• No. 250 Wu-Xing Street

    11031 Taipei

研究成果 1985 2020

2018
3 引文 (Scopus)

A novel dual HDAC6 and tubulin inhibitor, MPT0B451, displays anti-tumor ability in human cancer cells in vitro and in vivo

Wu, Y. W., Hsu, K. C., Lee, H. Y., Huang, T. C., Lin, T. E., Chen, Y. L., Sung, T. Y., Liou, J. P., Hwang-Verslues, W. W., Pan, S. L. & HuangFu, W. C., 三月 13 2018, 於 : Frontiers in Pharmacology. 9, MAR, 205.

研究成果: 雜誌貢獻文章

Tubulin Modulators
Histone Deacetylases
Neoplasms
Tubulin
Molecular Docking Simulation
2 引文 (Scopus)

A novel hydroxamate-based compound WMJ-J-09 causes head and neck squamous cell carcinoma cell death via LKB1-AMPK-p38MAPK-p63-survivin cascade

Yen, C. S., Choy, C. S., Huang, W. J., Huang, S. W., Lai, P. Y., Yu, M. C., Shiue, C., Hsu, Y. F. & Hsu, M. J., 三月 1 2018, 於 : Frontiers in Pharmacology. 9, MAR, p. 1-17 17 p., 167.

研究成果: 雜誌貢獻文章

p38 Mitogen-Activated Protein Kinases
Cell Death
Microtubules
Liver
Phosphorylation
8 引文 (Scopus)
olanzapine
Schizophrenia
Drug Monitoring
C-Peptide
Waist Circumference
9 引文 (Scopus)
NF-kappa B
Magnetic resonance
Reporter Genes
Nanoparticles
Lung Neoplasms
2 引文 (Scopus)

Association between nonsteroidal anti-inflammatory drugs and atrial fibrillation among a middle-aged population: A nationwide population-based cohort

Chuang, S. Y., Hsu, P. F., Lin, F. J., Huang, Y. W., Wang, G. Z., Chang, W. C. & Tsai, H. J., 一月 1 2018, (接受/付印) 於 : British Journal of Clinical Pharmacology.

研究成果: 雜誌貢獻文章

Atrial Fibrillation
Anti-Inflammatory Agents
Pharmaceutical Preparations
Population
Odds Ratio
3 引文 (Scopus)

Association between nonsteroidal anti-inflammatory drugs and colorectal cancer: A population-based case-control study

Kuo, C. N., Pan, J. J., Huang, Y. W., Tsai, H. J. & Chang, W. C., 七月 1 2018, 於 : Cancer Epidemiology Biomarkers and Prevention. 27, 7, p. 737-745 9 p.

研究成果: 雜誌貢獻文章

Case-Control Studies
Colorectal Neoplasms
Anti-Inflammatory Agents
Pharmaceutical Preparations
Population
6 引文 (Scopus)
docetaxel
Bispecific Antibodies
Lecithins
Drug Delivery Systems
Neoplasms

Bradycardia and hypotension from improper use of aconite root: A case report and brief review

Chou, P. Y., Wang, C. C., Tai, C. J., Yang, T. L. & Tang, Y. J., 十月 1 2018, 於 : Complementary Medicine Research. 25, 5, p. 338-343 6 p.

研究成果: 雜誌貢獻回顧型文獻

Aconitum
Bradycardia
Hypotension
Herbal Medicine
Poisons

Cancer and mTOR inhibitors in kidney transplantation recipients

Kao, C. C., Liu, J. S., Chang, Y. K., Lin, M. H., Lin, Y. C., Chen, H. H., Chang, W. C., Hsu, C. C. & Wu, M. S., 一月 1 2018, 於 : PeerJ. 2018, 11, e5864.

研究成果: 雜誌貢獻文章

kidney transplant
Kidney Transplantation
neoplasms
Neoplasms
Hazards
6 引文 (Scopus)

Cerebellar α6-subunit-containing GABAA receptors: a novel therapeutic target for disrupted prepulse inhibition in neuropsychiatric disorders

Chiou, L-C., Lee, H-J., Ernst, M., Huang, W-J., Chou, J-F., Chen, H-L., Mouri, A., Chen, L-C., Treven, M., Mamiya, T., Fan, P-C., Knutson, D. E., Witzigmann, C., Cook, J., Sieghart, W. & Nabeshima, T., 2018, 於 : British Journal of Pharmacology. 175, 12, p. 2414-2427 14 p.

