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研究成果

(Journal of Food and Drug Analysis 18, 6, (380))

Cheng, Y. W. & Lou, H. Y., 六月 2011, 於 : Journal of Food and Drug Analysis. 19, 2, p. 243 1 p.

研究成果: 雜誌貢獻文章

(N-Hydroxycarbonylbenylamino)quinolines as Selective Histone Deacetylase 6 Inhibitors Suppress Growth of Multiple Myeloma in Vitro and in Vivo

Lee, H. Y., Nepali, K., Huang, F. I., Chang, C. Y., Lai, M. J., Li, Y. H., Huang, H. L., Yang, C. R. & Liou, J. P., 二月 8 2018, 於 : Journal of Medicinal Chemistry. 61, 3, p. 905-917 13 p.

研究成果: 雜誌貢獻文章

21 引文 斯高帕斯(Scopus)
5 引文 斯高帕斯(Scopus)

1-Aroylindoline-hydroxamic acids as anticancer agents, inhibitors of HSP90 and HDAC

Ojha, R., Huang, H. L., HuangFu, W. C., Wu, Y. W., Nepali, K., Lai, M. J., Su, C. J., Sung, T. Y., Chen, Y. L., Pan, S. L. & Liou, J. P., 四月 25 2018, 於 : European Journal of Medicinal Chemistry. 150, p. 667-677 11 p.

研究成果: 雜誌貢獻文章

14 引文 斯高帕斯(Scopus)

1-Arylsulfonyl-5-(N-hydroxyacrylamide)indolines Histone Deacetylase Inhibitors Are Potent Cytokine Release Suppressors

Lee, H. Y., Yang, C-R., Lai, M-J., Huang, H-L., Hsieh, Y-L., Liu, Y-M., Yeh, T-K., Li, Y-H., Mehndiratta, S., Teng, C-M. & Liou, J. P., 七月 2013, 於 : ChemBioChem. 14, 10, p. 1248-1254 7 p.

研究成果: 雜誌貢獻文章

14 引文 斯高帕斯(Scopus)
16 引文 斯高帕斯(Scopus)
7 引文 斯高帕斯(Scopus)

2,3,5,4′-tetrahydroxystilbene-2-O- β -glucoside isolated from Polygoni Multiflori ameliorates the development of periodontitis

Chin, Y. T., Hsieh, M. T., Lin, C. Y., Kuo, P. J., Yang, Y. C. S. H., Shih, Y. J., Lai, H. Y., Cheng, G. Y., Tang, H. Y., Lee, C. C., Lee, S. Y., Wang, C. C., Lin, H. Y., Fu, E., Whang-Peng, J. & Liu, L. F., 2016, 於 : Mediators of Inflammation. 2016, 6953459.

研究成果: 雜誌貢獻文章

15 引文 斯高帕斯(Scopus)

2-(Phenylsulfonyl)quinoline N-hydroxyacrylamides as potent anticancer agents inhibiting histone deacetylase

Lee, H. Y., Chang, C. Y., Su, C. J., Huang, H. L., Mehndiratta, S., Chao, Y. H., Hsu, C. M., Kumar, S., Sung, T. Y., Huang, Y. Z., Li, Y. H., Yang, C. R. & Liou, J. P., 十月 21 2016, 於 : European Journal of Medicinal Chemistry. 122, p. 92-101 10 p.

研究成果: 雜誌貢獻文章

7 引文 斯高帕斯(Scopus)

2001藥物實體外觀辨識手冊

Chien, S-C., 2001, 行政院衛生署.

研究成果: 报告类型書籍

檔案
7 下載 (Pure)

2002藥物實體外觀辨識手冊

Chien, S-C., 二月 2002, 行政院衛生署. 440 p.

研究成果: 报告类型書籍

2-Amino-3,4,5-Trimethoxybenzophenones as Potent Tubulin Polymerization Inhibitors

Chuang, H-Y., Chang, J-Y., Lai, M-J., Kuo, C-C., Lee, H. Y., Hsieh, H-P., Chen, Y-J., Chen, L-T., Pan, W-Y. & Liou, J. P., 三月 7 2011, 於 : ChemMedChem. 6, 3, p. 450-456 7 p.

研究成果: 雜誌貢獻文章

12 引文 斯高帕斯(Scopus)

2-Amino and 2′-aminocombretastatin derivatives as potent antimitotic agents

Chang, J. Y., Yang, M. F., Chang, C. Y., Chen, C. M., Kuo, C. C. & Liou, J. P., 十月 2006, 於 : Journal of Medicinal Chemistry. 49, 21, p. 6412-6415 4 p.

