轉譯醫學博士學位學程

  • No. 250 Wu-Xing Street

    11031 Taipei

研究成果 1995 2019

篩選
文章
2017
8 引文 (Scopus)

CISD2 Haploinsufficiency Disrupts Calcium Homeostasis, Causes Nonalcoholic Fatty Liver Disease, and Promotes Hepatocellular Carcinoma

Shen, Z. Q., Chen, Y. F., Chen, J. R., Jou, Y. S., Wu, P. C., Kao, C. H., Wang, C. H., Huang, Y. L., Chen, C. F., Huang, T. S., Shyu, Y. C., Tsai, S. F., Kao, L. S. & Tsai, T. F., 十一月 21 2017, 於 : Cell Reports. 21, 8, p. 2198-2211 14 p.

研究成果: 雜誌貢獻文章

Haploinsufficiency
Liver
Hepatocellular Carcinoma
Homeostasis
Calcium
3 引文 (Scopus)

Combinatorial treatment with polyI: C and anti-IL6 enhances apoptosis and suppresses metastasis of lung cancer cells

Lau, W. H., Zhu, X. G., Ho, S. W. T., Chang, S. C. & Ding, J-L., 2017, 於 : Oncotarget. 8, 20, p. 32884-32904 21 p.

研究成果: 雜誌貢獻文章

Interleukin-6
Lung Neoplasms
Apoptosis
Neoplasm Metastasis
Cytokines
17 引文 (Scopus)
Transcriptome
Epigenomics
Gene expression
epigenetics
Liver
2 引文 (Scopus)

CRP-level-associated polymorphism rs1205 within the CRP gene is associated with 2-hour glucose level: The SAPPHIRe study

Sheu, W. H. H., Wang, W. C., Wu, K. D., He, C. T., Hwu, C. M., Quertermous, T., Hsieh, W. S., Lee, W. J., Ting, C. T., Chen, Y. D. I. & Hsiung, C. A., 十二月 1 2017, 於 : Scientific Reports. 7, 1, p. 7987

研究成果: 雜誌貢獻文章

C-Reactive Protein
Insulin Resistance
Hypertension
Glucose
Genes

Cyproheptadine use in hepatocellular carcinoma

Hsieh, M. C., Lee, W. H., Wu, A. T. H., Chow, J. M., Chang, C. L., Yuan, K. S. P. & Wu, S. Y., 2017, 於 : American Journal of Cancer Research. 7, 3, p. 584-602 19 p.

研究成果: 雜誌貢獻文章

Cyproheptadine
Hepatocellular Carcinoma
Palliative Care
Cause of Death
Therapeutics
3 引文 (Scopus)

Direct binding to integrins and loss of disulfide linkage in IL-1β are involved in the agonistic action of IL-1β

Takada, Y. K., Yu, J., Fujita, M., Saegusa, J., Wu, C. Y. & Takada, Y., 一月 1 2017, 於 : Journal of Biological Chemistry. 292, 49, p. 20067-20075 9 p.

研究成果: 雜誌貢獻文章

Interleukin-1
Integrins
Disulfides
Interleukin-1 Receptors
Mutation
3 引文 (Scopus)

Direct integrin binding to insulin-like growth factor-2 through the C-domain is required for insulin-like growth factor receptor type 1 (IGF1R) signaling

Prieto, D. M. C., Cheng, Y., Chang, C. C., Yu, J., Takada, Y. K. & Takada, Y., 九月 1 2017, 於 : PLoS One. 12, 9, e0184285.

研究成果: 雜誌貢獻文章

IGF Type 1 Receptor
integrins
somatomedins
Somatomedins
Integrins
6 引文 (Scopus)

Distinct roles and differential expression levels of Wnt5a mRNA isoforms in colorectal cancer cells

Huang, T. C., Lee, P. T., Wu, M. H., Huang, C. C., Ko, C. Y., Lee, Y. C., Lin, D. Y., Cheng, Y. W. & Lee, K. H., 八月 1 2017, 於 : PLoS One. 12, 8, e0181034.

研究成果: 雜誌貢獻文章

RNA Isoforms
colorectal neoplasms
Colorectal Neoplasms
Catenins
Cells
3 引文 (Scopus)

Does aspirin use reduce the risk for cancer?

Usman, I., Yang, H. C., Jian, W. S., Yen, Y. & Li, Y. C., 二月 1 2017, 於 : Journal of Investigative Medicine. 65, 2, p. 391-392 2 p.

