)-3-phenyl-2H-benzo[e][1,3]oxazine-2,4(3H)-diones

Lee, C. C., Liu, F. L., Chen, C. L., Chen, T. C., Liu, F. C., Ahmed Ali, A. A., Chang, D. M. & Huang, H. S., 七月 23 2015, 於 : Bioorganic and Medicinal Chemistry. 23, 15, p. 4522-4532 11 p.

研究成果: 雜誌貢獻文章

Oxazines
Osteoclasts
Osteogenesis
Assays
Cathepsin K
12 引文 (Scopus)

Ring fusion strategy for synthesis and lead optimization of sulfur-substituted anthra[1,2-c[[1,2,5]thiadiazole-6,11-dione derivatives as promising scaffold of antitumor agents

Lee, Y. R., Chen, T. C., Lee, C. C., Chen, C. L., Ahmed Ali, A. A., Tikhomirov, A., Guh, J. H., Yu, D. S. & Huang, H. S., 九月 18 2015, 於 : European Journal of Medicinal Chemistry. 102, p. 661-676 16 p.

研究成果: 雜誌貢獻文章

Sulfur
Scaffolds
Antineoplastic Agents
Fusion reactions
Apoptosis
15 引文 (Scopus)

Structure-based hybridization, synthesis and biological evaluation of novel tetracyclic heterocyclic azathioxanthone analogues as potential antitumor agents

Chen, T. C., Wu, C. L., Lee, C. C., Chen, C. L., Yu, D. S. & Huang, H. S., 十月 20 2015, 於 : European Journal of Medicinal Chemistry. 103, p. 615-627 13 p.

研究成果: 雜誌貢獻文章

Antineoplastic Agents
Inhibitory Concentration 50
Assays
Cytostatic Agents
Caspase 3

Synthesis and biological evaluation of anthra[1,9-cd]pyrazol-6(2H)-one scaffold derivatives as potential anticancer agents

Chen, T. C., Guh, J. H., Hsu, H. W., Chen, C. L., Lee, C. C., Wu, C. L., Lee, Y. R., Lin, J. J., Yu, D. S. & Huang, H. S., 2015, 於 : Arabian Journal of Chemistry.

研究成果: 雜誌貢獻文章

Scaffolds
Antineoplastic Agents
Cells
Derivatives
losoxantrone
3 引文 (Scopus)

Synthesis and evaluation of new 3-substituted-4-chloro-thioxanthone derivatives as potent anti-breast cancer agents

Chen, C. L., Chen, T. C., Lee, C. C., Shih, L. C., Lin, C. Y., Hsieh, Y. Y., Ali, A. A. A. & Huang, H. S., 2015, 於 : Arabian Journal of Chemistry.

研究成果: 雜誌貢獻文章

Cells
Derivatives
thioxanthone
Screening
Molecules
2014
4 引文 (Scopus)

A novel compound NSC745885 exerts an anti-tumor effect on tongue cancer SAS cells in vitro and in vivo

Chen, Y. W., Huang, H. S., Shieh, Y. S., Ma, K. H., Huang, S. H., Hueng, D. Y., Sytwu, H. K. & Lin, G. J., 八月 15 2014, 於 : PLoS One. 9, 8, e104703.

研究成果: 雜誌貢獻文章

Tongue Neoplasms
tongue
Doxorubicin
Tumors
Anthracyclines
3 引文 (Scopus)

A salicylate-based small molecule HS-Cm exhibits immunomodulatory effects and inhibits dipeptidyl peptidase-IV activity in human T cells

Liou, J. T., Huang, H. S., Chiang, M. L., Lin, C. S., Yang, S. P., Ho, L. J. & Lai, J. H., 三月 5 2014, 於 : European Journal of Pharmacology. 726, 1, p. 124-132 9 p.

研究成果: 雜誌貢獻文章

Dipeptidyl Peptidase 4
Salicylates
Human Activities
T-Lymphocytes
Ionomycin
10 引文 (Scopus)
Sirolimus
Human Activities
Prostatic Neoplasms
Phosphotransferases
Hormones
16 引文 (Scopus)

Modified salicylanilide and 3-phenyl-2 H -benzo[ e ][1,3]oxazine-2,4(3 H)-dione derivatives as novel inhibitors of osteoclast differentiation and bone resorption

Chen, C. L., Liu, F. L., Lee, C. C., Chen, T. C., Ahmed Ali, A. A., Sytwu, H. K., Chang, D. M. & Huang, H. S., 十月 9 2014, 於 : Journal of Medicinal Chemistry. 57, 19, p. 8072-8085 14 p.

