轉譯醫學博士學位學程

2021

Aged skeletal muscle retains the ability to remodel extracellular matrix for degradation of collagen deposition after muscle injury

Chen, W. J., Lin, I. H., Lee, C. W. & Chen, Y. F., 二月 2 2021, 於: International journal of molecular sciences. 22, 4, p. 1-14 14 p., 2123.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

A novel method to retrieve alerts from a homegrown Computerized Physician Order Entry (CPOE) system of an academic medical center: Comprehensive alert characteristic analysis

Chien, S. C., Chin, Y. P. H., Yoon, C. H., Islam, M. M., Jian, W. S., Hsu, C. K., Chen, C. Y., Chien, P. H. & Li, Y. C. J., 二月 2021, 於: PLoS ONE. 16, 2 February, e0246597.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

Assessing the international transferability of a machine learning model for detecting medication error in the general internal medicine clinic: Multicenter preliminary validation study

Chin, Y. P. H., Song, W., Lien, C. E., Yoon, C. H., Wang, W. C., Liu, J., Nguyen, P. A., Feng, Y. T., Zhou, L., Li, Y. C. J. & Bates, D. W., 一月 2021, 於: JMIR Medical Informatics. 9, 1, e23454.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

Association of XRCC2 rs2040639 with the survival of patients with oral squamous cell carcinoma undergoing concurrent chemoradiotherapy

Senghore, T., Wang, W. C., Chien, H. T., Chen, Y. X., Young, C. K., Huang, S. F. & Yeh, C. C., 二月 2021, 於: Gene. 768, p. 145283 145283.

研究成果: 雜誌貢獻 › 文章 › 同行評審

Development of a web-based system for exploring cancer risk with long-term use of drugs: Logistic regression approach

Yang, H. C., Islam, M., Alex Nguyen, P. A., Wang, C. H., Poly, T. N., Huang, C. W. & Jack Li, Y. C., 二月 2021, 於: JMIR Public Health and Surveillance. 7, 2, p. e21401 e21401.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

1 引文斯高帕斯（Scopus）

Effect of chronic stress on expression and secretion of seminal vesicle proteins in adult rats

Iamsaard, S., Tongpan, S., Yannasithinon, S., Arun, S., Wu, A. T. H. & Sukhorum, W., 二月 2021, 於: Andrologia. 53, 1, e13800.

研究成果: 雜誌貢獻 › 文章 › 同行評審

1 引文斯高帕斯（Scopus）

Effects of Virtual Reality Sessions on the Quality of Life, Happiness, and Functional Fitness among the Older People: A Randomized Controlled Trial from Taiwan

Barsasella, D., Liu, M. F., Malwade, S., Galvin, C. J., Dhar, E., Chang, C. C., Li, Y. C. J. & Syed-Abdul, S., 三月 2021, 於: Computer Methods and Programs in Biomedicine. 200, 105892.

研究成果: 雜誌貢獻 › 文章 › 同行評審

ERK-mediated transcriptional activation of Dicer is involved in gemcitabine resistance of pancreatic cancer

Su, Y. H., Hsu, T. W., Chen, H. A., Su, C. M., Huang, M. T., Chuang, T. H., Leo Su, J., Hsieh, C. L. & Chiu, C. F., 六月 2021, 於: Journal of Cellular Physiology. 236, 6

研究成果: 雜誌貢獻 › 文章 › 同行評審

Genome-wide CRISPR/Cas9 knockout screening uncovers a novel inflammatory pathway critical for resistance to arginine-deprivation therapy

Chu, C. Y., Lee, Y. C., Hsieh, C. H., Yeh, C. T., Chao, T. Y., Chen, P. H., Lin, I. H., Hsieh, T. H., Shih, J. W., Cheng, C. H., Chang, C. C., Lin, P. S., Huang, Y. L., Chen, T. M., Yen, Y., Ann, D. K. & Kung, H. J., 2021, 於: Theranostics. 11, 8, p. 3624-3641 18 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

Hiltonol cocktail kills lung cancer cells by activating cancer-suppressors, pkr/oas and restraining the tumor microenvironment

Chang, S. C., Zhang, B. X., Su, E. C. Y., Wu, W. C., Hsieh, T. H., Salazar, A. M., Lin, Y. K. & Ding, J. L., 二月 2 2021, 於: International journal of molecular sciences. 22, 4, p. 1-23 23 p., 1626.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

Identification and characterization of L-amino acid oxidase 2 gene in orange-spotted grouper (Epinephelus coioides)

Leu, J. H., Tsai, C. H., Yang, C. H., Chou, H. Y. & Wang, H. C., 七月 2021, 於: Developmental and Comparative Immunology. 120, 104058.

