神經再生醫學博士學位學程

  • No. 250 Wu-Xing Street

    11031 Taipei

研究成果 2000 2019

2019
Siblings
Anisotropy
Communication
Phenotype
Diffusion Magnetic Resonance Imaging
開啟存取
Acid Sensing Ion Channels
Brain Concussion
Dizziness
Alleles
Genes

BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine

Chao, P. K., Chang, H. F., Chang, W. T., Yeh, T. K., Ou, L. C., Chuang, J. Y., Tsu-An Hsu, J., Tao, P. L., Loh, H. H., Shih, C., Ueng, S. H. & Yeh, S. H., 一月 1 2019, 於 : Neuropharmacology. 107678.

研究成果: 雜誌貢獻文章

Peptide Receptors
mu Opioid Receptor
Morphine
Naloxone
Arrestin

Cerebro-Cerebellar Pathways for Verbal Working Memory

Sobczak-Edmans, M., Lo, Y-C., Hsu, Y-C., Chen, Y-J., Kwok, F. Y., Chuang, K-H., Tseng, W-Y. I. & Chen, S. H. A., 2019, 於 : Frontiers in Human Neuroscience. 12, p. 530

研究成果: 雜誌貢獻文章

Short-Term Memory
Cerebellum
Parietal Lobe
Pons
Prefrontal Cortex

Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice

Chao, P. K., Chang, H. F., Ou, L. C., Chuang, J. Y., Lee, P. T., Chang, W. T., Chen, S. C., Ueng, S. H., Hsu, J. T. A., Tao, P. L., Law, P. Y., Loh, H. H. & Yeh, S. H., 十二月 1 2019, 於 : Scientific Reports. 9, 1, 2405.

研究成果: 雜誌貢獻文章

mu Opioid Receptor
Endocytosis
Morphine
Ligands
Morphine Dependence
temozolomide
Dehydroepiandrosterone
Glioblastoma
Acetylation
Phosphorylation
Neuronal Plasticity
Electric Impedance
Brain
Motor Evoked Potentials
Transcranial Magnetic Stimulation
Embryonal Carcinoma Stem Cells
Neural Stem Cells
Zinc Fingers
Transcription
Zinc

Editorial: Risk factors and outcome predicating biomarker of neurodegenerative diseases

Hu, C. J. & Octave, J. N., 一月 1 2019, 於 : Frontiers in Neurology. 10, February, 45.

研究成果: 雜誌貢獻回顧型文獻

開啟存取
Neurodegenerative Diseases
Parkinson Disease
Alzheimer Disease
Biomarkers
開啟存取
homing
brain damage
stem cells
fibroblasts
Fibroblasts

Gene-Embedded Nanostructural Biotic-Abiotic Optoelectrode Arrays Applied for Synchronous Brain Optogenetics and Neural Signal Recording

Huang, W. C., Chi, H. S., Lee, Y. C., Lo, Y. C., Liu, T. C., Chiang, M. Y., Chen, H. Y., Li, S. J., Chen, Y. Y. & Chen, S. Y., 三月 27 2019, 於 : ACS Applied Materials and Interfaces. 11, 12, p. 11270-11282 13 p.

研究成果: 雜誌貢獻文章

Brain
Genes
Polyethyleneimine
Neurotensin
Plasmids
開啟存取
Cell Cycle Proteins
Epithelial-Mesenchymal Transition
regulators
Prostatic Neoplasms
genes

Ketamine ameliorates severe traumatic event-induced antidepressant-resistant depression in a rat model through ERK activation

Lee, C. W., Chen, Y. J., Wu, H. F., Chung, Y. J., Lee, Y. C., Li, C. T. & Lin, H. C., 七月 13 2019, 於 : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 93, p. 102-113 12 p.

研究成果: 雜誌貢獻文章

Extracellular Signal-Regulated MAP Kinases
Ketamine
Antidepressive Agents
Serotonin Uptake Inhibitors
Depression
1 引文 (Scopus)

Leukemia Inhibitory Factor Promotes Castration-resistant Prostate Cancer and Neuroendocrine Differentiation by Activated ZBTB46

Liu, Y-N., Niu, S., Chen, W-Y., Zhang, Q., Tao, Y., Chen, W-H., Jiang, K-C., Chen, X., Shi, H., Liu, A., Li, J., Li, Y., Lee, Y-C., Zhang, X. & Huang, J., 四月 8 2019, 於 : Clinical cancer research : an official journal of the American Association for Cancer Research.

