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研究成果 1986 2019

  • 2615 引文
  • 27 h-指數
  • 61 文章
  • 3 章節
  • 1 評論/辯論
4 引文 (Scopus)
Neoplasms
Apoptosis
Lung Neoplasms
Proteins
Epithelial-Mesenchymal Transition
6 引文 (Scopus)
MAP Kinase Signaling System
Non-Small Cell Lung Carcinoma
Lung Neoplasms
lissamine rhodamine B
Protein-Tyrosine Kinases

Adrenal crisis due to metastatic carcinoma of the adrenal glands.

Wang, J. M. & Lai, G. M., 九月 20 1987, Changgeng yi xue za zhi / Changgeng ji nian yi yuan = Chang Gung medical journal / Chang Gung Memorial Hospital. 3 編輯 卷 10. p. 245-250 6 p.

研究成果: 書貢獻/報告類型章節

Adrenal Gland Neoplasms
Addison Disease
Adrenal Glands
Lung Neoplasms
Adenocarcinoma
21 引文 (Scopus)
Catenins
Wnt Signaling Pathway
Colonic Neoplasms
Cell Death
Apoptosis
11 引文 (Scopus)

Aspirin antagonizes the cytotoxic effect of methotrexate in lung cancer cells

Yan, K. H., Lee, L. M., Hsieh, M-C., Yan, M. D., Yao, C. J., Chang, P. Y., Chen, T. L., Chang, H. Y., Cheng, A. L., Lai, G. M. & Chuang, S. E., 九月 2013, 於 : Oncology Reports. 30, 3, p. 1497-1505 9 p.

研究成果: 雜誌貢獻文章

Methotrexate
Aspirin
Lung Neoplasms
Tetrahydrofolate Dehydrogenase
S Phase
138 引文 (Scopus)

Basal levels and patterns of anticancer drug-induced activation of nuclear factor-κB (NF-κB), and its attenuation by tamoxifen, dexamethasone, and curcumin in carcinoma cells

Chuang, S. E., Yeh, P. Y., Lu, Y. S., Lai, G. M., Liao, C. M., Gao, M. & Cheng, A. L., 五月 1 2002, 於 : Biochemical Pharmacology. 63, 9, p. 1709-1716 8 p.

研究成果: 雜誌貢獻文章

Curcumin
Tamoxifen
Dexamethasone
Chemical activation
Cells
3 引文 (Scopus)

Bone marrow metastases from solid tumors--clinical analysis of 96 cases.

Wang, J. M., Shih, L. Y., Lai, G. M. & Ng, K. T., 十二月 20 1987, Changgeng yi xue za zhi / Changgeng ji nian yi yuan = Chang Gung medical journal / Chang Gung Memorial Hospital. 4 編輯 卷 10. p. 283-293 11 p.

研究成果: 書貢獻/報告類型章節

Bone Marrow Diseases
Nasopharyngeal Neoplasms
Lung Neoplasms
Necrosis
Retrospective Studies
23 引文 (Scopus)

Carbonic anhydrase III promotes transformation and invasion capability in hepatoma cells through FAK signaling pathway

Dai, H. Y., Hong, C. C., Liang, S. C., Yan, M. D., Lai, G. M., Cheng, A. L. & Chuang, S. E., 十二月 2008, 於 : Molecular Carcinogenesis. 47, 12, p. 956-963 8 p.

研究成果: 雜誌貢獻文章

Carbonic Anhydrase III
Focal Adhesion Protein-Tyrosine Kinases
Hepatocellular Carcinoma
Aptitude
Hydro-Lyases
3 引文 (Scopus)
Radiation Tolerance
Methyltransferases
Down-Regulation
Breast Neoplasms
DNA
17 引文 (Scopus)

Cisplatin and 5-fluorouracil as neoadjuvant chemotherapy: Predicting response in head and neck squamous cell cancer

Wang, H. M., Wang, C. H., Chen, J. S., Chang, H. K., Kiu, M. C., Liaw, C. C., Ng, K. T. & Lai, G. M., 1995, 於 : Journal of the Formosan Medical Association = Taiwan yi zhi. 94, 3, p. 87-94 8 p.

研究成果: 雜誌貢獻文章

Squamous Cell Neoplasms
Head and Neck Neoplasms
Fluorouracil
Cisplatin
Head
1 引文 (Scopus)

Clinical trial of low-dose rHuG-CSF in neutropenic cancer patients following anti-cancer chemotherapy

Chang, M. C., Lai, G. M., Tsan, K. W., Wang, R. S. & Wu, J. H., 十一月 1996, 於 : Journal of the Formosan Medical Association = Taiwan yi zhi. 95, 11, p. 845-850 6 p.