研究成果: 雜誌貢獻文章

GABA-A Receptors
Methamphetamine
Sensory Gating
Furosemide
Startle Reflex
3 引文 (Scopus)

Chemotherapy Immunophenoprofiles in Non-Small-Cell Lung Cancer by Personalized Membrane Proteomics

Putri, D. U., Feng, P. H., Hsu, Y. H., Lee, K. Y., Jiang, F. W., Kuo, L. W., Chen, Y. J. & Han, C. L., 一月 1 2018, (接受/付印) 於 : Proteomics - Clinical Applications.

研究成果: 雜誌貢獻文章

Pemetrexed
Chemotherapy
Non-Small Cell Lung Carcinoma
Proteomics
Cisplatin

Correction: 2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition (Org. Biomol. Chem. (2016) 14 (716-723))

Nepali, K., Kumar, S., Huang, H. L., Kuo, F. C., Lee, C. H., Kuo, C. C., Yeh, T. K., Li, Y. H., Chang, J. Y., Liou, J. P. & Lee, H. Y., 一月 1 2018, 於 : Organic and Biomolecular Chemistry. 16, 25, p. 4734 1 p.

研究成果: 雜誌貢獻文章

HSP90 Heat-Shock Proteins
Dione
Tubulin
Antineoplastic Agents
Emotions
Technology
Adenocarcinoma of lung
Myeloid-Derived Suppressor Cells
Singapore
Risk Management
Cost-Benefit Analysis
Randomized Controlled Trials
Costs and Cost Analysis

Design of diarylheptanoid derivatives as dual inhibitors against class IIa histone deacetylase and β-amyloid aggregation

Chen, L. C., Tseng, H. J., Liu, C. Y., Huang, Y. Y., Yen, C. C., Weng, J. R., Lu, Y. L., Hou, W. C., Lin, T. E., Pan, I. H., Huang, K. K., Huang, W. J. & Hsu, K. C., 七月 3 2018, 於 : Frontiers in Pharmacology. 9, JUL, 708.

研究成果: 雜誌貢獻文章

Diarylheptanoids
Histone Deacetylases
Amyloid
Alzheimer Disease
Pyrogallol
11 引文 (Scopus)
docetaxel
Lecithins
Drug Delivery Systems
Therapeutics
Neoplasms
3 引文 (Scopus)
pharmacokinetics
Hepatitis B virus
Pharmacokinetics
rats
Toll-Like Receptor 2
9 引文 (Scopus)
Calibration
antibody
Purification
purification
Blood Proteins
8 引文 (Scopus)

Discovery of aliphatic-chain hydroxamates containing indole derivatives with potent class I histone deacetylase inhibitory activities

Chao, S. W., Chen, L. C., Yu, C. C., Liu, C. Y., Lin, T. E., Guh, J. H., Wang, C. Y., Chen, C. Y., Hsu, K. C. & Huang, W. J., 一月 1 2018, 於 : European Journal of Medicinal Chemistry. 143, p. 792-805 14 p.

研究成果: 雜誌貢獻文章

Histone Deacetylases
Derivatives
Carbon
Molecular Docking Simulation
Cutaneous T-Cell Lymphoma
Pharmacokinetics
Metabolites
Hepatitis B
Rats
Urine
10 引文 (Scopus)

Dual inhibition of PIK3C3 and FGFR as a new therapeutic approach to treat bladder cancer

Chen, C. H., Changou, C. A., Hsieh, T. H., Lee, Y. C., Chu, C. Y., Hsu, K. C., Wang, H. C., Lin, Y. C., Lo, Y. N., Liu, Y. R., Liou, J. P. & Yen, Y., 三月 1 2018, 於 : Clinical Cancer Research. 24, 5, p. 1176-1189 14 p.

研究成果: 雜誌貢獻文章

Autophagy
Urinary Bladder Neoplasms
Cell Death
Therapeutics
Clustered Regularly Interspaced Short Palindromic Repeats
7 引文 (Scopus)
Atrial Fibrillation
Safety
Hemorrhage
Myocardial Infarction
Rivaroxaban
1 引文 (Scopus)
Hemoglobin
hemoglobin
metabolism
liver
Metabolism
1 引文 (Scopus)

Effects of metallic interlayers on the performance of nanocrystalline diamond metal-semiconductor-metal photodetectors

Liu, C-W., Lee, J-A., Albert Sun, Y-T., BenDao, M-K. & Lin, C-R., 十月 15 2018, 於 : Applied Surface Science. 455, p. 581-590 10 p.