研究成果: 雜誌貢獻文章

44 引文 斯高帕斯(Scopus)

2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition

Nepali, K., Kumar, S., Huang, H. L., Kuo, F. C., Lee, C. H., Kuo, C. C., Yeh, T. K., Li, Y. H., Chang, J. Y., Liou, J. P. & Lee, H. Y., 2015, 於 : Organic and Biomolecular Chemistry. 14, 2, p. 716-723 8 p.

研究成果: 雜誌貢獻文章

6 引文 斯高帕斯(Scopus)

2-Methoxyestradiol attenuates phosphatidylinositol 3-kinase/Akt pathway-mediated metastasis of gastric cancer

Lin, H. L., Yang, M. H., Wu, C. W., Chen, P. M., Yang, Y. P., Chu, Y. R., Kao, C. L., Ku, H. H., Lo, J. F., Liou, J. P., Chi, C. W. & Chiou, S. H., 十二月 1 2007, 於 : International Journal of Cancer. 121, 11, p. 2547-2555 9 p.

研究成果: 雜誌貢獻文章

37 引文 斯高帕斯(Scopus)

3-Aroylindoles display antitumor activity in vitro and in vivo: Effects of N1-substituents on biological activity

Lee, H-Y., Lee, J. F., Kumar, S., Wu, Y. W., HuangFu, W-C., Lai, M-J., Li, Y-H., Huang, H. L., Kuo, F. C., Hsiao, C. J., Cheng, C. C., Yang, C. R. & Liou, J-P., 一月 5 2017, 於 : European Journal of Medicinal Chemistry. 125, p. 1268-1278 11 p.

研究成果: 雜誌貢獻文章

19 引文 斯高帕斯(Scopus)

4- And 5-aroylindoles as novel classes of potent antitubulin agents

Liou, J. P., Wu, C. Y., Hsieh, H. P., Chang, C. Y., Chen, C. M., Kuo, C. C. & Chang, J. Y., 九月 6 2007, 於 : Journal of Medicinal Chemistry. 50, 18, p. 4548-4552 5 p.

研究成果: 雜誌貢獻文章

57 引文 斯高帕斯(Scopus)

4-Indolyl-N-hydroxyphenylacrylamides as potent HDAC class I and IIB inhibitors in vitro and in vivo

Mehndiratta, S., Wang, R. S., Huang, H. L., Su, C. J., Hsu, C. M., Wu, Y. W., Pan, S. L. & Liou, J. P., 七月 7 2017, 於 : European Journal of Medicinal Chemistry. 134, p. 13-23 11 p.

研究成果: 雜誌貢獻文章

11 引文 斯高帕斯(Scopus)
8 引文 斯高帕斯(Scopus)
6 引文 斯高帕斯(Scopus)

5-Amino-2-Aroylquinolines as highly potent tubulin polymerization inhibitors

Nien, C. Y., Chen, Y. C., Kuo, C. C., Hsieh, H. P., Chang, C. Y., Wu, J. S., Wu, S. Y., Liou, J. P. & Chang, J. Y., 三月 11 2010, 於 : Journal of Medicinal Chemistry. 53, 5, p. 2309-2313 5 p.

研究成果: 雜誌貢獻文章

65 引文 斯高帕斯(Scopus)

5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors. Part 2. The impact of bridging groups at position C-2

Lee, H. Y., Chang, J. Y., Nien, C. Y., Kuo, C. C., Shih, K. H., Wu, C. H., Chang, C. Y., Lai, W. Y. & Liou, J. P., 十二月 22 2011, 於 : Journal of Medicinal Chemistry. 54, 24, p. 8517-8525 9 p.

研究成果: 雜誌貢獻文章

42 引文 斯高帕斯(Scopus)

5-Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer's Disease Phenotypes

Lee, H. Y., Fan, S. J., Huang, F. I., Chao, H. Y., Hsu, K. C., Lin, T. E., Yeh, T. K., Lai, M. J., Li, Y. H., Huang, H. L., Yang, C. R. & Liou, J. P., 一月 29 2018, (接受/付印) 於 : Journal of Medicinal Chemistry.

研究成果: 雜誌貢獻文章

15 引文 斯高帕斯(Scopus)

6-Acyl-4-aryl/alkyl-5,7-dihydroxycoumarins as anti-inflammatory agents

Lin, C. M., Huang, S. T., Lee, F. W., Kuo, H. S. & Lin, M. H., 七月 1 2006, 於 : Bioorganic and Medicinal Chemistry. 14, 13, p. 4402-4409 8 p.

研究成果: 雜誌貢獻文章

62 引文 斯高帕斯(Scopus)

7-Aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents

Chang, J. Y., Hsieh, H. P., Chang, C. Y., Hsu, K. S., Chiang, Y. F., Chen, C. M., Kuo, C. C. & Liou, J. P., 十一月 16 2006, 於 : Journal of Medicinal Chemistry. 49, 23, p. 6656-6659 4 p.

