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研究成果 1995 2018

  • 1751 引文
  • 21 h-指數
  • 57 文章
  • 1 會議貢獻
  • 1 評論/辯論
篩選
文章
2018
2 引文 (Scopus)

PMA inhibits endothelial cell migration through activating the PKC-δ/Syk/NF-κB-mediated up-regulation of Thy-1

Wen, H. C., Huo, Y. N., Chou, C. M. & Lee, W. S., 十二月 1 2018, 於 : Scientific Reports. 8, 1, 16247.

研究成果: 雜誌貢獻文章

Cell Movement
Acetates
Up-Regulation
Endothelial Cells
phorbol-12-myristate
Endothelial cells
Human Umbilical Vein Endothelial Cells
Progesterone
Up-Regulation
Protein Binding
2017
2 引文 (Scopus)

IRF9-Stat2 Fusion Protein as an Innate Immune Inducer to Activate Mx and Interferon-Stimulated Gene Expression in Zebrafish Larvae

Huang, C. J., Chou, C. M., Lien, H. W., Chu, C. Y., Ho, J. Y., Wu, Y. & Cheng, C. H., 五月 12 2017, (接受/付印) 於 : Marine Biotechnology. p. 1-10 10 p.

研究成果: 雜誌貢獻文章

Zebrafish
interferons
Danio rerio
Interferons
gene expression
2016
24 引文 (Scopus)

Approach to Deliver Two Antioxidant Enzymes with Mesoporous Silica Nanoparticles into Cells

Lin, Y. H., Chen, Y. P., Liu, T. P., Chien, F. C., Chou, C. M., Chen, C. T. & Mou, C. Y., 七月 20 2016, 於 : ACS Applied Materials and Interfaces. 8, 28, p. 17944-17954 11 p.

研究成果: 雜誌貢獻文章

Antioxidants
Silicon Dioxide
Enzymes
Silica
Nanoparticles
34 引文 (Scopus)

Astrocytic GAP43 induced by the TLR4/NF-κB/STAT3 axis attenuates astrogliosis-mediated microglial activation and neurotoxicity

Hung, C. C., Lin, C. H., Chang, H., Wang, C. Y., Lin, S. H., Hsu, P. C., Sun, Y. Y., Lin, T. N., Shie, F. S., Kao, L. S., Chou, C. M. & Lee, Y-H., 二月 10 2016, 於 : Journal of Neuroscience. 36, 6, p. 2027-2043 17 p.

研究成果: 雜誌貢獻文章

GAP-43 Protein
STAT3 Transcription Factor
Excitatory Amino Acid Transporter 2
Astrocytes
Lipopolysaccharides
3 引文 (Scopus)

Novel synthetic benzimidazole-derived oligosaccharide, M3BIM, prevents ex vivo platelet aggregation and in vivo thromboembolism

Yen, T. L., Wu, M. P., Chung, C. L., Yang, W. B., Jayakumar, T., Geraldine, P., Chou, C. M., Chang, C. Y., Lu, W-J. & Sheu, J. R., 二月 17 2016, 於 : Journal of Biomedical Science. 23, 1, 26.

研究成果: 雜誌貢獻文章

Thromboembolism
Platelets
Oligosaccharides
Platelet Aggregation
Collagen
24 引文 (Scopus)

PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress

Kuo, M. L., Lee, M. B. E., Tang, M., Den Besten, W., Hu, S., Sweredoski, M. J., Hess, S., Chou, C. M., Changou, C. A., Su, M., Jia, W., Su, L. & Yen, Y., 一月 6 2016, 於 : Scientific Reports. 6, 18846.

研究成果: 雜誌貢獻文章

Oxidative Stress
Pyrroline Carboxylate Reductases
Fibroblasts
Ribonucleotide Reductases
Foreskin
Peroxynitrous Acid
Cyclooxygenase 2
Superoxide Dismutase
Skin
HIV

Zebrafish cyclin Dx is required for development of motor neuron progenitors, and its expression is regulated by hypoxia-inducible factor 2α

Lien, H. W., Yuan, R. Y., Chou, C. M., Chen, Y. C., Hung, C. C., Hu, C. H., Hwang, S. P. L., Hwang, P. P., Shen, C. N., Chen, C. L., Cheng, C. H. & Huang, C. J., 六月 21 2016, 於 : Scientific Reports. 6, 28297.

