• No. 250 Wu-Xing Street

    11031 Taipei

研究成果 1985 2020

2017
52 引文 (Scopus)

Resveratrol-induced autophagy and apoptosis in cisplatin-resistant human oral cancer CAR cells: A key role of AMPK and Akt/mTOR signaling

Chang, C. H., Lee, C. Y., Lu, C. C., Tsai, F. J., Hsu, Y. M., Tsao, J. W., Juan, Y. N., Chiu, H. Y., Yang, J. S. & Wang, C. C., 三月 1 2017, 於 : International Journal of Oncology. 50, 3, p. 873-882 10 p.

研究成果: 雜誌貢獻文章

AMP-Activated Protein Kinases
Mouth Neoplasms
Autophagy
Cisplatin
Apoptosis
9 引文 (Scopus)
Carbolines
Histone Deacetylases
Cytotoxicity
Hydroxamic Acids
Indoles
88 引文 (Scopus)

Robust multifunctional superhydrophobic coatings with enhanced water/oil separation, self-cleaning, anti-corrosion, and anti-biological adhesion

Cho, E. C., Chang-Jian, C. W., Chen, H. C., Chuang, K. S., Zheng, J. H., Hsiao, Y. S., Lee, K. C. & Huang, J. H., 2017, 於 : Chemical Engineering Journal. 314, p. 347-357 11 p.

研究成果: 雜誌貢獻文章

adhesion
corrosion
Cleaning
coating
Oils
1 引文 (Scopus)

rs2841277 (PLD4) is associated with susceptibility and rs4672495 is associated with disease activity in rheumatoid arthritis

Chen, W. C., Wang, W. C., Lu, H. F., Okada, Y., Chang, W. P., Chou, Y. H., Chang, H. H., Huang, J. D., Chen, D. Y. & Chang, W. C., 2017, 於 : Oncotarget. 8, 38, p. 64180-64190 11 p.

研究成果: 雜誌貢獻文章

Phospholipase D
Rheumatoid Arthritis
Ankylosing Spondylitis
Single Nucleotide Polymorphism
Genome-Wide Association Study
3 引文 (Scopus)

rs657075 (CSF2) is associated with the disease phenotype (BAS-G) of ankylosing spondylitis

Chen, W. C., Wei, J. C. C., Lu, H. F., Wong, H. S. C., Woon, P. Y., Hsu, Y. W., Huang, J. D. & Chang, W. C., 一月 3 2017, 於 : International Journal of Molecular Sciences. 18, 1, 83.

研究成果: 雜誌貢獻文章

phenotype
Ankylosing Spondylitis
Baths
baths
polymorphism
11 引文 (Scopus)

Sensitive screening of abused drugs in dried blood samples using ultra-high-performance liquid chromatography-ion booster-quadrupole time-of-flight mass spectrometry

Chepyala, D., Tsai, I. L., Liao, H. W., Chen, G. Y., Chao, H. C. & Kuo, C. H., 三月 31 2017, 於 : Journal of Chromatography A. 1491, p. 57-66 10 p.

研究成果: 雜誌貢獻文章

Preclinical Drug Evaluations
High performance liquid chromatography
Mass spectrometry
Mass Spectrometry
Screening
4 引文 (Scopus)

S -Nitrosothiols (SNO) as light-responsive molecular activators for post-synthesis fluorescence augmentation in fluorophore-loaded nanospheres

Lin, S. Y., Wang, M. R., Chiu, S. J., Lin, C. Y. & Hu, T. M., 一月 1 2017, 於 : Journal of Materials Chemistry B. 6, 1, p. 153-164 12 p.

研究成果: 雜誌貢獻文章

S-Nitrosothiols
Fluorophores
Nanospheres
Fluorescence
Nanoparticles
9 引文 (Scopus)

Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O6-methylguanine-DNA methyltransferase

Chang, K. Y., Hsu, T. I., Hsu, C. C., Tsai, S. Y., Liu, J. J., Chou, S. W., Liu, M. S., Liou, J. P., Ko, C. Y., Chen, K. Y., Hung, J. J., Chang, W. C., Chuang, C. K., Kao, T. J. & Chuang, J. Y., 十月 1 2017, 於 : Redox Biology. 13, p. 655-664 10 p.

研究成果: 雜誌貢獻文章

temozolomide
Methyltransferases
Glioblastoma
DNA
Proteins
4 引文 (Scopus)

Store-operated Ca2+ Entry Facilitates the Lipopolysaccharide-induced Cyclooxygenase-2 Expression in Gastric Cancer Cells

Wong, J. H., Ho, K. H., Nam, S., Hsu, W. L., Lin, C. H., Chang, C. M., Wang, J. Y. & Chang, W. C., 十二月 1 2017, 於 : Scientific Reports. 7, 1, 21813.