研究成果: 雜誌貢獻文章

61 引文 斯高帕斯(Scopus)
16 引文 斯高帕斯(Scopus)

A 5' AMP-Activated Protein Kinase Enzyme Activator, Compound 59, Induces Autophagy and Apoptosis in Human Oral Squamous Cell Carcinoma

Weng, J. R., Dokla, E. M. E., Bai, L. Y., Chen, C. S., Chiu, S. J. & Shieh, T. M., 一月 1 2018, (接受/付印) 於 : Basic and Clinical Pharmacology and Toxicology.

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)

Acacetin inhibits glutamate release and prevents kainic acid-induced neurotoxicity in rats

Lin, T. Y., Huang, W. J., Wu, C. C., Lu, C. W. & Wang, S. J., 二月 10 2014, 於 : PLoS One. 9, 2, e88644.

研究成果: 雜誌貢獻文章

33 引文 斯高帕斯(Scopus)

Accumulation of methylglyoxal and d-lactate in Pb-induced nephrotoxicity in rats

Huang, Y. S., Li, Y. C., Tsai, P. Y., Lin, C. E., Chen, C. M., Chen, S-M. & Lee, J-A., 五月 2017, 於 : Biomedical Chromatography.

研究成果: 雜誌貢獻文章

9 引文 斯高帕斯(Scopus)

A Chinese herbal medicine, Jia-Wei-Xiao-Yao-San, prevents dimethylnitrosamine-induced hepatic fibrosis in rats

Chien, S-C., Chang, W. C., Lin, P. H., Chang, W. P., Hsu, S. C., Chang, J. C., Wu, Y. C., Pei, J. K. & Lin, C. H., 2014, 於 : Scientific World Journal. 2014, 217525.

研究成果: 雜誌貢獻文章

24 引文 斯高帕斯(Scopus)

A combination of pharmacophore and in silico approaches for identification of potential transthyretin amyloidosis inhibitors

Zhou, Z. L., Liu, H. L., Wu, J. W., Tsao, C. W., Chen, W. H., Liu, K. T. & Ho, Y., 一月 2014, 於 : Letters in Drug Design and Discovery. 11, 3, p. 339-348 10 p.

研究成果: 雜誌貢獻文章

A concise synthesis of denbinobin

Wang, Y. C., Lin, C-H., Chen, C. M. & Liou, J. P., 十一月 21 2005, 於 : Tetrahedron Letters. 46, 47, p. 8103-8104 2 p.

研究成果: 雜誌貢獻文章

11 引文 斯高帕斯(Scopus)

Aconitamide, a novel alkaloid from the roots of Aconitum carmichaeli

Li, Z-H., Chen, Y. C., Lee, C. K., Chang, H. S., Kuo, C. C., Chao, C. Y., Lin, J. J., Lo, L. C. & Kuo, Y. H., 2013, 於 : Natural Product Communications. 8, 6, p. 827-828 2 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)

A cost-effectiveness analysis of trastuzumab-containing treatment sequences for HER-2 positive metastatic breast cancer patients in Taiwan

Diaby, V., Alqhtani, H., van Boemmel-Wegmann, S., Wang, C. Y., Ali, A. A., Balkrishnan, R., Ko, Y., Palacio, S. & de Lima Lopes, G., 二月 1 2020, 於 : Breast. 49, p. 141-148 8 p.

研究成果: 雜誌貢獻文章

開啟存取
1 引文 斯高帕斯(Scopus)

Activation and up-regulation of nitric oxide synthase in human umbilical vein endothelial cells by polycyclic aromatic hydrocarbons

Li, C. H., Lee, C. C., Cheng, Y. W., Juang, H. A. & Kang, J. J., 七月 15 2004, 於 : Toxicology Letters. 151, 2, p. 367-374 8 p.

研究成果: 雜誌貢獻文章

11 引文 斯高帕斯(Scopus)

Acute hypoxia enhances proteins' S-nitrosylation in endothelial cells

Chen, S-C., Huang, B., Liu, Y. C., Shyu, K-G., Lin, P. Y. & Wang, D. L., 十二月 26 2008, 於 : Biochemical and Biophysical Research Communications. 377, 4, p. 1274-1278 5 p.

研究成果: 雜誌貢獻文章

28 引文 斯高帕斯(Scopus)

Acute nephrotoxicity of aristolochic acids in mice

Sato, N., Takahashi, D., Chen, S. M., Tsuchiya, R., Mukoyama, T., Yamagata, S. I., Ogawa, M., Yoshida, M., Kondo, S., Satoh, N. & Ueda, S., 二月 2004, 於 : Journal of Pharmacy and Pharmacology. 56, 2, p. 221-229 9 p.

