每年研究成果
研究成果
2019
A novel 2-aminobenzimidazole-based compound Jzu 17 exhibits anti-angiogenesis effects by targeting VEGFR-2 signalling
Lien, J. C., Chung, C. L., Huang, T. F., Chang, T. C., Chen, K. C., Gao, G. Y., Hsu, M. J. & Huang, S. W., 十月 1 2019, 於 : British Journal of Pharmacology. 176, 20, p. 4034-4049 16 p.研究成果: 雜誌貢獻 › 文章
Autophagosome accumulation-mediated ATP energy deprivation induced by penfluridol triggers nonapoptotic cell death of lung cancer via activating unfolded protein response
Hung, W. Y., Chang, J. H., Cheng, Y., Cheng, G. Z., Huang, H. C., Hsiao, M., Chung, C. L., Lee, W. J. & Chien, M. H., 八月 1 2019, 於 : Cell Death and Disease. 10, 8, 538.研究成果: 雜誌貢獻 › 文章
開啟存取
1
引文
斯高帕斯（Scopus）
Defining risk of general surgery in patients with chronic obstructive pulmonary diseases
Lin, C. S., Chen, C. Y., Yeh, C. C., Chung, C. L., Chen, T. L. & Liao, C. C., 二月 1 2019, 於 : QJM : monthly journal of the Association of Physicians. 112, 2, p. 107-113 7 p.研究成果: 雜誌貢獻 › 文章
2
引文
斯高帕斯（Scopus）
Endothelin-1 Induces Mesothelial Mesenchymal Transition and Correlates with Pleural Fibrosis in Tuberculous Pleural Effusions
Wu, Z-H., Tsai, J-H., Hsieh, C-Y., Chen, W-L. & Chung, C-L., 三月 29 2019, 於 : Journal of Clinical Medicine. 8, 4, 426.研究成果: 雜誌貢獻 › 文章
Thrombin upregulates PAI-1 and mesothelial–mesenchymal transition through PAR-1 and contributes to tuberculous pleural fibrosis
Hsieh, C. Y., Sheu, J. R., Yang, C. H., Chen, W. L., Tsai, J. H. & Chung, C. L., 十月 2 2019, 於 : International Journal of Molecular Sciences. 20, 20, 5076.研究成果: 雜誌貢獻 › 文章
開啟存取
2018
Analysis of Titin in Red and White Muscles: Crucial Role on Muscle Contractions Using a Fish Model
Wu, M. P., Chang, N. C., Chung, C. L., Chiu, W. C., Hsu, C. C., Chen, H. M., Sheu, J. R., Jayakumar, T., Chou, D. S. & Fong, T. H., 十一月 18 2018, 於 : BioMed Research International. 2018, p. 5816875 11 p., 5816875.研究成果: 雜誌貢獻 › 文章
An Antithrombotic Strategy by Targeting Phospholipase D in Human Platelets
Lu, W. J., Chung, C. L., Chen, R. J., Huang, L. T., Lien, L. M., Chang, C. C., Lin, K. H. & Sheu, J. R., 十一月 14 2018, 於 : Journal of Clinical Medicine. 7, 11研究成果: 雜誌貢獻 › 文章
Decreased risk of pneumonia in stroke patients receiving acupuncture: A nationwide matched-pair retrospective cohort study
Chang, C. C., Chen, T. L., Lin, C. S., Chung, C. L., Yeh, C. C., Hu, C. J., Lane, H. L., Liao, C. C. & Shih, C. C., 五月 1 2018, 於 : PLoS One. 13, 5, e0196094.研究成果: 雜誌貢獻 › 文章
開啟存取
Effect of influenza vaccination against postoperative pneumonia and mortality for geriatric patients receiving major surgery: A nationwide matched study
Liu, W. C., Lin, C. S., Yeh, C. C., Wu, H. Y., Lee, Y. J., Chung, C. L., Cherng, Y. G., Chen, T. L. & Liao, C. C., 三月 1 2018, 於 : Journal of Infectious Diseases. 217, 5, p. 816-826 11 p.研究成果: 雜誌貢獻 › 文章
4
引文
斯高帕斯（Scopus）
Leukocyte Cell-Derived Chemotaxin 2 Retards Non-Small Cell Lung Cancer Progression Through Antagonizing MET and EGFR Activities
