• No. 250 Wu-Xing Street

    11031 Taipei

研究成果 1985 2020

2014
16 引文 (Scopus)

A histone deacetylase inhibitor YCW1 with antitumor and antimetastasis properties enhances cisplatin activity against non-small cell lung cancer in preclinical studies

Huang, W. J., Tang, Y. A., Chen, M. Y., Wang, Y. J., Hu, F. H., Wang, T. W., Chao, S. W., Chiu, H. W., Yeh, Y. L., Chang, H. Y., Juan, H. F., Lin, P. & Wang, Y. C., 四月 28 2014, 於 : Cancer Letters. 346, 1, p. 84-93 10 p.

研究成果: 雜誌貢獻文章

Histone Deacetylase Inhibitors
Non-Small Cell Lung Carcinoma
Cisplatin
Lung Neoplasms
Neoplasms
25 引文 (Scopus)
Transforming Growth Factors
Angiotensin II
Androgens
Testosterone
Fibroblasts
14 引文 (Scopus)

An increase in reactive oxygen species by deregulation of ARNT enhances chemotherapeutic drug-induced cancer cell death

Shieh, J. M., Shen, C. J., Chang, W. C., Cheng, H. C., Chan, Y. Y., Huang, W. C., Chang, W. C. & Chen, B. K., 六月 12 2014, 於 : PLoS One. 9, 6, e99242.

研究成果: 雜誌貢獻文章

Aryl Hydrocarbon Receptor Nuclear Translocator
Deregulation
Cell death
hydrocarbons
cell death
7 引文 (Scopus)

A novel action mechanism for MPT0g013, a derivative of arylsulfonamide, inhibits tumor angiogenesis through upregulation of TIMP3 expression

Wang, C-Y., Liou, J. P., Tsai, A-C., Lai, M-J., Liu, Y-M., Lee, H. Y., Wang, J-C., Pan, S. L. & Teng, C-M., 2014, 於 : Oncotarget. 5, 20, p. 9838-9850 13 p.

研究成果: 雜誌貢獻文章

Tissue Inhibitor of Metalloproteinase-3
Up-Regulation
Neoplasms
Cell Cycle Resting Phase
Proteins
22 引文 (Scopus)
Histone Deacetylases
Cadherins
Protein Kinase C
Cell Differentiation
Colorectal Neoplasms
17 引文 (Scopus)
Histone Deacetylases
Human Activities
Refractory materials
Prostatic Neoplasms
Display devices
10 引文 (Scopus)

Anti-inflammatory effects of vitis thunbergii var. taiwaniana on knee damage associated with arthritis

Tsai, C. F., Wang, K. T., Chen, L. G., Lee, C. J., Tseng, S. H. & Wang, C. C., 四月 1 2014, 於 : Journal of Medicinal Food. 17, 4, p. 479-486 8 p.

研究成果: 雜誌貢獻文章

Vitis
Chondrocytes
Dietary Supplements
Dinoprostone
Arthritis
7 引文 (Scopus)

Antimitotic and vascular disrupting agents: 2-Hydroxy-3,4,5- trimethoxybenzophenones

Chang, C. Y., Chuang, H. Y., Lee, H. Y., Yeh, T. K., Kuo, C. C., Chang, C. Y., Chang, J. Y. & Liou, J. P., 四月 22 2014, 於 : European Journal of Medicinal Chemistry. 77, p. 306-314 9 p.

研究成果: 雜誌貢獻文章

Benzophenones
Antimitotic Agents
KB Cells
Endothelial cells
Human Umbilical Vein Endothelial Cells
42 引文 (Scopus)

Anti-proliferative and gene expression actions of resveratrol in breast cancer cells in vitro

Chin, Y. T., Hsieh, M. T., Yang, S. H., Tsai, P. W., Wang, S. H., Wang, C. C., Lee, Y. S., Cheng, G. Y., HuangFu, W. C., London, D., Tang, H. Y., Fu, E., Yen, Y., Liu, L. F., Lin, H. Y. & Davis, P. J., 2014, 於 : Oncotarget. 5, 24, p. 12891-12907 17 p.

