• No. 250 Wu-Xing Street

    11031 Taipei

研究成果 1985 2020

篩選
文章
2020

A cost-effectiveness analysis of trastuzumab-containing treatment sequences for HER-2 positive metastatic breast cancer patients in Taiwan

Diaby, V., Alqhtani, H., van Boemmel-Wegmann, S., Wang, C. Y., Ali, A. A., Balkrishnan, R., Ko, Y., Palacio, S. & de Lima Lopes, G., 二月 1 2020, 於 : Breast. 49, p. 141-148 8 p.

研究成果: 雜誌貢獻文章

開啟存取
docetaxel
Taiwan
Cost-Benefit Analysis
Breast Neoplasms
National Health Programs

An assessment of the psychometric properties of the Chinese version of the Gout Impact Scale

Pao, C. H. & Ko, Y., 一月 2 2020, 於 : Current Medical Research and Opinion. 36, 1, p. 17-21 5 p.

研究成果: 雜誌貢獻文章

Gout
Psychometrics
Aryl Hydrocarbon Receptors
Histone Deacetylase Inhibitors
Histone Deacetylases
Stomach Neoplasms
Cell Movement

Comparison of the predictive outcomes for anti-tuberculosis drug-induced hepatotoxicity by different machine learning techniques

Lai, N. H., Shen, W. C., Lee, C. N., Chang, J. C., Hsu, M. C., Kuo, L. N., Yu, M. C. & Chen, H. Y., 五月 2020, 於 : Computer Methods and Programs in Biomedicine. 188, 105307.

研究成果: 雜誌貢獻文章

Learning systems
Tuberculosis
Neural networks
ROC Curve
Support vector machines

Dramatically enhanced mechanical properties of diamond-like carbon films on polymer substrate for flexible display devices via argon plasma pretreatment

Lee, J. A., Lin, C. R., Pan, P. C., Liu, C. W. & Sun, A. Y. T., 一月 15 2020, 於 : Chemical Physics. 529, 110551.

研究成果: 雜誌貢獻文章

Flexible displays
Diamond like carbon films
Argon
argon plasma
display devices

Intercalating pyrene with polypeptide as a novel self-assembly nano-carrier for colon cancer suppression in vitro and in vivo

Lo, P. Y., Lee, G. Y., Zheng, J. H., Huang, J. H., Cho, E. C. & Lee, K. C., 四月 1 2020, 於 : Materials Science and Engineering C. 109, 110593.

研究成果: 雜誌貢獻文章

Polypeptides
Pyrene
polypeptides
pyrenes
Self assembly
1 引文 (Scopus)

N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-γ induced PD-L1 expression

Mehndiratta, S., Lin, M. H., Wu, Y. W., Chen, C. H., Wu, T. Y., Chuang, K. H., Chao, M. W., Chen, Y. Y., Pan, S. L., Chen, M. C. & Liou, J. P., 一月 1 2020, 於 : European Journal of Medicinal Chemistry. 185, p. 111725 111725.

研究成果: 雜誌貢獻文章

Anilides
HSP90 Heat-Shock Proteins
Histone Deacetylase Inhibitors
Histone Deacetylases
Down-Regulation

NDAT suppresses pro-inflammatory gene expression to enhance resveratrol-induced anti-proliferation in oral cancer cells

Ho, Y., Wu, C. Y., Chin, Y. T., Li, Z. L., Pan, Y. S., Huang, T. Y., Su, P. Y., Lee, S. Y., Crawford, D. R., Su, K. W., Chiu, H. C., Shih, Y. J., Changou, C. A., Yang, Y. C. S. H., Whang-Peng, J., Chen, Y. R., Lin, H. Y., Mousa, S. A., Davis, P. J. & Wang, K., 二月 2020, 於 : Food and Chemical Toxicology. 136, 111092.

研究成果: 雜誌貢獻文章

Nanofibers
Hydrogel
Hydrogels
Scaffolds
Suspensions

Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment

Kaur, N., Fang, Y. C., Lee, H. Y., Singh, A., Nepali, K., Lin, M. H., Yeh, T. K., Lai, M. J., Chan, L., Tu, Y. K., Banerjee, S., Hu, C. J. & Liou, J. P., 二月 1 2020, 於 : European Journal of Medicinal Chemistry. 187, 111915.

研究成果: 雜誌貢獻文章

Azepines
Histone Deacetylase Inhibitors
Blood Vessels
Acetylation
Acrylamide

Synthesis and biological evaluation of 2-quinolineacrylamides

Wang, S. W., Lin, M. H., Hsu, F. C., Chen, M. C., Liou, J. P., Liu, Y. T., Chen, S. S. & Lee, H. Y., 二月 1 2020, 於 : Bioorganic and Medicinal Chemistry. 28, 3, 115250.