研究成果: 雜誌貢獻文章

Cyclooxygenase 2
Stomach Neoplasms
Lipopolysaccharides
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinase 1
20 引文 (Scopus)

Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability for in Vivo Gene Silencing in Leukemia

Lee, D. J., Kessel, E., Lehto, T., Liu, X., Yoshinaga, N., Padari, K., Chen, Y. C., Kempter, S., Uchida, S., Rädler, J. O., Pooga, M., Sheu, M. T., Kataoka, K. & Wagner, E., 九月 20 2017, 於 : Bioconjugate Chemistry. 28, 9, p. 2393-2409 17 p.

研究成果: 雜誌貢獻文章

Gene Silencing
RNA
Small Interfering RNA
Polyethylene glycols
Leukemia

The apoptotic mechanisms of MT-6, a mitotic arrest inducer, in human ovarian cancer cells

Chen, M. C., Kuo, Y. C., Hsu, C. M., Chen, Y. L., Shen, C. C., Teng, C. M. & Pan, S. L., 四月 7 2017, 於 : Scientific Reports. 7, 46149.

研究成果: 雜誌貢獻文章

Ovarian Neoplasms
Apoptosis
Mitochondrial Membrane Potential
G2 Phase
G1 Phase
4 引文 (Scopus)

The Association Between the Use of Zolpidem and the Risk of Alzheimer's Disease Among Older People

Cheng, H. T., Lin, F. J., Erickson, S. R., Hong, J. L. & Wu, C. H., 十一月 1 2017, 於 : Journal of the American Geriatrics Society. 65, 11, p. 2488-2495 8 p.

研究成果: 雜誌貢獻文章

Alzheimer Disease
Taiwan
zolpidem
Propensity Score
National Health Programs
9 引文 (Scopus)

The effect of wetting property on electrochromic properties offunctionalized poly(3,4-ethylenedioxythiophene) films

Cho, E. C., Chang-Jian, C. W., Ho, B. C., Yu, C. C., Hsiao, Y. S., Lee, K. C. & Huang, J. H., 十月 1 2017, 於 : Dyes and Pigments. 145, p. 95-102 8 p.

研究成果: 雜誌貢獻文章

Wetting
Moisture
Derivatives
Radiation counters
Redox reactions
13 引文 (Scopus)

The inhibition of lung cancer cell migration by AhR-regulated autophagy

Tsai, C. H., Li, C. H., Cheng, Y. W., Lee, C. C., Liao, P. L., Lin, C. H., Huang, S. H. & Kang, J. J., 二月 14 2017, 於 : Scientific Reports. 7, 41927.

研究成果: 雜誌貢獻文章

Aryl Hydrocarbon Receptors
Autophagy
Cell Movement
Lung Neoplasms
Epithelial-Mesenchymal Transition
14 引文 (Scopus)
Methylnitrosourea
Photoreceptor Cells
Apoptosis
Retinitis Pigmentosa
Cassia
5 引文 (Scopus)
Matrix Metalloproteinase 9
inhibitors
Lipopolysaccharides
interleukins
necrosis
1 引文 (Scopus)

Total synthesis and metabolic stability of hispidulin and its d-labelled derivative

Chen, L. C., Hsu, K. C., Chiou, L. C., Tseng, H. J. & Huang, W. J., 十一月 1 2017, 於 : Molecules. 22, 11, 1897.

研究成果: 雜誌貢獻文章

Derivatives
central nervous system
synthesis
liver
flavone
2 引文 (Scopus)
Stilbenes
Rhizome
Glycosides
Metabolites
Oxidation
3 引文 (Scopus)

Toxic Metals Increase Serum Tumor Necrosis Factor-α Levels, Modified by Essential Elements and Different Types of Tumor Necrosis Factor-α Promoter Single-nucleotide Polymorphisms

Huang, Y. C., Chang, W. C., Shan, Y. H., Lin, C. Y., Wang, C. L., Dai, C. Y., Ho, C. K., Wu, M. T. & Chuang, H. Y., 十月 1 2017, 於 : Epidemiology (Cambridge, Mass.). 28, p. S113-S120

研究成果: 雜誌貢獻文章

Poisons
Single Nucleotide Polymorphism
Tumor Necrosis Factor-alpha
Metals
Serum
2 引文 (Scopus)

Toxicological effects of NCKU-21, a phenanthrene derivative, on cell growth and migration of A549 and CL1-5 human lung adenocarcinoma cells

Liao, H. F., Pan, C. H., Chou, P. Y., Chen, Y. F., Wu, T. S., Sheu, M. J. & Wu, C. H., 九月 1 2017, 於 : PLoS One. 12, 9, e0185021.