研究成果: 雜誌貢獻文章

Breast Neoplasms
Gene Expression
Stilbenes
Cell Proliferation
Perfusion
11 引文 (Scopus)

A polymorphism of ORAI1 rs7135617, is associated with susceptibility to rheumatoid arthritis

Yen, J. H., Chang, C. M., Hsu, Y. W., Lee, C. H., Wu, M. S., Hwang, D. Y., Chen, B. K., Liao, H. T., Wu, M. T. M. & Chang, W. C., 2014, 於 : Mediators of Inflammation. 2014, 834831.

研究成果: 雜誌貢獻文章

Rheumatoid Arthritis
Genes
Single Nucleotide Polymorphism
Chronic Disease
Immune System Diseases
5 引文 (Scopus)

A relative bioavailability study of 500 mg calcium p-aminosalicylate film coating tablet in healthy individuals

Cheng, C., Chen, M. L., Tseng, C., Uang, Y. S., Huang, C. L. & Hsu, K. Y., 六月 1 2014, 於 : Journal of Food and Drug Analysis. 22, 2, p. 242-247 6 p.

研究成果: 雜誌貢獻文章

films (materials)
Biological Availability
Tablets
coatings
bioavailability
7 引文 (Scopus)

Association between Kawasaki disease and autism: A population-based study in Taiwan

Kuo, H. C., Wu, C. M., Chang, W. P., Kuo, C. N., Yeter, D., Lin, C. Y., Pai, J. T., Chi, Y. C., Lin, C. H., Wang, L. J. & Chang, W. C., 四月 3 2014, 於 : International Journal of Environmental Research and Public Health. 11, 4, p. 3705-3716 12 p.

研究成果: 雜誌貢獻文章

Mucocutaneous Lymph Node Syndrome
Autistic Disorder
Taiwan
Population
International Classification of Diseases
2 引文 (Scopus)

Association Between Statin Use and Bell’s Palsy: A Population-Based Study

Hung, S-H., Wang, L-H., Lin, H-C. & Chung, S. D., 2014, 於 : Drug Safety. 37, 9, p. 735-742 8 p.

研究成果: 雜誌貢獻文章

Bell Palsy
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Population
Health insurance
Health Insurance
33 引文 (Scopus)

Azaindolylsulfonamides, with a more selective inhibitory effect on histone deacetylase 6 activity, exhibit antitumor activity in colorectal cancer HCT116 cells

Lee, H. Y., Tsai, A. C., Chen, M. C., Shen, P. J., Cheng, Y. C., Kuo, C. C., Pan, S. L., Liu, Y. M., Liu, J. F., Yeh, T. K., Wang, J. C., Chang, C. Y., Chang, J. Y. & Liou, J. P., 五月 22 2014, 於 : Journal of Medicinal Chemistry. 57, 10, p. 4009-4022 14 p.

研究成果: 雜誌貢獻文章

HCT116 Cells
Histone Deacetylases
Colorectal Neoplasms
Histone Deacetylase Inhibitors
Heterografts
9 引文 (Scopus)
Chemical modification
Hyaluronic Acid
Oral Administration
Molecular Weight
Molecular weight
10 引文 (Scopus)

Carbamazepine attenuates inducible nitric oxide synthase expression through Akt inhibition in activated microglial cells

Wang, C. H., Hsiao, C. J., Lin, Y. N., Wu, J. W., Kuo, Y. C., Lee, C. K. & Hsiao, G., 十一月 1 2014, 於 : Pharmaceutical Biology. 52, 11, p. 1451-1459 9 p.