研究成果: 雜誌貢獻文章

Clinical Trials
Drug Therapy
Neoplasms
Neutrophils
Myalgia
13 引文 (Scopus)

Combination chemotherapy with carmustine and cisplatin before, during, and after radiotherapy for adult malignant gliomas

Kiu, M. C., Chang, C. N., Cheng, W. C., Lin, T. K., Wong, C. W., Tang, S. G., Leung, W. M., Chen, L. H., Ho, Y. S., Ng, K. T., Chen, J. S., Yang, T. H. & Lai, G. M., 十月 1995, 於 : Journal of Neuro-Oncology. 25, 3, p. 215-220 6 p.

研究成果: 雜誌貢獻文章

Carmustine
Combination Drug Therapy
Glioma
Cisplatin
Radiotherapy
61 引文 (Scopus)

Contribution of glutathione and glutathione‐dependent enzymes in the reversal of adriamycin resistance in colon carcinoma cell lines

Lai, G. M., Moscow, J. A., Alvarez, M. G., Fojo, A. T. & Bates, S. E., 1991, 於 : International Journal of Cancer. 49, 5, p. 688-695 8 p.

研究成果: 雜誌貢獻文章

Buthionine Sulfoximine
Doxorubicin
Glutathione
Colon
Carcinoma
9 引文 (Scopus)
Mastication
Cisplatin
Lymph Nodes
Neoplasm Metastasis
Drug Therapy
Luteolin
uterine cervical neoplasms
luteolin
Quercetin
Flavonoids
213 引文 (Scopus)

Curcumin-containing diet inhibits diethylnitrosamine-induced murine hepatocarcinogenesis

Chuang, S. E., Kuo, M. L., Hsu, C. H., Chen, C. R., Lin, J. K., Lai, G. M., Hsieh, C. Y. & Cheng, A. L., 2000, 於 : Carcinogenesis. 21, 2, p. 331-335 5 p.

研究成果: 雜誌貢獻文章

Diethylnitrosamine
Curcumin
Diet
Hepatocellular Carcinoma
Mouth Neoplasms
89 引文 (Scopus)

Cytotoxic triterpenes from Antrodia camphorata and their mode of action in HT-29 human colon cancer cells

Yeh, C. T., Rao, Y. K., Yao, C. J., Yeh, C. F., Li, C. H., Chuang, S. E., Luong, J. H. T., Lai, G. M. & Tzeng, Y. M., 十一月 18 2009, 於 : Cancer Letters. 285, 1, p. 73-79 7 p.

研究成果: 雜誌貢獻文章

Antrodia
Triterpenes
Colonic Neoplasms
HT29 Cells
Apoptosis
11 引文 (Scopus)
PC12 Cells
Extracellular Signal-Regulated MAP Kinases
Pheochromocytoma
Intermediate Filaments
Urine
59 引文 (Scopus)

Dramatic synergistic anticancer effect of clinically achievable doses of lovastatin and troglitazone

Yao, C. J., Lai, G. M., Chan, C. F., Cheng, A. L., Yang, Y. Y. & Chuang, S. E., 三月 1 2006, 於 : International Journal of Cancer. 118, 3, p. 773-779 7 p.

研究成果: 雜誌貢獻文章

troglitazone
Lovastatin
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Cyclin A
Neoplasms
154 引文 (Scopus)

Effect of glutathione on DNA repair in cisplatin-resistant human ovarian cancer cell lines

Lai, G. M., Ozols, R. F., Young, R. C. & Hamilton, T. C., 四月 5 1989, 於 : Journal of the National Cancer Institute. 81, 7, p. 535-539 5 p.

研究成果: 雜誌貢獻文章

Cisplatin
Ovarian Cancer
Glutathione
DNA Repair
Ovarian Neoplasms
1 引文 (Scopus)

Electrospun polylactic acid (PLLA) microtube array membrane (MTAM)-An advanced substrate for anticancer drug screening

Tseng, C. H., Huang, W. T., Chew, C. H., Lai, J. K., Tu, S. H., Wei, P. L., Lee, K. Y., Lai, G. M. & Chen, C. C., 二月 14 2019, 於 : Materials. 12, 4, 569.

研究成果: 雜誌貢獻文章

開啟存取
Assays
Screening
Membranes
Cells
Acids
11 引文 (Scopus)

Elimination of cancer stem-like cells and potentiation of temozolomide sensitivity by honokiol in glioblastoma multiforme cells

Lai, I. C., Shih, P. H., Yao, C-J., Yeh, C-T., Wang-Peng, J., Lui, T-N., Chuang, S. E., Hu, T. S., Lai, T-Y. & Lai, G-M., 三月 12 2015, 於 : PLoS One. 10, 3, e0114830.