研究成果: 雜誌貢獻文章

Salicylanilides
Osteoclasts
Bone Resorption
Osteogenesis
Bone Density Conservation Agents
10 引文 (Scopus)
G-Quadruplexes
Excipients
Lung Neoplasms
Growth
Cyclin B1
11 引文 (Scopus)

Pharmacologic down-regulation of EZH2 suppresses bladder cancer in vitro and in vivo

Tang, S. H., Huang, H. S., Wu, H. U., Tsai, Y. T., Chuang, M. J., Yu, C. P., Huang, S. M., Sun, G. H., Chang, S. Y., Hsiao, P. W., Yu, D. S. & Cha, T. L., 2014, 於 : Oncotarget. 5, 21, p. 10342-10355 14 p.

研究成果: 雜誌貢獻文章

Urinary Bladder Neoplasms
Down-Regulation
Neoplasms
Growth
Emodin
13 引文 (Scopus)

Ring fusion strategy for the synthesis of anthra[2,3-d ]oxazole-2-thione-5,10-dione homologues as DNA topoisomerase inhibitors and as antitumor agents

Chen, C. L., Liu, F. L., Lee, C. C., Chen, T. C., Chang, W. W., Guh, J. H., Ahmed Ali, A. A., Chang, D. M. & Huang, H. S., 十一月 24 2014, 於 : European Journal of Medicinal Chemistry. 87, p. 30-38 9 p.

研究成果: 雜誌貢獻文章

Topoisomerase Inhibitors
Oxazoles
Thiones
Type I DNA Topoisomerase
Antineoplastic Agents
2013
3 引文 (Scopus)

Ascorbigen induces dermal papilla cell proliferation in vitro, but fails to modulate chemotherapy-induced alopecia in vivo

Wang, C. H., Huang, H. S., Dai, N. T., Sheu, M. J. & Chang, D. M., 十二月 2013, 於 : Phytotherapy Research. 27, 12, p. 1863-1867 5 p.

研究成果: 雜誌貢獻文章

Alopecia
Cell Proliferation
Drug Therapy
Skin
Keratinocytes
6 引文 (Scopus)

Brand name or generic? What are the health professionals prescribed for treating diabetes? A longitudinal analysis of the National Health Insurance reimbursement database

Liou, W. S., Hsieh, S. C., Chang, W. Y., Wu, G. H. M., Huang, H. S. & Lee, C., 七月 2013, 於 : Pharmacoepidemiology and Drug Safety. 22, 7, p. 752-759 8 p.

研究成果: 雜誌貢獻文章

Health Insurance Reimbursement
National Health Programs
Names
Databases
Health
13 引文 (Scopus)

Design, synthesis and antiproliferative evaluation of fluorenone analogs with DNA topoisomerase i inhibitory properties

Lee, C. C., Chang, D. M., Huang, K. F., Chen, C. L., Chen, T. C., Lo, Y., Guh, J. H. & Huang, H. S., 十一月 15 2013, 於 : Bioorganic and Medicinal Chemistry. 21, 22, p. 7125-7133 9 p.

研究成果: 雜誌貢獻文章

Type I DNA Topoisomerase
Assays
Screening
DNA
Pharmaceutical Preparations
17 引文 (Scopus)

New Approaches of PARP-1 Inhibitors in Human Lung Cancer Cells and Cancer Stem-Like Cells by Some Selected Anthraquinone-Derived Small Molecules

Lee, Y. R., Yu, D. S., Liang, Y. C., Huang, K. F., Chou, S. J., Chen, T. C., Lee, C. C., Chen, C. L., Chiou, S. H. & Huang, H. S., 二月 25 2013, 於 : PLoS One. 8, 2, e56284.

研究成果: 雜誌貢獻文章

NAD ADP-ribosyltransferase
Anthraquinones
Poly(ADP-ribose) Polymerases
anthraquinones
lung neoplasms
15 引文 (Scopus)

Structure-based design, synthesis and biological evaluation of novel anthra[1,2-d]imidazole-6,11-dione homologues as potential antitumor agents

Chen, T. C., Yu, D. S., Huang, K. F., Fu, Y. C., Lee, C. C., Chen, C. L., Huang, F. C., Hsieh, H. H., Lin, J. J. & Huang, H. S., 2013, 於 : European Journal of Medicinal Chemistry. 69, p. 278-293 16 p.