研究成果: 雜誌貢獻文章

Carbamazepine
Nitric Oxide Synthase Type II
Lipopolysaccharides
Cyclooxygenase 2
Reactive Oxygen Species
9 引文 (Scopus)

Carnosine ameliorates lens protein turbidity formations by inhibiting calpain proteolysis and ultraviolet C-induced degradation

Liao, J. H., Lin, I. L., Huang, K. F., Kuo, P. T., Wu, S. H. & Wu, T. H., 六月 25 2014, 於 : Journal of Agricultural and Food Chemistry. 62, 25, p. 5932-5938 7 p.

研究成果: 雜誌貢獻文章

Carnosine
Proteolysis
carnosine
Crystallins
calpain
10 引文 (Scopus)
drug delivery systems
Drug Delivery Systems
Polymer films
films (materials)
Plasticizers
3 引文 (Scopus)
Cross Infection
Taiwan
Acinetobacter baumannii
Acinetobacter Infections
Colistin
27 引文 (Scopus)

Comparison of chemical compositions and osteoprotective effects of different sections of velvet antler

Tseng, S. H., Sung, C. H., Chen, L. G., Lai, Y. J., Chang, W. S., Sung, H. C. & Wang, C. C., 一月 10 2014, 於 : Journal of Ethnopharmacology. 151, 1, p. 352-360 9 p.

研究成果: 雜誌貢獻文章

Antlers
Testosterone
Somatomedins
Osteocalcin
Femur
12 引文 (Scopus)
Triple Negative Breast Neoplasms
Cell Movement
Genes
Cells
Messenger RNA
1 引文 (Scopus)

Computer-aided discovery of potential inhibitors for transthyretin-related amyloidosis

Zhou, Z. L., Liu, H. L., Wu, J. W., Tsao, C. W., Chen, W. H., Liu, K. T. & Ho, Y., 2014, 於 : Journal of the Chinese Chemical Society. 61, 2, p. 263-273 11 p.

研究成果: 雜誌貢獻文章

Prealbumin
Screening
Amyloid
Molecular dynamics
Halogens
6 引文 (Scopus)

Concise syntheses of 7-anilino-indoline-N-benzenesulfonamides as antimitotic and vascular disrupting agents

Mehndiratta, S., Chiang, Y-F., Lai, M-J., Lee, H. Y., Chen, M. C., Kuo, C-C., Chang, C-Y., Chang, J-Y. & Liou, J. P., 九月 1 2014, 於 : Bioorganic and Medicinal Chemistry. 22, 17, p. 4917-4923 7 p.

研究成果: 雜誌貢獻文章

Antimitotic Agents
Blood Vessels
Cells
Cell Line
G2 Phase
10 引文 (Scopus)
Curcumin
Extracellular Matrix
Fibroblasts
Angiotensin II
Transforming Growth Factors
18 引文 (Scopus)

Deep sea water prevents balloon angioplasty-induced hyperplasia through MMP-2: An in vitro and in vivo study

Li, P. C., Pan, C. H., Sheu, M. J., Wu, C. C., Ma, W. F. & Wu, C. H., 五月 13 2014, 於 : PLoS One. 9, 5, e96927.

研究成果: 雜誌貢獻文章

gelatinase A
Balloon Angioplasty
Matrix Metalloproteinase 2
Balloons
Seawater
16 引文 (Scopus)

Denbinobin upregulates miR-146a expression and attenuates IL-1β-induced upregulation of ICAM-1 and VCAM-1 expressions in osteoarthritis fibroblast-like synoviocytes

Yang, C. R., Shih, K. S., Liou, J. P., Wu, Y. W., Hsieh, I. N., Lee, H. Y., Lin, T. C. & Wang, J. H., 十月 22 2014, 於 : Journal of Molecular Medicine. 92, 11, p. 1147-1158 12 p.

