轉譯醫學博士學位學程

1998

Finding Medical Resources on the Internet

Li, Y. -C., 1998, 於: Yearbook of medical informatics. 1, p. 108-112 5 p.

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Inhibitory mechanisms of naloxone on human platelets

Sheu, J. R., Lee, Y. M., Lee, L. W., Luk, H. N. & Yen, M. H., 1998, 於: Clinical and Experimental Pharmacology and Physiology. 25, 7-8, p. 585-591 7 p.

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3 引文斯高帕斯（Scopus）

Ketoconazole-induced apoptosis through P53-dependent pathway in human colorectal and hepatocellular carcinoma cell lines

Ho, Y. S., Tsai, P. W., Yu, C. F., Liu, H. L., Chen, R. J. & Lin, J. K., 1998, 於: Toxicology and Applied Pharmacology. 153, 1, p. 39-47 9 p.

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36 引文斯高帕斯（Scopus）

Mechanisms involved in the antiplatelet activity of Escherichia coli lipopolysaccharide in human platelets

Sheu, J. R., Hung, W. C., Kan, Y. C., Lee, Y. M. & Yen, M. H., 1998, 於: British Journal of Haematology. 103, 1, p. 29-38 10 p.

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37 引文斯高帕斯（Scopus）

Mechanisms of cell death induced by nitric oxide and peroxynitrite in Calu-1 cells

Wang, Y. J., Ho, Y. S., Pan, M. H. & Lin, J. K., 八月 4 1998, 於: Environmental Toxicology and Pharmacology. 6, 1, p. 35-44 10 p.

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9 引文斯高帕斯（Scopus）

Pharmacological characteristics of MJ-451, a new benzopyran-derived ATP-sensitive potassium channel opener, in guinea pig isolated trachea

Lin, C-H., Lee, Y. M., Sheu, J. R., Cheng, C. Y., Chang, M. J. & Yen, M. H., 1998, 於: Pharmacology. 57, 6, p. 314-322 9 p.

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2 引文斯高帕斯（Scopus）

Regulation of integrin function: Evidence that bivalent-cation-induced conformational changes lead to the unmasking of ligand-binding sites within integrin α5β1

Mould, A. P., Garratt, A. N., Puzon-McLaughlin, W., Takada, Y. & Humphries, M. J., 五月 1 1998, 於: Biochemical Journal. 331, 3, p. 821-828 8 p.

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89 引文斯高帕斯（Scopus）

The ^-104G nucleotide of the human CYP21 gene is important for CYP21 transcription activity and protein interaction

Chin, K. K. & Chang, S. F., 四月 15 1998, 於: Nucleic Acids Research. 26, 8, p. 1959-1964 6 p.

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14 引文斯高帕斯（Scopus）

The antiplatelet activity of rutaecarpine, an alkaloid isolated from Evodia rutaecarpa, is mediated through inhibition of phospholipase C

Sheu, J. R., Kan, Y. C., Hung, W. C., Su, C-H., Lin, C. H., Lee, Y. M. & Yen, M. H., 十月 15 1998, 於: Thrombosis Research. 92, 2, p. 53-64 12 p.

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30 引文斯高帕斯（Scopus）

The negative influence of endogenous opioid receptor activity on the differentiation of the rat pheochromocytoma PC12 cells induced by nerve growth factor

Yeh, G. C., Hsieh, T. H. & Chang, S. F., 七月 27 1998, 於: Neuroscience Letters. 252, 1, p. 25-28 4 p.

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8 引文斯高帕斯（Scopus）

The selective antianginal effect without changing blood pressure of butylidenephthalide in conscious rats

Ko, W-C., Sheu, J. R., Tzeng, S-H. & Chen, C. M., 1998, 於: Planta Medica. 64, 3, p. 229-232 4 p.

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35 引文斯高帕斯（Scopus）

The suppression effect of DNA sequences within the C4A region on the transcription activity of human CYP21

Chang, S. F. & Cheng, C. L., 1998, 於: Endocrine Research. 24, 3-4, p. 625-630 6 p.

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2 引文斯高帕斯（Scopus）

1997

Changing ligand specificities of αvβ1 and αvβ3 integrins by swapping a short diverse sequence of the β subunit

Takagi, J., Kamata, T., Meredith, J., Puzon-McLaughlin, W. & Takada, Y., 八月 8 1997, 於: Journal of Biological Chemistry. 272, 32, p. 19794-19800 7 p.

