癌症轉譯研究中心

研究成果 1958 2020

篩選
文章
2020

Intercalating pyrene with polypeptide as a novel self-assembly nano-carrier for colon cancer suppression in vitro and in vivo

Lo, P. Y., Lee, G. Y., Zheng, J. H., Huang, J. H., Cho, E. C. & Lee, K. C., 四月 1 2020, 於 : Materials Science and Engineering C. 109, 110593.

研究成果: 雜誌貢獻文章

Polypeptides
Pyrene
polypeptides
pyrenes
Self assembly

In vitro and in vivo evaluation of the neuroprotective activity of Uncaria hirsuta Haviland

Lin, C. M., Lin, Y. T., Lee, T. L., Imtiyaz, Z., Hou, W. C. & Lee, M. H., 一月 2020, 於 : Journal of Food and Drug Analysis. 28, 1, p. 147-158 12 p.

研究成果: 雜誌貢獻文章

開啟存取
Uncaria
neuroprotective effect
Inhibitory Concentration 50
inhibitory concentration 50
Oxidopamine

Melatonin activates cell death programs for the suppression of uterine leiomyoma cell proliferation

Lin, P. H., Tung, Y. T., Chen, H. Y., Chiang, Y. F., Hong, H. C., Huang, K. C., Hsu, S. P., Huang, T. C. & Hsia, S. M., 一月 1 2020, 於 : Journal of Pineal Research. 68, 1, e12620.

研究成果: 雜誌貢獻文章

Leiomyoma
Melatonin
Cell Death
Cell Proliferation
Myometrium
1 引文 (Scopus)

N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-γ induced PD-L1 expression

Mehndiratta, S., Lin, M. H., Wu, Y. W., Chen, C. H., Wu, T. Y., Chuang, K. H., Chao, M. W., Chen, Y. Y., Pan, S. L., Chen, M. C. & Liou, J. P., 一月 1 2020, 於 : European Journal of Medicinal Chemistry. 185, p. 111725 111725.

研究成果: 雜誌貢獻文章

Anilides
HSP90 Heat-Shock Proteins
Histone Deacetylase Inhibitors
Histone Deacetylases
Down-Regulation

NDAT suppresses pro-inflammatory gene expression to enhance resveratrol-induced anti-proliferation in oral cancer cells

Ho, Y., Wu, C. Y., Chin, Y. T., Li, Z. L., Pan, Y. S., Huang, T. Y., Su, P. Y., Lee, S. Y., Crawford, D. R., Su, K. W., Chiu, H. C., Shih, Y. J., Changou, C. A., Yang, Y. C. S. H., Whang-Peng, J., Chen, Y. R., Lin, H. Y., Mousa, S. A., Davis, P. J. & Wang, K., 二月 2020, 於 : Food and Chemical Toxicology. 136, 111092.

研究成果: 雜誌貢獻文章

Mouth Neoplasms
resveratrol
Gene expression
Cells
Gene Expression

Optimal measuring timing of cystatin C for early detection of contrast-induced acute kidney injury: A systematic review and meta-analysis

Chen, C. T., Chang, L. Y., Chuang, C. W., Wang, S. C., Kao, M. C., Tzeng, I. S., Kuo, K. L., Wu, C. C., Tsai, P. S. & Huang, C. J., 一月 2020, 於 : Toxicology Letters. 318, p. 65-73 9 p.

研究成果: 雜誌貢獻文章

Cystatin C
Acute Kidney Injury
Meta-Analysis
Contrast Media
Peripheral Catheterization

Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment

Kaur, N., Fang, Y. C., Lee, H. Y., Singh, A., Nepali, K., Lin, M. H., Yeh, T. K., Lai, M. J., Chan, L., Tu, Y. K., Banerjee, S., Hu, C. J. & Liou, J. P., 二月 1 2020, 於 : European Journal of Medicinal Chemistry. 187, 111915.