Hung, W. Y., Chang, J. H., Cheng, Y., Chen, C. K., Chen, J. Q., Hua, K. T., Cheng, C. W., Hsiao, M., Chung, C. L., Lee, W. J. & Chien, M. H., 一月 1 2018, 於 : Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 51, 1, p. 337-355 19 p.研究成果: 雜誌貢獻 › 文章
3
引文
斯高帕斯（Scopus）
Lipoteichoic acid upregulates plasminogen activator inhibitor-1 expression in parapneumonic effusions
Lee, K. L., Chen, W. L., Chen, R. J., Lai, K. S. & Chung, C. L., 一月 1 2018, 於 : Respirology. 23, 1, p. 89-95 7 p.研究成果: 雜誌貢獻 › 文章
6
引文
斯高帕斯（Scopus）
Lupus pneumonitis presenting with high titre of anti-ro antibody
Chen, M. C., Wu, Y. L., Lee, K. L., Lai, K. S. & Chung, C. L., 一月 1 2018, 於 : Respirology Case Reports. 6, 1, e00280.研究成果: 雜誌貢獻 › 文章
Neuroprotective effects of platonin, a therapeutic immunomodulating medicine, on traumatic brain injury in mice after controlled cortical impact
Yen, T. L., Chang, C. C., Chung, C. L., Ko, W. C., Yang, C. H. & Hsieh, C. Y., 四月 6 2018, 於 : International Journal of Molecular Sciences. 19, 4, 1100.研究成果: 雜誌貢獻 › 文章
3
引文
斯高帕斯（Scopus）
Novel therapeutic agent against platelet activation in vitro and arterial thrombosis in vivo by morin hydrate
Hsia, C. W., Wu, M. P., Velusamy, M., Hsia, C. H., Chou, D. S., Tsai, C. L., Hsu, C. Y., Jayakumar, T., Chung, C. L. & Sheu, J. R., 八月 13 2018, 於 : International Journal of Molecular Sciences. 19, 8, 2386.研究成果: 雜誌貢獻 › 文章
2
引文
斯高帕斯（Scopus）
Structure-antiplatelet activity relationships of novel ruthenium (ii) complexes: Investigation of its molecular targets
Hsia, C. H., Jayakumar, T., Sheu, J. R., Tsao, S. Y., Velusamy, M., Hsia, C. W., Chou, D. S., Chang, C. C., Chung, C. L., Khamrang, T. & Lin, K. C., 二月 22 2018, 於 : Molecules. 23, 2, 477.研究成果: 雜誌貢獻 › 文章
3
引文
斯高帕斯（Scopus）
2017
Brain metastases in patients with non-small cell lung cancer: the role of mutated-EGFRs with an exon 19 deletion or L858R point mutation in cancer cell dissemination
Hsiao, S-H., Chou, Y-T., Lin, S-E., Hsu, R-C., Chung, C-L., Kao, Y-R., Liu, H. E. & Wu, C-W., 八月 8 2017, 於 : Oncotarget. 8, 32, p. 53405-53418 14 p.研究成果: 雜誌貢獻 › 文章
Diabetes risks and outcomes in chronic obstructive pulmonary disease patients: Two nationwide population-based retrospective cohort studies
Lin, C. S., Liu, C. C., Yeh, C. C., Chang, Y. C., Chung, C. L., Lane, H. L., Shih, C. C., Chen, T. L. & Liao, C. C., 2017, 於 : PLoS One. 12, 8, p. e0181815研究成果: 雜誌貢獻 › 文章
10
引文
斯高帕斯（Scopus）
Risk of stroke and post-stroke adverse events in patients with exacerbations of chronic obstructive pulmonary disease
Lin, C-S., Shih, C. C., Yeh, C. C., Hu, C-J., Chung, C-L., Chen, T-L. & Liao, C-C., 一月 1 2017, 於 : PLoS One. 12, 1, e0169429.研究成果: 雜誌貢獻 › 文章
8
引文
斯高帕斯（Scopus）
Suppression of reactive oxygen species-mediated ERK and JNK activation sensitizes dihydromyricetin-induced mitochondrial apoptosis in human non-small cell lung cancer
Kao, S. J., Lee, W. J., Chang, J. H., Chow, J. M., Chung, C. L., Hung, W. Y. & Chien, M. H., 四月 1 2017, 於 : Environmental Toxicology. 32, 4, p. 1426-1438研究成果: 雜誌貢獻 › 文章
24
引文
斯高帕斯（Scopus）
2016
Novel synthetic benzimidazole-derived oligosaccharide, M3BIM, prevents ex vivo platelet aggregation and in vivo thromboembolism