研究成果: 雜誌貢獻文章

Cyclins
Motor Neurons
Zebrafish
Cyclin D3
Cyclin D2
2015

Activation of MEK2 is sufficient to induce skin papilloma formation in transgenic zebrafish Application of Zebrafish in Biomedical Research

Chou, C. M., Chen, Y. C., Su, S., Chen, G. D., Huang, K. Y., Lien, H. W., Huang, C. J. & Cheng, C. H., 十一月 17 2015, 於 : Journal of Biomedical Science. 22, 1, 102.

研究成果: 雜誌貢獻文章

Papilloma
Zebrafish
Biomedical Research
Skin
Chemical activation
22 引文 (Scopus)
Silicon Dioxide
Silica
Nanoparticles
Proteins
Macrophages
17 引文 (Scopus)
Hydrogels
stem cells
Strontium
teeth
Stem cells
22 引文 (Scopus)

Repositioning antipsychotic chlorpromazine for treating colorectal cancer by inhibiting sirtuin 1

Lee, W. Y., Lee, W. T., Cheng, C. H., Chen, K. C., Chou, C. M., Chung, C. H., Sun, M. S., Cheng, H. W., Ho, M. N. & Lin, C. W., 2015, 於 : Oncotarget. 6, 29, p. 27580-27595 16 p.

研究成果: 雜誌貢獻文章

Sirtuin 1
Chlorpromazine
Antipsychotic Agents
Colorectal Neoplasms
JNK Mitogen-Activated Protein Kinases
9 引文 (Scopus)

RPS12 increases the invasiveness in cervical cancer activated by c-Myc and inhibited by the dietary flavonoids luteolin and quercetin

Lin, C. W., Lai, G. M., Chen, K. C., Lin, T. H., Fan, J. J., Hsu, R. L., Chou, C. M., Lin, C. M., Kandaswami, C. C., Lee, M. T. & Cheng, C. H., 十二月 1 2015, 於 : Journal of Functional Foods. 19, p. 236-247 12 p.

研究成果: 雜誌貢獻文章

Luteolin
uterine cervical neoplasms
luteolin
Quercetin
Flavonoids
11 引文 (Scopus)

The novel ribonucleotide reductase inhibitor COH29 inhibits DNA repair in vitros

Chen, M. C., Zhou, B., Zhang, K., Yuan, Y. C., Un, F., Hu, S., Chou, C. M., Chen, C. H., Wu, J., Wang, Y., Liu, X., Smith, D. L., Li, H., Liu, Z., Warden, C. D., Su, L., Malkas, L. H., Chung, Y. M., Hu, M. C. T. & Yen, Y., 六月 1 2015, 於 : Molecular Pharmacology. 87, 6, p. 996-1005 10 p.

研究成果: 雜誌貢獻文章

Ribonucleotide Reductases
DNA Repair
DNA Damage
gemcitabine
Deoxyribonucleotides
2014
9 引文 (Scopus)

Differential regulation of Tetraodon nigroviridis Mx gene promoter activity by constitutively-active forms of STAT1, STAT2, and IRF9

Cheng, C. H., Chou, C. M., Chu, C. Y., Chen, G. D., Lien, H. W., Hwang, P. P., Chang, M. S. & Huang, C. J., 2014, 於 : Fish and Shellfish Immunology. 38, 1, p. 230-243 14 p.

研究成果: 雜誌貢獻文章

interferons
Interferons
Genes
promoter regions
Interferon-gamma
11 引文 (Scopus)

Optimal fluid flow enhanced mineralization of MG-63 cells in porous chitosan scaffold

Su, W. T., Wang, Y. T. & Chou, C. M., 2014, 於 : Journal of the Taiwan Institute of Chemical Engineers. 45, 4, p. 1111-1118 8 p.