研究成果: 雜誌貢獻文章

Leukemia Inhibitory Factor
Castration
Prostatic Neoplasms
Androgens
Therapeutics

Morphological control of mitochondria as the novel mechanism of Gastrodia elata in attenuating mutant huntingtin-induced protein aggregations

Huang, N. K., Lin, C. C., Lin, Y. L., Huang, C. L., Chiou, C. T., Lee, Y. C., Lee, S. Y., Huang, H. T. & Yang, Y. C., 六月 1 2019, 於 : Phytomedicine. 59, 152756.

研究成果: 雜誌貢獻文章

Gastrodia
Mutant Proteins
Huntington Disease
Mitochondria
Mitochondrial Dynamics

MR imaging central thalamic deep brain stimulation restored autistic-like social deficits in the rat

Lin, T. C., Lo, Y. C., Lin, H. C., Li, S. J., Lin, S. H., Wu, H. F., Chu, M. C., Lee, C. W., Lin, I. C., Chang, C. W., Liu, Y. C., Chen, T. C., Lin, Y. J., Ian Shih, Y. Y. & Chen, Y. Y., 一月 1 2019, 於 : Brain Stimulation.

研究成果: 雜誌貢獻文章

Deep Brain Stimulation
Thalamic Nuclei
Magnetic Resonance Imaging
Interpersonal Relations
Brain
Coumarins
Cell death
Colonic Neoplasms
Cell Death
Cells

Pomalidomide Reduces Ischemic Brain Injury in Rodents

Tsai, Y. R., Tweedie, D., Navas-Enamorado, I., Scerba, M. T., Chang, C. F., Lai, J. H., Wu, J. C. C., Chen, Y. H., Kang, S. J., Hoffer, B. J., de Cabo, R., Greig, N. H., Chiang, Y. H. & Chen, K. Y., 四月 1 2019, 於 : Cell Transplantation. 28, 4, p. 439-450 12 p.

研究成果: 雜誌貢獻文章

開啟存取
Brain Injuries
Rodentia
Brain
Rats
Surface active agents

Potential therapeutic effect of curcumin, a natural mTOR inhibitor, in tuberous sclerosis complex

Kuo, C. J., Huang, C. C., Chou, S. Y., Lo, Y. C., Kao, T. J., Huang, N. K., Lin, C., Lin, H. C., Lin, H. C. & Lee, Y. C., 二月 15 2019, 於 : Phytomedicine. 54, p. 132-139 8 p.

研究成果: 雜誌貢獻文章

Tuberous Sclerosis
Curcumin
Therapeutic Uses
Memory Disorders
Lipids

Prevalence and clinical characteristics of stroke patients with p.R544C NOTCH3 mutation in Taiwan

Tang, S. C., Chen, Y. R., Chi, N. F., Chen, C. H., Cheng, Y. W., Hsieh, F. I., Hsieh, Y. C., Yeh, H. L., Sung, P. S., Hu, C. J., Chern, C. M., Lin, H. J., Lien, L. M., Peng, G. S., Chiou, H. Y. & Jeng, J. S., 一月 1 2019, 於 : Annals of Clinical and Translational Neurology. 6, 1, p. 121-128 8 p.

研究成果: 雜誌貢獻文章

Taiwan
Stroke
Mutation
Cerebral Hemorrhage
CADASIL

Promyelocytic leukemia zinc finger is involved in the formation of deep layer cortical neurons

Lin, H. C., Ching, Y. H., Huang, C. C., Pao, P. C., Lee, Y. H., Chang, W. C., Kao, T. J. & Lee, Y. C., 四月 26 2019, 於 : Journal of Biomedical Science. 26, 1, 30.

研究成果: 雜誌貢獻文章

開啟存取
Zinc Fingers
Neurons
Zinc
Leukemia
Brain
Brain Concussion
Psychometrics
Longitudinal Studies
Sleep
Anxiety

Sp1 in Astrocyte Is Important for Neurite Outgrowth and Synaptogenesis

Hung, C. Y., Hsu, T. I., Chuang, J. Y., Su, T. P., Chang, W. C. & Hung, J. J., 一月 1 2019, 於 : Molecular Neurobiology.