研究成果: 雜誌貢獻 › 文章 › 同行評審

mTOR/EGFR/iNOS/MAP2K1/FGFR/TGFB1 Are Druggable Candidates for N-(2,4-Difluorophenyl)-2′,4′-Difluoro-4-Hydroxybiphenyl-3-Carboxamide (NSC765598), With Consequent Anticancer Implications

Lawal, B., Lee, C-Y., Mokgautsi, N., Sumitra, M. R., Khedkar, H., Wu, A. T. H. & Huang, H-S., 三月 2021, 於: Frontiers in Oncology. 11

研究成果: 雜誌貢獻 › 文章 › 同行評審

Multi‐omics data analysis of gene expressions and alterations, cancer‐associated fibroblast and immune infiltrations, reveals the onco‐immune prognostic relevance of stat3/cdk2/4/6 in human malignancies

Lawal, B., Lin, L. C., Lee, J. C., Chen, J. H., Bekaii‐saab, T. S., Wu, A. T. H. & Ho, C. L., 三月 1 2021, 於: Cancers. 13, 5, p. 1-26 26 p., 954.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

1 引文斯高帕斯（Scopus）

Structure-based strategies for synthesis, lead optimization and biological evaluation of N-substituted anthra[1,2-c][1,2,5]thiadiazole-6,11-dione derivatives as potential multi-target anticancer agents

Ali, A. A. A., Lee, Y. R., Wu, A. T. H., Yadav, V. K., Yu, D. S. & Huang, H. S., 二月 2021, 於: Arabian Journal of Chemistry. 14, 2, 102884.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

Synthesis and biological evaluation of phenothiazine derivative-containing hydroxamic acids as potent class II histone deacetylase inhibitors

Hsu, K-C., Chu, J-C., Tseng, H-J., Liu, C-I., Wang, H-C., Lin, T. E., Lee, H-S., Hsin, L-W., Wang, A. H-J., Lin, C-H. & Huang, W-J., 七月 2021, 於: European Journal of Medicinal Chemistry. 219

研究成果: 雜誌貢獻 › 文章 › 同行評審

2020

A Global Genome-wide Scan With Optimal Cutoff Mining for Emerging Biomarkers in Head and Neck Squamous Cell Carcinoma

Chi, L-H., Wu, A., Hsiao, M. & Li, Y-C., 十二月 4 2020, (未發布) 於: RESEARCH SQUARE.

研究成果: 雜誌貢獻 › 文章 › 同行評審

Alpha-1 blocker use increased risk of subsequent renal cell carcinoma: A nationwide population-based study in Taiwan

Sung, S. Y., Huynh Le, T. T., Chen, J. H., Hsieh, T. F. & Hsieh, C. L., 十一月 2020, 於: PLoS ONE. 15, 11 November, e0242429.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

A novel salicylanilide derivative induces autophagy cell death in castration-resistant prostate cancer via ER stress-activated PERK signaling pathway

Hsieh, C-L., Huang, H-S., Chen, K-C., Saka, T., Chiang, C-Y., Chung, L. W. K. & Sung, S-Y., 一月 1 2020, 於: Molecular Cancer Therapeutics. 19, 1, p. 101-111 11 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

3 引文斯高帕斯（Scopus）

Anti-tumor effect of hedgehog signaling inhibitor, vismodegib, on castration-resistant prostate cancer

Ishii, A., Shigemura, K., Kitagawa, K., Sung, S. Y., Chen, K. C., Yi-Te, C., Liu, M. C. & Fujisawa, M., 九月 1 2020, 於: Anticancer Research. 40, 9, p. 5107-5114 8 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