研究成果: 雜誌貢獻文章

Chitosan
Scaffolds
Flow of fluids
Osteoblasts
Flow rate
6 引文 (Scopus)

The Nogo-C2/Nogo receptor complex regulates the morphogenesis of zebrafish lateral line primordium through modulating the expression of dkk1b, a Wnt signal inhibitor

Han, H. W., Chou, C. M., Chu, C. Y., Cheng, C. H., Yang, C. H., Hung, C. C., Hwang, P. P., Lee, S. J., Liao, Y. F. & Huang, C. J., 一月 21 2014, 於 : PLoS One. 9, 1, e86345.

研究成果: 雜誌貢獻文章

Zebrafish
Danio rerio
Morphogenesis
morphogenesis
Fishes
2013
95 引文 (Scopus)

A new strategy for intracellular delivery of enzyme using mesoporous silica nanoparticles: Superoxide dismutase

Chen, Y. P., Chen, C. T., Hung, Y., Chou, C. M., Liu, T. P., Liang, M. R., Chen, C. T. & Mou, C. Y., 一月 30 2013, 於 : Journal of the American Chemical Society. 135, 4, p. 1516-1523 8 p.

研究成果: 雜誌貢獻文章

Trans-Activators
Silicon Dioxide
Nanoparticles
Superoxide Dismutase
Enzymes
2012
3 引文 (Scopus)
Fractals
Tumor Microenvironment
Anomalous Diffusion
Cell adhesion
Diffusion Model
2011
4 引文 (Scopus)

Denervation dynamically regulates integrin α7 signaling pathways and microscopic structures in rats

Tsai, F-C., Pai, M. H., Chiu, C. C., Chou, C. M. & Hsieh, M-S., 一月 2011, 於 : Journal of Trauma - Injury, Infection and Critical Care. 70, 1, p. 220-227 8 p.

研究成果: 雜誌貢獻文章

Denervation
Integrins
Skeletal Muscle
Transmission Electron Microscopy
Electron Scanning Microscopy
6 引文 (Scopus)

Downregulation of the integrin αv signaling pathway in uterine leiomyomas

Tsai, F-C., Liu, W-M., Pai, M-H., Hsieh, M-S., Lin, J. Y. & Chou, C-M., 三月 2011, 於 : Gynecologic and Obstetric Investigation. 71, 2, p. 129-135 7 p.

研究成果: 雜誌貢獻文章

Leiomyoma
Integrins
Down-Regulation
Apoptosis
Survival
35 引文 (Scopus)

Identification and functional analysis of an ovarian form of the egg activation factor phospholipase C zeta (PLCζ) in pufferfish

Coward, K., Ponting, C. P., Zhang, N., Young, C., Huang, C. J., Chou, C. M., Kashir, J., Fissore, R. A. & Parrington, J., 一月 2011, 於 : Molecular Reproduction and Development. 78, 1, p. 48-56 9 p.

研究成果: 雜誌貢獻文章

Tetraodontiformes
Type C Phospholipases
Takifugu
Oryzias
Ovum
2010
14 引文 (Scopus)

Comparison between neurectomy and botulinum toxin A injection for denervated skeletal muscle

Tsai, F-C., Hsieh, M-S. & Chou, C. M., 八月 1 2010, 於 : Journal of Neurotrauma. 27, 8, p. 1509-1516 8 p.

研究成果: 雜誌貢獻文章

Type A Botulinum Toxins
Skeletal Muscle
Injections
Muscles
Apoptosis Inducing Factor
7 引文 (Scopus)

Expression and characterization of a constitutively active STAT6 from Tetraodon

Sung, S. C., Cheng, C. H., Chou, C. M., Chu, C. Y., Chen, G. D., Hwang, P. P., Huang, F. L. & Huang, C. J., 五月 2010, 於 : Fish and Shellfish Immunology. 28, 5-6, p. 819-828 10 p.

研究成果: 雜誌貢獻文章

interleukin-4
exons
Exons
Phosphorylation
Genes
23 引文 (Scopus)

Glucocorticoid protection of oligodendrocytes against excitotoxin involving hypoxia-inducible factor-1α in a cell-type-specific manner

Sun, Y. Y., Wang, C. Y., Hsu, M. F., Juan, S. H., Chang, C. Y., Chou, C. M., Yang, L. Y., Hung, K. S., Xu, J., Lee, Y-H. & Hsu, C-Y., 七月 14 2010, 於 : Journal of Neuroscience. 30, 28, p. 9621-9630 10 p.