研究成果: 雜誌貢獻文章

Aspirin
Digestive system
Digestive System
Neoplasms
International Classification of Diseases
19 引文 (Scopus)
Intensity-Modulated Radiotherapy
Chemoradiotherapy
Thorax
Mortality
Neoplasms
17 引文 (Scopus)
Esophagectomy
Chemoradiotherapy
Radiotherapy
Thorax
Confidence Intervals
Epidermal Growth Factor Receptor
Squamous Cell Carcinoma
Lung Neoplasms
Adenocarcinoma
Radiotherapy
2 引文 (Scopus)

Endothelial angiogenesis is directed by RUNX1T1-regulated VEGFA, BMP4 and TGF-β2 expression

Liao, K. H., Chang, S. J., Chang, H. C., Chien, C. L., Huang, T. S., Feng, T. C., Lin, W. W., Shih, C. C., Yang, M. H., Yang, S. H., Lin, C. H., Hwang, W. L. & Lee, O. K., 六月 1 2017, 於 : PLoS One. 12, 6, e0179758.

研究成果: 雜誌貢獻文章

Endothelial cells
angiogenesis
Ischemia
Endothelial Cells
ischemia
14 引文 (Scopus)

Exploring association between statin use and breast cancer risk: an updated meta-analysis

Islam, M. M., Yang, H. C., Nguyen, P. A., Poly, T. N., Huang, C. W., Kekade, S., Khalfan, A. M., Debnath, T., Li, Y. C. J. & Abdul, S. S., 九月 22 2017, (接受/付印) 於 : Archives of Gynecology and Obstetrics. p. 1-11 11 p.

研究成果: 雜誌貢獻文章

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Meta-Analysis
Breast Neoplasms
Odds Ratio
Observational Studies
5 引文 (Scopus)

Exploring the Association between Statin Use and the Risk of Parkinson's Disease: A Meta-Analysis of Observational Studies

Poly, T. N., Islam, M. M., Walther, B. A., Yang, H. C., Nguyen, P. A., Huang, C. W., Shabbir, S. A. & Li, Y. C. J., 十二月 1 2017, 於 : Neuroepidemiology. 49, 3-4, p. 142-151 10 p.

研究成果: 雜誌貢獻文章

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Observational Studies
Parkinson Disease
Meta-Analysis
Simvastatin
7 引文 (Scopus)

Expression of a hepatitis B virus pre-S2 deletion mutant in the liver results in hepatomegaly and hepatocellular carcinoma in mice

Teng, Y. C., Neo, J. C., Wu, J. C., Chen, Y. F., Kao, C. H. & Tsai, T. F., 三月 1 2017, 於 : Journal of Pathology. 241, 4, p. 463-474 12 p.

研究成果: 雜誌貢獻文章

Hepatomegaly
Hepatitis B virus
Hepatocellular Carcinoma
Endoplasmic Reticulum
Liver
16 引文 (Scopus)

Feedback regulation of ALDOA activates the HIF-1α/MMP9 axis to promote lung cancer progression

Chang, Y. C., Chan, Y. C., Chang, W. M., Lin, Y. F., Yang, C. J., Su, C. Y., Huang, M. S., Wu, A. T. H. & Hsiao, M., 九月 10 2017, 於 : Cancer Letters. 403, p. 28-36 9 p.

研究成果: 雜誌貢獻文章

Hypoxia-Inducible Factor 1
Fructose-Bisphosphate Aldolase
Lung Neoplasms
Neoplasm Metastasis
Therapeutics
11 引文 (Scopus)
Neoplastic Stem Cells
Antioxidants
Side-Population Cells
Pancreatic Neoplasms
Tumors
2 引文 (Scopus)

Global Proteomics-based Identification and Validation of Thymosin Beta-4 X-Linked as a Prognostic Marker for Head and Neck Squamous Cell Carcinoma

Chi, L. H., Chang, W. M., Chang, Y. C., Chan, Y. C., Tai, C. C., Leung, K. W., Chen, C. L., Wu, A. T., Lai, T. C., Li, Y. C. & Hsiao, M., 十二月 1 2017, 於 : Scientific Reports. 7, 1, 9031.

研究成果: 雜誌貢獻文章

Proteomics
Biomarkers
Neoplasm Metastasis
Carcinoma, squamous cell of head and neck
thymosin beta(4)
10 引文 (Scopus)

Glucose transporter 4 promotes head and neck squamous cell carcinoma metastasis through the TRIM24-DDX58 axis

Chang, Y. C., Chi, L. H., Chang, W. M., Su, C. Y., Lin, Y. F., Chen, C. L., Chen, M. H., Chang, P. M. H., Wu, A. T. H. & Hsiao, M., 一月 7 2017, 於 : Journal of Hematology and Oncology. 10, 1, p. 1-12 12 p.

