• No. 250 Wu-Xing Street

    11031 Taipei

研究成果 1985 2020

2018

Metabolic profiling of metformin treatment for low-level Pb-induced nephrotoxicity in rat urine

Huang, Y. S., Wang, S. H., Chen, S. M. & Lee, J. A., 十二月 1 2018, 於 : Scientific Reports. 8, 1, 14587.

研究成果: 雜誌貢獻文章

Metformin
Biomarkers
Aminolevulinic Acid
Urine
Lactic Acid
9 引文 (Scopus)
metformin
Metformin
renal function
Medical problems
diabetes mellitus

Method development of immunoglobulin G purification from micro-volumes of human serum for untargeted and targeted proteomics-based antibody repertoire studies

Chang, Y. T., Chang, M. C., Tsai, Y. J., Ferng, C., Shih, H. C., Kuo, Y. P., Chen, C. H. & Tsai, I. L., 一月 1 2018, (接受/付印) 於 : Journal of Food and Drug Analysis.

研究成果: 雜誌貢獻文章

immunoglobulin G
Proteomics
proteomics
Immunoglobulin G
purification methods
6 引文 (Scopus)

Microwave-assisted synthesis of TiO2/WS2 heterojunctions with enhanced photocatalytic activity

Cho, E. C., Chang-Jian, C. W., Zheng, J. H., Huang, J. H., Lee, K. C., Ho, B. C. & Hsiao, Y. S., 十月 1 2018, 於 : Journal of the Taiwan Institute of Chemical Engineers. 91, p. 489-498 10 p.

研究成果: 雜誌貢獻文章

Heterojunctions
Microwaves
Photocatalysts
Light absorption
Light emitting diodes
2 引文 (Scopus)

miR-4725-3p targeting stromal interacting molecule 1 signaling is involved in xanthohumol inhibition of glioma cell invasion

Ho, K. H., Chang, C. K., Chen, P. H., Wang, Y. J., Chang, W. C. & Chen, K. C., 八月 1 2018, 於 : Journal of Neurochemistry. 146, 3, p. 269-288 20 p.

研究成果: 雜誌貢獻文章

Glioma
Molecules
Glioblastoma
Humulus
Tumors
5 引文 (Scopus)

Nano-Diamino-Tetrac (NDAT) Enhances Resveratrol-Induced Antiproliferation by Action on the RRM2 Pathway in Colorectal Cancers

Nana, A. W., Wu, S. Y., Yang, Y. C. S., Chin, Y. T., Cheng, T. M., Ho, Y., Li, W. S., Liao, Y. M., Chen, Y. R., Shih, Y. J., Liu, Y. R., Pedersen, J., Incerpi, S., Hercbergs, A., Liu, L. F., Whang-Peng, J., Davis, P. J. & Lin, H. Y., 十月 1 2018, 於 : Hormones and Cancer. 9, 5, p. 349-360 12 p.

研究成果: 雜誌貢獻文章

Colorectal Neoplasms
Oxidoreductases
Neoplasms
Integrins
Stilbenes
7 引文 (Scopus)

Nano-diamino-tetrac (NDAT) inhibits PD-L1 expression which is essential for proliferation in oral cancer cells

Lin, S. J., Chin, Y. T., Ho, Y., Chou, S. Y., Sh Yang, Y. C., Nana, A. W., Su, K. W., Lim, Y. T., Wang, K., Lee, SY. Y., Shih, Y. J., Chen, Y. R., Whang-Peng, J., Davis, P. J., Lin, H. Y. & Fu, E., 十月 1 2018, 於 : Food and Chemical Toxicology. 120, p. 1-11 11 p.

研究成果: 雜誌貢獻文章

Mouth Neoplasms
Cells
death
Ligands
phosphatidylinositol 3-kinase
2 引文 (Scopus)

New Hirsutinolide-Type Sesquiterpenoids from Vernonia cinerea Inhibit Nitric Oxide Production in LPS-Stimulated RAW264.7 Cells

Kuo, L. M. Y., Tseng, P. Y., Lin, Y. C., Liaw, C. C., Zhang, L. J., Tsai, K. C., Lin, Z. H., Ho, H. O. & Kuo, Y. H., 七月 9 2018, (接受/付印) 於 : Planta Medica.

研究成果: 雜誌貢獻文章

Vernonia
Phytochemicals
Structure-Activity Relationship
Nitric Oxide
Esters

New terpenoids from Chamaecyparis formosensis (Cupressaceae) leaves with modulatory activity on matrix metalloproteases 2 and 9

Chang, M. L., Mei, H. C., Kuo, I. C., Hsiao, G., Kuo, Y. H. & Lee, C. K., 三月 7 2018, 於 : Molecules. 23, 3, 604.