研究成果: 雜誌貢獻文章

Hypoxia-Inducible Factor 1
Oligodendroglia
Neurotoxins
Erythropoietin
Glucocorticoid Receptors
13 引文 (Scopus)
Adiponectin
Cyclooxygenase 2
Hepatocytes
Iron
Wounds and Injuries
4 引文 (Scopus)
Nonmuscle Myosin Type IIA
FSH Receptors
Sertoli Cells
Type C Phospholipases
Myosins
2009
23 引文 (Scopus)

Knockdown of the aryl hydrocarbon receptor attenuates excitotoxicity and enhances NMDA-induced BDNF expression in cortical neurons

Lin, C. H., Chen, C. C., Chou, C. M., Wang, C. Y., Hung, C. C., Chen, J. Y., Chang, H. W., Chen, Y. C., Yeh, G. C. & Lee, Y-H., 十一月 2009, 於 : Journal of Neurochemistry. 111, 3, p. 777-789 13 p.

研究成果: 雜誌貢獻文章

Aryl Hydrocarbon Receptors
Brain-Derived Neurotrophic Factor
N-Methylaspartate
Neurons
N-Methyl-D-Aspartate Receptors
2008
7 引文 (Scopus)

Expression and characterization of two STAT isoforms from Sf9 cells

Yeh, M. S., Cheng, C. H., Chou, C. M., Hsu, Y. L., Chu, C. Y., Chen, G. D., Chen, S. T., Chen, G. C. & Huang, C. J., 2008, 於 : Developmental and Comparative Immunology. 32, 7, p. 814-824 11 p.

研究成果: 雜誌貢獻文章

Sf9 Cells
Protein Isoforms
Baculoviridae
Drosophila
Alternative Splicing
34 引文 (Scopus)

Neuronal activity enhances aryl hydrocarbon receptor-mediated gene expression and dioxin neurotoxicity in cortical neurons

Lin, C. H., Juan, S. H., Wang, C. Y., Sun, Y. Y., Chou, C. M., Chang, S. F., Hu, S. Y., Lee, W. S. & Lee, Y-H., 三月 2008, 於 : Journal of Neurochemistry. 104, 5, p. 1415-1429 15 p.

研究成果: 雜誌貢獻文章

Aryl Hydrocarbon Receptors
Dioxins
Gene expression
Neurons
Gene Expression
17 引文 (Scopus)
Hypertrophy
Skeletal Muscle
Gait
Lipectomy
Electromyography
2006
69 引文 (Scopus)

Effects of cadmium on structure and enzymatic activity of Cu,Zn-SOD and oxidative status in neural cells

Huang, Y-H., Shih, C-M., Huang, C. J., Lin, C-M., Chou, C-M., Tsai, M. L., Liu, T. P., Chiu, J. F. & Chen, C-T., 六月 1 2006, 於 : Journal of Cellular Biochemistry. 98, 3, p. 577-589 13 p.

研究成果: 雜誌貢獻文章

Cadmium
Proteins
Enzyme activity
Amyotrophic Lateral Sclerosis
Enzymes
7 引文 (Scopus)

Expression and characterization of a brain-specific protein kinase BSK146 from zebrafish

Chou, C. M., Chen, Y. C., Lee, M. T., Chen, G. D., Lu, I. C., Chen, S. T. & Huang, C. J., 二月 17 2006, 於 : Biochemical and Biophysical Research Communications. 340, 3, p. 767-775 9 p.

研究成果: 雜誌貢獻文章

EphA5 Receptor
Zebrafish
Protein Kinases
Brain
Rhombencephalon
5 引文 (Scopus)

Requirement of nuclear localization and transcriptional activity of p53 for its targeting to the yolk syncytial layer (YSL) nuclei in zebrafish embryo and its use for apoptosis assay

Chen, G. D., Chou, C. M., Hwang, S. P. L., Wang, F. F., Chen, Y. C., Hung, C. C., Chen, J. Y. & Huang, C. J., 五月 26 2006, 於 : Biochemical and Biophysical Research Communications. 344, 1, p. 272-282 11 p.