研究成果: 雜誌貢獻文章

temozolomide
Side-Population Cells
Neoplastic Stem Cells
Glioblastoma
Stem cells
16 引文 (Scopus)
Side-Population Cells
Hepatocellular Carcinoma
Cell Line
Neoplasms
Neoplastic Stem Cells
5 引文 (Scopus)

Elimination of cancer stem-like side population in human glioblastoma cells accompanied with stemness gene suppression by Korean herbal recipe MSC500

Yao, C. J., Han, T. Y., Shih, P. H., Yi, T. Y., Lai, I. C., Chang, K. H., Lai, T-I., Chang, C. L. & Lai, G. M., 十一月 19 2014, 於 : Integrative Cancer Therapies. 13, 6, p. 541-554 14 p.

研究成果: 雜誌貢獻文章

Glioblastoma
Side-Population Cells
temozolomide
Neoplastic Stem Cells
Glioma
149 引文 (Scopus)

Enhanced DNA repair and resistance to cisplatin in human ovarian cancer

Lai, G. M., Ozols, R. F., Smyth, J. F., Young, R. C. & Hamilton, T. C., 十二月 15 1988, 於 : Biochemical Pharmacology. 37, 24, p. 4597-4600 4 p.

研究成果: 雜誌貢獻文章

Aphidicolin
Diterpenes
Cisplatin
Repair
DNA
95 引文 (Scopus)

Epidemiological characteristics and multiple risk factors of stomach cancer in Taiwan

Lee, H. H., Wu, H. Y., Chuang, Y. C., Chang, A. S., Chao, H. H., Chen, K. Y., Chen, H. K., Lai, G. M., Huang, H. H. & Chen, C. J., 1990, 於 : Anticancer Research. 10, 4, p. 875-882 8 p.

研究成果: 雜誌貢獻文章

Taiwan
Stomach Neoplasms
Meat
Stomach Diseases
Food
75 引文 (Scopus)

Epidemiologic characteristics and multiple risk factors of lung cancer in Taiwan

Chen, C. J., Wu, H. Y., Chuang, Y. C., Chang, A. S., Luh, K. T., Chao, H. H., Chen, K. Y., Chen, S. G., Lai, G. M., Huang, H. H. & Lee, H. H., 1990, 於 : Anticancer Research. 10, 4, p. 971-976 6 p.

研究成果: 雜誌貢獻文章

Taiwan
Lung Neoplasms
Mortality
Smoking
Indoor Air Pollution

Erratum: Oxidative stress enhances AXL-mediated cell migration through AKT1/Rac1-dependent mechanism (Free Radical Biology and Medicine (2013) 65 (1246-1256))

Huang, J. S., Cho, C. Y., Hong, C. C., Yan, M. D., Hsieh, M-C., Lay, J. D., Lai, G. M., Ann-Lii, C. & Chuang, S. E., 二月 2014, 於 : Free Radical Biology and Medicine. 67, p. 416 1 p.

研究成果: 雜誌貢獻文章

Oxidative stress
Medicine
Free Radicals
61 引文 (Scopus)

Expression of epidermal growth factor receptor in head and neck cancers correlates with clinical progression: A multicentre immunohistochemical study in the Asia-Pacific region

Putti, T. C., To, K. F., Hsu, H. C., Chan, A. T. C., Lai, G. M., Tse, G., Lee, Y. S., Whang-Peng, J., Millward, M., Lin, L., Lin, X. & Lee, C. S., 2002, 於 : Histopathology. 41, 2, p. 144-151 8 p.

研究成果: 雜誌貢獻文章

Head and Neck Neoplasms
Epidermal Growth Factor Receptor
Multicenter Studies
Neoplasms
Hypopharynx
41 引文 (Scopus)

Fucoidan elevates MicroRNA-29b to regulate DNMT3B-MTSS1 axis and inhibit EMT in human hepatocellular carcinoma cells

Yan, M. D., Yao, C. J., Chow, J. M., Chang, C. L., Hwang, P. A., Chuang, S. E., Whang-Peng, J. & Lai, G. M., 十月 1 2015, 於 : Marine Drugs. 13, 10, p. 6099-6116 18 p.

