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研究成果 1986 2019

  • 2571 引文
  • 27 h-指數
  • 61 文章
  • 3 章節
  • 1 評論/辯論
篩選
文章
2019
1 引文 (Scopus)

Electrospun polylactic acid (PLLA) microtube array membrane (MTAM)-An advanced substrate for anticancer drug screening

Tseng, C. H., Huang, W. T., Chew, C. H., Lai, J. K., Tu, S. H., Wei, P. L., Lee, K. Y., Lai, G. M. & Chen, C. C., 二月 14 2019, 於 : Materials. 12, 4, 569.

研究成果: 雜誌貢獻文章

開啟存取
Assays
Screening
Membranes
Cells
Acids
2 引文 (Scopus)

Identification of novel anti-liver cancer small molecules with better therapeutic index than sorafenib via zebrafish drug screening platform

Lin, H. S., Huang, Y. L., Wang, Y. R., Hsiao, E., Hsu, T. A., Shiao, H. Y., Jiaang, W. T., Sampurna, B. P., Lin, K. H., Wu, M. S., Lai, G. M. & Yuh, C. H., 六月 1 2019, 於 : Cancers. 11, 6, 739.

研究成果: 雜誌貢獻文章

開啟存取
Preclinical Drug Evaluations
Zebrafish
Liver Neoplasms
Hepatocellular Carcinoma
Inhibitory Concentration 50
1 引文 (Scopus)

Protective effect of Antrodia cinnamomea extract against irradiation-induced acute hepatitis

Kuo, T. H., Kuo, Y. H., Cho, C. Y., Yao, C. J., Lai, G. M. & Chuang, S. E., 二月 2 2019, 於 : International Journal of Molecular Sciences. 20, 4, 846.

研究成果: 雜誌貢獻文章

開啟存取
Antrodia
Bearings (structural)
hepatitis
Radiotherapy
Free radicals
2018
PC12 Cells
Extracellular Signal-Regulated MAP Kinases
Cell Differentiation
Urine
Apoptosis
1 引文 (Scopus)

Opposite regulation of CHOP and GRP78 and synergistic apoptosis induction by selenium yeast and fish oil via AMPK activation in lung adenocarcinoma cells

Kao, R. H., Lai, G. M., Chow, J. M., Liao, C. H., Zheng, Y. M., Tsai, W. L., Hsia, S., Lai, I. C., Lee, H. L., Chuang, S. E., Whang-Peng, J. & Yao, C. J., 十月 8 2018, 於 : Nutrients. 10, 10, 1458.

研究成果: 雜誌貢獻文章

AMP-activated protein kinase
AMP-Activated Protein Kinases
Fish Oils
Selenium
adenocarcinoma
2 引文 (Scopus)
開啟存取
Fear
Fatigue
Survivors
Rehabilitation
Qigong
2017
6 引文 (Scopus)
MAP Kinase Signaling System
Non-Small Cell Lung Carcinoma
Lung Neoplasms
lissamine rhodamine B
Protein-Tyrosine Kinases
11 引文 (Scopus)
Ginsenosides
autophagy
Autophagy
lung neoplasms
Lung Neoplasms
2016
4 引文 (Scopus)
Neoplasms
Apoptosis
Lung Neoplasms
Proteins
Epithelial-Mesenchymal Transition
3 引文 (Scopus)
Radiation Tolerance
Methyltransferases
Down-Regulation
Breast Neoplasms
DNA
16 引文 (Scopus)
Side-Population Cells
Mouth Neoplasms
Heterografts
Neoplastic Stem Cells
Apoptosis
16 引文 (Scopus)

Negative feedback regulation of AXL by miR-34a modulates apoptosis in lung cancer cells

Cho, C. Y., Huang, J. S., Shiah, S. G., Chung, S. Y., Lay, J. D., Yang, Y. Y., Lai, G. M., Cheng, A. L., Chen, L. T. & Chuang, S. E., 二月 1 2016, 於 : RNA. 22, 2, p. 303-315 13 p.