研究成果: 雜誌貢獻文章

phenanthrene
Cell growth
adenocarcinoma
cell movement
Toxicology
Health Surveys
Pregnant Women
Interviews
3 引文 (Scopus)

V-J combinations of T-cell receptor predict responses to erythropoietin in end-stage renal disease patients

Chang, W. C., Wong, H. S. C., Chang, C. M., Kao, C. C., Hsu, Y. W., Liu, X., Chang, W. C. & Wu, M. S., 七月 11 2017, 於 : Journal of Biomedical Science. 24, 1, 43.

研究成果: 雜誌貢獻文章

Erythropoietin
T-Cell Antigen Receptor
Chronic Kidney Failure
Anemia
Erythrocyte Count
8 引文 (Scopus)
Histone Deacetylase Inhibitors
Cell Death
Breast Neoplasms
Heterografts
Genetic Promoter Regions
2016
12 引文 (Scopus)

2,3,5,4′-tetrahydroxystilbene-2-O- β -glucoside isolated from Polygoni Multiflori ameliorates the development of periodontitis

Chin, Y. T., Hsieh, M. T., Lin, C. Y., Kuo, P. J., Yang, Y. C. S. H., Shih, Y. J., Lai, H. Y., Cheng, G. Y., Tang, H. Y., Lee, C. C., Lee, S. Y., Wang, C. C., Lin, H. Y., Fu, E., Whang-Peng, J. & Liu, L. F., 2016, 於 : Mediators of Inflammation. 2016, 6953459.

研究成果: 雜誌貢獻文章

Porphyromonas gingivalis
Periodontitis
Ligation
Lipopolysaccharides
AMP-Activated Protein Kinases
5 引文 (Scopus)

2-(Phenylsulfonyl)quinoline N-hydroxyacrylamides as potent anticancer agents inhibiting histone deacetylase

Lee, H. Y., Chang, C. Y., Su, C. J., Huang, H. L., Mehndiratta, S., Chao, Y. H., Hsu, C. M., Kumar, S., Sung, T. Y., Huang, Y. Z., Li, Y. H., Yang, C. R. & Liou, J. P., 十月 21 2016, 於 : European Journal of Medicinal Chemistry. 122, p. 92-101 10 p.

研究成果: 雜誌貢獻文章

Histone Deacetylases
Antineoplastic Agents
Acetylation
Acrylamide
Structure-Activity Relationship
13 引文 (Scopus)

Alterations in histone deacetylase 8 lead to cell migration and poor prognosis in breast cancer

Hsieh, C. L., Ma, H. P., Su, C-M., Chang, Y. J., Hung, W. Y., Ho, Y. S., Huang, W. J. & Lin, R. K., 四月 15 2016, 於 : Life Sciences. 151, p. 7-14 8 p.

研究成果: 雜誌貢獻文章

Histone Deacetylases
Cell Movement
Breast Neoplasms
Atlases
Assays
18 引文 (Scopus)

Angiogenesis Inhibitors and Anti-Inflammatory Agents from Phoma sp. NTOU4195

Lee, M. S., Wang, S. W., Wang, G. J., Pang, K. L., Lee, C. K., Kuo, Y. H., Cha, H. J., Lin, R. K. & Lee, T. H., 十二月 23 2016, 於 : Journal of Natural Products. 79, 12, p. 2983-2990 8 p.

研究成果: 雜誌貢獻文章

Angiogenesis Inhibitors
Macrophages
Endothelial cells
Inhibitory Concentration 50
Lipopolysaccharides
3 引文 (Scopus)

A novel tubulin polymerization inhibitor, MPT0B206, downregulates Bcr-Abl expression and induces apoptosis in imatinib-sensitive and imatinib-resistant CML cells

Chen, C. W., Lee, Y. L., Liou, J. P., Liu, Y. H., Liu, C. W., Chen, T. Y. & Huang, H. M., 九月 1 2016, 於 : Apoptosis. 21, 9, p. 1008-1018 11 p.

研究成果: 雜誌貢獻文章

Tubulin Modulators
K562 Cells
Myeloid Cells
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Down-Regulation
6 引文 (Scopus)

Anticataractogenesis Mechanisms of Curcumin and a Comparison of Its Degradation Products: An in Vitro Study

Liao, J. H., Huang, Y. S., Lin, Y. C., Huang, F. Y., Wu, S. H. & Wu, T. H., 三月 16 2016, 於 : Journal of Agricultural and Food Chemistry. 64, 10, p. 2080-2086 7 p.