研究成果: 雜誌貢獻文章

Azepines
Histone Deacetylase Inhibitors
Blood Vessels
Acetylation
Acrylamide
2019
5 引文 (Scopus)
Benzamides
Histone Deacetylases
Tubulin
Heterografts
Inhibitory Concentration 50
Curcumin
Endothelin-1
Fibroblasts
Thrombin
Phosphotransferases

Adipose-derived Stem Cells Attenuates Diabetic Osteoarthritis via Inhibition of Glycation-mediated Inflammatory Cascade

Dubey, N. K., Wei, H-J., Yu, S. H., Williams, D. F., Wang, J. R., Deng, Y. H., Tsai, F. C., Wang, D. P. & Deng, W-P., 2019, 於 : Aging and Disease.

研究成果: 雜誌貢獻文章

Osteoarthritis
Stem Cells
Knee Joint
Advanced Glycosylation End Products
NF-kappa B
4 引文 (Scopus)

A double-virally-inactivated (Intercept–solvent/detergent) human platelet lysate for in vitro expansion of human mesenchymal stromal cells

Barro, L., Su, Y. T., Nebie, O., Wu, Y. W., Huang, Y. H., Koh, M. B. C., Knutson, F. & Burnouf, T., 一月 1 2019, 於 : Transfusion.

研究成果: 雜誌貢獻文章

Mesenchymal Stromal Cells
Detergents
Blood Platelets
Serum
In Vitro Techniques
3 引文 (Scopus)

A high linoleic acid diet exacerbates metabolic responses and gut microbiota dysbiosis in obese rats with diabetes mellitus

Lee, H. C., Yu, S. C., Lo, Y. C., Lin, I. H., Tung, T. H. & Huang, S. Y., 二月 1 2019, 於 : Food and Function. 10, 2, p. 786-798 13 p.

研究成果: 雜誌貢獻文章

Dysbiosis
Linoleic Acid
diabetes mellitus
intestinal microorganisms
linoleic acid
sex hormones
Gonadal Steroid Hormones
testosterone
Testosterone
Iron
1 引文 (Scopus)

Alteration of mesenchymal stem cells polarity by laminar shear stimulation promoting β-catenin nuclear localization

Chen, W-T., Hsu, W-T., Yen, M-H., Changou, C. A., Han, C-L., Chen, Y-J., Cheng, J-Y., Chang, T-H., Lee, O. K-S. & Ho, J. H-C., 一月 1 2019, 於 : Biomaterials. 190-191, p. 1-10 10 p.

研究成果: 雜誌貢獻文章

Catenins
Cell Polarity
Stem cells
Mesenchymal Stromal Cells
Shear stress
開啟存取
Air Pollution
Pleural Effusion
Pneumonia
Metals
Inflammation

An artificial intelligence approach to early predict non-ST-elevation myocardial infarction patients with chest pain

Wu, C. C., Hsu, W. D., Islam, M. M., Poly, T. N., Yang, H. C., Nguyen, P. AA., Wang, Y. C. & Li, Y. CJ., 五月 1 2019, 於 : Computer Methods and Programs in Biomedicine. 173, p. 109-117 9 p.

研究成果: 雜誌貢獻文章

Artificial Intelligence
Chest Pain
Artificial intelligence
Neural networks
Neural Networks (Computer)
3 引文 (Scopus)

Androgen deprivation-induced ZBTB46-PTGS1 signaling promotes neuroendocrine differentiation of prostate cancer

Chen, W. Y., Zeng, T., Wen, Y. C., Yeh, H. L., Jiang, K. C., Chen, W. H., Zhang, Q., Huang, J. & Liu, Y. N., 一月 1 2019, 於 : Cancer Letters. 440-441, p. 35-46 12 p.