研究成果: 雜誌貢獻文章

2019
5 引文 (Scopus)
Benzamides
Histone Deacetylases
Tubulin
Heterografts
Inhibitory Concentration 50
1 引文 (Scopus)

Alteration of mesenchymal stem cells polarity by laminar shear stimulation promoting β-catenin nuclear localization

Chen, W-T., Hsu, W-T., Yen, M-H., Changou, C. A., Han, C-L., Chen, Y-J., Cheng, J-Y., Chang, T-H., Lee, O. K-S. & Ho, J. H-C., 一月 1 2019, 於 : Biomaterials. 190-191, p. 1-10 10 p.

研究成果: 雜誌貢獻文章

Catenins
Cell Polarity
Stem cells
Mesenchymal Stromal Cells
Shear stress
Growth Inhibitors
Amides
Prostatic Neoplasms
Cells
Lead compounds
Social Welfare
Taiwan
Pharmacists
Pharmaceutical Services
Community Pharmacy Services

A novel preventive mechanism of gentamicin-induced nephrotoxicity by atorvastatin

Lee, M. C., Cheng, K. J., Chen, S. M., Li, Y. C., Imai, K., Lee, C. M. & Lee, J. A., 十一月 1 2019, 於 : Biomedical Chromatography. 33, 11, p. e4639 e4639.

研究成果: 雜誌貢獻文章

Gentamicins
Cathepsins
Metabolism
Proteomics
Macrophage Migration-Inhibitory Factors
3 引文 (Scopus)

Anti-metastatic activity of MPT0G211, a novel HDAC6 inhibitor, in human breast cancer cells in vitro and in vivo

Hsieh, Y. L., Tu, H. J., Pan, S. L., Liou, J. P. & Yang, C. R., 六月 1 2019, 於 : Biochimica et Biophysica Acta - Molecular Cell Research. 1866, 6, p. 992-1003 12 p.

研究成果: 雜誌貢獻文章

Triple Negative Breast Neoplasms
Histone Deacetylase Inhibitors
Breast Neoplasms
Histone Deacetylases
Acetylation
4 引文 (Scopus)

Applications of cyclic peptide nanotubes (cPNTs)

Hsieh, W. H. & Liaw, J., 一月 2019, (接受/付印) 於 : Journal of Food and Drug Analysis. 27, 1

研究成果: 雜誌貢獻文章

Peptide Nanotubes
nanotubes
cyclic peptides
Cyclic Peptides
drugs
2 引文 (Scopus)

Association between Anticholinergic Medication Use and Risk of Dementia among Patients with Parkinson's Disease

Sheu, J. J., Tsai, M. T., Erickson, S. R. & Wu, C. H., 一月 1 2019, 於 : Pharmacotherapy. 39, 8, p. 798-808 11 p.

研究成果: 雜誌貢獻文章

Cholinergic Antagonists
Parkinson Disease
Dementia
Taiwan
Confidence Intervals

Association of endothelin genetic variants and hospitalized infection complications in end-stage renal disease (ESRD) patients

Kao, C. C., Cheng, S. Y., Wang, Y. J., Chien, S. C., Hsu, Y. W., Wu, M. Y., Lu, H. F., Nam, S., Sun, T., Wu, M. S. & Chang, W. C., 六月 5 2019, 於 : BMC Nephrology. 20, 1, p. 203 203.

研究成果: 雜誌貢獻文章

開啟存取
Endothelins
Chronic Kidney Failure
Bacteremia
Infection
Single Nucleotide Polymorphism
Incentive Reimbursement
Metformin
Type 2 Diabetes Mellitus
Chronic Kidney Failure
Cohort Studies
4 引文 (Scopus)

Carboxylated carbon nanomaterials in cell cycle and apoptotic cell death regulation

Lee, K. C., Lo, P. Y., Lee, G. Y., Zheng, J. H. & Cho, E. C., 四月 20 2019, 於 : Journal of Biotechnology. 296, p. 14-21 8 p.

研究成果: 雜誌貢獻文章

Nanostructures
Cell death
Nanostructured materials
Cell Cycle
Cell Death

Characterization of T-Cell Receptor Repertoire in Patients with Rheumatoid Arthritis Receiving Biologic Therapies

Chang, C. M., Hsu, Y. W., Wong, H. S. C., Wei, J. C. C., Liu, X., Liao, H. T. & Chang, W. C., 一月 1 2019, 於 : Disease Markers. 2019, 1 p.