研究成果: 雜誌貢獻文章

Facilitative Glucose Transport Proteins
Neoplasm Metastasis
Glycolysis
Glucose
Carcinoma, squamous cell of head and neck
8 引文 (Scopus)
Neuropilin-1
Galectin 1
Hepatic Stellate Cells
Platelet-Derived Growth Factor
Transforming Growth Factors

Granulysin expressed in a humanized mouse model induces apoptotic cell death and suppresses tumorigenicity

Hsiao, Y. W., Lai, T. C., Lin, Y. H., Su, C. Y., Lee, J. J., Liao, A. T., Lin, Y. F., Hsieh, S. C., Wu, A. T. H. & Hsiao, M., 2017, 於 : Oncotarget. 8, 48, p. 83495-83508 14 p.

研究成果: 雜誌貢獻文章

Cell Death
Immune System
Cytotoxic T-Lymphocytes
Natural Killer Cells
Blood Cells
17 引文 (Scopus)
Macrophages
Selenium
Fluorescence
Nanoparticles
Imaging techniques
3 引文 (Scopus)

Inhibition of chronic prostate inflammation by hyaluronic acid through an immortalized human prostate stromal cell line model

Liu, C. M., Chen, W. H., Chiou, C. S., Lo, W. C., Dubey, N. K., Chen, Y. C., Lai, W. F. T., Yeh, S. D., Chiang, H. S. & Deng, W. P., 五月 1 2017, 於 : PLoS One. 12, 5, e0178152.

研究成果: 雜誌貢獻文章

hyaluronic acid
stromal cells
Hyaluronic Acid
Stromal Cells
Prostatic Hyperplasia
6 引文 (Scopus)
Cholangiocarcinoma
Case-Control Studies
Diabetes Mellitus
Population
Cholecystectomy
5 引文 (Scopus)

KLF10 loss in the pancreas provokes activation of SDF-1 and induces distant metastases of pancreatic ductal adenocarcinoma in the Kras(G12D) p53(flox/flox) model

Weng, C-C., Hawse, J. R., Subramaniam, M., Chang, V. H. S., Yu, W. C. Y., Hung, W-C., Chen, L-T. & Cheng, K-H., 九月 28 2017, 於 : Oncogene. 36, 39, p. 5532-5543 12 p.

研究成果: 雜誌貢獻文章

Pancreas
Adenocarcinoma
Transcription Factors
Neoplasm Metastasis
Neoplasms
3 引文 (Scopus)

Krüpple-like factor 10 regulates radio-sensitivity of pancreatic cancer via UV radiation resistance-associated gene

Chang, V. H. S., Tsai, Y. C., Tsai, Y. L., Peng, S. L., Chen, S. L., Chang, T. M., Yu, W. C. Y. & Ch'ang, H. J., 三月 1 2017, 於 : Radiotherapy and Oncology. 122, 3, p. 476-484

研究成果: 雜誌貢獻文章

Radio
Pancreatic Neoplasms
Radiation
Genes
Autophagy
24 引文 (Scopus)
Survival
Incidence
Recurrence
Comorbidity
Chemoradiotherapy
43 引文 (Scopus)

Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression

Shih, J. W., Chiang, W. F., Wu, A. T. H., Wu, M. H., Wang, L. Y., Yu, Y. L., Hung, Y. W., Wang, W. C., Chu, C. Y., Hung, C. L., Changou, C. A., Yen, Y. & Kung, H. J., 六月 22 2017, 於 : Nature Communications. 8, 15874.

研究成果: 雜誌貢獻文章

Long Noncoding RNA
Mouth Neoplasms
progressions
hypoxia
cancer
6 引文 (Scopus)

Lymphotoxin-β Interacts with Methylated EGFR to Mediate Acquired Resistance to Cetuximab in Head and Neck Cancer

Hsu, D. S-S., Hwang, W-L., Yuh, C-H., Chu, C-H., Ho, Y-H., Chen, P-B., Lin, H-S., Lin, H-K., Wu, S-P., Lin, C-Y., Hsu, W-H., Lan, H-Y., Wang, H-J., Tai, S-K., Hung, M-C. & Yang, M-H., 二月 14 2017, 於 : Clinical Cancer Research.