Yen, T. L., Wu, M. P., Chung, C. L., Yang, W. B., Jayakumar, T., Geraldine, P., Chou, C. M., Chang, C. Y., Lu, W-J. & Sheu, J. R., 二月 17 2016, 於 : Journal of Biomedical Science. 23, 1, 26.研究成果: 雜誌貢獻 › 文章
3
引文
斯高帕斯（Scopus）
Postoperative Adverse Outcomes in Patients With Asthma: A Nationwide Population-based Cohort Study
Lin, C-S., Chang, C-C., Yeh, C. C., Chung, C. L., Chen, T-L. & Liao, C-C., 一月 2016, 於 : Medicine (United States). 95, 3, p. e2548研究成果: 雜誌貢獻 › 文章
4
引文
斯高帕斯（Scopus）
2015
Adverse outcomes after non-chest surgeries in patients with pulmonary tuberculosis: A nationwide study
Ke, C. C., Lin, C-S., Yeh, C. C., Chung, C-L., Hung, C. J., Liao, C-C., Chen, T-L. & Hozbor, D. F., 七月 14 2015, 於 : PLoS One. 10, 7, e0133064.研究成果: 雜誌貢獻 › 文章
1
引文
斯高帕斯（Scopus）
Hinokitiol Negatively Regulates Immune Responses through Cell Cycle Arrest in Concanavalin A-Activated Lymphocytes
Chung, C. L., Leung, K. W., Lu, W-J., Yen, T. L., He, C. F., Sheu, J. R., Lin, K. H. & Lien, L. M., 2015, 於 : Evidence-based Complementary and Alternative Medicine. 2015, 595824.研究成果: 雜誌貢獻 › 文章
3
引文
斯高帕斯（Scopus）
Inhaled pharmacotherapy and stroke risk in patients with chronic obstructive pulmonary disease: A nationwide population based study using two-stage approach
Lin, H. W., Chung, C. L., Lin, Y. S., Yu, C. M., Lee, C-N. & Bien, M. Y., 七月 9 2015, 於 : PLoS One. 10, 7, e0130102.研究成果: 雜誌貢獻 › 文章
10
引文
斯高帕斯（Scopus）
Mycobacterium tuberculosis upregulates TNF-α Expression via TLR2/ERK signaling and induces MMP-1 and MMP-9 production in human pleural mesothelial cells
Chen, W. L., Sheu, J. R., Chen, R. J., Hsiao, S. H., Hsiao, C. J., Chou, Y. C., Chung, C. L. & Hsiao, G., 九月 14 2015, 於 : PLoS One. 10, 9, e0137979.研究成果: 雜誌貢獻 › 文章
17
引文
斯高帕斯（Scopus）
Proper Diagnostic Differentiation of Atypical Adenomatous Hyperplasia and Pulmonary Adenocarcinoma
Lai, K. S., Lin, S-E., Zeng, M-S., Lee, K-L., Hsiao, S-H. & Chung, C-L., 八月 1 2015, 於 : 胸腔醫學. 30, 4, p. 224-231 8 p.研究成果: 雜誌貢獻 › 文章
Pulmonary Squamous Cell Carcinoma Harboring EGFR Exon 19 Mutation Responded Dramatically to EGFR-TKI-A Case Report
研究成果: 雜誌貢獻 › 文章
VEGF correlates with inflammation and fibrosis in tuberculous pleural effusion
Bien, M. Y., Wu, M-P., Chen, W. L. & Chung, C. L., 2015, 於 : Scientific World Journal. 2015, 417124.研究成果: 雜誌貢獻 › 文章
3
引文
斯高帕斯（Scopus）
2014
Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption
Hsiao, C. J., Hsiao, G., Chen, W. L., Wang, S. W., Chiang, C. P., Liu, L. Y., Guh, J. H., Li, Z-H. & Chung, C. L., 四月 25 2014, 於 : Journal of Natural Products. 77, 4, p. 758-765 8 p.研究成果: 雜誌貢獻 › 文章
35
引文
斯高帕斯（Scopus）
Histone deacetylase inhibitor impairs plasminogen activator inhibitor-1 expression via inhibiting TNF-α-activated MAPK/AP-1 signaling cascade
Chen, W. L., Sheu, J. R., Hsiao, C. J., Hsiao, S. H., Chung, C. L. & Hsiao, G., 2014, 於 : BioMed Research International. 2014, 231012.研究成果: 雜誌貢獻 › 文章
11
引文
斯高帕斯（Scopus）
Multidrug resistance protein 4 (MRP4/ABCC4) regulates thrombus formation in vitro and in vivo