研究成果: 雜誌貢獻文章

Kidney Neoplasms
Cell proliferation
Cytostatic Agents
Antineoplastic Agents
Assays
25 引文 (Scopus)

Structure-based design, synthesis and evaluation of novel anthra[1,2-d]imidazole-6,11-dione derivatives as telomerase inhibitors and potential for cancer polypharmacology

Chen, C. L., Chang, D. M., Chen, T. C., Lee, C. C., Hsieh, H. H., Huang, F. C., Huang, K. F., Guh, J. H., Lin, J. J. & Huang, H. S., 二月 2013, 於 : European Journal of Medicinal Chemistry. 60, p. 29-41 13 p.

研究成果: 雜誌貢獻文章

Polypharmacology
Telomerase
Cell growth
Derivatives
Neoplasms
2012
13 引文 (Scopus)

A benzamide-linked small molecule NDMC101 inhibits NFATc1 and NF-κB activity: A potential osteoclastogenesis inhibitor for experimental arthritis

Cheng, C. P., Huang, H. S., Hsu, Y. C., Sheu, M. J. & Chang, D. M., 八月 2012, 於 : Journal of Clinical Immunology. 32, 4, p. 762-777 16 p.

研究成果: 雜誌貢獻文章

Experimental Arthritis
Osteogenesis
Osteoclasts
Arthritis
Staining and Labeling
12 引文 (Scopus)

B1, a novel topoisomerase II inhibitor, induces apoptosis and cell cycle G1 arrest in lung adenocarcinoma A549 cells

Cheng, M. H., Yang, Y. C., Wong, Y. H., Chen, T. R., Lee, C. Y., Yang, C. C., Chen, S. H., Yang, I. N., Yang, Y. S., Huang, H. S., Yang, C. Y., Huang, M. S. & Chiu, H. F., 二月 2012, 於 : Anti-Cancer Drugs. 23, 2, p. 191-199 9 p.

研究成果: 雜誌貢獻文章

Topoisomerase II Inhibitors
G1 Phase Cell Cycle Checkpoints
Type II DNA Topoisomerase
Apoptosis
Antineoplastic Agents
15 引文 (Scopus)

Design, synthesis and evaluation of telomerase inhibitory, hTERT repressing, and anti-proliferation activities of symmetrical 1,8-disubstituted amidoanthraquinones

Lee, C. C., Huang, K. F., Chang, D. M., Hsu, J. J., Huang, F. C., Shih, K. N., Chen, C. L., Chen, T. C., Chen, R. H., Lin, J. J. & Huang, H. S., 四月 2012, 於 : European Journal of Medicinal Chemistry. 50, p. 102-112 11 p.

研究成果: 雜誌貢獻文章

Telomerase
Assays
Cytotoxicity
Screening
20 引文 (Scopus)

Synthesis, antiproliferative activities and telomerase inhibition evaluation of novel asymmetrical 1,2-disubstituted amidoanthraquinone derivatives

Lee, C. C., Huang, K. F., Lin, P. Y., Huang, F. C., Chen, C. L., Chen, T. C., Guh, J. H., Lin, J. J. & Huang, H. S., 一月 2012, 於 : European Journal of Medicinal Chemistry. 47, 1, p. 323-336 14 p.

研究成果: 雜誌貢獻文章

Telomerase
Assays
Derivatives
Cell Line
Prostatic Neoplasms
7 引文 (Scopus)

Synthesis, telomerase evaluation and anti-proliferative studies on various series of diaminoanthraquinone-lkinked aminoacyl residue derivatives

Huang, F. C., Huang, K. F., Chen, R. H., Wu, J. E., Chen, T. C., Chen, C. L., Lee, C. C., Chen, J. Y., Lin, J. J. & Huang, H. S., 二月 2012, 於 : Archiv der Pharmazie. 345, 2, p. 101-111 11 p.