研究成果: 雜誌貢獻文章

開啟存取
Biological Therapy
Antirheumatic Agents
T-Cell Antigen Receptor
Antigen Receptors, T-Cell, alpha-beta
Rheumatoid Arthritis

Characterizing tyrosinase modulators from the roots of angelica keiskei using tyrosinase inhibition assay and UPLC-MS/MS as the combinatorial novel approach

Lee, J. H., Mei, H. C., Kuo, I. C., Lee, T. H., Chen, Y. H. & Lee, C. K., 九月 10 2019, 於 : Molecules. 24, 18, 3297.

研究成果: 雜誌貢獻文章

開啟存取
Angelica
Monophenol Monooxygenase
Modulators
modulators
Assays
3 引文 (Scopus)
Hypoxia-Inducible Factor 1
hypoxia
Autophagy
Chloramphenicol
Non-Small Cell Lung Carcinoma
1 引文 (Scopus)

Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status

Chao, M. W., Chang, L. H., Tu, H. J., Chang, C. D., Lai, M. J., Chen, Y. Y., Liou, J. P., Teng, C. M. & Pan, S. L., 五月 29 2019, 於 : Clinical Epigenetics. 11, 1, 85.

研究成果: 雜誌貢獻文章

開啟存取
Histone Deacetylase Inhibitors
Mitogen-Activated Protein Kinase Kinases
Pancreatic Neoplasms
Epidermal Growth Factor Receptor
Heterografts

Constructing a bilingual website with validated database for Herb and Western medicine interactions using Ginseng, Ginkgo and Dong Quai as examples

Wu, C. S., Chen, Y. H., Chen, C. L., Chien, S. K., Syifa, N., Hung, Y. C., Cheng, K. J., Hu, S. C., Lo, P. T., Lin, S. Y. & Wu, T. H., 十一月 27 2019, 於 : BMC Complementary and Alternative Medicine. 19, 1, 335.

研究成果: 雜誌貢獻文章

開啟存取
Herb-Drug Interactions
Ginkgo biloba
Panax
Medicine
Databases

Correction: Artocarpin, an isoprenyl flavonoid, induces p53-dependent or independent apoptosis via ROS-mediated MAPKs and akt activation in non-small cell lung cancer cells (Oncotarget (2017) 8 (28342–28358) DOI: 10.18632/oncotarget.16058)

Tsai, M. H., Liu, J. F., Chiang, Y. C., Hu, S. C. S., Hsu, L. F., Lin, Y. C., Lin, Z. C., Lee, H. C., Chen, M. C., Huang, C. L. & Lee, C. W., 五月 1 2019, 於 : Oncotarget. 10, 36, 1 p.

研究成果: 雜誌貢獻文章

開啟存取
Taiwan
Non-Small Cell Lung Carcinoma
Rehabilitation
Apoptosis
artocarpin flavonoid

Costs and Length of Stay of Hospitalizations due to Diabetes-Related Complications

Cheng, S. W., Wang, C. Y. & Ko, Y., 一月 1 2019, 於 : Journal of Diabetes Research. 2019, 2363292.

研究成果: 雜誌貢獻文章

開啟存取
Diabetes Complications
Length of Stay
Diabetes Mellitus
Hospitalization
Costs and Cost Analysis
2 引文 (Scopus)

Development of Decellularized Cornea by Organic Acid Treatment for Corneal Regeneration

Lin, H. J., Wang, T. J., Li, T. W., Chang, Y. Y., Sheu, M. T., Huang, Y. Y. & Liu, D. Z., 四月 1 2019, 於 : Tissue Engineering - Part A. 25, 7-8, p. 652-662 11 p.

研究成果: 雜誌貢獻文章

Organic acids
Scaffolds
Cornea
Regeneration
Swine
1 引文 (Scopus)

Divaricoside Exerts Antitumor Effects, in Part, by Modulating Mcl-1 in Human Oral Squamous Cell Carcinoma Cells

Weng, J. R., Bai, L. Y., Chiu, S. J., Chiu, C. F., Lin, W. Y., Hu, J. L. & Shieh, T. M., 一月 1 2019, 於 : Computational and Structural Biotechnology Journal. 17, p. 151-159 9 p.

研究成果: 雜誌貢獻文章

Glycosides
Squamous Cell Carcinoma
Cardiac Glycosides
Cells
Cell death

Does long-term use of antidiabetic drugs changes cancer risk?

