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研究成果 2012 2019

  • 762 引文
  • 12 h-指數
  • 34 文章
  • 1 回顧型文獻
2019

Immune effector monocyte–neutrophil cooperation induced by the primary tumor prevents metastatic progression of breast cancer

Hagerling, C., Gonzalez, H., Salari, K., Wang, C. Y., Lin, C., Robles, I., van Gogh, M., Dejmek, A., Jirström, K. & Werb, Z., 十月 22 2019, 於 : Proceedings of the National Academy of Sciences of the United States of America. 116, 43, p. 21704-21714 11 p.

研究成果: 雜誌貢獻文章

開啟存取
Monocytes
Neutrophils
Breast Neoplasms
Neoplasms
Lung
1 引文 (Scopus)

RasGRP1 is a potential biomarker for stratifying anti-EGFR therapy response in colorectal cancer

Gbenedio, O. M., Bonnans, C., Grun, D., Wang, C. Y., Hatch, A. J., Mahoney, M. R., Barras, D., Matli, M., Miao, Y., Christopher Garcia, K., Tejpar, S., Delorenzi, M., Venook, A. P., Nixon, A. B., Warren, R. S., Roose, J. P. & Depeille, P., 八月 8 2019, 於 : JCI insight. 4, 15, e127552.

研究成果: 雜誌貢獻文章

開啟存取
Colorectal Neoplasms
Biomarkers
Therapeutics
Organoids
Drug Therapy
2018
11 引文 (Scopus)

Distinct expression of CDCA3, CDCA5, and CDCA8 leads to shorter relapse free survival in breast cancer patient

Phan, N. N., Wang, C. Y., Li, K. L., Chen, C. F., Chiao, C. C., Yu, H. G., Huang, P. L. & Lin, Y. C., 一月 1 2018, 於 : Oncotarget. 9, 6, p. 6977-6992 16 p.

研究成果: 雜誌貢獻文章

開啟存取
Breast Neoplasms
Recurrence
Survival
cdc Genes
Genes
5 引文 (Scopus)

Endovascular Biopsy: In Vivo Cerebral Aneurysm Endothelial Cell Sampling and Gene Expression Analysis

Cooke, D. L., McCoy, D. B., Halbach, V. V., Hetts, S. W., Amans, M. R., Dowd, C. F., Higashida, R. T., Lawson, D., Nelson, J., Wang, C. Y., Kim, H., Werb, Z., McCulloch, C., Hashimoto, T., Su, H. & Sun, Z., 二月 1 2018, 於 : Translational Stroke Research. 9, 1, p. 20-33 14 p.

研究成果: 雜誌貢獻文章

Intracranial Aneurysm
Endothelial Cells
Biopsy
Gene Expression
Aneurysm
2 引文 (Scopus)

Homoharringtonine induced immune alteration for an Efficient Anti-tumor Response in Mouse Models of Non-small Cell Lung Adenocarcinoma Expressing Kras Mutation

Weng, T. Y., Wu, H. F., Li, C. Y., Hung, Y. H., Chang, Y. W., Chen, Y. L., Hsu, H. P., Chen, Y. H., Wang, C. Y., Chang, J. Y. & Lai, M. D., 十二月 1 2018, 於 : Scientific Reports. 8, 1, 8216.

研究成果: 雜誌貢獻文章

開啟存取
Mutation
Neoplasms
B-Lymphocytes
Lung
Cytokines
6 引文 (Scopus)

Single-cell RNA sequencing reveals gene expression signatures of breast cancer-associated endothelial cells

Sun, Z., Wang, C. Y., Lawson, D. A., Kwek, S., Velozo, H. G., Owyong, M., Lai, M. D., Fong, L., Wilson, M., Su, H., Werb, Z. & Cooke, D. L., 一月 1 2018, 於 : Oncotarget. 9, 13, p. 10945-10961 17 p.