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109 引文斯高帕斯（Scopus）

Comparing the Performance of Mathematical Models for Surgical Decisions on Head Injury Patients

Li, Y-C., Yang, T-F., Liu, L. & Chiu, W-T., 1997, 於: Journal of the American Medical Informatics Association : JAMIA. p. 870-

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Enhanced Na⁺-Ca²⁺ exchange activity in the regulation of vascular tone in spontaneously hypertensive rats

Lee, Y. M., Sheu, J. R. & Yen, M. H., 十二月 1997, 於: Asia Pacific Journal of Pharmacology. 12, 3-4, p. 71-76 6 p.

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Induction of glutathione depletion, p53 protein accumulation and cellular transformation by tetrachlorohydroquinone, a toxic metabolite of pentachlorophenol

Wang, Y. J., Ho, Y. S., Chu, S. W., Lien, H. J., Liu, T. H. & Lin, J. K., 六月 6 1997, 於: Chemico-Biological Interactions. 105, 1, p. 1-16 16 p.

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38 引文斯高帕斯（Scopus）

Inhibition of angiogenesis in vitro and in vivo: Comparison of the relative activities of triflavin, an Arg-Gly-Asp-containing peptide and anti-α(v)β₃ integrin monoclonal antibody

Sheu, J. R., Yen, M. H., Kan, Y. C., Hung, W. C., Chang, P. T. & Luk, H. N., 十月 20 1997, 於: Biochimica et Biophysica Acta - General Subjects. 1336, 3, p. 445-454 10 p.

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87 引文斯高帕斯（Scopus）

Interaction of thrombin-activated platelets with extracellular matrices (fibronectin and vitronectin): Comparison of the activity of Arg-Gly-Asp-containing venom peptides and monoclonal antibodies against glycoprotein IIb/IIIa complex

Sheu, J. R., Ko, W. C., Hung, W. C., Peng, H. C. & Huang, T. F., 一月 1997, 於: Journal of Pharmacy and Pharmacology. 49, 1, p. 78-84 7 p.

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9 引文斯高帕斯（Scopus）

Mechanisms involved in the antiplatelet activity of tetramethylpyrazine in human platelets

Sheu, J. R., Kan, Y. C., Hung, W. C., Ko, W. C. & Yen, M. H., 十一月 1 1997, 於: Thrombosis Research. 88, 3, p. 259-270 12 p.

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45 引文斯高帕斯（Scopus）

Multiple loop structures critical for ligand binding of the integrin α4 subunit in the upper face of the β-propeller mode

Irie, A., Kamata, T. & Takada, Y., 七月 8 1997, 於: Proceedings of the National Academy of Sciences of the United States of America. 94, 14, p. 7198-7203 6 p.

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60 引文斯高帕斯（Scopus）

Predialysis glycemic control is an independent predictor of clinical outcome in type II diabetics on continuous ambulatory peritoneal dialysis

Yu, C. C., Wu, M. S., Wu, C. H., Yang, C. W., Huang, J. Y., Hong, J. J., Chiang, C. Y. F., Leu, M. L. & Huang, C. C., 1997, 於: Peritoneal Dialysis International. 17, 3, p. 262-268 7 p.

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31 引文斯高帕斯（Scopus）

Role of nitric oxide in lipopolysaccharide-induced mortality from spontaneously hypertensive rats

Yen, M. H., Liu, Y. C., Hong, H. J., Sheu, J. R. & Wu, C. C., 三月 7 1997, 於: Life Sciences. 60, 15, p. 1223-1230 8 p.

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17 引文斯高帕斯（Scopus）

Stereoselectivity of butylidenephthalide on voltage-dependent calcium channels in guinea-pig isolated ileum

Ko, W-C., Sheu, J. R., Leu, Y. R., Tzeng, S-H. & Chen, C. M., 十一月 1997, 於: Journal of Pharmacy and Pharmacology. 49, 11, p. 1121-1125 5 p.

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15 引文斯高帕斯（Scopus）

Suppression of nitric oxide-induced apoptosis by N-acetyl-L-cysteine through modulation of glutathione, bcl-2, and bax protein levels

Ho, Y. S., Lee, H. M., Mou, T. C., Wang, Y. J. & Lin, J. K., 1997, 於: Molecular Carcinogenesis. 19, 2, p. 101-113 13 p.