研究成果: 雜誌貢獻文章

MicroRNAs
Lung Neoplasms
Activating Transcription Factors
Apoptosis
MAP Kinase Signaling System
2015
10 引文 (Scopus)

Elimination of cancer stem-like cells and potentiation of temozolomide sensitivity by honokiol in glioblastoma multiforme cells

Lai, I. C., Shih, P. H., Yao, C-J., Yeh, C-T., Wang-Peng, J., Lui, T-N., Chuang, S. E., Hu, T. S., Lai, T-Y. & Lai, G-M., 三月 12 2015, 於 : PLoS One. 10, 3, e0114830.

研究成果: 雜誌貢獻文章

temozolomide
Side-Population Cells
Neoplastic Stem Cells
Glioblastoma
Stem cells
35 引文 (Scopus)

Fucoidan elevates MicroRNA-29b to regulate DNMT3B-MTSS1 axis and inhibit EMT in human hepatocellular carcinoma cells

Yan, M. D., Yao, C. J., Chow, J. M., Chang, C. L., Hwang, P. A., Chuang, S. E., Whang-Peng, J. & Lai, G. M., 十月 1 2015, 於 : Marine Drugs. 13, 10, p. 6099-6116 18 p.

研究成果: 雜誌貢獻文章

MicroRNAs
Hepatocellular Carcinoma
Neoplasm Metastasis
Cadherins
Tumor Suppressor Proteins
32 引文 (Scopus)
Endoplasmic Reticulum Stress
Curcumin
Reactive Oxygen Species
Prostatic Neoplasms
Cell Death
9 引文 (Scopus)

RPS12 increases the invasiveness in cervical cancer activated by c-Myc and inhibited by the dietary flavonoids luteolin and quercetin

Lin, C. W., Lai, G. M., Chen, K. C., Lin, T. H., Fan, J. J., Hsu, R. L., Chou, C. M., Lin, C. M., Kandaswami, C. C., Lee, M. T. & Cheng, C. H., 十二月 1 2015, 於 : Journal of Functional Foods. 19, p. 236-247 12 p.

研究成果: 雜誌貢獻文章

Luteolin
uterine cervical neoplasms
luteolin
Quercetin
Flavonoids
2014
5 引文 (Scopus)

Elimination of cancer stem-like side population in human glioblastoma cells accompanied with stemness gene suppression by Korean herbal recipe MSC500

Yao, C. J., Han, T. Y., Shih, P. H., Yi, T. Y., Lai, I. C., Chang, K. H., Lai, T-I., Chang, C. L. & Lai, G. M., 十一月 19 2014, 於 : Integrative Cancer Therapies. 13, 6, p. 541-554 14 p.

研究成果: 雜誌貢獻文章

Glioblastoma
Side-Population Cells
temozolomide
Neoplastic Stem Cells
Glioma

Erratum: Oxidative stress enhances AXL-mediated cell migration through AKT1/Rac1-dependent mechanism (Free Radical Biology and Medicine (2013) 65 (1246-1256))

Huang, J. S., Cho, C. Y., Hong, C. C., Yan, M. D., Hsieh, M-C., Lay, J. D., Lai, G. M., Ann-Lii, C. & Chuang, S. E., 二月 2014, 於 : Free Radical Biology and Medicine. 67, p. 416 1 p.

研究成果: 雜誌貢獻文章

Oxidative stress
Medicine
Free Radicals
21 引文 (Scopus)

Nobiletin suppresses the proliferation and induces apoptosis involving MAPKs and caspase-8/-9/-3 signals in human acute myeloid leukemia cells

Hsiao, P. C., Lee, W-J., Yang, S. F., Tan, P., Chen, H. Y., Lee, L-M., Chang, J. L., Lai, G-M., Chow, J-M. & Chien, M-H., 十二月 1 2014, 於 : Tumor Biology. 35, 12, p. 11903-11911 9 p.