研究成果: 雜誌貢獻文章

Lymphotoxin-alpha
Head and Neck Neoplasms
Mutation
Protein-Arginine N-Methyltransferases
Genes
6 引文 (Scopus)
Magnetic Resonance Spectroscopy
Radiotherapy
Neoplasm Metastasis
Bone and Bones
Therapeutic Uses
4 引文 (Scopus)

Non-invasive in vivo molecular imaging of intra-articularly transplanted immortalized bone marrow stem cells for osteoarthritis treatment

Peng, B., Chiou, C-S., Dubey, N. K., Yu, S. H., Deng, Y. H., Tsai, F. C., Chiang, H. S., Shieh, Y-H., Chen, W. H. & Deng, W-P., 九月 27 2017, 於 : Oncotarget. 8, 57, p. 97153-97164

研究成果: 雜誌貢獻文章

Molecular Imaging
Luciferases
Bone Marrow Cells
Osteoarthritis
Stem Cells
17 引文 (Scopus)

Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways

Huang, Y. J., Yang, C. K., Wei, P. L., Huynh, T. T., Whang-Peng, J., Meng, T. C., Hsiao, M., Tzeng, Y. M., Wu, A. T. & Yen, Y., 二月 28 2017, 於 : Journal of hematology & oncology. 10, 1, p. 60 1 p.

研究成果: 雜誌貢獻文章

Colon
Carcinogenesis
Colonic Neoplasms
Macrophages
Neoplasms
4 引文 (Scopus)

Reactive oxygen species-mediated switching expression of MMP-3 in stromal fibroblasts and cancer cells during prostate cancer progression

Hsieh, C. L., Liu, C. M., Chen, H. A., Yang, S. T., Shigemura, K., Kitagawa, K., Yamamichi, F., Fujisawa, M., Liu, Y. R., Lee, W. H., Chen, K. C., Shen, C. N., Lin, C. C., Chung, L. W. K. & Sung, S. Y., 十二月 1 2017, 於 : Scientific Reports. 7, 1, 9065.

研究成果: 雜誌貢獻文章

Matrix Metalloproteinase 3
Reactive Oxygen Species
Prostatic Neoplasms
Fibroblasts
Neoplasms
12 引文 (Scopus)

REST is a crucial regulator for acquiring EMT-like and stemness phenotypes in hormone-refractory prostate cancer

Chang, Y. T., Lin, T. P., Campbell, M., Pan, C. C., Lee, S. H., Lee, H. C., Yang, M. H., Kung, H. J. & Chang, P. C., 三月 3 2017, 於 : Scientific Reports. 7, 42795.

研究成果: 雜誌貢獻文章

Epithelial-Mesenchymal Transition
Prostatic Neoplasms
Hormones
Phenotype
Castration
1 引文 (Scopus)

rs2841277 (PLD4) is associated with susceptibility and rs4672495 is associated with disease activity in rheumatoid arthritis

Chen, W. C., Wang, W. C., Lu, H. F., Okada, Y., Chang, W. P., Chou, Y. H., Chang, H. H., Huang, J. D., Chen, D. Y. & Chang, W. C., 2017, 於 : Oncotarget. 8, 38, p. 64180-64190 11 p.

研究成果: 雜誌貢獻文章

Phospholipase D
Rheumatoid Arthritis
Ankylosing Spondylitis
Single Nucleotide Polymorphism
Genome-Wide Association Study
7 引文 (Scopus)

The CD9, CD81, and CD151 EC2 domains bind to the classical RGD-binding site of integrin αvβ3

Yu, J., Lee, C. Y., Changou, C. A., Cedano-Prieto, D. M., Takada, Y. K. & Takada, Y., 二月 15 2017, 於 : Biochemical Journal. 474, 4, p. 589-596 8 p.

研究成果: 雜誌貢獻文章

Integrins
Binding Sites
Tetraspanins
Ligands
Cell adhesion
4 引文 (Scopus)

The concomitant association of thyroid disorders and Myasthenia gravis

Lin, P. Y., Iqbal, U., Nguyen, P. A., Islam, M. M., Atique, S., Jian, W. S., Li, Y. C., Huang, C. L. & Hsu, C. H., 一月 1 2017, 於 : Translational Neuroscience. 8, 1, p. 27-30 4 p.