研究成果: 雜誌貢獻文章

Prostaglandin-Endoperoxide Synthases
Androgens
Prostatic Neoplasms
Cyclooxygenase Inhibitors
Androgen Receptors
開啟存取
Triple Negative Breast Neoplasms
Histone Deacetylase Inhibitors
Radiation Tolerance
Autophagy
Proteins

Angiotensin-converting enzyme inhibitors or angiotensin receptor blocker monotherapy retard deterioration of renal function in Taiwanese chronic kidney disease population

Zheng, C. M., Wang, J. Y., Chen, T. T., Wu, Y. C., Wu, Y. L., Lin, H. T., Chiu, S. P., Chang, T. J., Zheng, J. Q., Chu, N. F., Lin, Y. M., Su, S. L., Lu, K. C., Chen, J. S., Sung, F. C., Lee, C. T., Yang, Y., Hwang, S. J., Wang, M. C., Hsu, Y. H. 及其他4, Chiou, H. Y., Kao, S., Wu, M. Y. & Lin, Y. F., 十二月 1 2019, 於 : Scientific Reports. 9, 1, 2694.

研究成果: 雜誌貢獻文章

開啟存取
Angiotensin Receptor Antagonists
Chronic Renal Insufficiency
Angiotensin-Converting Enzyme Inhibitors
Angiotensins
Kidney
2 引文 (Scopus)

An Open-Label, Multicenter, Phase I, Dose Escalation Study with Phase II Expansion Cohort to Determine the Safety, Pharmacokinetics, and Preliminary Antitumor Activity of Intravenous TKM-080301 in Subjects with Advanced Hepatocellular Carcinoma

El Dika, I., Lim, H. Y., Yong, W. P., Lin, C. C., Yoon, J. H., Modiano, M., Freilich, B., Choi, H. J., Chao, T. Y., Kelley, R. K., Brown, J., Knox, J., Ryoo, B. Y., Yau, T. & Abou-Alfa, G. K., 一月 1 2019, (接受/付印) 於 : Oncologist.

研究成果: 雜誌貢獻文章

開啟存取
Maximum Tolerated Dose
Hepatocellular Carcinoma
Pharmacokinetics
Safety
Small Interfering RNA
開啟存取
temozolomide
Glioblastoma
Phenotype
Glioma
Stem Cells
Single-Chain Antibodies
Epitopes
Escherichia coli
Amino Acids
OMPA outer membrane proteins
3 引文 (Scopus)

Anti-metastatic activity of MPT0G211, a novel HDAC6 inhibitor, in human breast cancer cells in vitro and in vivo

Hsieh, Y. L., Tu, H. J., Pan, S. L., Liou, J. P. & Yang, C. R., 六月 1 2019, 於 : Biochimica et Biophysica Acta - Molecular Cell Research. 1866, 6, p. 992-1003 12 p.

研究成果: 雜誌貢獻文章

Triple Negative Breast Neoplasms
Histone Deacetylase Inhibitors
Breast Neoplasms
Histone Deacetylases
Acetylation
2 引文 (Scopus)
Cholinergic Antagonists
Parkinson Disease
Dementia
Propensity Score
National Health Programs
Povidone-Iodine
Local Anti-Infective Agents
Chlorhexidine
Meta-Analysis
Randomized Controlled Trials
1 引文 (Scopus)

Antrocin, a bioactive component from Antrodia cinnamomea, suppresses breast carcinogenesis and stemness via downregulation of β-catenin/Notch1/Akt signaling

Chen, J. H., T.H Wu, A., T.W Tzeng, D., Huang, C. C., Tzeng, Y. M. & Chao, T. Y., 一月 1 2019, 於 : Phytomedicine. 52, p. 70-78 9 p.

研究成果: 雜誌貢獻文章

Antrodia
Catenins
Carcinogenesis
Breast
Down-Regulation

A probabilistic model for reducing medication errors: A sensitivity analysis using Electronic Health Records data

Huang, C. Y., Nguyen, P. A., Yang, H. C., Islam, M. M., Liang, C. W., Lee, F. P. & (Jack) Li, Y. C., 三月 1 2019, 於 : Computer Methods and Programs in Biomedicine. 170, p. 31-38 8 p.