研究成果: 雜誌貢獻文章

MicroRNAs
Hepatocellular Carcinoma
Neoplasm Metastasis
Cadherins
Tumor Suppressor Proteins
29 引文 (Scopus)
Catenins
Neoplastic Stem Cells
Mouth Neoplasms
Side-Population Cells
Apoptosis
43 引文 (Scopus)

Honokiol-induced apoptosis and autophagy in glioblastoma multiforme cells

Chang, K. H., Yan, M. D., Yao, C. J., Lin, P. C. & Lai, G. M., 十一月 2013, 於 : Oncology Letters. 6, 5, p. 1435-1438 4 p.

研究成果: 雜誌貢獻文章

Autophagy
Glioblastoma
Apoptosis
lissamine rhodamine B
Cell Line
18 引文 (Scopus)
Side-Population Cells
Mouth Neoplasms
Heterografts
Neoplastic Stem Cells
Apoptosis
68 引文 (Scopus)
Caspases
Cytochromes c
Blood-Brain Barrier
Neuroblastoma
Mitochondria
PC12 Cells
Extracellular Signal-Regulated MAP Kinases
Cell Differentiation
Urine
Apoptosis
72 引文 (Scopus)

Identification and characterization of a novel gene Saf transcribed from the opposite strand of Fas

Yan, M. D., Hong, C. C., Lai, G. M., Cheng, A. L., Lin, Y. W. & Chuang, S. E., 六月 1 2005, 於 : Human Molecular Genetics. 14, 11, p. 1465-1474 10 p.

研究成果: 雜誌貢獻文章

Apoptosis
Genes
Physiological Phenomena
Antisense RNA
Jurkat Cells
5 引文 (Scopus)

Identification of novel anti-liver cancer small molecules with better therapeutic index than sorafenib via zebrafish drug screening platform

Lin, H. S., Huang, Y. L., Wang, Y. R., Hsiao, E., Hsu, T. A., Shiao, H. Y., Jiaang, W. T., Sampurna, B. P., Lin, K. H., Wu, M. S., Lai, G. M. & Yuh, C. H., 六月 1 2019, 於 : Cancers. 11, 6, 739.

研究成果: 雜誌貢獻文章

開啟存取
Preclinical Drug Evaluations
Zebrafish
Liver Neoplasms
Hepatocellular Carcinoma
Inhibitory Concentration 50
295 引文 (Scopus)

Increased DNA repair as a mechanism of acquired resistance to cis-diamminedichloroplatinum(II) in human ovarian cancer cell lines

Masuda, H., Ozols, R. F., Lai, G. M., Fojo, A., Rothenberg, M. & Hamilton, T. C., 1988, 於 : Cancer Research. 48, 20, p. 5713-5716 4 p.

研究成果: 雜誌貢獻文章

DNA Repair
Ovarian Neoplasms
Cisplatin
Cell Line
DNA
13 引文 (Scopus)
Ginsenosides
autophagy
Autophagy
lung neoplasms
Lung Neoplasms
4 引文 (Scopus)

Intensive Chemotherapy plus Recombinant Human Granulocyte Colony Stimulating Factor Support for Distant Metastatic Nasopharyngeal Carcinoma

Wang, C. H., Wang, H. M., Chen, J. S., Chang, W. J. & Lai, G. M., 一月 1997, 於 : Oncology. 54, SUPPL. 1, p. 34-37 4 p.

研究成果: 雜誌貢獻文章

Granulocyte Colony-Stimulating Factor
Drug Therapy
Nasopharyngeal carcinoma
Bone Marrow
Epirubicin
52 引文 (Scopus)

Isocostunolide, a sesquiterpene lactone, induces mitochondrial membrane depolarization and caspase-dependent apoptosis in human melanoma cells

Chen, C. N., Huang, H. H., Wu, C. L., Lin, C. P. C., Hsu, J. T. A., Hsieh, H. P., Chuang, S. E. & Lai, G. M., 二月 8 2007, 於 : Cancer Letters. 246, 1-2, p. 237-252 16 p.

研究成果: 雜誌貢獻文章

Sesquiterpenes
Mitochondrial Membranes
Lactones
Caspases
Melanoma

Malignant germ cell tumors in adults and adolescents--analysis of 36 cases including testis, mediastinum and retroperitoneum origins

Liaw, C. C., Ng, K. T., Lai, G. M., Chen, M. H., Lin, F. J. & Huang, M. H., 九月 20 1986, Changgeng yi xue za zhi / Changgeng ji nian yi yuan = Chang Gung medical journal / Chang Gung Memorial Hospital. 3 編輯 卷 9. p. 194-203 10 p.