研究成果: 雜誌貢獻文章

Curcumin
curcumin
in vitro studies
Degradation
ferulic acid
25 引文 (Scopus)

Anti-inflammatory and Antinociceptive Constituents of Atractylodes japonica Koidzumi

Chen, L. G., Jan, Y. S., Tsai, P. W., Norimoto, H., Michihara, S., Murayama, C. & Wang, C. C., 三月 23 2016, 於 : Journal of Agricultural and Food Chemistry. 64, 11, p. 2254-2262 9 p.

研究成果: 雜誌貢獻文章

Atractylodes
Atractylodes lancea
lipopolysaccharides
Anti-Inflammatory Agents
anti-inflammatory activity
3 引文 (Scopus)

Anti-MMP-2 Activity and Skin-Penetrating Capability of the Chemical Constituents from Rhodiola rosea

Lee, T-H., Hsu, C. C., Hsiao, G., Fang, J. Y., Liu, W. M. & Lee, C. K., 五月 1 2016, 於 : Planta Medica. 82, 8, p. 698-704

研究成果: 雜誌貢獻文章

Rhodiola
Matrix Metalloproteinase 2
Matrix Metalloproteinases
Skin
Collagenases
19 引文 (Scopus)

Antinociceptive and anti-inflammatory effects of zerumbone against mono-iodoacetate-induced arthritis

Chien, T. Y., Huang, S. K. H., Lee, C. J., Tsai, P. W. & Wang, C. C., 二月 1 2016, 於 : International Journal of Molecular Sciences. 17, 2, 249.

研究成果: 雜誌貢獻文章

Iodoacetates
arthritis
Nitric oxide
nitric oxide
Arthritis
1 引文 (Scopus)

Antiobesity and antihyperlipidaemic effects of Yan-Sheng-Yin in animals and humans

Wu, C. H., Pan, C. H., Lee, C. K., Sheu, M. J., Liu, F. C., Wang, G. J. & Wu, C. H., 六月 1 2016, 於 : Journal of Functional Foods. 24, p. 173-182 10 p.

研究成果: 雜誌貢獻文章

Hypolipidemic Agents
atherogenesis
hyperlipidemia
Hyperlipidemias
Atherosclerosis
9 引文 (Scopus)

Application of plasma levels of olanzapine and N-desmethyl-olanzapine to monitor clinical efficacy in patients with schizophrenia

Lu, M. L., Wu, Y. X., Chen, C. H., Kuo, P. T., Chen, Y. H., Lin, C. H. & Wu, T. H., 二月 1 2016, 於 : PLoS One. 11, 2, e0148539.

研究成果: 雜誌貢獻文章

olanzapine
Schizophrenia
Plasmas
monitoring
dosage
2 引文 (Scopus)
Mucocutaneous Lymph Node Syndrome
Attention Deficit Disorder with Hyperactivity
Cohort Studies
Population
Confidence Intervals
17 引文 (Scopus)

A triterpenoid from wild bitter gourd inhibits breast cancer cells

Bai, L. Y., Chiu, C. F., Chu, P. C., Lin, W. Y., Chiu, S. J. & Weng, J. R., 三月 1 2016, 於 : Scientific Reports. 6, 22419.

研究成果: 雜誌貢獻文章

Momordica charantia
Breast Neoplasms
Peroxisome Proliferator-Activated Receptors
Histone Deacetylases
Autophagy

Bioinformatic analyses revealed underlying biological functions correlated with oxaliplatin responsiveness

Klahan, S., Huang, C. C., Chien, S-C., Wu, M. S., Wong, H. S. C., Huang, C. Y., Chang, W. C. & Wei, P. L., 一月 1 2016, 於 : Tumor Biology. 37, 1, p. 583-590

研究成果: 雜誌貢獻文章

oxaliplatin
Computational Biology
Colonic Neoplasms
Toll-Like Receptor 5
Therapeutics
5 引文 (Scopus)

Carboxyfullerene decorated titanium dioxide nanomaterials for reactive oxygen species scavenging activities

Yang, K. C., Zheng, J. H., Chen, Y. L., Lee, K. C. & Cho, E. C., 2016, 於 : RSC Advances. 6, 58, p. 53025-53033 9 p.

研究成果: 雜誌貢獻文章

Fullerenes
Scavenging
Nanostructured materials
Titanium dioxide
Reactive Oxygen Species
10 引文 (Scopus)

Characterization of cytokinome landscape for clinical responses in human cancers

Wong, H. S. C., Chang, C. M., Liu, X., Huang, W. C. & Chang, W. C., 十一月 1 2016, 於 : OncoImmunology. 5, 11, e1214789.