研究成果: 雜誌貢獻文章

開啟存取
RNA Sequence Analysis
Transcriptome
Endothelial Cells
Breast Neoplasms
Genes
2017
7 引文 (Scopus)

Argininosuccinate lyase interacts with cyclin A2 in cytoplasm and modulates growth of liver tumor cells

Hung, Y. H., Huang, H. L., Chen, W. C., Yen, M. C., Cho, C. Y., Weng, T. Y., Wang, C. Y., Chen, Y. L., Chen, L. T. & Lai, M. D., 二月 1 2017, 於 : Oncology Reports. 37, 2, p. 969-978 10 p.

研究成果: 雜誌貢獻文章

開啟存取
Cyclin A2
Argininosuccinate Lyase
Cytoplasm
Liver
Growth
15 引文 (Scopus)

Cyclin D1 overexpression correlates with poor tumor differentiation and prognosis in gastric cancer

Shan, Y. S., Hsu, H. P., Lai, M. D., Hung, Y. H., Wang, C. Y., Yen, M. C. & Chen, Y. L., 一月 1 2017, 於 : Oncology Letters. 14, 4, p. 4517-4526 10 p.

研究成果: 雜誌貢獻文章

開啟存取
Cyclin D1
Stomach Neoplasms
Cyclin D2
Stomach
Cyclin D
13 引文 (Scopus)

GATA3 targets semaphorin 3B in mammary epithelial cells to suppress breast cancer progression and metastasis

Shahi, P., Wang, C. Y., Chou, J., Hagerling, C., Gonzalez Velozo, H., Ruderisch, A., Yu, Y., Lai, M. D. & Werb, Z., 十月 5 2017, 於 : Oncogene. 36, 40, p. 5567-5575 9 p.

研究成果: 雜誌貢獻文章

Semaphorins
Breast
Epithelial Cells
Breast Neoplasms
Neoplasm Metastasis
1 引文 (Scopus)

Novel therapeutic effects of sesamin on diabetes-induced cardiac dysfunction

Thuy, T. D., Phan, N. N., Wang, C. Y., Yu, H. G., Wang, S. Y., Huang, P. L., Do, Y. Y. & Lin, Y. C., 一月 1 2017, 於 : Molecular Medicine Reports. 15, 5, p. 2949-2956 8 p.

研究成果: 雜誌貢獻文章

開啟存取
Therapeutic Uses
Medical problems
Experimental Diabetes Mellitus
Cardiomegaly
Bioinformatics
4 引文 (Scopus)

PSMB5 plays a dual role in cancer development and immunosuppression

Wang, C. Y., Li, C. Y., Hsu, H. P., Cho, C. Y., Yen, M. C., Weng, T. Y., Chen, W. C., Hung, Y. H., Lee, K. T., Hung, J. H., Chen, Y. L. & Lai, M. D., 一月 1 2017, 於 : American Journal of Cancer Research. 7, 11, p. 2103-2120 18 p.

研究成果: 雜誌貢獻文章

Immunosuppression
Neoplasms
Proteasome Endopeptidase Complex
Computational Biology
Macrophages
7 引文 (Scopus)

Silencing of argininosuccinate lyase inhibits colorectal cancer formation

Huang, H. L., Chen, W. C., Hsu, H. P., Cho, C. Y., Hung, Y. H., Wang, C. Y. & Lai, M. D., 一月 1 2017, 於 : Oncology Reports. 37, 1, p. 163-170 8 p.

研究成果: 雜誌貢獻文章

開啟存取
Argininosuccinate Lyase
Colorectal Neoplasms
Colonic Neoplasms
Nitric Oxide
Small Interfering RNA

Systematic analysis of the achaete-scute complex-like gene signature in clinical cancer patients

Wang, C-Y., Shahi, P., Huang, J. T. W., Phan, N. N., Sun, Z., Lin, Y-C., Lai, M-D. & Werb, Z., 一月 2017, 於 : Molecular and Clinical Oncology. 6, 1, p. 7-18 12 p.

研究成果: 雜誌貢獻文章

Achaete-Scute Complex Genome Region
Neoplasms
Colonic Neoplasms
Breast Neoplasms
Brain Neoplasms
22 引文 (Scopus)

Voltage-gated calcium channels: Novel targets for cancer therapy

Phan, N. N., Wang, C. Y., Chen, C. F., Sun, Z., Lai, M. D. & Lin, Y. C., 一月 1 2017, 於 : Oncology Letters. 14, 2, p. 2059-2074 16 p.