研究成果: 雜誌貢獻文章

Vascular Cell Adhesion Molecule-1
Intercellular Adhesion Molecule-1
MicroRNAs
Interleukin-1
Osteoarthritis
10 引文 (Scopus)

Detection of trace ink compounds in erased handwritings using electrospray-assisted laser desorption ionization mass spectrometry

Kao, Y. Y., Cheng, S. C., Cheng, C. N., Shiea, J. & Ho, H. O., 2014, 於 : Journal of Mass Spectrometry. 49, 6, p. 445-451 7 p.

研究成果: 雜誌貢獻文章

Handwriting
Ink
Ionization
Mass spectrometry
Desorption
8 引文 (Scopus)

Development and validation of an in vitroein vivo correlation (IVIVC) model for propranolol hydrochloride extended-release matrix formulations

Cheng, C., Wu, P. C., Lee, H. Y. & Hsu, K. Y., 六月 1 2014, 於 : Journal of Food and Drug Analysis. 22, 2, p. 257-263 7 p.

研究成果: 雜誌貢獻文章

propranolol
Propranolol
prediction
Validation Studies
Beagle
17 引文 (Scopus)

Direct formation of S-nitroso silica nanoparticles from a single silica source

Chou, H. C., Chiu, S. J., Liu, Y. L. & Hu, T. M., 一月 28 2014, 於 : Langmuir. 30, 3, p. 812-822 11 p.

研究成果: 雜誌貢獻文章

Nitric oxide
nitric oxide
Silicon Dioxide
Nitric Oxide
Silica
26 引文 (Scopus)

Dose effect of thiazolidinedione on cancer risk in type 2 diabetes mellitus patients: A six-year population-based cohort study

Lin, H. C., Hsu, Y. T., Kachingwe, B. H., Hsu, C-Y., Uang, Y. S. & Wang, L. H., 2014, 於 : Journal of Clinical Pharmacy and Therapeutics. 39, 4, p. 354-360 7 p.

研究成果: 雜誌貢獻文章

Thiazolidinediones
Type 2 Diabetes Mellitus
Cohort Studies
Population
Neoplasms
5 引文 (Scopus)

Dried fruit of the Luffa sponge as a source of chitin for applications as skin substitutes

Jiang, P. L., Chien, M. Y., Sheu, M. T., Huang, Y. Y., Chen, M. H., Su, C-H. & Liu, D. Z., 2014, 於 : BioMed Research International. 2014, 458287.

研究成果: 雜誌貢獻文章

Luffa
Artificial Skin
Chitin
Porifera
Fruits
5 引文 (Scopus)

Effect of C7-substitution of 1-arylsulfonyl-5-(N-hydroxyacrylamide)indolines on the selectivity towards a subclass of histone deacetylases

Lee, H. Y., Wang, L. T., Li, Y. H., Pan, S. L., Chen, Y. L., Teng, C. M. & Liou, J. P., 十一月 28 2014, 於 : Organic and Biomolecular Chemistry. 12, 44, p. 8966-8976 11 p.

研究成果: 雜誌貢獻文章

Histone Deacetylases
Tumors
Substitution reactions
selectivity
substitutes
19 引文 (Scopus)

Effects of metformin dose on cancer risk reduction in patients with type 2 diabetes mellitus: A 6-year follow-up study

Lin, H. C., Kachingwe, B. H., Lin, H. L., Cheng, H. W., Uang, Y. S. & Wang, L. H., 2014, 於 : Pharmacotherapy. 34, 1, p. 36-45 10 p.

研究成果: 雜誌貢獻文章

Metformin
Risk Reduction Behavior
Type 2 Diabetes Mellitus
Neoplasms
Hypoglycemic Agents
6 引文 (Scopus)
Nanodiamonds
Plasma jets
Diamond films
Film growth
Surface treatment
22 引文 (Scopus)
Dioscorea
yams
Galactose
galactose
tubers
7 引文 (Scopus)

Evaluating an online pharmaceutical education system for pharmacy interns in critical care settings

Yeh, Y. T., Chen, H. Y., Cheng, K. J., Hou, S. A., Yen, Y. H. & Liu, C. T., 二月 2014, 於 : Computer Methods and Programs in Biomedicine. 113, 2, p. 682-689 8 p.