研究成果: 雜誌貢獻文章

Zebrafish
Assays
Fusion reactions
Embryonic Structures
Karyopherins
2004
62 引文 (Scopus)

Characterization of two mosquito STATs, AaSTAT and CtSTAT: Differential regulation of tyrosine phosphorylation and DNA binding activity by lipopolysaccharide treatment and by Japanese encephalitis virus infection

Lin, C. C., Chou, C. M., Hsu, Y. L., Lien, J. C., Wang, Y. M., Chen, S. T., Tsai, S. C., Hsiao, P. W. & Huang, C. J., 一月 30 2004, 於 : Journal of Biological Chemistry. 279, 5, p. 3308-3317 10 p.

研究成果: 雜誌貢獻文章

Japanese Encephalitis Virus
Phosphorylation
Culicidae
Viruses
Tyrosine
20 引文 (Scopus)

Early detection of antibodies against various structural proteins of the SARS-associated coronavirus in SARS patients

Wu, H. S., Hsieh, Y. C., Su, I. J., Lin, T. H., Chiu, S. C., Hsu, Y. F., Lin, J. H., Wang, M. C., Chen, J. Y., Hsiao, P. W., Chang, G. D., Wang, A. H. J., Ting, H. W., Chou, C. M. & Huang, C. J., 2004, 於 : Journal of Biomedical Science. 11, 1, p. 117-126 10 p.

研究成果: 雜誌貢獻文章

Severe Acute Respiratory Syndrome
Coronavirus
Recombinant Proteins
Nucleocapsid
Antibodies
2 引文 (Scopus)

Identification of 5′-upstream region of pufferfish ribosomal protein L29 gene as a strong constitutive promoter to drive GFP expression in zebrafish

Chang, M. H., Chou, C. M., Hsieh, Y. C., Lu, I. C., Devi, M. K. N., Chang, J. P., Kuo, T. F. & Huang, C. J., 一月 30 2004, 於 : Biochemical and Biophysical Research Communications. 314, 1, p. 249-258 10 p.

研究成果: 雜誌貢獻文章

Tetraodontiformes
Transcription Initiation Site
COS Cells
Zebrafish
Luciferases
22 引文 (Scopus)

Purification and Cloning of an Endogenous Protein Inhibitor of Carp Nephrosin, an Astacin Metalloproteinase

Tsai, P. L., Chen, C. H., Huang, C. J., Chou, C-M. & Chang, G. D., 三月 19 2004, 於 : Journal of Biological Chemistry. 279, 12, p. 11146-11155 10 p.

研究成果: 雜誌貢獻文章

Carps
Cloning
Metalloproteases
Purification
Organism Cloning
6 引文 (Scopus)

Zebrafish heparin-binding neurotrophic factor enhances neurite outgrowth during its development

Chang, M. H., Huang, C. J., Hwang, S. P. L., Lu, I. C., Lin, C. M., Kuo, T. F. & Chou, C. M., 八月 20 2004, 於 : Biochemical and Biophysical Research Communications. 321, 2, p. 502-509 8 p.

研究成果: 雜誌貢獻文章

Zebrafish
Embryonic Development
Tissue
Neuronal Outgrowth
pleiotrophin
2003
14 引文 (Scopus)

Cloning of zebrafish BAD, a BH3-only proapoptotic protein, whose overexpression leads to apoptosis in COS-1 cells and zebrafish embryos

Hsieh, Y. C., Chang, M. S., Chen, J. Y., Yen, J. J. Y., Lu, I. C., Chou, C. M. & Huang, C. J., 五月 16 2003, 於 : Biochemical and Biophysical Research Communications. 304, 4, p. 667-675 9 p.

研究成果: 雜誌貢獻文章

Cloning
COS Cells
Zebrafish
Organism Cloning
Embryonic Structures
21 引文 (Scopus)

Genomic structure, expression and characterization of a STAT5 homologue from pufferfish (Tetraodon fluviatilis)

Sung, S. C., Fan, T. J., Chou, C. M., Leu, J. H., Hsu, Y. L., Chen, S. T., Hsieh, Y. C. & Huang, C. J., 2003, 於 : European Journal of Biochemistry. 270, 2, p. 239-252 14 p.