研究成果: 雜誌貢獻文章

Caspase 9
Caspase 8
Myeloid Cells
Acute Myeloid Leukemia
Apoptosis
2013
10 引文 (Scopus)

Aspirin antagonizes the cytotoxic effect of methotrexate in lung cancer cells

Yan, K. H., Lee, L. M., Hsieh, M-C., Yan, M. D., Yao, C. J., Chang, P. Y., Chen, T. L., Chang, H. Y., Cheng, A. L., Lai, G. M. & Chuang, S. E., 九月 2013, 於 : Oncology Reports. 30, 3, p. 1497-1505 9 p.

研究成果: 雜誌貢獻文章

Methotrexate
Aspirin
Lung Neoplasms
Tetrahydrofolate Dehydrogenase
S Phase
27 引文 (Scopus)
Catenins
Neoplastic Stem Cells
Mouth Neoplasms
Side-Population Cells
Apoptosis
41 引文 (Scopus)

Honokiol-induced apoptosis and autophagy in glioblastoma multiforme cells

Chang, K. H., Yan, M. D., Yao, C. J., Lin, P. C. & Lai, G. M., 十一月 2013, 於 : Oncology Letters. 6, 5, p. 1435-1438 4 p.

研究成果: 雜誌貢獻文章

Autophagy
Glioblastoma
Apoptosis
lissamine rhodamine B
Cell Line
15 引文 (Scopus)

Mefloquine exerts anticancer activity in prostate cancer cells via ROS-mediated modulation of Akt, ERK, JNK and AMPK signaling

Yan, K. H., Yao, C. J., Hsiao, C. H., Lin, K. H., Lin, Y. W., Wen, Y-C., Liu, C. C., Yan, M. D., Chuang, S. E., Lai, G. M. & Lee, L. M., 十月 2013, 於 : Oncology Letters. 5, 5, p. 1541-1545 5 p.

研究成果: 雜誌貢獻文章

Mefloquine
Extracellular Signal-Regulated MAP Kinases
Adenosine Monophosphate
Protein Kinases
Reactive Oxygen Species
11 引文 (Scopus)

Mefloquine induces cell death in prostate cancer cells and provides a potential novel treatment strategy in vivo

Yan, K. H., Lin, Y. W., Hsiao, C. H., Wen, Y-C., Lin, K. H., Liu, C. C., Hsieh, M-C., Yao, C. J., Yan, M. D., Lai, G. M., Chuang, S. E. & Lee, L. M., 十月 2013, 於 : Oncology Letters. 5, 5, p. 1567-1571 5 p.

研究成果: 雜誌貢獻文章

Mefloquine
Prostatic Neoplasms
Cell Death
lissamine rhodamine B
Reactive Oxygen Species
27 引文 (Scopus)

Oxidative stress enhances Axl-mediated cell migration through an Akt1/Rac1-dependent mechanism

Huang, J. S., Cho, C. Y., Hong, C. C., Yan, M. D., Hsieh, M-C., Lay, J. D., Lai, G. M., Cheng, A. L. & Chuang, S. E., 2013, 於 : Free Radical Biology and Medicine. 65, p. 1246-1256 11 p.

研究成果: 雜誌貢獻文章

Oxidative stress
Cell Movement
Reactive Oxygen Species
Oxidative Stress
Phosphatidylinositol 3-Kinases
2012
16 引文 (Scopus)
Side-Population Cells
Hepatocellular Carcinoma
Cell Line
Neoplasms
Neoplastic Stem Cells
64 引文 (Scopus)
Caspases
Cytochromes c
Blood-Brain Barrier
Neuroblastoma
Mitochondria
2011
20 引文 (Scopus)
Catenins
Wnt Signaling Pathway
Colonic Neoplasms
Cell Death
Apoptosis
10 引文 (Scopus)

Targeting PML-RARα and oncogenic signaling pathways by Chinese herbal mixture Tien-Hsien liquid in acute promyelocytic leukemia NB4 cells

Lai, T-I., Yao, C. J., Yang, C. M., Chuang, S. E., Yan, J. L., Liu, C. Y., Chen, S. W., Yan, K. H. & Lai, G. M., 2011, 於 : Evidence-based Complementary and Alternative Medicine. 2011, 984154.