研究成果: 雜誌貢獻文章

Chamaecyparis
Cupressaceae
Terpenes
Metalloproteases
leaves
6 引文 (Scopus)
docetaxel
Poloxamer
Lecithins
Ovarian Neoplasms
Cisplatin
2 引文 (Scopus)
Hypoxia-Inducible Factor 1
Phosphorylation
Epithelial-Mesenchymal Transition
Transforming Growth Factors
Microtubules
1 引文 (Scopus)
Cistanche
Light
Retinal Pigments
Staining and Labeling
Phototoxic Dermatitis

Patient preferences for diabetes-related complications in Taiwan

Lin, Y. J., Wang, C. Y., Cheng, S. W. & Ko, Y., 五月 25 2018, (接受/付印) 於 : Current Medical Research and Opinion. p. 1-7 7 p.

研究成果: 雜誌貢獻文章

Patient Preference
Diabetes Complications
Taiwan
Diabetes Mellitus
Visual Analog Scale
2 引文 (Scopus)

Proteomics analysis of altered proteins in kidney of mice with aristolochic acid nephropathy using the fluorogenic derivatization-liquid chromatography-tandem mass spectrometry method

Lin, C. E., Chang, W. S., Lee, J. A., Chang, T. Y., Huang, Y. S., Hirasaki, Y., Chen, H. S., Imai, K. & Chen, S. M., 三月 1 2018, 於 : Biomedical Chromatography. 32, 3, p. e4127

研究成果: 雜誌貢獻文章

Liquid chromatography
Tandem Mass Spectrometry
Liquid Chromatography
Proteomics
Mass spectrometry

Quantitative contributions of processes by which polyanion drugs reduce intracellular bioavailability and transfection efficiency of cationic siRNA lipoplex

Jaiprasart, P., Yeung, B. Z., Lu, Z., Wientjes, M. G., Cui, M., Hsieh, C. M., Woo, S. & Au, J. L. S., 一月 28 2018, 於 : Journal of Controlled Release. 270, p. 101-113 13 p.

研究成果: 雜誌貢獻文章

Small Interfering RNA
Biological Availability
Transfection
Suramin
Pharmaceutical Preparations
1 引文 (Scopus)
ephedrine
Ephedrine
Taiwan
police
drugs
10 引文 (Scopus)

Resveratrol induces sumoylated COX-2-dependent anti-proliferation in human prostate cancer LNCaP cells

Cheng, T. M., Chin, Y. T., Ho, Y., Chen, Y. R., Yang, Y. N., Yang, Y. C., Shih, Y. J., Lin, T. I., Lin, H. Y. & Davis, P. J., 二月 1 2018, 於 : Food and Chemical Toxicology. 112, p. 67-75 9 p.

研究成果: 雜誌貢獻文章

resveratrol
prostatic neoplasms
prostaglandin synthase
Cyclooxygenase 2
Prostatic Neoplasms
6 引文 (Scopus)

Resveratrol inhibits human leiomyoma cell proliferation via crosstalk between integrin αvβ3 and IGF-1R

Ho, Y., SH Yang, Y. C., Chin, Y. T., Chou, S. Y., Chen, Y. R., Shih, Y. J., Whang-Peng, J., Changou, C. A., Liu, H. L., Lin, S. J., Tang, H. Y., Lin, H. Y. & Davis, P. J., 十月 1 2018, 於 : Food and Chemical Toxicology. 120, p. 346-355 10 p.

研究成果: 雜誌貢獻文章

resveratrol
integrins
Myoma
Cell proliferation
somatomedins
1 引文 (Scopus)

Risk undermined in the bilateral pharmaceutical regulatory system in Taiwan

Wang, H. P. & Wang, C. L., 一月 1 2018, (接受/付印) 於 : Journal of Food and Drug Analysis.

研究成果: 雜誌貢獻文章

Pharmacovigilance
Taiwan
planning
medicine
drug therapy
11 引文 (Scopus)

ROS-independent ER stress-mediated NRF2 activation promotes warburg effect to maintain stemness-associated properties of cancer-initiating cells

Chang, C. W., Chen, Y. S., Tsay, Y. G., Han, C. L., Chen, Y. J., Yang, C. C., Hung, K. F., Lin, C. H., Huang, T. Y., Kao, S. Y., Lee, T. C. & Lo, J. F., 二月 1 2018, 於 : Cell Death and Disease. 9, 2, 194.