研究成果: 雜誌貢獻文章

STAT5 Transcription Factor
Tetraodontiformes
Genes
Fusion reactions
Caseins
2002
88 引文 (Scopus)

Identification of a nucleocapsid protein (VP35) gene of shrimp white spot syndrome virus and characterization of the motif important for targeting VP35 to the nuclei of transfected insect cells

Chen, L. L., Leu, J. H., Huang, C. J., Chou, C. M., Chen, S. M., Wang, C. H., Lo, C. F. & Kou, G. H., 2002, 於 : Virology. 293, 1, p. 44-53 10 p.

研究成果: 雜誌貢獻文章

White spot syndrome virus 1
Nucleocapsid Proteins
Insects
Open Reading Frames
Nuclear Localization Signals
2000
41 引文 (Scopus)

Complete genomic organization and promoter analysis of the round-spotted pufferfish JAK1, JAK2, JAK3, and TYK2 genes

Leu, J. H., Yan, S. J., Lee, T. F., Chou, C. M., Chen, S. T., Hwang, P. P., Chou, C. K. & Huang, C. J., 2000, 於 : DNA and Cell Biology. 19, 7, p. 431-446 16 p.

研究成果: 雜誌貢獻文章

Tetraodontiformes
Genes
Exons
Genetic Promoter Regions
Introns
4 引文 (Scopus)

Genomic organization and the promoter region of the round-spotted pufferfish (Tetraodon fluviatilis) CDC37 gene

Tsai, S. C., Leu, J. H., Chou, C. M., Yeh, M. S., Huang, F. L. & Huang, C. J., 十一月 15 2000, 於 : Biochimica et Biophysica Acta - Gene Structure and Expression. 1494, 1-2, p. 144-148 5 p.

研究成果: 雜誌貢獻文章

Tetraodontiformes
Genetic Promoter Regions
Genes
Exons
Chloramphenicol O-Acetyltransferase
68 引文 (Scopus)

Identification and characterization of a shrimp white spot syndrome virus (WSSV) gene that encodes a novel chimeric polypeptide of cellular-type thymidine kinase and thymidylate kinase

Tsai, M. F., Yu, H. T., Tzeng, H. F., Leu, J. H., Chou, C. M., Huang, C. J., Wang, C. H., Lin, J. Y., Kou, G. H. & Lo, C. F., 十一月 10 2000, 於 : Virology. 277, 1, p. 100-110 11 p.

研究成果: 雜誌貢獻文章

dTMP kinase
White spot syndrome virus 1
Thymidine Kinase
Peptides
Genes
68 引文 (Scopus)

Transcriptional analysis of the ribonucleotide reductase genes of shrimp white spot syndrome virus

Tsai, M. F., Lo, C. F., Van Hulten, M. C. W., Tzeng, H. F., Chou, C. M., Huang, C. J., Wang, C. H., Lin, J. Y., Vlak, J. M. & Kou, G. H., 十一月 10 2000, 於 : Virology. 277, 1, p. 92-99 8 p.

研究成果: 雜誌貢獻文章

White spot syndrome virus 1
Ribonucleotide Reductases
Nimaviridae
Northern Blotting
Genes
1998
6 引文 (Scopus)

Isolation and identification of novel protein kinase genes from the round-spotted pufferfish (Tetraodon fluviatilis) genomic DNA

Chou, C. M., Lin, W. C., Leu, J. H., Su, T. L., Chou, C. K. & Huang, C. J., 1998, 於 : Journal of Biomedical Science. 5, 2, p. 127-134 8 p.

研究成果: 雜誌貢獻文章

Tetraodontiformes
Protein Kinases
Genes
DNA
Introns
15 引文 (Scopus)

The small subunit ribosomal RNA gene sequence of Pleistophora anguillarum and the use of PCR primers for diagnostic detection of the parasite

Hung, H. W., Lo, C. F., Tseng, C. C., Peng, S. E., Chou, C. M. & Kou, G. H., 九月 1998, 於 : Journal of Eukaryotic Microbiology. 45, 5, p. 556-560 5 p.

研究成果: 雜誌貢獻文章

Pleistophora
Small Ribosome Subunits
Eels
Microsporidia
eel