研究成果: 雜誌貢獻文章

Acute Promyelocytic Leukemia
Apoptosis
tien-hsien liquid
Cyclin B1
Cyclin A
2010
31 引文 (Scopus)

The synergistic anticancer effect of troglitazone combined with aspirin causes cell cycle arrest and apoptosis in human lung cancer cells

Yan, K. H., Yao, C. J., Chang, H. Y., Lai, G. M., Cheng, A. L. & Chuang, S. E., 三月 2010, 於 : Molecular Carcinogenesis. 49, 3, p. 235-246 12 p.

研究成果: 雜誌貢獻文章

troglitazone
Cell Cycle Checkpoints
Aspirin
Lung Neoplasms
Apoptosis
2009
88 引文 (Scopus)

Cytotoxic triterpenes from Antrodia camphorata and their mode of action in HT-29 human colon cancer cells

Yeh, C. T., Rao, Y. K., Yao, C. J., Yeh, C. F., Li, C. H., Chuang, S. E., Luong, J. H. T., Lai, G. M. & Tzeng, Y. M., 十一月 18 2009, 於 : Cancer Letters. 285, 1, p. 73-79 7 p.

研究成果: 雜誌貢獻文章

Antrodia
Triterpenes
Colonic Neoplasms
HT29 Cells
Apoptosis
2008
22 引文 (Scopus)

Carbonic anhydrase III promotes transformation and invasion capability in hepatoma cells through FAK signaling pathway

Dai, H. Y., Hong, C. C., Liang, S. C., Yan, M. D., Lai, G. M., Cheng, A. L. & Chuang, S. E., 十二月 2008, 於 : Molecular Carcinogenesis. 47, 12, p. 956-963 8 p.

研究成果: 雜誌貢獻文章

Carbonic Anhydrase III
Focal Adhesion Protein-Tyrosine Kinases
Hepatocellular Carcinoma
Aptitude
Hydro-Lyases
122 引文 (Scopus)

Receptor tyrosine kinase AXL is induced by chemotherapy drugs and overexpression of AXL confers drug resistance in acute myeloid leukemia

Hong, C. C., Lay, J. D., Huang, J. S., Cheng, A. L., Tang, J. L., Lin, M. T., Lai, G. M. & Chuang, S. E., 九月 18 2008, 於 : Cancer Letters. 268, 2, p. 314-324 11 p.

研究成果: 雜誌貢獻文章

U937 Cells
Receptor Protein-Tyrosine Kinases
Drug Resistance
Acute Myeloid Leukemia
Leukemia
2007
50 引文 (Scopus)

Isocostunolide, a sesquiterpene lactone, induces mitochondrial membrane depolarization and caspase-dependent apoptosis in human melanoma cells

Chen, C. N., Huang, H. H., Wu, C. L., Lin, C. P. C., Hsu, J. T. A., Hsieh, H. P., Chuang, S. E. & Lai, G. M., 二月 8 2007, 於 : Cancer Letters. 246, 1-2, p. 237-252 16 p.

研究成果: 雜誌貢獻文章

Sesquiterpenes
Mitochondrial Membranes
Lactones
Caspases
Melanoma
68 引文 (Scopus)

Sulfasalazine suppresses drug resistance and invasiveness of lung adenocarcinoma cells expressing AXL

Lay, J. D., Hong, C. C., Huang, J. S., Yang, Y. Y., Pao, C. Y., Liu, C. H., Lai, Y. P., Lai, G. M., Cheng, A. L., Su, I. J. & Chuang, S. E., 四月 15 2007, 於 : Cancer Research. 67, 8, p. 3878-3887 10 p.

