每年專案
機構檔案
機構簡介
宗旨:
促進本校生技醫藥商品化發展,提供一校三院同仁醫藥品研發服務,以開發具有創新性與前瞻性之生技醫藥產品開發為宗旨。
背景:
生技醫藥為我國重要產業,建立藥品及醫材開發的關鍵價值鏈平台是校園研究成果產業化最大的助力。為有效統整及加速本校之新藥及醫材研發能量,規劃成立臺北醫學大學生技醫藥商品化中心(TMU Biomedical Commercialization Center),藉由商品化中心跨院系所專業團隊間的整合運作,提供一校三院同仁生技藥品臨床前到IND申請之臨床前研究(pre-clinical study)諮詢與服務。此外,透過北醫事業發展處協助醫藥品商品化開發策略,包含藥物市場定位分析,法規、專利檢索和諮詢服務,技術轉移或尋求業界承接產學合作案,及衍生新創事業體之相關規劃。
目的:
整合新藥開發及醫療器材從臨床前研究到IND/IDE所需之技術發展平台(Research Development),提供校內外單位委託合作或共同開發之服務。
搭配事業發展處之資源協助擬定生技醫藥品商業化發展策略(Business Development)、專利布局及商業化輔導,以加速產出具有創新性與前瞻性的生技醫藥品。
初期以藥品的商業化平台為目標:規劃由藥物設計/合成與篩選、藥理活性、藥物動力學、藥物代謝、藥效、毒理、小試量產、製劑開發等提供平台服務。
指紋
網路
概要
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張 偉嶠
- 臨床藥學學科 - 教授
- 應用分子流行病學碩士學位學程 - 合聘教授
- 臨床藥物基因體學暨蛋白質體學碩士學位學程 - 教授
- 新藥研發產業博士學位學程 - 合聘教授
- 癌症轉譯研究中心 - 成員
- 生技醫藥商品化中心
人員: Researcher
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陳 美全
- 藥物科學學科 - 副教授
- 中草藥臨床藥物研發博士學位學程 - 副教授
- 新藥研發產業博士學位學程 - 合聘副教授
- 生技醫藥商品化中心 - 成員
- 臺北醫學大學胸腔醫學研究中心 - 成員
人員: Researcher
專案
研究成果
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A novel histone deacetylase inhibitor MPT0L184 dysregulates cell-cycle checkpoints and initiates unscheduled mitotic signaling
Chang, T. Y., Nepali, K., Chen, Y. Y., Yang, Y. C. S. H., Hsu, K. C., Yen, Y., Pan, S. L., Liou, J. P. & Lee, S. B., 六月 2021, 於: Biomedicine and Pharmacotherapy. 138, 111485.研究成果: 雜誌貢獻 › 文章 › 同行評審
開啟存取 -
CAP rigidification of MS-275 and chidamide leads to enhanced antiproliferative effects mediated through HDAC1, 2 and tubulin polymerization inhibition
Singh, A., Chang, T. Y., Kaur, N., Hsu, K. C., Yen, Y., Lin, T. E., Lai, M. J., Lee, S. B. & Liou, J. P., 四月 5 2021, 於: European Journal of Medicinal Chemistry. 215, 113169.研究成果: 雜誌貢獻 › 文章 › 同行評審
2 引文 斯高帕斯(Scopus) -
Correlation between the expression of cancer stem cell marker BMI1 and glioma prognosis
Tsai, Y. T., Wu, C. C., Ko, C. Y., Hsu, T. I., Chang, W. C., Lo, W. L. & Chuang, J. Y., 四月 2021, 於: Biochemical and Biophysical Research Communications. 550, p. 113-119 7 p.研究成果: 雜誌貢獻 › 文章 › 同行評審
資料集
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MOESM4 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
Chien, C. (Contributor), Chuang, J. (Contributor), Yang, S. (Contributor), Yang, W. (Contributor), Chen, P. (Contributor), Hsu, T. (Contributor), Huang, C. (Contributor), Lo, W. (Contributor), Yang, K. (Contributor), Liu, M. (Contributor), Chu, J. (Contributor), Chung, P. (Contributor), Liu, J. (Contributor), Chou, S. (Contributor), Chen, S. (Contributor) & Chang, K. (Contributor), Unknown Publisher, 十月 19 2019
DOI: 10.6084/m9.figshare.10006862.v1, https://springernature.figshare.com/articles/MOESM4_of_Enrichment_of_superoxide_dismutase_2_in_glioblastoma_confers_to_acquisition_of_temozolomide_resistance_that_is_associated_with_tumor-initiating_cell_subsets/10006862/1
資料集: Dataset
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MOESM1 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
Chien, C. (Contributor), Chuang, J. (Contributor), Yang, S. (Contributor), Yang, W. (Contributor), Chen, P. (Contributor), Hsu, T. (Contributor), Huang, C. (Contributor), Lo, W. (Contributor), Yang, K. (Contributor), Liu, M. (Contributor), Chu, J. (Contributor), Chung, P. (Contributor), Liu, J. (Contributor), Chou, S. (Contributor), Chen, S. (Contributor) & Chang, K. (Contributor), Unknown Publisher, 一月 1 2019
DOI: 10.6084/m9.figshare.10006847.v1, https://springernature.figshare.com/articles/MOESM1_of_Enrichment_of_superoxide_dismutase_2_in_glioblastoma_confers_to_acquisition_of_temozolomide_resistance_that_is_associated_with_tumor-initiating_cell_subsets/10006847/1
資料集: Dataset
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MOESM6 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
Chien, C. (Contributor), Chuang, J. (Contributor), Yang, S. (Contributor), Yang, W. (Contributor), Chen, P. Y. (Contributor), Hsu, T. (Contributor), Huang, C. (Contributor), Lo, W. (Contributor), Yang, K. (Contributor), Liu, M. (Contributor), Chu, J. (Contributor), Chung, P. (Contributor), Liu, J. (Contributor), Chou, S. (Contributor), Chen, S. (Contributor) & Chang, K. (Contributor), Unknown Publisher, 一月 1 2019
DOI: 10.6084/m9.figshare.10006874.v1, https://springernature.figshare.com/articles/MOESM6_of_Enrichment_of_superoxide_dismutase_2_in_glioblastoma_confers_to_acquisition_of_temozolomide_resistance_that_is_associated_with_tumor-initiating_cell_subsets/10006874/1
資料集: Dataset