研究成果: 雜誌貢獻文章

92 引文 斯高帕斯(Scopus)

Adjunctive traditional Chinese medicine therapy improves survival in patients with advanced breast cancer: A population-based study

Lee, Y-W., Chen, T-L., Shih, Y. R. V., Tsai, C. L., Chang, C-C., Liang, H-H., Tseng, S-H., Chien, S-C. & Wang, C-C., 五月 1 2014, 於 : Cancer. 120, 9, p. 1338-1344 7 p.

研究成果: 雜誌貢獻文章

62 引文 斯高帕斯(Scopus)

A dose-dependent pharmacokinetic study of levodopa by intramuscular administration in rabbits

Wang, L. H., Hsu, K. Y., Hsu, F-L. & Lin, S. J., 十月 2008, 於 : Journal of Food and Drug Analysis. 16, 5, p. 21-27 7 p.

研究成果: 雜誌貢獻文章

1 引文 斯高帕斯(Scopus)

A dose-dependent pharmacokinetic study on caffeic acid in rabbits after intravenous administration

Uang, Y. S. & Hsu, K. Y., 1997, 於 : Biopharmaceutics and Drug Disposition. 18, 8, p. 727-736 10 p.

研究成果: 雜誌貢獻文章

11 引文 斯高帕斯(Scopus)
3 引文 斯高帕斯(Scopus)
1 引文 斯高帕斯(Scopus)

A histone deacetylase inhibitor enhances expression of genes inhibiting Wnt pathway and augments activity of DNA demethylation reagent against nonsmall-cell lung cancer

Shieh, J. M., Tang, Y. A., Hu, F. H., Huang, W. J., Wang, Y. J., Jen, J., Liao, S. Y., Lu, Y. H., Yeh, Y. L., Wang, T. W., Lin, P. & Wang, Y. C., 五月 15 2017, 於 : International Journal of Cancer. 140, 10, p. 2375-2386 12 p.

研究成果: 雜誌貢獻文章

12 引文 斯高帕斯(Scopus)

A histone deacetylase inhibitor YCW1 with antitumor and antimetastasis properties enhances cisplatin activity against non-small cell lung cancer in preclinical studies

Huang, W. J., Tang, Y. A., Chen, M. Y., Wang, Y. J., Hu, F. H., Wang, T. W., Chao, S. W., Chiu, H. W., Yeh, Y. L., Chang, H. Y., Juan, H. F., Lin, P. & Wang, Y. C., 四月 28 2014, 於 : Cancer Letters. 346, 1, p. 84-93 10 p.

研究成果: 雜誌貢獻文章

18 引文 斯高帕斯(Scopus)

Allopurinol, benzbromarone and risk of coronary heart disease in gout patients: A population-based study

Lin, H. C., Daimon, M., Wang, C. H., Ho, Y., Uang, Y. S., Chiang, S. J. & Wang, L. H., 四月 15 2017, 於 : International Journal of Cardiology. 233, p. 85-90 6 p.

研究成果: 雜誌貢獻文章

12 引文 斯高帕斯(Scopus)
9 引文 斯高帕斯(Scopus)

Alphitolic acid, an anti-inflammatory triterpene, induces apoptosis and autophagy in oral squamous cell carcinoma cells, in part, through a p53-dependent pathway

Bai, L. Y., Chiu, C. F., Chiu, S. J., Chen, Y. W., Hu, J. L., Wu, C. Y. & Weng, J. R., 十月 1 2015, 於 : Journal of Functional Foods. 18, p. 368-378 11 p., 1245.

研究成果: 雜誌貢獻文章

11 引文 斯高帕斯(Scopus)

Alteration of mesenchymal stem cells polarity by laminar shear stimulation promoting β-catenin nuclear localization

Chen, W-T., Hsu, W-T., Yen, M-H., Changou, C. A., Han, C-L., Chen, Y-J., Cheng, J-Y., Chang, T-H., Lee, O. K-S. & Ho, J. H-C., 一月 1 2019, 於 : Biomaterials. 190-191, p. 1-10 10 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)

Alterations in histone deacetylase 8 lead to cell migration and poor prognosis in breast cancer

Hsieh, C. L., Ma, H. P., Su, C-M., Chang, Y. J., Hung, W. Y., Ho, Y. S., Huang, W. J. & Lin, R. K., 四月 15 2016, 於 : Life Sciences. 151, p. 7-14 8 p.

研究成果: 雜誌貢獻文章

16 引文 斯高帕斯(Scopus)

Alternative Therapies as a Substitute for Costly Prescription Medications: Results from the 2011 National Health Interview Survey

Wang, C. C., Kennedy, J. & Wu, C. H., 六月 3 2015, 於 : Clinical Therapeutics. 37, 5, p. 1022-1030 9 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)