研究成果: 雜誌貢獻文章

Diamond
Photodetectors
Diamonds
Diamond films
Metals
6 引文 (Scopus)
Apolipoproteins
Lysine
Immunoglobulin M
Alzheimer Disease
Peptides
1 引文 (Scopus)

Elevated levels of liver methylglyoxal and d-lactate in early-stage hepatitis in rats

Wang, W. C., Chou, C. K., Chuang, M. C., Li, Y. C. & Lee, J. A., 二月 2018, 於 : Biomedical Chromatography.

研究成果: 雜誌貢獻文章

Pyruvaldehyde
Liver
Hepatitis
Rats
Lactic Acid
4 引文 (Scopus)
Plasma (human)
3-Hydroxybutyric Acid
High performance liquid chromatography
Lactic Acid
Enantiomers
Gout
Health Care Costs
Cohort Studies
Population
Costs and Cost Analysis
23 引文 (Scopus)

Facile preparation of WO3/PEDOT: PSS composite for inkjet printed electrochromic window and its performance for heat shielding

Chang-Jian, C. W., Cho, E. C., Yen, S. C., Ho, B. C., Lee, K. C., Huang, J. H. & Hsiao, Y. S., 一月 1 2018, 於 : Dyes and Pigments. 148, p. 465-473 9 p.

研究成果: 雜誌貢獻文章

Heat shielding
Styrene
Electrochromic devices
Composite materials
Ink
1 引文 (Scopus)

Formation of organosilica nanoparticles with dual functional groups and simultaneous payload entrapment

Su, Y. L., Lin, C. Y., Chiu, S. J. & Hu, T. M., 五月 19 2018, 於 : Journal of Microencapsulation. 35, 4, p. 381-391 11 p.

研究成果: 雜誌貢獻文章

Rhodamines
entrapment
payloads
Nanoparticles
Functional groups
Patient Acceptance of Health Care
Warfarin
Secondary Prevention
Health Care Costs
Atrial Fibrillation
1 引文 (Scopus)

Healthcare costs and utilization of diabetes-related complications in Taiwan: A claims database analysis

Cheng, S-W., Wang, C-Y., Chen, J-H. & Ko, Y., 八月 2018, 於 : Medicine. 97, 31, p. e11602

研究成果: 雜誌貢獻文章

Insurance Claim Review
Diabetes Complications
Taiwan
Health Care Costs
Diabetes Mellitus
2 引文 (Scopus)
開啟存取
Oxidative Stress
Acetaminophen
Liver
Wounds and Injuries
Hep G2 Cells
2 引文 (Scopus)

Heteronemin induces anti-Proliferation in cholangiocarcinoma cells via inhibiting TGF-β pathway

Lin, H. Y., Tey, S. L., Ho, Y., Chin, Y. T., Wang, K., Whang-Peng, J., Shih, Y. J., Chen, Y. R., Yang, Y. N., Chen, Y. C., Liu, Y. C., Tang, H. Y. & Yang, Y. C. SH., 十二月 6 2018, 於 : Marine Drugs. 16, 12, 489.

研究成果: 雜誌貢獻文章

Cholangiocarcinoma
Transforming Growth Factors
Neoplasm Metastasis
Cell Adhesion
Cell Movement
2 引文 (Scopus)
Metoclopramide
Parkinsonian Disorders
Cohort Studies
Population
Health Insurance
3 引文 (Scopus)

Improvement of hyperglycemia in a murine model of insulin resistance and high glucose- and inflammasome-mediated IL-1β expressions in macrophages by silymarin

Lu, C. P., Huang, C. Y., Wang, S. H., Chiu, C. H., Li, L. H., Hua, K. F. & Wu, T. H., 六月 25 2018, 於 : Chemico-Biological Interactions. 290, p. 12-18 7 p.

研究成果: 雜誌貢獻文章

Inflammasomes
Silymarin
Macrophages
Interleukin-1
Hyperglycemia
1 引文 (Scopus)

Increased risk of a herpes zoster attack in patients receiving androgen deprivation therapy for prostate cancer

Wu, F. J., Kao, L. T., Sheu, S. Y., Lin, H. C. & Chung, S. D., 三月 1 2018, 於 : Andrologia. 50, 2, e12863.