Lien, L. M., Chen, Z. C., Chung, C. L., Yen, T. L., Chiu, H. C., Chou, D. S., Huang, S. Y., Sheu, J. R., Lu, W-J. & Lin, K. H., 八月 15 2014, 於 : European Journal of Pharmacology. 737, p. 159-167 9 p.研究成果: 雜誌貢獻 › 文章
15
引文
斯高帕斯（Scopus）
2013
Brazilin isolated from Caesalpinia sappan L. acts as a novel collagen receptor agonist in human platelets
Chang, Y., Huang, S. K. H., Lu, W. J., Chung, C. L., Chen, W. L., Lu, S. H., Lin, K. H. & Sheu, J. R., 一月 25 2013, 於 : Journal of Biomedical Science. p. 4 1 p.研究成果: 雜誌貢獻 › 文章
8
引文
斯高帕斯（Scopus）
Clinical Importance of Angiogenic Cytokines, Fibrinolytic Activity and Effusion Size in Parapneumonic Effusions
Chung, C. L., Hsiao, S. H., Hsiao, G., Sheu, J. R., Chen, W. L. & Chang, S. C., 一月 7 2013, 於 : PLoS One. 8, 1, e53169.研究成果: 雜誌貢獻 › 文章
8
引文
斯高帕斯（Scopus）
Distinct clinical outcomes of non-small cell lung cancer patients with Epidermal Growth Factor Receptor (EGFR) mutations treated with EGFR tyrosine kinase inhibitors: Non-responders versus responders
Hsiao, S. H., Liu, H. E., Lee, H. L., Lin, C. L., Chen, W. Y., Wu, Z. H., Lin, S. E., Chiang, L. L. & Chung, C. L., 十二月 23 2013, 於 : PLoS One. 8, 12, e83266.研究成果: 雜誌貢獻 › 文章
8
引文
斯高帕斯（Scopus）
Hinokitiol inhibits platelet activation ex vivo and thrombus formation in vivo
Lin, K. H., Kuo, J. R., Lu, W-J., Chung, C. L., Chou, D. S., Huang, S. Y., Lee, H. C. & Sheu, J. R., 五月 15 2013, 於 : Biochemical Pharmacology. 85, 10, p. 1478-1485 8 p.研究成果: 雜誌貢獻 › 文章
27
引文
斯高帕斯（Scopus）
Histological subtype and smoking status, but not gender, are associated with epidermal growth factor receptor mutations in non-small‑cell lung cancer
Hsiao, S. H., Lin, S-E., Chou, Y. T., Wang, J-L., Chung, C-L., Yu, M-C., Fang, C-L., Lee, H. L., Chiang, L-L., Liu, H-E. & Wu, C. W., 十二月 23 2013, 於 : Molecular and Clinical Oncology. 2, p. 252-258 7 p.研究成果: 雜誌貢獻 › 文章
檔案
6
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(Pure)
Identification of subgroup patients with stage IIIB/IV non-small cell lung cancer at higher risk for brain metastases
Hsiao, S. H., Chung, C. L., Chou, Y. T., Lee, H. L., Lin, S. E. & Liu, H. E., 十一月 2013, 於 : Lung Cancer. 82, 2, p. 319-323 5 p.研究成果: 雜誌貢獻 › 文章
17
引文
斯高帕斯（Scopus）
Impact of epidermal growth factor receptor mutations on intracranial treatment response and survival after brain metastases in lung adenocarcinoma patients
Hsiao, S. H., Lin, H. C., Chou, Y. T., Lin, S. E., Kuo, C. C., Yu, M. C. & Chung, C. L., 九月 2013, 於 : Lung Cancer. 81, 3, p. 455-461 7 p.研究成果: 雜誌貢獻 › 文章
31
引文
斯高帕斯（Scopus）
Mechanisms of andrographolide-induced platelet apoptosis in human platelets: Regulatory roles of the extrinsic apoptotic pathway
Lien, L-M., Su, C. C., Hsu, W. H., Lu, W-J., Chung, C-L., Yen, T. L., Chiu, H. C., Sheu, J-R. & Lin, K. H., 2013, 於 : Phytotherapy Research. 27, 11, p. 1671-1677 7 p.研究成果: 雜誌貢獻 › 文章
24
引文
斯高帕斯（Scopus）
Suitability of computed tomography-guided biopsy specimens for subtyping and genotyping of non-small-cell lung cancer
Hsiao, S. H., Chung, C. L., Lee, C-M., Chen, W. Y., Chou, Y. T., Wu, Z. H., Chen, Y. C. & Lin, S. E., 十一月 2013, 於 : Clinical Lung Cancer. 14, 6, p. 719-725 7 p.研究成果: 雜誌貢獻 › 文章