研究成果: 雜誌貢獻文章

Neoplasms
Maintenance
Acetyl Coenzyme A
Citric Acid Cycle
Neoplastic Stem Cells
5 引文 (Scopus)

S100A9+ MDSC and TAM-mediated EGFR-TKI resistance in lung adenocarcinoma: The role of RELB

Feng, P. H., Yu, C. T., Chen, K. Y., Luo, C. S., Wu, S. M., Liu, C. Y., Kuo, L. W., Chan, Y. F., Chen, T. T., Chang, C. C., Lee, C. N., Chuang, H. C., Lin, C. F., Han, C. L., Lee, W. H. & Lee, K. Y., 一月 26 2018, 於 : Oncotarget. 9, 7, p. 7631-7643 13 p.

研究成果: 雜誌貢獻文章

Protein-Tyrosine Kinases
Macrophages
Microarray Analysis
Blood Cells
Alveolar Macrophages
5 引文 (Scopus)

Safety assessment of the Cistanche tubulosa health food product Memoregain®: Genotoxicity and 28-day repeated dose toxicity test

Liao, P. L., Li, C. H., Tse, L. S., Kang, J. J. & Cheng, Y. W., 八月 1 2018, 於 : Food and Chemical Toxicology. 118, p. 581-588 8 p.

研究成果: 雜誌貢獻文章

Cistanche
Toxicity Tests
Salmonella
health foods
safety assessment
HSP27 Heat-Shock Proteins
Colorectal Neoplasms
Neoplasm Metastasis
Molecules
Proteins
5 引文 (Scopus)
Clustered Regularly Interspaced Short Palindromic Repeats
Polyethyleneimine
Cell death
Serum Albumin
Immunotherapy
6 引文 (Scopus)

Subcellular Proteome Landscape of Human Embryonic Stem Cells Revealed Missing Membrane Proteins

Weldemariam, M. M., Han, C-L., Shekari, F., Kitata, R. B., Chuang, C-Y., Hsu, W-T., Kuo, H-C., Choong, W-K., Sung, T-Y., He, F-C., Chung, M. C. M., Salekdeh, G. H. & Chen, Y-J., 十二月 7 2018, 於 : Journal of Proteome Research. 17, 12, p. 4138-4151 14 p.

研究成果: 雜誌貢獻文章

Proteome
Stem cells
Membrane Proteins
Proteins
Peptides
1 引文 (Scopus)
Antrodia
Cell growth
Drug Resistance
lungs
Cell Movement
3 引文 (Scopus)
Balloon Angioplasty
Vascular Smooth Muscle
Smooth Muscle Myocytes
Hyperplasia
Cell Movement
17 引文 (Scopus)

Ternary composite based on homogeneous Ni(OH)2 on graphene with Ag nanoparticles as nanospacers for efficient supercapacitor

Cho, E. C., Chang-Jian, C. W., Lee, K. C., Huang, J. H., Ho, B. C., Liu, R. Z. & Hsiao, Y. S., 二月 15 2018, 於 : Chemical Engineering Journal. 334, p. 2058-2067 10 p.

研究成果: 雜誌貢獻文章

Graphite
Oxides
Graphene
oxide
Nanoparticles
11 引文 (Scopus)

Tetrac downregulates β-catenin and HMGA2 to promote the effect of resveratrol in colon cancer

Nana, A. W., Chin, Y. T., Lin, C. Y., Ho, Y., Bennett, J. A., Shih, Y. J., Chen, Y. R., Changou, C. A., Pedersen, J. Z., Incerpi, S., Liu, L. F., Whang-Peng, J., Fu, E., Li, W. S., Mousa, S. A., Lin, H. Y. & Davis, P. J., 三月 1 2018, 於 : Endocrine-Related Cancer. 25, 3, p. 279-293 15 p.

研究成果: 雜誌貢獻文章

High Mobility Group Proteins
Catenins
varespladib methyl
Colonic Neoplasms
Down-Regulation
2 引文 (Scopus)

The anticancer effects of MPT0G211, a novel HDAC6 inhibitor, combined with chemotherapeutic agents in human acute leukemia cells

Tu, H. J., Lin, Y. J., Chao, M. W., Sung, T. Y., Wu, Y. W., Chen, Y. Y., Lin, M. H., Liou, J. P., Pan, S. L. & Yang, C. R., 十二月 29 2018, 於 : Clinical Epigenetics. 10, 1, 162.