研究成果: 雜誌貢獻文章

Cytokines
Neoplasms
Chemokines
Down-Regulation
Biomarkers
2 引文 (Scopus)

Chemical Constituents from Termite-associated Xylaria acuminatilongissima YMJ623

Cho, T. Y., Wang, G. J., Ju, Y. M., Chen, M. C. & Lee, T. H., 五月 1 2016, 於 : Journal of the Chinese Chemical Society. 63, 5, p. 404-409 6 p.

研究成果: 雜誌貢獻文章

Lipopolysaccharides
Benzofurans
Optical rotation
Macrophages
Natural resources
24 引文 (Scopus)
docetaxel
Hydrogels
Micelles
Doxorubicin
Tumors
16 引文 (Scopus)
Triple Negative Breast Neoplasms
Histone Deacetylase Inhibitors
Autophagy
Down-Regulation
Ionizing Radiation
12 引文 (Scopus)

Development and Characterization of Lecithin-based Self-assembling Mixed Polymeric Micellar (saMPMs) Drug Delivery Systems for Curcumin

Chen, L. C., Chen, Y-C., Su, C. Y., Wong, W. P., Sheu, M-T. & Ho, H-O., 十一月 16 2016, 於 : Scientific Reports. 6, 37122.

研究成果: 雜誌貢獻文章

Curcumin
Lecithins
Drug Delivery Systems
Micelles
Biological Availability
17 引文 (Scopus)
Lecithin
Pharmacokinetics
Oncology
Lecithins
Quercetin
15 引文 (Scopus)

Early investigational tubulin inhibitors as novel cancer therapeutics

Nepali, K., Ojha, R., Lee, H. Y. & Liou, J. P., 八月 2 2016, 於 : Expert Opinion on Investigational Drugs. 25, 8, p. 917-936 20 p.

研究成果: 雜誌貢獻回顧型文獻

Tubulin Modulators
Microtubules
Clinical Trials
Taxoids
Neoplasms
27 引文 (Scopus)

Economic evaluations of pharmacist-managed services in people with diabetes mellitus: A systematic review

Wang, Y., Yeo, Q. Q. & Ko, Y., 四月 1 2016, 於 : Diabetic Medicine. 33, 4, p. 421-427 7 p.

研究成果: 雜誌貢獻文章

Pharmacists
Cost-Benefit Analysis
Diabetes Mellitus
Economics
Health
6 引文 (Scopus)

Effects of Dang-Gui-Bu-Xue-Tang, an herbal decoction, on iron uptake in iron-deficient anemia

Huang, G. C., Chen, S. Y., Tsai, P. W., Ganzon, J. G., Lee, C. J., Shiah, H. S. & Wang, C. C., 三月 2 2016, 於 : Drug Design, Development and Therapy. 10, p. 949-957 9 p.

研究成果: 雜誌貢獻文章

ferrous sulfate
Anemia
Iron
Hemoglobins
Caco-2 Cells
2 引文 (Scopus)

Effects of different forages on the chemical compositions and antiosteoporotic activities of velvet antlers

Tseng, S. H., Chen, L. G., Lai, Y. J., Wang, K. T. & Wang, C. C., 八月 1 2016, 於 : Animal science journal = Nihon chikusan Gakkaiho. 87, 8, p. 989-996 8 p.

研究成果: 雜誌貢獻文章

velvet antlers
Antlers
chemical composition
forage
hay
14 引文 (Scopus)

Gene expression profiling combined with functional analysis identify integrin beta1 (ITGB1) as a potential prognosis biomarker in triple negative breast cancer

Klahan, S., Huang, W. C., Chang, C. M., Wong, H. S. C., Huang, C. C., Wu, M. S., Lin, Y. C., Lu, H. F., Hou, M. F. & Chang, W. C., 二月 1 2016, 於 : Pharmacological Research. 104, p. 31-37 7 p.

研究成果: 雜誌貢獻文章

CD29 Antigens
Triple Negative Breast Neoplasms
Gene Expression Profiling
Biomarkers
Breast Neoplasms
68 引文 (Scopus)

Graphene-based thermoplastic composites and their application for LED thermal management

Cho, E. C., Huang, J. H., Li, C. P., Chang-Jian, C. W., Lee, K. C., Hsiao, Y. S. & Huang, J. H., 六月 1 2016, 於 : Carbon. 102, p. 66-73 8 p.

研究成果: 雜誌貢獻文章

Graphite
Nylons
Polyamides
Graphene
Thermoplastics