研究成果: 雜誌貢獻文章

Astrocytes
Synapses
Hippocampus
Neurons
Toll-Like Receptor 2

Unsupervised Classification of Cerebrospinal Fluid by Statistical Indicators

Lee, K. R., Yeh, Y. X., Wu, C. C., Lin, J. & Chiang, Y. H., 一月 16 2019, Proceedings - 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018. Institute of Electrical and Electronics Engineers Inc., p. 3827-3832 6 p. 8616645. (Proceedings - 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018).

研究成果: 書貢獻/報告類型會議貢獻

Cerebrospinal fluid
Cerebrospinal Fluid
Spinal Stenosis
Spinal Canal
Canals

Voluntary exercise delays progressive deterioration of markers of metabolism and behavior in a mouse model of Parkinson's disease

Lai, J. H., Chen, K. Y., Wu, J. C. C., Olson, L., Brené, S., Huang, C. Z., Chen, Y. H., Kang, S. J., Ma, K. H., Hoffer, B. J., Hsieh, T. H. & Chiang, Y. H., 十月 1 2019, 於 : Brain Research. 1720, 146301.

研究成果: 雜誌貢獻回顧型文獻

開啟存取
Parkinson Disease
Dopamine
Exercise
Dopamine Plasma Membrane Transport Proteins
Membrane Transport Proteins
2018
3 引文 (Scopus)
Activating Transcription Factors
CC Chemokines
Epithelial-Mesenchymal Transition
Androgens
Prostatic Neoplasms

A novel missense mutation of the GTP cyclohydrolase 1 gene in a Taiwanese family with dopa-responsive dystonia: A case report

Yang, C. C., Wang, W. C., Yeh, T. H., Chen, T. H., Liu, Y. L., Lu, M. K., Lu, C. S. & Tsai, C. H., 二月 1 2018, 於 : Clinical Neurology and Neurosurgery. 165, p. 21-23 3 p.

研究成果: 雜誌貢獻文章

GTP Cyclohydrolase
Missense Mutation
Dystonia
Genes
Leg
4 引文 (Scopus)

Astrocytic CCAAT/Enhancer-binding protein delta contributes to reactive oxygen species formation in neuroinflammation

Wang, S. M., Lim, S. W., Wang, Y. H., Lin, H. Y., Lai, M. D., Ko, C. Y. & Wang, J. M., 六月 1 2018, 於 : Redox Biology. 16, p. 104-112 9 p.

研究成果: 雜誌貢獻文章

CCAAT-Enhancer-Binding Protein-delta
Oxidative stress
Reactive Oxygen Species
Astrocytes
Oxidative Stress
2 引文 (Scopus)

C9orf72 is essential for neurodevelopment and motility mediated by Cyclin G1

Yeh, T. H., Liu, H. F., Li, Y. W., Lu, C. S., Shih, H. Y., Chiu, C. C., Lin, S. J., Huang, Y. C. & Cheng, Y. C., 六月 1 2018, 於 : Experimental Neurology. 304, p. 114-124 11 p.

研究成果: 雜誌貢獻文章

Cyclin G1
Embryonic Structures
GTP Phosphohydrolases
Zebrafish
Apoptosis
8 引文 (Scopus)

Caveolin-1 Controls Hyperresponsiveness to Mechanical Stimuli and Fibrogenesis-Associated RUNX2 Activation in Keloid Fibroblasts

Hsu, C. K., Lin, H. H., Harn, H. I., Ogawa, R., Wang, Y. K., Ho, Y. T., Chen, W. R., Lee, Y. C., Lee, J. Y. Y., Shieh, S. J., Cheng, C. M., McGrath, J. A. & Tang, M. J., 一月 1 2018, 於 : Journal of Investigative Dermatology. 138, 1, p. 208-218 11 p.