研究成果: 雜誌貢獻文章

開啟存取
Calcium Channels
Genes
Neoplasms
Brain Neoplasms
Kidney Neoplasms
6 引文 (Scopus)

ZNF503/Zpo2 drives aggressive breast cancer progression by down-regulation of GATA3 expression

Shahi, P., Wang, C. Y., Lawson, D. A., Slorach, E. M., Lu, A., Yu, Y., Lai, M. D., Velozo, H. G. & Werb, Z., 三月 21 2017, 於 : Proceedings of the National Academy of Sciences of the United States of America. 114, 12, p. 3169-3174 6 p.

研究成果: 雜誌貢獻文章

開啟存取
Down-Regulation
Breast Neoplasms
GATA3 Transcription Factor
Breast
Epithelial Cells
2016
10 引文 (Scopus)

Cancer stem cell marker CD90 inhibits ovarian cancer formation via β3 integrin

Chen, W. C., Hsu, H. P., Li, C. Y., Yang, Y. J., Hung, Y. H., Cho, C. Y., Wang, C. Y., Weng, T. Y. & Lai, M. D., 十一月 1 2016, 於 : International Journal of Oncology. 49, 5, p. 1881-1889 9 p.

研究成果: 雜誌貢獻文章

開啟存取
Neoplastic Stem Cells
Integrins
Ovarian Neoplasms
Growth
Anoikis
17 引文 (Scopus)

Differential expression pattern of THBS1 and THBS2 in lung cancer: Clinical outcome and a systematic-analysis of microarray databases

Weng, T. Y., Wang, C. Y., Hung, Y. H., Chen, W. C., Chen, Y. L. & Lai, M. D., 八月 1 2016, 於 : PLoS ONE. 11, 8, e0161007.

研究成果: 雜誌貢獻文章

開啟存取
Thrombospondin 1
lung neoplasms
Microarray Analysis
Microarrays
adenocarcinoma
10 引文 (Scopus)

MST3 promotes proliferation and tumorigenicity through the VAV2/Rac1 signal axis in breast cancer

Cho, C. Y., Lee, K. T., Chen, W. C., Wang, C. Y., Chang, Y. S., Huang, H. L., Hsu, H. P., Yen, M. C., Lai, M. Z. & Lai, M. D., 三月 22 2016, 於 : Oncotarget. 7, 12, p. 14586-14604 19 p.

研究成果: 雜誌貢獻文章

Phosphotransferases
Breast Neoplasms
Proline
Growth
Down-Regulation
3 引文 (Scopus)

Novel regulations of MEF2-A, MEF2-D, and CACNA1S in the functional incompetence of adipose-derived mesenchymal stem cells by induced indoxyl sulfate in chronic kidney disease

Thi Do, D., Phan, N. N., Wang, C. Y., Sun, Z. & Lin, Y. C., 十二月 1 2016, 於 : Cytotechnology. 68, 6, p. 2589-2604 16 p.

研究成果: 雜誌貢獻文章

Indican
Stem cells
Mesenchymal Stromal Cells
Chronic Renal Insufficiency
Regeneration
26 引文 (Scopus)

Systematic analysis of gene expression alterations and clinical outcomes for long-chain acyl-coenzyme A synthetase family in cancer

Chen, W. C., Wang, C. Y., Hung, Y. H., Weng, T. Y., Yen, M. C. & Lai, M. D., 五月 1 2016, 於 : PLoS ONE. 11, 5, e0155660.

研究成果: 雜誌貢獻文章

開啟存取
Coenzyme A Ligases
acyl coenzyme A
ligases
Gene expression
prognosis
2015
10 引文 (Scopus)

Argininosuccinate lyase is a potential therapeutic target in breast cancer

Huang, H. L., Chen, W. C., Hsu, H. P., Cho, C. Y., Hung, Y. H., Wang, C. Y. & Lai, M. D., 十二月 1 2015, 於 : Oncology Reports. 34, 6, p. 3131-3139 9 p.