研究成果: 雜誌貢獻文章

Medication Errors
Electronic Health Records
Statistical Models
Sensitivity analysis
Prescriptions
5 引文 (Scopus)

ASPM promotes prostate cancer stemness and progression by augmenting Wnt−Dvl-3−β-catenin signaling

Pai, V. C., Hsu, C. C., Chan, T. S., Liao, W. Y., Chuu, C. P., Chen, W-Y., Li, C. R., Lin, C. Y., Huang, S. P., Chen, L. T. & Tsai, K. K., 二月 21 2019, 於 : Oncogene. 38, 8, p. 1340-1353 14 p.

研究成果: 雜誌貢獻文章

Catenins
Microcephaly
Prostatic Neoplasms
Neoplastic Stem Cells
Neoplasms
開啟存取
Skin Neoplasms
ROC Curve
Medical Records
Learning
Trazodone
開啟存取
Acid Sensing Ion Channels
Brain Concussion
Dizziness
Alleles
Genes
1 引文 (Scopus)

Association between gout and cardiovascular disease risk: A nation-wide case-control study

Liang, C-W., Islam, M. M., Poly, T. N., Yang, H-C. & Jack Li, Y-C., 五月 2019, 於 : Joint Bone Spine.

研究成果: 雜誌貢獻文章

開啟存取
Atrial Fibrillation
Parkinson Disease
Population
Autonomic Nervous System
Case-Control Studies
1 引文 (Scopus)

Association between Use of Statin and Risk of Dementia: A Meta-Analysis of Observational Studies

Poly, T. N., Islam, M. M., Walther, B. A., Yang, H. C., Wu, C. C., Lin, M. C. & Li, Y. C., 一月 1 2019, (接受/付印) 於 : Neuroepidemiology.

研究成果: 雜誌貢獻文章

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Observational Studies
Dementia
Meta-Analysis
Odds Ratio
2 引文 (Scopus)

Association of chronic hepatitis B virus infection with age-related macular degeneration

Wu, C. M., Su, F. H., Wang, W. C., Lin, C. P., Kamiza, A. B., Chang, S. N. & Yeh, C. C., 一月 1 2019, 於 : Acta Ophthalmologica.

研究成果: 雜誌貢獻文章

Chronic Hepatitis B
Macular Degeneration
Virus Diseases
Hepatitis B virus
Cercopithecine Herpesvirus 1

Association of EGFR mutations and HMGB1 genetic polymorphisms in lung adenocarcinoma patients

Wu, Y. L., Chien, M. H., Chou, Y. E., Chang, J. H., Liu, T. C., Tsao, T. C. Y., Chou, M. C. & Yang, S. F., 一月 1 2019, 於 : Journal of Cancer. 10, 13, p. 2907-2914 8 p.

研究成果: 雜誌貢獻文章

開啟存取
HMGB1 Protein
Genetic Polymorphisms
Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Mutation

Association of endothelin genetic variants and hospitalized infection complications in end-stage renal disease (ESRD) patients

Kao, C. C., Cheng, S. Y., Wang, Y. J., Chien, S. C., Hsu, Y. W., Wu, M. Y., Lu, H. F., Nam, S., Sun, T., Wu, M. S. & Chang, W. C., 六月 5 2019, 於 : BMC Nephrology. 20, 1, p. 203 203.

研究成果: 雜誌貢獻文章

開啟存取
Endothelins
Chronic Kidney Failure
Bacteremia
Infection
Single Nucleotide Polymorphism
Taiwan
Nitric Oxide
Obesity
Psychology
Linear Models
2 引文 (Scopus)
開啟存取
Polysaccharides
Quality of Life
Neoplasms
Interleukin-13
Granulocyte-Macrophage Colony-Stimulating Factor
1 引文 (Scopus)
開啟存取
Astragalus
dendritic cells
lung neoplasms
Dendritic Cells
Polysaccharides
1 引文 (Scopus)
開啟存取
Penfluridol
Unfolded Protein Response
Lung Neoplasms
Cell Death
Adenosine Triphosphate

Bone mineral density as a dose-response predictor for osteoporosis: A propensity score analysis of longitudinal incident study (KCIS no. 39)

Yang, K. C., Wang, S. T., Lee, J. J., Fann, J. C. Y., Chiu, S. Y. H., Chen, S. L. S., Yen, A. M. F., Chen, H. H., Chen, M. K. & Hung, H. F., 五月 1 2019, 於 : QJM. 112, 5, p. 327-333 7 p.