A Phase II Clinical Trial on the Combination Therapy of PHY906 Plus Capecitabine in Hepatocellular Carcinoma

Changou, C. A., Shiah, H. S., Chen, L. T., Liu, S., Luh, F., Liu, S. H., Cheng, Y. C. & Yen, Y., 2020, (接受/付印) 於: Oncologist. 26, 3, p. e367-e373

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

1 引文斯高帕斯（Scopus）

Application of a Common Data Model (CDM) to rank the paediatric user and prescription prevalence of 15 different drug classes in South Korea, Hong Kong, Taiwan, Japan and Australia: An observational, descriptive study

Brauer, R., Wong, I. C. K., Man, K. K. C., Pratt, N. L., Park, R. W., Cho, S. Y., Li, Y. C., Iqbal, U., Nguyen, P. A. A. & Schuemie, M., 一月 13 2020, 於: BMJ Open. 10, 1, p. e032426 032426.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

1 引文斯高帕斯（Scopus）

Artificial Intelligence in Ophthalmology: A Meta-Analysis of Deep Learning Models for Retinal Vessels Segmentation

Islam, M. M., Poly, T. N., Walther, B. A., Yang, H. C. & Li, Y-C. J., 四月 3 2020, 於: Journal of Clinical Medicine. 9, 4

研究成果: 雜誌貢獻 › 文章 › 同行評審

A shrimp glycosylase protein, PmENGase, interacts with WSSV envelope protein VP41B and is involved in WSSV pathogenesis

Huang, J. Y., Wang, H. C., Chen, Y. C., Wang, P. S., Lin, S. J., Chang, Y. S., Liu, K. F. & Lo, C. F., 七月 2020, 於: Developmental and Comparative Immunology. 108, 103667.

研究成果: 雜誌貢獻 › 文章 › 同行評審

Assessment of Predictive Scoring System for 90-Day Mortality Among Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma Who Have Completed Concurrent Chemoradiotherapy

Lin, K. C., Chen, T. M., Yuan, K. S. P., Wu, A. T. H. & Wu, S. Y., 三月 2 2020, 於: JAMA network open. 3, 3, p. e1920671

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

3 引文斯高帕斯（Scopus）

Association between benzodiazepines use and risk of hip fracture in the elderly people: A meta-analysis of observational studies

Poly, T. N., Islam, M. M., Yang, H. C. & Li, Y. C. J., 三月 2020, 於: Joint Bone Spine. 87, 3, p. 241-249

研究成果: 雜誌貢獻 › 文章 › 同行評審

1 引文斯高帕斯（Scopus）

Can ultrasound irradiation be a therapeutic option for prostate cancer?

Maeshige, N., Kitagawa, K., Yamasaki, S., Ishii, A., Shirakawa, T., Yang, Y. M., Sung, S. Y., Chen, K. C., Yuan, Z. M., Shigemura, K. & Fujisawa, M., 九月 1 2020, 於: Prostate. 80, 12, p. 986-992 7 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

Computational analysis for identification of the extracellular matrix molecules involved in endometrial cancer progression

Yadav, V. K., Lee, T. Y., Hsu, J. B. K., Huang, H. D., Yang, W. C. V. & Chang, T. H., 四月 1 2020, 於: PLoS ONE. 15, 4, p. e0231594 e0231594.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

1 引文斯高帕斯（Scopus）

Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability

Olie, C. S., van der Wal, E., Domagoj, C., Maton, L., de Greef, J. C., Lin, I. H., Chen, Y. F., Kareem, E., Penninger, J. M., Kessler, B. M. & Raz, V., 十二月 1 2020, 於: Scientific Reports. 10, 1, 17621.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

Erratum: Healthcare quality-improvement and measurement strategies and its challenges ahead

Iqbal, U., Humayun, A. & Li, Y. C. J., 十二月 15 2020, 於: International journal for quality in health care : journal of the International Society for Quality in Health Care. 32, 10, p. 722 1 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

Galectin-3 modulates macrophage activation and contributes smooth muscle cells apoptosis in abdominal aortic aneurysm pathogenesis