Liu, Y. C., Nguyen, P. A., Humayun, A., Chien, S. C., Yang, H. C., Asdary, R. N., Syed-Abdul, S., Hsu, M. H., Moldovan, M., Yen, Y., Li, Y. C., Jian, W. S. & Iqbal, U., 十月 1 2019, 於 : Medicine (United States). 98, 40, p. e17461 e17461.

研究成果: 雜誌貢獻文章

開啟存取
Hypoglycemic Agents
pioglitazone
Neoplasms
Odds Ratio
Confidence Intervals

Down-regulation of aryl hydrocarbon receptor intensifies carcinogen-induced retinal lesion via SOCS3-STAT3 signaling

Tsai, C. H., Lee, Y., Li, C. H., Cheng, Y. W. & Kang, J. J., 一月 1 2019, (接受/付印) 於 : Cell Biology and Toxicology.

研究成果: 雜誌貢獻文章

Aryl Hydrocarbon Receptors
STAT3 Transcription Factor
Carcinogens
Down-Regulation
Cytokines
Biopolymers
Doxorubicin
Tumors
Colorectal Neoplasms
Cell Cycle

Efficacy of azatyrosine-phenylbutyric hydroxamides, a histone deacetylase inhibitor, on chemotherapy-induced gastrointestinal mucositis

Liao, P. L., Huang, S. H., Hung, C. H., Huang, W. K., Tsai, C. H., Kang, J. J., Wang, H. P. & Cheng, Y. W., 一月 1 2019, 於 : International Journal of Molecular Sciences. 20, 2, 249.

研究成果: 雜誌貢獻文章

monocytes
interleukins
Mucositis
Histone Deacetylase Inhibitors
Chemotherapy
1 引文 (Scopus)

Elucidation of the Effects of Si-Wu Tang on Menstrual Disorder Patterns through Activation of Aromatase and Antioxidation

Huang, G. C., Tsai, Y. Z., Lee, C. J., Chang, H. Y. & Wang, C. C., 三月 6 2019, 於 : Evidence-based Complementary and Alternative Medicine. 2019, p. 4761651 8 p., 4761651.

研究成果: 雜誌貢獻文章

開啟存取
Rehmannia
Aromatase
ferulic acid
Polyphenols
Estradiol
2 引文 (Scopus)

Expression of AHI1 Rescues Amyloidogenic Pathology in Alzheimer’s Disease Model Cells

Ting, L. L., Lu, H. T., Yen, S. F., Ngo, T. H., Tu, F. Y., Tsai, I. S., Tsai, Y. H., Chang, F. Y., Li, X. J., Li, S., Lee, C. K., Kao, S. H., Kuo, Y. M. & Lin, Y. F., 十一月 1 2019, 於 : Molecular Neurobiology. 56, 11, p. 7572-7582 11 p.

研究成果: 雜誌貢獻文章

Amyloid beta-Protein Precursor
Alzheimer Disease
Pathology
Amyloid
Protein C
1 引文 (Scopus)

Functional effects of let-7g expression in colon cancer metastasis

Chang, C. M., Wong, H. S. C., Huang, C. Y., Hsu, W. L., Maio, Z. F., Chiu, S. J., Tsai, Y. T., Chen, B. K., Wan, Y. J. Y., Wang, J. Y. & Chang, W. C., 四月 1 2019, 於 : Cancers. 11, 4, 489.

研究成果: 雜誌貢獻文章

開啟存取
Colonic Neoplasms
Colorectal Neoplasms
Neoplasm Metastasis
Neoplasms
Atlases

Gallate-induced nanoparticle uptake by tumor cells: Structure-activity relationships

Cheng, M. C., Lu, Y. C., Wu, J. & Ma, Y. H., 七月 1 2019, 於 : Colloids and Surfaces B: Biointerfaces. 179, p. 28-36 9 p.

研究成果: 雜誌貢獻文章

gallates
Structure-Activity Relationship
Nanoparticles
Tumors
tumors
2 引文 (Scopus)

Ganglioside Hp-s1 Analogue Inhibits Amyloidogenic Toxicity in Alzheimer's Disease Model Cells

Tsai, Y. F., Yang, D. J., Ngo, T. H., Shih, C. H., Wu, Y. F., Lee, C. K., Phraekanjanavichid, V., Yen, S. F., Kao, S. H., Lee, H. M., Huang, V. S., Shieh, J. C. C. & Lin, Y. F., 一月 16 2019, 於 : ACS Chemical Neuroscience. 10, 1, p. 528-536 9 p.