研究成果: 雜誌貢獻文章

Herpes Zoster
Androgens
Prostatic Neoplasms
Therapeutics
Incidence
1 引文 (Scopus)

Increased risk of periodontitis among patients with Crohn’s disease: a population-based matched-cohort study

Chi, Y. C., Chen, J. L., Wang, L. H., Chang, K., Wu, C. L., Lin, S. Y., Keller, J. J. & Bai, C. H., 十月 1 2018, 於 : International Journal of Colorectal Disease. 33, 10, p. 1437-1444 8 p.

研究成果: 雜誌貢獻文章

Periodontitis
Crohn Disease
Cohort Studies
Population
Inflammatory Bowel Diseases
5 引文 (Scopus)

Inhibitory effect of Anoectochilus formosanus extract on hyperglycemia-related PD-L1 expression and cancer proliferation

Ho, Y., Chen, Y. F., Wang, L. H., Hsu, K. Y., Chin, Y. T., Yang, Y. C. S. H., Wang, S. H., Chen, Y. R., Shih, Y. J., Liu, L. F., Wang, K., Whang-Peng, J., Tang, H. Y., Lin, H. Y., Liu, H. L. & Lin, S. J., 八月 2 2018, 於 : Frontiers in Pharmacology. 9, AUG, 807.

研究成果: 雜誌貢獻文章

Obese Mice
Hyperglycemia
Blood Glucose
Metformin
Hypoglycemic Agents
1 引文 (Scopus)

Inhibitory effects of punicalagin from Punica granatum against type II collagenase-induced osteoarthritis

Lee, C. J., Chen, L. G., Liang, W. L., Hsieh, M. S. & Wang, C. C., 二月 1 2018, 於 : Journal of Functional Foods. 41, p. 216-222 7 p.

研究成果: 雜誌貢獻文章

Punicaceae
Punica granatum
collagenase
chondrocytes
osteoarthritis

Integrative genomic analysis for the functional roles of ITPKC in bone mineral density

Lu, H. F., Wong, H. S. C., Chen, B. K., Liao, H. T., Hsu, Y. W., Ikegawa, S., Cho, E. C., Hung, K. S. & Chang, W. C., 十一月 30 2018, 於 : Bioscience Reports. 38, 6, BSR20181481.

研究成果: 雜誌貢獻文章

Bone Density
Minerals
Bone
Genes
Osteoclasts
3 引文 (Scopus)

In vitro and in vivo anti-osteoarthritis effects of 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside from Polygonum multiflorum

Tsai, P. W., Lee, Y. H., Chen, L. G., Lee, C. J. & Wang, C. C., 一月 1 2018, 於 : Molecules. 23, 3, 571.

研究成果: 雜誌貢獻文章

prostaglandins
glucosides
nitric oxide
Dinoprostone
Osteoarthritis
2 引文 (Scopus)
rhodamine B
Energy Transfer
Micelles
cornea
micelles
1 引文 (Scopus)
Lecithins
Quercetin
Micelles
Therapeutic Uses
Doxorubicin
1 引文 (Scopus)
Medical Genetics
Chemokines
Cytokines
Tumor Microenvironment
Neoplasms
2 引文 (Scopus)
Warfarin
Carbon Dioxide
Carbon dioxide
Solubility
Flow rate
1 引文 (Scopus)

Mechanisms of butylidenephthalide for twitch facilitation in electrically stimulated mouse vas deferens

Shih, C. H., Chen, C. M. & Ko, W. C., 一月 1 2018, 於 : Pharmaceutical Biology. 56, 1, p. 378-387 10 p.

研究成果: 雜誌貢獻文章

開啟存取
Vas Deferens
Diltiazem
Verapamil
butylidenephthalide
Membranes
2 引文 (Scopus)

Melanogenesis inhibitors from the rhizoma of ligusticum sinense in B16-f10 melanoma cells in vitro and zebrafish in vivo

Cheng, M. C., Lee, T. H., Chu, Y. T., Syu, L. L., Hsu, S. J., Cheng, C. H., Wu, J. & Lee, C. K., 十二月 1 2018, 於 : International Journal of Molecular Sciences. 19, 12, 3994.

研究成果: 雜誌貢獻文章

Ligusticum
Experimental Melanomas
ferulic acid
Cosmetics
Zebrafish