Lu, H. Y., Shih, C. M., Huang, C. Y., Wu, A. T. H., Cheng, T. M., Mi, F. L. & Shih, C. C., 十一月 1 2020, 於: International journal of molecular sciences. 21, 21, p. 1-15 15 p., 8257.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

Haptoglobin phenotype influences the effectiveness of diet-induced weight loss in middle-age abdominally obese women with metabolic abnormalities

Tang, K. Y., Huang, S. Y., Cheng, T. M., Bai, C. H. & Chang, J. S., 一月 2020, 於: Clinical Nutrition. 39, 1, p. 225-233 9 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

1 引文斯高帕斯（Scopus）

Localization (and profiles) of tyrosinephosphorylated proteins in female reproductive organs of adult rats

Bunsueb, S., Tangsrisakda, N., Wu, A. T. H. & Iamsaard, S., 九月 1 2020, 於: Clinical and Experimental Reproductive Medicine. 47, 3, p. 180-185 6 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

Macrophages protect mycoplasma-infected chronic myeloid leukemia cells from natural killer cell killing

Choo, Q. W. W., Koean, R. A. G., Chang, S. C., Chng, W. J., Chan, M. C., Wang, W., Er, J. Z. & Ding, J. L., 二月 1 2020, 於: Immunology and Cell Biology. 98, 2, p. 138-151 14 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

1 引文斯高帕斯（Scopus）

Microtube array membrane (MTAM)-based encapsulated cell therapy for cancer treatment

Chew, C. H., Lee, C. W., Huang, W. T., Cheng, L. W., Chen, A., Cheng, T. M., Liu, Y. L. & Chen, C. C., 四月 26 2020, 於: Membranes. 10, 5, 80.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

Modulating redox homeostasis and cellular reprogramming through inhibited methylenetetrahydrofolate dehydrogenase 2 enzymatic activities in lung cancer

Chan, C. H., Wu, C. Y., Dubey, N. K., Wei, H. J., Lu, J. H., Mao, S., Liang, J., Liang, Y. H., Cheng, H. C. & Deng, W. P., 九月 30 2020, 於: Aging. 12, 18, p. 17930-17947 18 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

1 引文斯高帕斯（Scopus）

NDAT Targets PI3K-Mediated PD-L1 Upregulation to Reduce Proliferation in Gefitinib-Resistant Colorectal Cancer

Huang, T. Y., Chang, T. C., Chin, Y. T., Pan, Y. S., Chang, W. J., Liu, F. C., Hastuti, E. D., Chiu, S. J., Wang, S. H., Changou, C. A., Li, Z. L., Chen, Y. R., Chu, H. R., Shih, Y. J., Cheng, R. H., Wu, A., Lin, H. Y., Wang, K., Whang-Peng, J., Mousa, S. A. 及其他1, Davis, P. J., 八月 3 2020, 於: Cells. 9, 8

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

3 引文斯高帕斯（Scopus）

Neoadjuvant metformin added to conventional chemotherapy synergizes anti-proliferative effects in ovarian cancer

Wen, K. C., Sung, P. L., Wu, A. T. H., Chou, P. C., Lin, J. H., Huang, C. Y. F., Yeung, S. C. J. & Lee, M. H., 八月 21 2020, 於: Journal of Ovarian Research. 13, 1, 95.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

Outcomes of adjuvant oral versus intravenous fluoropyrimidines for high-risk stage II or stage III colon adenocarcinoma: A propensity score-matched, nationwide, population-based cohort study

Zhang, J., Yen, Y. C., Qin, L., Chang, C. L., Yuan, K. S. P., Wu, A. T. H. & Wu, S. Y., 一月 1 2020, 於: Journal of Cancer. 11, 14, p. 4157-4165 9 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

Ovatodiolide, isolated from Anisomeles indica, suppresses bladder carcinogenesis through suppression of mTOR/β-catenin/CDK6 and exosomal miR-21 derived from M2 tumor-associated macrophages

Wu, A. T. H., Srivastava, P., Yadav, V. K., Tzeng, D. T. W., Iamsaard, S., Su, E. C. Y., Hsiao, M. & Liu, M. C., 八月 15 2020, 於: Toxicology and Applied Pharmacology. 401, p. 115109 115109.