研究成果: 雜誌貢獻文章

Sulfasalazine
Drug Resistance
Non-Small Cell Lung Carcinoma
Receptor Protein-Tyrosine Kinases
Doxorubicin
2006
59 引文 (Scopus)

Dramatic synergistic anticancer effect of clinically achievable doses of lovastatin and troglitazone

Yao, C. J., Lai, G. M., Chan, C. F., Cheng, A. L., Yang, Y. Y. & Chuang, S. E., 三月 1 2006, 於 : International Journal of Cancer. 118, 3, p. 773-779 7 p.

研究成果: 雜誌貢獻文章

troglitazone
Lovastatin
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Cyclin A
Neoplasms
2005
11 引文 (Scopus)
PC12 Cells
Extracellular Signal-Regulated MAP Kinases
Pheochromocytoma
Intermediate Filaments
Urine
71 引文 (Scopus)

Identification and characterization of a novel gene Saf transcribed from the opposite strand of Fas

Yan, M. D., Hong, C. C., Lai, G. M., Cheng, A. L., Lin, Y. W. & Chuang, S. E., 六月 1 2005, 於 : Human Molecular Genetics. 14, 11, p. 1465-1474 10 p.

研究成果: 雜誌貢獻文章

Apoptosis
Genes
Physiological Phenomena
Antisense RNA
Jurkat Cells
2002
137 引文 (Scopus)

Basal levels and patterns of anticancer drug-induced activation of nuclear factor-κB (NF-κB), and its attenuation by tamoxifen, dexamethasone, and curcumin in carcinoma cells

Chuang, S. E., Yeh, P. Y., Lu, Y. S., Lai, G. M., Liao, C. M., Gao, M. & Cheng, A. L., 五月 1 2002, 於 : Biochemical Pharmacology. 63, 9, p. 1709-1716 8 p.

研究成果: 雜誌貢獻文章

Curcumin
Tamoxifen
Dexamethasone
Chemical activation
Cells
61 引文 (Scopus)

Expression of epidermal growth factor receptor in head and neck cancers correlates with clinical progression: A multicentre immunohistochemical study in the Asia-Pacific region

Putti, T. C., To, K. F., Hsu, H. C., Chan, A. T. C., Lai, G. M., Tse, G., Lee, Y. S., Whang-Peng, J., Millward, M., Lin, L., Lin, X. & Lee, C. S., 2002, 於 : Histopathology. 41, 2, p. 144-151 8 p.

研究成果: 雜誌貢獻文章

Head and Neck Neoplasms
Epidermal Growth Factor Receptor
Multicenter Studies
Neoplasms
Hypopharynx
2000
212 引文 (Scopus)

Curcumin-containing diet inhibits diethylnitrosamine-induced murine hepatocarcinogenesis

Chuang, S. E., Kuo, M. L., Hsu, C. H., Chen, C. R., Lin, J. K., Lai, G. M., Hsieh, C. Y. & Cheng, A. L., 2000, 於 : Carcinogenesis. 21, 2, p. 331-335 5 p.

研究成果: 雜誌貢獻文章

Diethylnitrosamine
Curcumin
Diet
Hepatocellular Carcinoma
Mouth Neoplasms
1998
12 引文 (Scopus)

Malignant thyroid teratoma of an adult: A long-term survival after chemotherapy

Chen, J. S., Lai, G. M. & Hsueh, S., 四月 1998, 於 : American Journal of Clinical Oncology: Cancer Clinical Trials. 21, 2, p. 212-214 3 p.

研究成果: 雜誌貢獻文章

Teratoma
Thyroid Gland
Drug Therapy
Survival
Neoplasms
1997
4 引文 (Scopus)

Intensive Chemotherapy plus Recombinant Human Granulocyte Colony Stimulating Factor Support for Distant Metastatic Nasopharyngeal Carcinoma

Wang, C. H., Wang, H. M., Chen, J. S., Chang, W. J. & Lai, G. M., 一月 1997, 於 : Oncology. 54, SUPPL. 1, p. 34-37 4 p.