13
引文
斯高帕斯（Scopus）
2012
Histone deacetylase inhibitor m-carboxycinnamic acid bis-hydroxamide attenuates plasminogen activator inhibitor-1 expression in human pleural mesothelial cells
Chung, C. L., Sheu, J. R., Chen, W. L., Chou, Y. C., Hsiao, C. J., Hsiao, S. H., Hsu, M. J., Cheng, Y. W. & Hsiao, G., 四月 2012, 於 : American Journal of Respiratory Cell and Molecular Biology. 46, 4, p. 437-445 9 p.研究成果: 雜誌貢獻 › 文章
8
引文
斯高帕斯（Scopus）
Pycnidione, a fungus-derived agent, induces cell cycle arrest and apoptosis in A549 human lung cancer cells
Hsiao, C. J., Hsiao, S. H., Chen, W. L., Guh, J. H., Hsiao, G., Chan, Y. J., Li, Z-H. & Chung, C. L., 四月 15 2012, 於 : Chemico-Biological Interactions. 197, 1, p. 23-30 8 p.研究成果: 雜誌貢獻 › 文章
21
引文
斯高帕斯（Scopus）
Suppression of matrix metalloproteinase-9 expression by andrographolide in human monocytic THP-1 cells via inhibition of NF-κB activation
Lee, W. R., Chung, C. L., Hsiao, C. J., Chou, Y. C., Hsueh, P. J., Yang, P. C., Jan, J. S., Cheng, Y. W. & Hsiao, G., 二月 15 2012, 於 : Phytomedicine. 19, 3-4, p. 270-277 8 p.研究成果: 雜誌貢獻 › 文章
22
引文
斯高帕斯（Scopus）
2011
Hypertonicity-enhanced TNF-α release from activated human monocytic THP-1 cells requires ERK activation
Chou, Y. C., Sheu, J. R., Chung, C. L., Hsiao, C. J., Hsueh, P. J. & Hsiao, G., 四月 2011, 於 : Biochimica et Biophysica Acta - General Subjects. 1810, 4, p. 475-484 10 p.研究成果: 雜誌貢獻 › 文章
7
引文
斯高帕斯（Scopus）
2010
Fluoroquinolone resistance of Pseudomonas aeruginosa isolates causing nosocomial infection is correlated with levofloxacin but not ciprofloxacin use
Lee, Y. J., Liu, H. Y., Lin, Y. C., Sun, K. L., Chun, C. L. & Hsueh, P. R., 三月 2010, 於 : International Journal of Antimicrobial Agents. 35, 3, p. 261-264 4 p.研究成果: 雜誌貢獻 › 文章
24
引文
斯高帕斯（Scopus）
Nuclear-targeted inhibition of NF-κB on MMP-9 production by N-2-(4-bromophenyl) ethyl caffeamide in human monocytic cells
Chou, Y. C., Sheu, J. R., Chung, C. L., Chen, C. Y., Lin, F. L., Hsu, M. J., Kuo, Y. H. & Hsiao, G., 三月 2010, 於 : Chemico-Biological Interactions. 184, 3, p. 403-412 10 p.研究成果: 雜誌貢獻 › 文章
51
引文
斯高帕斯（Scopus）
Pleural space elastance and changes in oxygenation after therapeutic thoracentesis in ventilated patients with heart failure and transudative pleural effusions
Chen, W. L., Chung, C. L., Hsiao, S. H. & Chang, S. C., 八月 2010, 於 : Respirology. 15, 6, p. 1001-1008 8 p.研究成果: 雜誌貢獻 › 文章
15
引文
斯高帕斯（Scopus）
Pseudo-Meigs' Syndrome Presenting as Lymphocytic Pleural Effusion with Elevated Adenosine Deaminase Activity-A Case Report
研究成果: 雜誌貢獻 › 文章
2009
Dynasore, a dynamin inhibitor, induces PAI-1 expression in MeT-5A human pleural mesothelial cells
Chung, C. L., Sheu, J. R., Liu, H. E., Chang, S. C., Chou, Y. C., Chen, W. L., Chou, D. S. & Hsiao, G., 六月 1 2009, 於 : American Journal of Respiratory Cell and Molecular Biology. 40, 6, p. 692-700 9 p.研究成果: 雜誌貢獻 › 文章
21
引文
斯高帕斯（Scopus）
Organizing Pneumonia Induced by Low-Dose, Short-Duration Amiodarone Therapy-A Case Report
研究成果: 雜誌貢獻 › 文章