研究成果: 雜誌貢獻文章

Leukemia
Vincristine
Doxorubicin
Drug Therapy
Neoplasms
6 引文 (Scopus)

The association between BDNF Val66Met polymorphism and emotional symptoms after mild traumatic brain injury

Wang, Y. J., Chen, K. Y., Kuo, L. N., Wang, W. C., Hsu, Y. W., Wong, H. S. C., Lin, C. M., Liao, K. H., Zhang, Y. F., Chiang, Y. H. & Chang, W. C., 一月 22 2018, 於 : BMC Medical Genetics. 19, 1, 13.

研究成果: 雜誌貢獻文章

Brain Concussion
Brain-Derived Neurotrophic Factor
Equipment and Supplies
Alleles
Depression
4 引文 (Scopus)
Uveitis
Endotoxins
Neuroglia
Microglia
Tumor Necrosis Factor-alpha
8 引文 (Scopus)
Glucosides
Doxorubicin
antioxidant
Antioxidants
Focal Segmental Glomerulosclerosis
15 引文 (Scopus)
Histone Acetyltransferases
Alzheimer Disease
Phosphorylation
Histone Deacetylases
tau Proteins
13 引文 (Scopus)

Thermally conductive polymeric composites incorporating 3D MWCNT/PEDOT: PSS scaffolds

Chang-Jian, C. W., Cho, E. C., Lee, K. C., Huang, J. H., Chen, P. Y., Ho, B. C. & Hsiao, Y. S., 三月 1 2018, 於 : Composites Part B: Engineering. 136, p. 46-54 9 p.

研究成果: 雜誌貢獻文章

Carbon Nanotubes
Scaffolds
Styrene
Carbon nanotubes
Composite materials
18 引文 (Scopus)

Thyroxine inhibits resveratrol-caused apoptosis by PD-L1 in ovarian cancer cells

Chin, Y. T., Wei, P. L., Ho, Y., Nana, A. W., Changou, C. A., Chen, Y. R., Yang, Y. C. SH., Hsieh, M. T., Hercbergs, A., Davis, P. J., Shih, Y. J. & Lin, H. Y., 五月 1 2018, 於 : Endocrine-Related Cancer. 25, 5, p. 533-545 13 p.

研究成果: 雜誌貢獻文章

Cyclooxygenase 2
Thyroxine
Ovarian Neoplasms
Apoptosis
Ligands
3 引文 (Scopus)
Transforming Growth Factor alpha
Epithelial-Mesenchymal Transition
Colonic Neoplasms
Assays
Carcinogenesis
1 引文 (Scopus)
Type 2 Diabetes Mellitus
chronic illness
Hypoglycemic Agents
drug
Taiwan
1 引文 (Scopus)

Upregulation of Znf179 acetylation by SAHA protects cells against oxidative stress

Wu, C. C., Lee, P. T., Kao, T. J., Chou, S. Y., Su, R. Y., Lee, Y. C., Yeh, S. H., Liou, J. P., Hsu, T. I., Su, T. P., Chuang, C. K., Chang, W. C. & Chuang, J. Y., 十月 1 2018, 於 : Redox Biology. 19, p. 74-80 7 p.

研究成果: 雜誌貢獻文章

Acetylation
Oxidative stress
Zinc Fingers
Zinc
Oxidative Stress
1 引文 (Scopus)
Students
Education
Aptitude
Prescriptions
Curricula
9 引文 (Scopus)

β-Amyloid Induces Pathology-Related Patterns of Tau Hyperphosphorylation at Synaptic Terminals

Wu, H-Y., Kuo, P-C., Wang, Y-T., Lin, H-T., Roe, A. D., Wang, B. Y., Han, C-L., Hyman, B. T., Chen, Y-J. & Tai, H-C., 九月 1 2018, 於 : Journal of Neuropathology and Experimental Neurology. 77, 9, p. 814-826 13 p.

研究成果: 雜誌貢獻文章

Presynaptic Terminals
Amyloid
Phosphotransferases
Proline
Pathology
2017
2 引文 (Scopus)

1,4-Naphthoquinones as inhibitors of Itch, a HECT domain-E3 ligase, and tumor growth suppressors in multiple myeloma

Liu, Y. M., HuangFu, W. C., Huang, H. L., Wu, W. C., Chen, Y. L., Yen, Y., Huang, H. L., Nien, C. Y., Lai, M. J., Pan, S. L. & Liou, J. P., 十一月 10 2017, 於 : European Journal of Medicinal Chemistry. 140, p. 84-91 8 p.