研究成果: 雜誌貢獻文章

Pharmacy Education
Pharmacy Residencies
Critical Care
Drug products
Teaching
8 引文 (Scopus)

Evaluation of the antihyperuricemic activity of phytochemicals from Davallia formosana by enzyme assay and hyperuricemic mice model

Chen, C. Y., Huang, C. C., Tsai, K. C., Huang, W. J., Huang, W. C., Hsu, Y. C. & Hsu, F-L., 2014, 於 : Evidence-based Complementary and Alternative Medicine. 2014, 873607.

研究成果: 雜誌貢獻文章

Gout Suppressants
Xanthine Oxidase
Enzyme Assays
Phytochemicals
Uric Acid
1 引文 (Scopus)

Facile method for determination of deoxycytidine kinase activity in biological milieus

Hao, W. H., Yang, L. C., Wang, J. J., Hsu, C. S., Chang, L. C. & Hsu, K. Y., 六月 1 2014, 於 : Journal of Food and Drug Analysis. 22, 2, p. 236-241 6 p.

研究成果: 雜誌貢獻文章

Deoxycytidine Kinase
bioactive properties
phosphotransferases (kinases)
adenosine triphosphate
gemcitabine
18 引文 (Scopus)

Female gender and acne disease are jointly and independently associated with the risk of major depression and suicide: A national population-based study

Yang, Y. C., Tu, H. P., Hong, C. H., Chang, W. C., Fu, H. C., Ho, J. C., Chang, W. P., Chuang, H. Y. & Lee, C. H., 2014, 於 : BioMed Research International. 2014, 504279.

研究成果: 雜誌貢獻文章

Acne Vulgaris
Suicide
Depression
Population
Health insurance
3 引文 (Scopus)

Genetic polymorphisms of ORAI1 and chronic kidney disease in Taiwanese population

Hwang, D. Y., Chien, S-C., Hsu, Y. W., Kao, C. C., Cheng, S. Y., Lu, H. C., Wu, M. S. & Chang, J. M., 2014, 於 : BioMed Research International. 2014, 290863.

研究成果: 雜誌貢獻文章

Genetic Polymorphisms
Polymorphism
Chronic Renal Insufficiency
Population
HapMap Project
6 引文 (Scopus)

Genetic variants of CD209 associated with Kawasaki disease susceptibility

Kuo, H. C., Huang, Y. H., Chien, S-C., Yu, H. R., Hsieh, K. S., Hsu, Y. W. & Chang, W. C., 八月 22 2014, 於 : PLoS One. 9, 8, e105236.

研究成果: 雜誌貢獻文章

Mucocutaneous Lymph Node Syndrome
Disease Susceptibility
disease resistance
haplotypes
coronary vessels
19 引文 (Scopus)

Higher expression of whole blood microRNA-21 in patients with ankylosing spondylitis associated with programmed cell death 4 mRNA expression and collagen cross-linked C-telopeptide concentration

Huang, C. H., Wei, J. C. C., Chang, W. C., Chiou, S. Y., Chou, C. H., Lin, Y. J., Hung, P. H. & Wong, R. H., 2014, 於 : Journal of Rheumatology. 41, 6, p. 1104-1111 8 p.

研究成果: 雜誌貢獻文章

Ankylosing Spondylitis
MicroRNAs
Cell Death
Collagen
Messenger RNA
10 引文 (Scopus)

Hypoxia inducible factor 2α/insulin-like growth factor receptor signal loop supports the proliferation and Oct-4 maintenance of mouse germline stem cells

Huang, Y-H., Lin, M-H., Wang, P. C., Wu, Y. C., Chiang, H. L., Wang, Y. L., Chang, J. H., Huang, Y. K., Gu, S. Y., Ho, H. N. & Ling, T. Y., 2014, 於 : Molecular Human Reproduction. 20, 6, p. 526-537 12 p., gau016.