研究成果: 雜誌貢獻文章

Caveolin 1
Keloid
Fibroblasts
Chemical activation
trichostatin A
3 引文 (Scopus)
Stroke
Motor Cortex
Multivariate Analysis
Odds Ratio
Magnetic Resonance Imaging

Chronic pulmonary exposure to traffic-related fine particulate matter causes brain impairment in adult rats

Shih, C. H., Chen, J. K., Kuo, L. W., Cho, K. H., Hsiao, T. C., Lin, Z. W., Lin, Y. S., Kang, J. H., Lo, Y. C., Chuang, K. J., Cheng, T. J. & Chuang, H. C., 十一月 9 2018, 於 : Particle and Fibre Toxicology. 15, 1, 1 p.

研究成果: 雜誌貢獻文章

Particulate Matter
Rats
Brain
Hippocampus
Air Pollution
1 引文 (Scopus)
Epidermal Growth Factor Receptor
Protein-Tyrosine Kinases
Prostatic Neoplasms
Genes
Castration
6 引文 (Scopus)
Atrial Fibrillation
Safety
Hemorrhage
Myocardial Infarction
Rivaroxaban
1 引文 (Scopus)

Effect of traumatic brain injury on nicotine-induced modulation of dopamine release in the striatum and nucleus accumbens shell

Chen, Y. H., Kuo, T. T., Huang, E. Y. K., Chou, Y. C., Chiang, Y. H., Hoffer, B. J. & Miller, J., 一月 1 2018, 於 : Oncotarget. 9, 11, p. 10016-10028 13 p.

研究成果: 雜誌貢獻文章

Nucleus Accumbens
Nicotine
Dopamine
Percussion
Reward

Glucose-dependent insulinotropic polypeptide mitigates 6-OHDA-induced behavioral impairments in Parkinsonian rats

Yu, Y. W., Hsueh, S. C., Lai, J. H., Chen, Y. H., Kang, S. J., Chen, K. Y., Hsieh, T. H., Hoffer, B. J., Li, Y., Greig, N. H. & Chiang, Y. H., 四月 11 2018, 於 : International Journal of Molecular Sciences. 19, 4, 1153.

研究成果: 雜誌貢獻文章

Oxidopamine
Polypeptides
polypeptides
impairment
glucose
1 引文 (Scopus)
開啟存取
Oxidative Stress
Acetaminophen
Liver
Wounds and Injuries
Hep G2 Cells
1 引文 (Scopus)

Highly sensitive/selective 3D nanostructured immunoparticle-based interface on a multichannel sensor array for detecting amyloid-beta in Alzheimer's disease

Liu, T. C., Lee, Y. C., Ko, C. Y., Liu, R. S., Ke, C. C., Lo, Y. C., Hong, P. S., Chu, C. Y., Chang, C. W., Wu, P. W., Chen, Y. Y. & Chen, S. Y., 一月 1 2018, 於 : Theranostics. 8, 15, p. 4210-4225 16 p.

研究成果: 雜誌貢獻文章

Amyloid
Fibroins
Alzheimer Disease
Silk
Peptides
3 引文 (Scopus)
Human Umbilical Vein Endothelial Cells
Ischemia
Brain
Hypoxia
Genes
2 引文 (Scopus)

Individualized prediction of schizophrenia based on the whole-brain pattern of altered white matter tract integrity

Chen, Y. J., Liu, C. M., Hsu, Y. C., Lo, Y. C., Hwang, T. J., Hwu, H. G., Lin, Y. T. & Tseng, W. Y. I., 一月 1 2018, 於 : Human Brain Mapping. 39, 1, p. 575-587 13 p.

研究成果: 雜誌貢獻文章

Schizophrenia
Brain
Masks
ROC Curve
Biomarkers
1 引文 (Scopus)

LGK974, a PORCUPINE inhibitor, mitigates cytotoxicity in an in vitro model of Parkinson's disease by interfering with the WNT/β-CATENIN pathway

Yang, J. M., Huang, H. M., Cheng, J. J., Huang, C. L., Lee, Y. C., Chiou, C. T., Huang, H. T., Huang, N. K. & Yang, Y. C., 十二月 1 2018, 於 : Toxicology. 410, p. 65-72 8 p.

研究成果: 雜誌貢獻文章

Paraquat
Cytotoxicity
Parkinson Disease
Dopaminergic Neurons
Cell death
17 引文 (Scopus)

LRP10 genetic variants in familial Parkinson's disease and dementia with Lewy bodies: a genome-wide linkage and sequencing study

International Parkinsonism Genetics Network, 七月 1 2018, 於 : The Lancet Neurology. 17, 7, p. 597-608 12 p.