研究成果: 雜誌貢獻文章

開啟存取
Argininosuccinate Lyase
Breast Neoplasms
Cyclin A2
Small Interfering RNA
Autophagy
4 引文 (Scopus)

Endovascular biopsy: Strategy for analyzing gene expression profiles of individual endothelial cells obtained from human vessels

Sun, Z., Lawson, D. A., Sinclair, E., Wang, C. Y., Lai, M. D., Hetts, S. W., Higashida, R. T., Dowd, C. F., Halbach, V. V., Werb, Z., Su, H. & Cooke, D. L., 九月 1 2015, 於 : Biotechnology Reports. 7, p. 157-165 9 p., 106.

研究成果: 雜誌貢獻文章

開啟存取
Transcriptome
Endothelial Cells
Biopsy
Flow Cytometry
Leukocytes
103 引文 (Scopus)

Matrix metalloproteinases in stem cell regulation and cancer

Kessenbrock, K., Wang, C. Y. & Werb, Z., 五月 1 2015, 於 : Matrix Biology. 44-46, p. 184-190 7 p.

研究成果: 雜誌貢獻回顧型文獻

開啟存取
Neoplastic Stem Cells
Matrix Metalloproteinases
Neoplasms
Developmental Biology
Matrix Metalloproteinase Inhibitors
30 引文 (Scopus)

Meta-analysis of public microarray datasets reveals voltage-gated calcium gene signatures in clinical cancer patients

Wang, C. Y., Lai, M. D., Phan, N. N., Sun, Z. & Lin, Y. C., 七月 6 2015, 於 : PLoS ONE. 10, 7, e0125766.

研究成果: 雜誌貢獻文章

開啟存取
Calcium Channels
Microarrays
meta-analysis
calcium channels
Meta-Analysis
21 引文 (Scopus)

RasGRP1 opposes proliferative EGFR-SOS1-Ras signals and restricts intestinal epithelial cell growth

Depeille, P., Henricks, L. M., Van De Ven, R. A. H., Lemmens, E., Wang, C. Y., Matli, M., Werb, Z., Haigis, K. M., Donner, D., Warren, R. & Roose, J. P., 六月 1 2015, 於 : Nature Cell Biology. 17, 6, p. 804-815 12 p.

研究成果: 雜誌貢獻文章

Epithelial Cells
Growth
Colorectal Neoplasms
Mutation
Epithelium
333 引文 (Scopus)

Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells

Lawson, D. A., Bhakta, N. R., Kessenbrock, K., Prummel, K. D., Yu, Y., Takai, K., Zhou, A., Eyob, H., Balakrishnan, S., Wang, C. Y., Yaswen, P., Goga, A. & Werb, Z., 十月 1 2015, 於 : Nature. 526, 7571, p. 131-135 5 p.

研究成果: 雜誌貢獻文章

Single-Cell Analysis
Stem Cells
Breast Neoplasms
Neoplasm Metastasis
Neoplasms
17 引文 (Scopus)

Therapeutics targeting CD90-integrin-AMPK-CD133 signal axis in liver cancer

Chen, W. C., Chang, Y. S., Hsu, H. P., Yen, M. C., Huang, H. L., Cho, C. Y., Wang, C. Y., Weng, T. Y., Lai, P. T., Chen, C. S., Lin, Y. J. & Lai, M. D., 一月 1 2015, 於 : Oncotarget. 6, 40, p. 42923-42937 15 p.

研究成果: 雜誌貢獻文章

開啟存取
AMP-Activated Protein Kinases
Liver Neoplasms
Integrins
Neoplastic Stem Cells
Neoplasms
16 引文 (Scopus)

The transcriptional repressor ZNF503/Zeppo2 promotes mammary epithelial cell proliferation and enhances cell invasion

Shahi, P., Slorach, E. M., Wang, C. Y., Chou, J., Lu, A., Ruderisch, A. & Werb, Z., 二月 6 2015, 於 : Journal of Biological Chemistry. 290, 6, p. 3803-3813 11 p.