研究成果: 書貢獻/報告類型章節

Mesonephroma
Retroperitoneal Neoplasms
Mediastinal Neoplasms
Dysgerminoma
Germ Cell and Embryonal Neoplasms
12 引文 (Scopus)

Malignant thyroid teratoma of an adult: A long-term survival after chemotherapy

Chen, J. S., Lai, G. M. & Hsueh, S., 四月 1998, 於 : American Journal of Clinical Oncology: Cancer Clinical Trials. 21, 2, p. 212-214 3 p.

研究成果: 雜誌貢獻文章

Teratoma
Thyroid Gland
Drug Therapy
Survival
Neoplasms
58 引文 (Scopus)

Mechanisms of resistance to cisplatin and alkylating agents.

Hamilton, T. C., Lai, G. M., Rothenberg, M. L., Fojo, A. T., Young, R. C. & Ozols, R. F., 1989, 於 : Cancer Treatment and Research. 48, p. 151-169 19 p.

研究成果: 雜誌貢獻文章

Alkylating Agents
Drug Resistance
Ovarian Neoplasms
Cisplatin
15 引文 (Scopus)

Mefloquine exerts anticancer activity in prostate cancer cells via ROS-mediated modulation of Akt, ERK, JNK and AMPK signaling

Yan, K. H., Yao, C. J., Hsiao, C. H., Lin, K. H., Lin, Y. W., Wen, Y-C., Liu, C. C., Yan, M. D., Chuang, S. E., Lai, G. M. & Lee, L. M., 十月 2013, 於 : Oncology Letters. 5, 5, p. 1541-1545 5 p.

研究成果: 雜誌貢獻文章

Mefloquine
Extracellular Signal-Regulated MAP Kinases
Adenosine Monophosphate
Protein Kinases
Reactive Oxygen Species
13 引文 (Scopus)

Mefloquine induces cell death in prostate cancer cells and provides a potential novel treatment strategy in vivo

Yan, K. H., Lin, Y. W., Hsiao, C. H., Wen, Y-C., Lin, K. H., Liu, C. C., Hsieh, M-C., Yao, C. J., Yan, M. D., Lai, G. M., Chuang, S. E. & Lee, L. M., 十月 2013, 於 : Oncology Letters. 5, 5, p. 1567-1571 5 p.

研究成果: 雜誌貢獻文章

Mefloquine
Prostatic Neoplasms
Cell Death
lissamine rhodamine B
Reactive Oxygen Species
34 引文 (Scopus)

Meningeal carcinomatosis from solid tumors: clinical analysis of 42 cases.

Liaw, C. C., Ng, K. T., Huang, J. S., Wang, C. H., Kiu, M. C. & Lai, G. M., 三月 1992, 於 : Journal of the Formosan Medical Association = Taiwan yi zhi. 91, 3, p. 299-303 5 p.

研究成果: 雜誌貢獻文章

Meningeal Carcinomatosis
Radiotherapy
Methotrexate
Breast Neoplasms
Neoplasms
18 引文 (Scopus)

Negative feedback regulation of AXL by miR-34a modulates apoptosis in lung cancer cells

Cho, C. Y., Huang, J. S., Shiah, S. G., Chung, S. Y., Lay, J. D., Yang, Y. Y., Lai, G. M., Cheng, A. L., Chen, L. T. & Chuang, S. E., 二月 1 2016, 於 : RNA. 22, 2, p. 303-315 13 p.

研究成果: 雜誌貢獻文章

MicroRNAs
Lung Neoplasms
Activating Transcription Factors
Apoptosis
MAP Kinase Signaling System
21 引文 (Scopus)

Newly established MST-1 tumour cell line and tumour-infiltrating lymphocyte culture from a patient with soft tissue melanoma (clear cell sarcoma) and their potential applications to patient immunotherapy

Liao, S. K., Perng, Y. P., Lee, L. A., Chang, K. S. S., Lai, G. M., Wong, E. & Ho, Y. S., 二月 1996, 於 : European Journal of Cancer. 32, 2, p. 346-356 11 p.

研究成果: 雜誌貢獻文章

Clear Cell Sarcoma
Tumor-Infiltrating Lymphocytes
Tumor Cell Line
Immunotherapy
Melanoma
22 引文 (Scopus)

Nobiletin suppresses the proliferation and induces apoptosis involving MAPKs and caspase-8/-9/-3 signals in human acute myeloid leukemia cells

Hsiao, P. C., Lee, W-J., Yang, S. F., Tan, P., Chen, H. Y., Lee, L-M., Chang, J. L., Lai, G-M., Chow, J-M. & Chien, M-H., 十二月 1 2014, 於 : Tumor Biology. 35, 12, p. 11903-11911 9 p.

研究成果: 雜誌貢獻文章

Caspase 9
Caspase 8
Myeloid Cells
Acute Myeloid Leukemia
Apoptosis