研究成果: 雜誌貢獻文章

Telomerase
Anthraquinones
Neoplasms
2011
10 引文 (Scopus)

A benzamide-linked small molecule HS-Cf inhibits TNF-α-induced interferon regulatory factor-1 in porcine chondrocytes: A potential disease-modifying drug for osteoarthritis therapeutics

Liu, F. C., Huang, H. S., Huang, C. Y., Yang, R., Chang, D. M., Lai, J. H. & Ho, L. J., 十二月 2011, 於 : Journal of Clinical Immunology. 31, 6, p. 1131-1142 12 p.

研究成果: 雜誌貢獻文章

Interferon Regulatory Factor-1
Chondrocytes
Interferon-alpha
Osteoarthritis
Swine
21 引文 (Scopus)

Different roles of p53 in the regulation of DNA damage caused by 1,2-heteroannelated anthraquinones and doxorubicin

Chang, Y. L., Lee, H. J., Liu, S. T., Lin, Y. S., Chen, T. C., Hsieh, T. Y., Huang, H. S. & Huang, S. M., 十二月 2011, 於 : International Journal of Biochemistry and Cell Biology. 43, 12, p. 1720-1728 9 p.

研究成果: 雜誌貢獻文章

Anthraquinones
Doxorubicin
DNA Damage
DNA
National Cancer Institute (U.S.)
8 引文 (Scopus)

Investigation of hepatoprotective activity of induced pluripotent stem cells in the mouse model of liver injury

Chiou, S. H., Chiang, C. H., Chang, C. C., Huang, H. C., Chen, Y. J., Tsai, P. H., Jeng, S. Y., Hung, S. I., Hsieh, J. H., Huang, H. S., Lee, F. Y. & Lee, S. D., 2011, 於 : Journal of Biomedicine and Biotechnology. 2011, 219060.

研究成果: 雜誌貢獻文章

Induced Pluripotent Stem Cells
Stem cells
Acute Liver Failure
Liver
Wounds and Injuries
102 引文 (Scopus)

Let-7d functions as novel regulator of epithelial-mesenchymal transition and chemoresistant property in oral cancer

Chang, C. J., Hsu, C. C., Chang, C. H., Tsai, L-L., Chang, Y. C., Lu, S. W., Yu, C. H., Huang, H. S., Wang, J. J., Tsai, C. H., Chou, M. Y., Yu, C. C. & Hu, F. W., 十月 2011, 於 : Oncology Reports. 26, 4, p. 1003-1010 8 p.

研究成果: 雜誌貢獻文章

Epithelial-Mesenchymal Transition
Mouth Neoplasms
Squamous Cell Carcinoma
Aptitude
Snails
28 引文 (Scopus)

The first series of 4,11-bis[(2-aminoethyl)amino]anthra[2,3-b]furan-5,10- diones: Synthesis and anti-proliferative characteristics

Shchekotikhin, A. E., Glazunova, V. A., Dezhenkova, L. G., Shevtsova, E. K., Traven', V. F., Balzarini, J., Huang, H. S., Shtil, A. A. & Preobrazhenskaya, M. N., 一月 2011, 於 : European Journal of Medicinal Chemistry. 46, 1, p. 423-428 6 p.

研究成果: 雜誌貢獻文章

ametantrone
Derivatives
Ethylenediamines
Cells
Anthraquinones
2010
4 引文 (Scopus)

[5,10,15,20-Tetra-(N-methyl-3-pyridyl)porphyrin destabilizes the anti-parallel telomeric quadruplex d(TTAGGG)4].

Dutikova, I. V., Borisova, O. F., Shchelkina, A. K., Lin, J., Huang, S., Shtil', A. A. & Kaliuzhnyǐ, D. N., 九月 2010, 於 : Molekuliarnaia biologiia. 44, 5, p. 929-937 9 p.

研究成果: 雜誌貢獻文章

Porphyrins
G-Quadruplexes
Cultured Tumor Cells
Telomerase
DNA
8 引文 (Scopus)

NSC746364, NSC746365, and NSC746366: The spectra of cytotoxicity and molecular correlates of response to telomerase activity

Huang, H. S., Huang, K. F., Lee, C. C., Chen, C. L., Li, C. L. & Lin, J. J., 二月 2010, 於 : Anti-Cancer Drugs. 21, 2, p. 169-180 12 p.

研究成果: 雜誌貢獻文章

Telomerase
Growth
National Cancer Institute (U.S.)
Telomere
Structure-Activity Relationship