研究成果: 雜誌貢獻文章

Somatomedin Receptors
Stem Cells
Germ Cells
IGF Type 1 Receptor
Maintenance
5 引文 (Scopus)

Identification of trans, trans-2,4-Decadienal metabolites in mouse and human cells using liquid chromatography-mass spectrometry

Pan, K. L., Huang, W. J., Hsu, M. H., Lee, H. L., Liu, H. J., Cheng, C. W., Tsai, M. H., Shen, M. Y. & Lin, P., 十月 20 2014, 於 : Chemical Research in Toxicology. 27, 10, p. 1707-1719 13 p.

研究成果: 雜誌貢獻文章

Liquid chromatography
Metabolites
Liquid Chromatography
Mass spectrometry
Mass Spectrometry
14 引文 (Scopus)

Identifying association model for single-nucleotide polymorphisms of ORAI1 gene for breast cancer

Chang, W. C., Fang, Y. Y., Chang, H. W., Chuang, L. Y., Lin, Y. D., Hou, M. F. & Yang, C. H., 三月 31 2014, 於 : Cancer Cell International. 14, 1, 29.

研究成果: 雜誌貢獻文章

Single Nucleotide Polymorphism
Breast Neoplasms
Genes
Odds Ratio
Neoplasm Metastasis
12 引文 (Scopus)

IL-31 associated with coronary artery lesion formation in Kawasaki disease

Tseng, W. N., Lo, M. H., Guo, M. M. H., Hsieh, K. S., Chang, W. C. & Kuo, H. C., 八月 14 2014, 於 : PLoS One. 9, 8, e105195.

研究成果: 雜誌貢獻文章

Mucocutaneous Lymph Node Syndrome
Interleukins
coronary vessels
interleukins
Coronary Vessels
9 引文 (Scopus)

Increased risk of benign prostate hyperplasia in sleep apnea patients: A nationwide population-based study

Chou, P. S., Chang, W. C., Chou, W. P., Liu, M. E., Lai, C. L., Liu, C. K., Ku, Y. C., Tsai, S. J., Chou, Y. H. & Chang, W. P., 三月 25 2014, 於 : PLoS One. 9, 3, e93081.

研究成果: 雜誌貢獻文章

sleep apnea
Sleep Apnea Syndromes
hyperplasia
Hyperplasia
Prostate
9 引文 (Scopus)

Increased risk of pneumonia in patients receiving gonadotropin-releasing hormone agonists for prostate cancer

Chung, S. D., Liu, S. P., Lin, H. C. & Wang, L. H., 六月 27 2014, 於 : PLoS One. 9, 6, e101254.

研究成果: 雜誌貢獻文章

hormone agonists
prostatic neoplasms
gonadotropin-releasing hormone
Gonadotropin-Releasing Hormone
pneumonia
25 引文 (Scopus)

Increased risk of stroke among patients with ankylosing spondylitis: A population-based matched-cohort study

Keller, J. J., Shiu, R-L., Lin, S. M., Chou, C. C., Wang, L. H., Wang, J., Bai, C. H. & Chiou, H. Y., 2014, 於 : Rheumatology International. 34, 2, p. 255-263 9 p.

研究成果: 雜誌貢獻文章

Ankylosing Spondylitis
Cohort Studies
Stroke
Population
Taiwan
9 引文 (Scopus)

Increased risk of stroke among patients with ulcerative colitis: A population-based matched cohort study

Keller, J. J., Wang, J., Huang, Y. L., Chou, C. C., Wang, L. H., Shiu, R-L., Bai, C. H. & Chiou, H. Y., 2014, 於 : International Journal of Colorectal Disease. 29, 7, p. 805-812 8 p.

研究成果: 雜誌貢獻文章

Ulcerative Colitis
Cohort Studies
Stroke
Inflammatory Bowel Diseases
Population