研究成果: 雜誌貢獻文章

Granulocyte Colony-Stimulating Factor
Drug Therapy
Nasopharyngeal carcinoma
Bone Marrow
Epirubicin
1 引文 (Scopus)

Weekly CAF chemotherapy for advanced breast cancer patients

Hwang, W. S., Hsiung, C. A., Ko, W. S., Wang, C. C., Chang, J. Y., Lai, G. M., Hsieh, R. K., Tsao, C. J., Chen, L. T., Law, C. K., Cheng, A. L., Fan, S. F., Tzeng, C. H., Chiou, T. J. & Whang-Peng, J., 七月 1997, 於 : Oncology. 54, 4, p. 293-297 5 p.

研究成果: 雜誌貢獻文章

Fluorouracil
Doxorubicin
Cyclophosphamide
Breast Neoplasms
Drug Therapy
1996
1 引文 (Scopus)

Clinical trial of low-dose rHuG-CSF in neutropenic cancer patients following anti-cancer chemotherapy

Chang, M. C., Lai, G. M., Tsan, K. W., Wang, R. S. & Wu, J. H., 十一月 1996, 於 : Journal of the Formosan Medical Association = Taiwan yi zhi. 95, 11, p. 845-850 6 p.

研究成果: 雜誌貢獻文章

Clinical Trials
Drug Therapy
Neoplasms
Neutrophils
Myalgia
9 引文 (Scopus)
Mastication
Cisplatin
Lymph Nodes
Neoplasm Metastasis
Drug Therapy
21 引文 (Scopus)

Newly established MST-1 tumour cell line and tumour-infiltrating lymphocyte culture from a patient with soft tissue melanoma (clear cell sarcoma) and their potential applications to patient immunotherapy

Liao, S. K., Perng, Y. P., Lee, L. A., Chang, K. S. S., Lai, G. M., Wong, E. & Ho, Y. S., 二月 1996, 於 : European Journal of Cancer. 32, 2, p. 346-356 11 p.

研究成果: 雜誌貢獻文章

Clear Cell Sarcoma
Tumor-Infiltrating Lymphocytes
Tumor Cell Line
Immunotherapy
Melanoma
46 引文 (Scopus)

Prognostic factors of locoregionally recurrent nasopharyngeal carcinoma - A retrospective review of 182 cases

Yang, T. S., Ng, K. T., Wang, H. M., Wang, C. H., Liaw, C. C. & Lai, G. M., 1996, 於 : American Journal of Clinical Oncology: Cancer Clinical Trials. 19, 4, p. 337-343 7 p.

研究成果: 雜誌貢獻文章

Neoplasm Metastasis
Recurrence
Retreatment
Drug Therapy
Nasopharyngeal carcinoma
1995
17 引文 (Scopus)

Cisplatin and 5-fluorouracil as neoadjuvant chemotherapy: Predicting response in head and neck squamous cell cancer

Wang, H. M., Wang, C. H., Chen, J. S., Chang, H. K., Kiu, M. C., Liaw, C. C., Ng, K. T. & Lai, G. M., 1995, 於 : Journal of the Formosan Medical Association = Taiwan yi zhi. 94, 3, p. 87-94 8 p.

研究成果: 雜誌貢獻文章

Squamous Cell Neoplasms
Head and Neck Neoplasms
Fluorouracil
Cisplatin
Head
13 引文 (Scopus)

Combination chemotherapy with carmustine and cisplatin before, during, and after radiotherapy for adult malignant gliomas

Kiu, M. C., Chang, C. N., Cheng, W. C., Lin, T. K., Wong, C. W., Tang, S. G., Leung, W. M., Chen, L. H., Ho, Y. S., Ng, K. T., Chen, J. S., Yang, T. H. & Lai, G. M., 十月 1995, 於 : Journal of Neuro-Oncology. 25, 3, p. 215-220 6 p.

研究成果: 雜誌貢獻文章

Carmustine
Combination Drug Therapy
Glioma
Cisplatin
Radiotherapy