研究成果: 雜誌貢獻文章

Myasthenia Gravis
Thyroid Gland
Poisons
Nodular Goiter
Thyrotoxicosis
4 引文 (Scopus)
Neoplastic Stem Cells
trichostatin A
Colonic Neoplasms
Colon
Carcinogenesis

The impact of different surgical procedures on hypoparathyroidism after thyroidectomy

Chen, K. C., Iqbal, U., Nguyen, P. A., Hsu, C. H., Huang, C. L., Hsu, Y. H. E., Atique, S., Islam, M. M., Li, Y. C. J. & Jian, W. S., 十月 1 2017, 於 : Medicine. 96, 43, p. e8245

研究成果: 雜誌貢獻文章

Hypoparathyroidism
Thyroidectomy
Thyroid Gland
National Health Programs
Lymph Node Excision
4 引文 (Scopus)

The integrin-binding defective FGF2 mutants potently suppress FGF2 signalling and angiogenesis

Mori, S., Hatori, N., Kawaguchi, N., Hamada, Y., Shih, T. C., Wu, C. Y., Lam, K. S., Matsuura, N., Yamamoto, H., Takada, Y. K. & Takada, Y., 四月 30 2017, 於 : Bioscience Reports. 37, 2, BSR20170173.

研究成果: 雜誌貢獻文章

Fibroblast Growth Factor 2
Integrins
Glutamic Acid
Biological Phenomena
Fibroblast Growth Factors
4 引文 (Scopus)

The monomeric form of Neisseria DNA mimic protein DMP19 prevents DNA from binding to the histone-like HU protein

Huang, M. F., Lin, S. J., Ko, T. P., Liao, Y. T., Hsu, K. C. & Wang, H. C., 十二月 1 2017, 於 : PLoS One. 12, 12, e0189461.

研究成果: 雜誌貢獻文章

Neisseria
histones
Histones
DNA
Dimers
3 引文 (Scopus)
Hemorrhoidectomy
Diltiazem
Ointments
Meta-Analysis
Randomized Controlled Trials

Two interrogated FBG spectral linewidth for strain sensing through correlation

Hsu, S. H., Chuang, K. W., Chen, C. S., Lin, C. Y. & Chang, C. C., 十二月 7 2017, 於 : Sensors (Switzerland). 17, 12, 2837.

研究成果: 雜誌貢獻文章

Elastic Tissue
Fiber Bragg gratings
Linewidth
Bragg gratings
fibers
8 引文 (Scopus)

Uncovering exposures responsible for birth season - disease effects: a global study

Boland, M. R., Parhi, P., Li, L., Miotto, R., Carroll, R., Iqbal, U., Nguyen, P-A. A., Schuemie, M., You, S. C., Smith, D., Mooney, S., Ryan, P., Li, Y-C. J., Park, R. W., Denny, J., Dudley, J. T., Hripcsak, G., Gentine, P. & Tatonetti, N. P., 九月 28 2017, 於 : Journal of the American Medical Informatics Association : JAMIA.

研究成果: 雜誌貢獻文章

Parturition
First Pregnancy Trimester
Republic of Korea
Electronic Health Records
Sunlight
12 引文 (Scopus)
Chemoradiotherapy
Thorax
Confidence Intervals
Therapeutics
Esophageal Squamous Cell Carcinoma
2018
3 引文 (Scopus)

Addressing stem cell therapeutic approaches in pathobiology of diabetes and its complications

Peng, B. Y., Dubey, N. K., Mishra, V. K., Tsai, F. C., Dubey, R., Deng, W. P. & Wei, H. J., 一月 1 2018, 於 : Journal of Diabetes Research. 2018, 7806435.

研究成果: 雜誌貢獻文章

Diabetes Complications
Diabetes Mellitus
Stem Cells
Multipotent Stem Cells
Pluripotent Stem Cells
7 引文 (Scopus)

Amentoflavone Induces Apoptosis and Inhibits NF-ĸB-modulated Anti-apoptotic Signaling in Glioblastoma Cells

Yen, T-H., Hsieh, C-L., Liu, T-T., Huang, C-S., Chen, Y-C., Chuang, Y-C., Lin, S-S. & Hsu, F-T., 二月 25 2018, 於 : In Vivo. 32, 2, p. 279-285 7 p.

研究成果: 雜誌貢獻文章

Glioblastoma
Apoptosis
Myeloid Leukemia
Myeloid Cells
Fas-Associated Death Domain Protein
4 引文 (Scopus)

Anti-TNF-α restricts dengue virus-induced neuropathy

Jhan, M. K., Huangfu, W. C., Chen, Y. F., Kao, J. C., Tsai, T. T., Ho, M. R., Shen, T. J., Tseng, P. C., Wang, Y. T. & Lin, C. F., 一月 1 2018, (接受/付印) 於 : Journal of Leukocyte Biology.

研究成果: 雜誌貢獻文章

Dengue Virus
Encephalitis
Virus Diseases
Dengue
Neurons