研究成果: 雜誌貢獻文章

Ubiquitin-Protein Ligases
Multiple Myeloma
Tumors
Lead compounds
Growth
9 引文 (Scopus)

3-Aroylindoles display antitumor activity in vitro and in vivo: Effects of N1-substituents on biological activity

Lee, H-Y., Lee, J. F., Kumar, S., Wu, Y. W., HuangFu, W-C., Lai, M-J., Li, Y-H., Huang, H. L., Kuo, F. C., Hsiao, C. J., Cheng, C. C., Yang, C. R. & Liou, J-P., 一月 5 2017, 於 : European Journal of Medicinal Chemistry. 125, p. 1268-1278 11 p.

研究成果: 雜誌貢獻文章

Histone Deacetylases
Tubulin
Bioactivity
Hydroxamic Acids
Tubulin Modulators
8 引文 (Scopus)

4-Indolyl-N-hydroxyphenylacrylamides as potent HDAC class I and IIB inhibitors in vitro and in vivo

Mehndiratta, S., Wang, R. S., Huang, H. L., Su, C. J., Hsu, C. M., Wu, Y. W., Pan, S. L. & Liou, J. P., 七月 7 2017, 於 : European Journal of Medicinal Chemistry. 134, p. 13-23 11 p.

研究成果: 雜誌貢獻文章

Heterografts
Tumors
Bearings (structural)
Histone Deacetylase Inhibitors
Acrylamide
4 引文 (Scopus)

Accumulation of methylglyoxal and d-lactate in Pb-induced nephrotoxicity in rats

Huang, Y. S., Li, Y. C., Tsai, P. Y., Lin, C. E., Chen, C. M., Chen, S-M. & Lee, J-A., 五月 2017, 於 : Biomedical Chromatography.

研究成果: 雜誌貢獻文章

Pyruvaldehyde
Metformin
Rats
Lactic Acid
Kidney
9 引文 (Scopus)

A histone deacetylase inhibitor enhances expression of genes inhibiting Wnt pathway and augments activity of DNA demethylation reagent against nonsmall-cell lung cancer

Shieh, J. M., Tang, Y. A., Hu, F. H., Huang, W. J., Wang, Y. J., Jen, J., Liao, S. Y., Lu, Y. H., Yeh, Y. L., Wang, T. W., Lin, P. & Wang, Y. C., 五月 15 2017, 於 : International Journal of Cancer. 140, 10, p. 2375-2386 12 p.

研究成果: 雜誌貢獻文章

decitabine
Wnt Signaling Pathway
Histone Deacetylase Inhibitors
Histone Deacetylases
Non-Small Cell Lung Carcinoma
11 引文 (Scopus)

Allopurinol, benzbromarone and risk of coronary heart disease in gout patients: A population-based study

Lin, H. C., Daimon, M., Wang, C. H., Ho, Y., Uang, Y. S., Chiang, S. J. & Wang, L. H., 四月 15 2017, 於 : International Journal of Cardiology. 233, p. 85-90 6 p.

研究成果: 雜誌貢獻文章

Gout
Coronary Disease
Coronary Artery Disease
Benzbromarone
Population
2 引文 (Scopus)
Colistin
Mass spectrometry
Mass Spectrometry
Blood
Prodrugs
3 引文 (Scopus)

An oral quinoline derivative, MPT0B392, causes leukemic cells mitotic arrest and overcomes drug resistant cancer cells

Chao, M. W., Huang, H. L., HuangFu, W. C., Hsu, K. C., Liu, Y. M., Wu, Y. W., Lin, C. F., Chen, Y. L., Lai, M. J., Lee, H. Y., Liou, J. P., Teng, C. M. & Yang, C. R., 2017, 於 : Oncotarget. 8, 17, p. 27772-27785 14 p.

研究成果: 雜誌貢獻文章

Leukemia
Pharmaceutical Preparations
Neoplasms
Glycoproteins
National Cancer Institute (U.S.)
6 引文 (Scopus)

A novel histone deacetylase inhibitor TMU-35435 enhances etoposide cytotoxicity through the proteasomal degradation of DNA-PKcs in triple-negative breast cancer

Wu, Y. H., Hong, C. W., Wang, Y. C., Huang, W. J., Yeh, Y. L., Wang, B. J., Wang, Y. J. & Chiu, H. W., 八月 1 2017, 於 : Cancer Letters. 400, p. 79-88 10 p.

研究成果: 雜誌貢獻文章

DNA-Activated Protein Kinase
Triple Negative Breast Neoplasms
Histone Deacetylase Inhibitors
Etoposide
DNA Repair