研究成果: 雜誌貢獻文章

Propensity Score
Bone Density
Osteoporosis
Longitudinal Studies
Odds Ratio
4 引文 (Scopus)
bromelains
Bromelains
autophagy
Autophagy
colorectal neoplasms
Triple Negative Breast Neoplasms
Catenins
Neoplastic Stem Cells
Down-Regulation
Phenotype

Cellular Magnetic Resonance Imaging with Superparamagnetic Iron Oxide: Methods and Applications in Cancer

Hsu, F. T., Sun, R. & Hsieh, C. L., 一月 1 2019, 於 : SPIN.

研究成果: 雜誌貢獻文章

Iron oxides
iron oxides
magnetic resonance
cancer
Magnetic resonance

Characterization of T-Cell Receptor Repertoire in Patients with Rheumatoid Arthritis Receiving Biologic Therapies

Chang, C. M., Hsu, Y. W., Wong, H. S. C., Wei, J. C. C., Liu, X., Liao, H. T. & Chang, W. C., 一月 1 2019, 於 : Disease Markers. 2019, 1 p.

研究成果: 雜誌貢獻文章

開啟存取
Biological Therapy
Antirheumatic Agents
T-Cell Antigen Receptor
Antigen Receptors, T-Cell, alpha-beta
Rheumatoid Arthritis

Chemotherapy agents induce tartrate-resistant acid phosphatase 5a contributing to the symptom distress in lung cancer patients

Chou, H. L., Chao, T. Y., Chen, T. C., Chu, C. M., Hsieh, C. H., Lin, L. I. & Yao, C. T., 三月 5 2019, 於 : European Journal of Pharmacology. p. 38-48 11 p.

研究成果: 雜誌貢獻文章

Lung Neoplasms
Drug Therapy
Monocytes
Macrophages
gemcitabine
2 引文 (Scopus)
Pulmonary diseases
pneumonia
Air pollution
atmospheric pollution
confidence interval
1 引文 (Scopus)

Cluster of differentiation 14 and toll-like receptor 4 are involved in the anti-inflammatory effects of tyrosol

Chang, C. Y., Huang, I. T., Shih, H. J., Chang, Y. Y., Kao, M. C., Shih, P. C. & Huang, C. J., 二月 1 2019, 於 : Journal of Functional Foods. 53, p. 93-104 12 p.

研究成果: 雜誌貢獻文章

Toll-Like Receptor 4
anti-inflammatory activity
lipopolysaccharides
Lipopolysaccharides
Anti-Inflammatory Agents

Combined Effects of MMP-7, MMP-8 and MMP-26 on the Risk of Ischemic Stroke

Hsieh, F-I., Chiou, H-Y., Hu, C-J., Jeng, J-S., Lin, H-J., Lee, J-T. & Lien, L-M., 十一月 18 2019, 於 : Journal of Clinical Medicine. 8, 11

研究成果: 雜誌貢獻文章

Matrix Metalloproteinases
Stroke
Cardiovascular Diseases
Logistic Models
Causality

Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice

Chao, P. K., Chang, H. F., Ou, L. C., Chuang, J. Y., Lee, P. T., Chang, W. T., Chen, S. C., Ueng, S. H., Hsu, J. T. A., Tao, P. L., Law, P. Y., Loh, H. H. & Yeh, S. H., 十二月 1 2019, 於 : Scientific Reports. 9, 1, 2405.

研究成果: 雜誌貢獻文章

mu Opioid Receptor
Endocytosis
Morphine
Ligands
Morphine Dependence