研究成果: 雜誌貢獻文章

Lewy Body Disease
Parkinson Disease
Genome
Dementia
Genes
5 引文 (Scopus)
Ubiquitination
Glioma
Glioblastoma
Stem Cells
temozolomide
5 引文 (Scopus)

Nano-diamino-tetrac (NDAT) inhibits PD-L1 expression which is essential for proliferation in oral cancer cells

Lin, S. J., Chin, Y. T., Ho, Y., Chou, S. Y., Sh Yang, Y. C., Nana, A. W., Su, K. W., Lim, Y. T., Wang, K., Lee, SY. Y., Shih, Y. J., Chen, Y. R., Whang-Peng, J., Davis, P. J., Lin, H. Y. & Fu, E., 十月 1 2018, 於 : Food and Chemical Toxicology. 120, p. 1-11 11 p.

研究成果: 雜誌貢獻文章

Mouth Neoplasms
Cells
death
Ligands
phosphatidylinositol 3-kinase

Nck2 is essential for limb trajectory selection by spinal motor axons

Chang, C. J., Chang, M. Y., Lee, Y. C., Chen, K. Y., Hsu, T. I., Wu, Y. H., Chuang, J. Y. & Kao, T. J., 九月 1 2018, 於 : Developmental Dynamics. 247, 9, p. 1043-1056 14 p.

研究成果: 雜誌貢獻文章

Axons
Extremities
Motor Neurons
Ephrins
Neurites

Neural Decoding Forelimb Trajectory Using Evolutionary Neural Networks with Feedback-Error-Learning Schemes

Lin, Y. C., Chou, C., Yang, S. H., Lai, H. Y., Lo, Y. C. & Chen, Y. Y., 十月 26 2018, 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018. Institute of Electrical and Electronics Engineers Inc., 卷 2018-July. p. 2539-2542 4 p. 8512775

研究成果: 書貢獻/報告類型會議貢獻

Brain-Computer Interfaces
Forelimb
Biomechanical Phenomena
Decoding
Trajectories

Nicotine-induced conditional place preference is affected by head injury: Correlation with dopamine release in the nucleus accumbens shell

Chen, Y. H., Kuo, T. T., Huang, E. Y. K., Hoffer, B. J., Kao, J. H., Chou, Y. C., Chiang, Y. H. & Miller, J., 十月 1 2018, 於 : International Journal of Neuropsychopharmacology. 21, 10, p. 949-961 13 p.

研究成果: 雜誌貢獻文章

Nucleus Accumbens
Nicotine
Craniocerebral Trauma
Dopamine
Percussion
2 引文 (Scopus)

PARK14 (D331Y) PLA2G6 Causes Early-Onset Degeneration of Substantia Nigra Dopaminergic Neurons by Inducing Mitochondrial Dysfunction, ER Stress, Mitophagy Impairment and Transcriptional Dysregulation in a Knockin Mouse Model

Chiu, C. C., Lu, C. S., Weng, Y. H., Chen, Y. L., Huang, Y. Z., Chen, R. S., Cheng, Y. C., Huang, Y. C., Liu, Y. C., Lai, S. C., Lin, K. J., Lin, Y. W., Chen, Y. J., Chen, C. L., Yeh, T. H. & Wang, H. L., 一月 1 2018, (接受/付印) 於 : Molecular Neurobiology.

研究成果: 雜誌貢獻文章

Mitochondrial Degradation
Dopaminergic Neurons
Substantia Nigra
Mutation
Parkinson Disease
2 引文 (Scopus)

Pomalidomide ameliorates H2O2-induced oxidative stress injury and cell death in rat primary cortical neuronal cultures by inducing anti-oxidative and anti-apoptosis effects

Tsai, Y. R., Chang, C. F., Lai, J. H., Wu, J. C. C., Chen, Y. H., Kang, S. J., Hoffer, B. J., Tweedie, D., Luo, W., Greig, N. H., Chiang, Y. H. & Chen, K. Y., 十月 19 2018, 於 : International Journal of Molecular Sciences. 19, 10

研究成果: 雜誌貢獻文章

Oxidative stress
apoptosis
Cell death
Cell culture
death