研究成果: 雜誌貢獻文章

開啟存取
Cell proliferation
Breast
Epithelial Cells
Zinc Fingers
Cell Proliferation
2014
10 引文 (Scopus)

A novel cancer therapeutic using thrombospondin 1 in dendritic cells

Weng, T. Y., Huang, S. S., Yen, M. C., Lin, C. C., Chen, Y. L., Lin, C. M., Chen, W. C., Wang, C. Y., Chang, J. Y. & Lai, M. D., 一月 1 2014, 於 : Molecular Therapy. 22, 2, p. 292-302 11 p.

研究成果: 雜誌貢獻文章

開啟存取
Thrombospondin 1
Dendritic Cells
Neoplasms
Small Interfering RNA
Therapeutics
7 引文 (Scopus)

DNA vaccine elicits an efficient antitumor response by targeting the mutant Kras in a transgenic mouse lung cancer model

Weng, T. Y., Yen, M. C., Huang, C. T., Hung, J. J., Chen, Y. L., Chen, W. C., Wang, C. Y., Chang, J. Y. & Lai, M. D., 一月 1 2014, 於 : Gene Therapy. 21, 10, p. 888-896 9 p.

研究成果: 雜誌貢獻文章

開啟存取
DNA Vaccines
Transgenic Mice
Lung Neoplasms
Therapeutic Uses
Neoplasms
12 引文 (Scopus)

Fatty acid metabolic enzyme acyl-CoA thioesterase 8 promotes the development of hepatocellular carcinoma

Hung, Y. U. H., Chan, Y. I. S., Chang, Y. S., Lee, K. T., Hsu, H. P., Yen, M. C., Chen, W. C., Wang, C. Y. & Lai, M. D., 一月 1 2014, 於 : Oncology Reports. 31, 6, p. 2797-2803 7 p.

研究成果: 雜誌貢獻文章

開啟存取
Acyl Coenzyme A
Hepatocellular Carcinoma
Fatty Acids
Enzymes
Nonesterified Fatty Acids
7 引文 (Scopus)

Optimization protein productivity of human interleukin-2 through codon usage, gene copy number and intracellular tRNA concentration in CHO cells

Ou, K. C., Wang, C. Y., Liu, K. T., Chen, Y. L., Chen, Y. C., Lai, M. D. & Yen, M. C., 十一月 14 2014, 於 : Biochemical and Biophysical Research Communications. 454, 2, p. 347-352 6 p.

研究成果: 雜誌貢獻文章

Gene Dosage
CHO Cells
Transfer RNA
Codon
Genes
11 引文 (Scopus)

The novel regulations of MEF2A, CAMKK2, CALM3, and TNNI3 in ventricular hypertrophy induced by arsenic exposure in rats

Phan, N. N., Wang, C. Y. & Lin, Y. C., 十月 3 2014, 於 : Toxicology. 324, p. 123-135 13 p.

研究成果: 雜誌貢獻文章

Arsenic
Hypertrophy
Rats
Cardiomegaly
Skin Neoplasms
2013
5 引文 (Scopus)

An HDAC inhibitor enhances cancer therapeutic efficiency of RNA polymerase III promoter-driven IDO shRNA

Yen, M. C., Weng, T. Y., Chen, Y. L., Lin, C. C., Chen, C. Y., Wang, C. Y., Chao, H. L., Chen, C. S. & Lai, M. D., 六月 1 2013, 於 : Cancer Gene Therapy. 20, 6, p. 351-357 7 p.

研究成果: 雜誌貢獻文章

開啟存取
Indoleamine-Pyrrole 2,3,-Dioxygenase
RNA Polymerase III
Histone Deacetylase Inhibitors
Small Interfering RNA
Neoplasms
2012
10 引文 (Scopus)

Paeoniae radix reduces PDGF-stimulated hepatic stellate cell migration

Kuo, J. J., Wang, C. Y., Lee, T. F., Huang, Y. T. & Lin, Y. L., 三月 8 2012, 於 : Planta Medica. 78, 4, p. 341-348 8 p.

研究成果: 雜誌貢獻文章

Paeonia
Hepatic Stellate Cells
Cell Movement
Collagen
Rubiaceae