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63 引文斯高帕斯（Scopus）

Traumatic brain injury registry in Taiwan

Chiu, W. T., Yeh, K. H., Li, Y. C., Can, Y. H., Chen, H. Y. & Hung, C. C., 1997, 於: Neurological Research. 19, 3, p. 261-264 4 p.

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40 引文斯高帕斯（Scopus）

Triflavin inhibits platelet-induced vasoconstriction in de- endothelialized aorta

Sheu, J. R., Yen, M. H., Hung, W. C., Lee, Y. M., Su, C-H. & Huang, T. F., 1997, 於: Arteriosclerosis, Thrombosis, and Vascular Biology. 17, 12, p. 3461-3468 8 p.

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22 引文斯高帕斯（Scopus）

建立臺灣醫療資訊交換中心之藍圖

Jian, W-S., Li, Y-C., 唐大鈿 & Hu, J-H., 1997, 於: 醫療資訊雜誌. 6, p. 54-66 13 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

網路內視鏡及超音波影像儲存與傳輸系統

Liu, L., Li, Y-C. & Pan, S., 1997, 於: 醫療資訊雜誌. 6, p. 1-10 10 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

網際網路在醫學上之應用

劉立 & 李友專, 1997, 於: 臺灣醫學. 1, 6, p. 727-732 6 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

醫學診斷決策支援系統

李友專, 劉立 & 邱文達, 1997, 於: 臺灣醫學. 1, 6, p. 722-726 5 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

1996

Activated conformations of very late activation integrins detected by a group of antibodies (HUTS) specific for a novel regulatory region (355-425) of the common β1 chain

Luque, A., Gómez, M., Puzon, W., Takada, Y., Sánchez-Madrid, F. & Cabañas, C., 1996, 於: Journal of Biological Chemistry. 271, 19, p. 11067-11075 9 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

256 引文斯高帕斯（Scopus）

Adenovirus interaction with distinct integrins mediates separate events in cell entry and gene delivery to hematopoietic cells

Huang, S., Kamata, T., Takada, Y., Ruggeri, Z. M. & Nemerow, G. R., 1996, 於: Journal of Virology. 70, 7, p. 4502-4508 7 p.

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開啟存取

211 引文斯高帕斯（Scopus）

Antihypertensive and hypolipidemic effects of DC-015, a novel, potent and specific α1-adrenoceptor antagonist: Comparison with prazosin in spontaneously hypertensive rats

Peng, I-H., Sheu, J-R., Chern, J-W., Lee, Y-M. & Yen, M-H., 1996, 於: Journal of Biomedical Science. 3, 2, p. 108-116 9 p.

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4 引文斯高帕斯（Scopus）

Critical residues for ligand binding in an I domain-like structure of the integrin β1 subunit

Puzon-McLaughlin, W. & Takada, Y., 1996, 於: Journal of Biological Chemistry. 271, 34, p. 20438-20443 6 p.

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79 引文斯高帕斯（Scopus）

Critical residues of integrin αIIb subunit for binding of αIIbβ3 (glycoprotein IIb-IIIa) to fibrinogen and ligand-mimetic antibodies (PAC-1, OP-G2, and LJ-CP3)

Kamata, T., Irie, A., Tokuhira, M. & Takada, Y., 1996, 於: Journal of Biological Chemistry. 271, 31, p. 18610-18615 6 p.

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79 引文斯高帕斯（Scopus）

Effects of DC-015, a novel potent and selective α1-adrenoceptor antagonist on plasma lipid and vascular reactivity in hyperlipidaemic rats

Sheu, J. R., Peng, I. H., Lee, Y. M. & Yen, M. H., 1996, 於: Clinical and Experimental Pharmacology and Physiology. 23, 3, p. 207-213 7 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

1 引文斯高帕斯（Scopus）

Induction of p53 and p21/WAF1/CIP1 expression by nitric oxide and their association with apoptosis in human cancer cells

Ho, Y. S., Wang, Y. J. & Lin, J. K., 五月 1996, 於: Molecular Carcinogenesis. 16, 1, p. 20-31 12 p.

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129 引文斯高帕斯（Scopus）

Mechanism of inhibition of platelet aggregation by rutaecarpine, an alkaloid isolated from Evodia rutaecarpa

Sheu, J. R., Hung, W. C., Lee, Y. M. & Yen, M. H., 十二月 30 1996, 於: European Journal of Pharmacology. 318, 2-3, p. 469-475 7 p.