研究成果: 雜誌貢獻文章

Gangliosides
Amyloid beta-Protein Precursor
Toxicity
Alzheimer Disease
Cells

Genomic interrogation of familial short stature contributes to the discovery of the pathophysiological mechanisms and pharmaceutical drug repositioning

Wong, H. S. C., Lin, Y. J., Lu, H. F., Liao, W. L., Chen, C. H., Wu, J. Y., Chang, W. C. & Tsai, F. J., 十一月 7 2019, 於 : Journal of Biomedical Science. 26, 1, 91.

研究成果: 雜誌貢獻文章

開啟存取
Drug Repositioning
Genes
Pharmaceutical Preparations
Endocrine System
Genetic Loci
1 引文 (Scopus)

Glycemia Lowering Effect of an Aqueous Extract of Hedychium coronarium Leaves in Diabetic Rodent Models

Tse, L. S., Liao, P. L., Tsai, C. H., Li, C. H., Liao, J. W., Kang, J. J. & Cheng, Y. W., 三月 14 2019, 於 : Nutrients. 11, 3

研究成果: 雜誌貢獻文章

開啟存取
Hedychium coronarium
Zingiberaceae
Type 2 Diabetes Mellitus
blood glucose
Rodentia
1 引文 (Scopus)
Neuroglia
inhibitors
mice
Lipopolysaccharides
Chemical activation
1 引文 (Scopus)

High accuracy differentiating autoimmune pancreatitis from pancreatic ductal adenocarcinoma by immunoglobulin G glycosylation

Shih, H. C., Chang, M. C., Chen, C. H., Tsai, I. L., Wang, S. Y., Kuo, Y. P., Chen, C. H. & Chang, Y. T., 一月 3 2019, 於 : Clinical Proteomics. 16, 1

研究成果: 雜誌貢獻文章

開啟存取
Glycosylation
Pancreatitis
Adenocarcinoma
Immunoglobulin G
Regression Analysis

HSPB1 rs2070804 polymorphism is associated with the depth of primary tumor

Hung, C. S., Huang, C. Y., Hsu, Y. W., Makondi, P. T., Chang, W. C., Chang, Y. J., Wang, J. Y. & Wei, P. L., 一月 1 2019, 於 : Journal of Cellular Biochemistry.

研究成果: 雜誌貢獻文章

Polymorphism
Tumors
Colorectal Neoplasms
Single Nucleotide Polymorphism
Neoplasms
1 引文 (Scopus)

Hypersensitivity and cardiovascular risks related to allopurinol and febuxostat therapy in Asians: A population-based cohort study and meta-analysis

Chen, C-H., Chen, C-B., Chang, C. J., Lin, Y. J., Wang, C-W., Chi, C-C., Lu, C-W., Chen, W-T., Pan, R-Y., Su, S-C., Hsu, L-A., Chang, Y-C., Yu, K-H., Wu, Y-J. J., Lin, K-M., Hung, S-I., Chen, S-M. & Chung, W-H., 一月 28 2019, 於 : Clinical Pharmacology and Therapeutics.

研究成果: 雜誌貢獻文章

Allopurinol
Meta-Analysis
Hypersensitivity
Cohort Studies
Population

Impact of metformin use among tuberculosis close contacts with diabetes mellitus in a nationwide cohort study

Lee, M. C., Lee, C. H., Lee, M. R., Wang, J. Y. & Chen, S. M., 十一月 6 2019, 於 : BMC Infectious Diseases. 19, 1, 936.

研究成果: 雜誌貢獻文章

開啟存取
Metformin
Diabetes Mellitus
Tuberculosis
Cohort Studies
Insulin

Improved Dried Blood Spot-Based Metabolomics Analysis by a Postcolumn Infused-Internal Standard Assisted Liquid Chromatography-Electrospray Ionization Mass Spectrometry Method

Chepyala, D., Kuo, H. C., Su, K. Y., Liao, H. W., Wang, S. Y., Chepyala, S. R., Chang, L. C. & Kuo, C. H., 一月 1 2019, 於 : Analytical Chemistry.

研究成果: 雜誌貢獻文章

Electrospray ionization
Liquid chromatography
Mass spectrometry
Blood
Metabolites
Sleep
Cohort Studies
Brain Concussion
Brain Diseases
Traumatic Brain Injury

Induction of Apoptosis and Autophagy in Breast Cancer Cells by a Novel HDAC8 Inhibitor

Chiu, C. F., Chin, H. K., Huang, W. J., Bai, L. Y., Huang, H. Y. & Weng, J. R., 十二月 4 2019, 於 : Biomolecules. 9, 12

研究成果: 雜誌貢獻文章

開啟存取
Autophagy
Peroxisome Proliferator-Activated Receptors
MCF-7 Cells
Cells
Apoptosis