研究成果: 雜誌貢獻 › 文章 › 同行評審

3 引文斯高帕斯（Scopus）

Ovatodiolide suppresses oral cancer malignancy by down-regulating exosomal mir-21/STAT3/β-catenin cargo and preventing oncogenic transformation of normal gingival fibroblasts

Chen, J. H., Wu, A. T. H., Bamodu, O. A., Yadav, V. K., Chao, T. Y., Tzeng, Y. M., Mukhopadhyay, D., Hsiao, M. & Lee, J. C., 一月 2020, 於: Cancers. 12, 1, 56.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

12 引文斯高帕斯（Scopus）

Overexpression of tyrosine phosphorylated proteins in reproductive tissues of polycystic ovary syndrome rats induced by letrozole

Bunsueb, S., Arun, S., Chaiyamoon, A., Wu, A. T. H. & Iamsaard, S., 十一月 1 2020, 於: Asian Pacific Journal of Reproduction. 9, 6, p. 275-282 8 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

1 引文斯高帕斯（Scopus）

Preclinical evaluation of the novel small-molecule msi-n1014 for treating drug-resistant colon cancer via the lgr5/β-catenin/mir-142-3p network and reducing cancer-associated fibroblast transformation

Yadav, V. K., Huang, Y. J., George, T. A., Wei, P. L., Sumitra, M. R., Ho, C. L., Chang, T. H., Wu, A. T. H. & Huang, H. S., 六月 16 2020, 於: Cancers. 12, 6, p. 1-15 15 p., 1590.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

1 引文斯高帕斯（Scopus）

Preclinical investigation of ovatodiolide as a potential inhibitor of colon cancer stem cells via downregulating sphere-derived exosomal β-catenin/STAT3/miR-1246 cargoes

Huang, Y-J., Huang, T. H., Yadav, V. K., Sumitra, M. R., Tzeng, D. T., Wei, P-L., Shih, J-W. & Wu, A. T., 2020, 於: American Journal of Cancer Research. 10, 8, p. 2337-2354 18 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

Predicting Lung Cancer Occurrence in Never-Smoking Females in Asia: TNSF-SQ, a Prediction Model

Chien, L. H., Chen, C. H., Chen, T. Y., Chang, G. C., Tsai, Y. H., Hsiao, C. F., Chen, K. Y., Su, W. C., Wang, W. C., Huang, M. S., Chen, Y. M., Chen, C. Y., Liang, S. K., Chen, C. Y., Wang, C. L., Lee, M. H., Chung, R. H., Tsai, F. Y., Hu, J. W., Katki, H. A. 及其他8, Chatterjee, N., Chanock, S. J., Rothman, N., Lan, Q., Yang, P. C., Chen, C. J., Chang, I. S. & Hsiung, C. A., 二月 1 2020, 於: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 29, 2, p. 452-459 8 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

3 引文斯高帕斯（Scopus）

Predictive value of genetic variants XRCC1 rs1799782, APEX1 rs1760944, and MUTYH rs3219489 for adjuvant concurrent chemoradiotherapy outcomes in oral squamous cell carcinoma patients

Senghore, T., Chien, H. T., Wang, W. C., Chen, Y. X., Young, C. K., Huang, S. F. & Yeh, C. C., 2020, (接受/付印) 於: Pharmacogenomics Journal. 20, 6, p. 813-822 10 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

Structural insight into the differential interactions between the DNA mimic protein SAUGI and two gamma herpesvirus uracil-DNA glycosylases

Liao, Y. T., Lin, S. J., Ko, T. P., Liu, C. Y., Hsu, K. C. & Wang, H. C., 十月 1 2020, 於: International Journal of Biological Macromolecules. 160, p. 903-914 12 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

Synthesis and characterization of magnetic nanoparticles coated with polystyrene sulfonic acid for biomedical applications

Chen, B. W., He, Y. C., Sung, S. Y., Le, T. T. H., Hsieh, C. L., Chen, J. Y., Wei, Z. H. & Yao, D. J., 一月 31 2020, 於: Science and Technology of Advanced Materials. 21, 1, p. 471-481 11 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取