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41 引文斯高帕斯（Scopus）

Peritoneal nitric oxide is a marker of peritonitis in patients on continuous ambulatory peritoneal dialysis

Yang, C. W., Hwang, T. L., Wu, C. H., Wu, M. S., Lai, P. C., Huang, J. Y., Yu, C. C., Shyr, M. H. & Huang, C. C., 十二月 1996, 於: Nephrology Dialysis Transplantation. 11, 12, p. 2466-2471 6 p.

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32 引文斯高帕斯（Scopus）

The common I172N mutation causes conformational change of cytochrome P450c21 revealed by systematic mutation, kinetic, and structural studies

Hsu, L. C., Hsu, N. C., Guzova, J. A., Guzov, V. M., Chang, S. F. & Chung, B. C., 二月 9 1996, 於: Journal of Biological Chemistry. 271, 6, p. 3306-3310 5 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

31 引文斯高帕斯（Scopus）

Triflavin, an Arg-Gly-Asp-Containing peptide, inhibits B16-F10 mouse melanoma cell adhesion to matrix proteins via direct binding to tumor cells

Sheu, J. R. & Huang, T. F., 1996, 於: Journal of Biomedical Science. 3, 5, p. 359-364 6 p.

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6 引文斯高帕斯（Scopus）

Triflavin, an arg-gly-asp-containing peptide, inhibits the adhesion of tumor cells to matrix proteins via binding to multiple integrin receptors expressed on human hepatoma cells

Sheu, J-R., Lin, C-H., Peng, H-C. & Huang, T-F., 十月 1996, 於: Proceedings of the Society for Experimental Biology and Medicine. 213, 1, p. 71-79 9 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

50 引文斯高帕斯（Scopus）

網際網路對醫療資訊傳播的影響

Li, Y-C., Liu, L. & 張慧朗, 1996, 於: 醫療資訊雜誌. 4, p. 78-87

研究成果: 雜誌貢獻 › 文章 › 同行評審

1995

Assessing the behavioral impact of a diagnostic decision support system.

Li, Y. C., Haug, P. J., Lincoln, M. J., Turner, C. W., Pryor, T. A. & Warner, H. H., 1995, 於: Proceedings / the ... Annual Symposium on Computer Application [sic] in Medical Care. Symposium on Computer Applications in Medical Care. p. 805-809 5 p.

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3 引文斯高帕斯（Scopus）

Cultured proximal cells derived from transgenic mouse provide a model to study drug toxicity

Riccaldi, D., Robic, D., Bens, M., Cluzeaud, F., Wu, M. S., Bourbouze, R. & Vandewalle, A., 九月 1995, 於: Kidney International. 48, 3, p. 722-730 9 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

12 引文斯高帕斯（Scopus）

Disintegrin modulates rat glomerular mesangial cell behavior

Tsai, T. J., Sheu, J. R., Chen, Y. M., Yen, C. J., Chen, C. F. & Huang, T. F., 1995, 於: Nephron. 70, 1, p. 83-90 8 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

13 引文斯高帕斯（Scopus）

Identification of putative ligand-binding sites of the integrin α4β1 (VLA-4, CD49d/CD29)

Kamata, T., Puzon, W. & Takada, Y., 1995, 於: Biochemical Journal. 305, 3, p. 945-951 7 p.

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121 引文斯高帕斯（Scopus）

Triflavin, an Arg-Gly-Asp-containing peptide, prevents platelet plug formation in in vivo experiments

Sheu, J. R., Yen, M. H., Peng, H. C., Chang, M. C. & Huang, T. F., 十二月 27 1995, 於: European Journal of Pharmacology. 294, 1, p. 231-238 8 p.

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22 引文斯高帕斯（Scopus）

1994

Hepatoprotective effects of Taiwan folk medicine: Alternanthera sessilis on liver damage induced by various hepatotoxins

Lin, S-C., Lin, Y., Shyuu, S. & Lin, C., 1994, 於: Phytotherapy Research. 8, 7, p. 391-398 8 p.

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25 引文斯高帕斯（Scopus）

N‐Nitroso‐2‐acetylaminofluorene: A Direct‐acting Carcinogen Inducing Hepatocellular Carcinoma in Sprague‐Dawley Rats

Ho, YS. S. & Lin, JK. K., 八月 1994, 於: Japanese Journal of Cancer Research. 85, 8, p. 794-800 7 p.

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4 引文斯高帕斯（Scopus）

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