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研究成果

2020

A cost-effectiveness analysis of trastuzumab-containing treatment sequences for HER-2 positive metastatic breast cancer patients in Taiwan

Diaby, V., Alqhtani, H., van Boemmel-Wegmann, S., Wang, C. Y., Ali, A. A., Balkrishnan, R., Ko, Y., Palacio, S. & de Lima Lopes, G., 二月 1 2020, 於 : Breast. 49, p. 141-148 8 p.

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An assessment of the psychometric properties of the Chinese version of the Gout Impact Scale

Pao, C. H. & Ko, Y., 一月 2 2020, 於 : Current Medical Research and Opinion. 36, 1, p. 17-21 5 p.

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1 引文 斯高帕斯(Scopus)

Bioassay-guided isolation and HPLC quantification of antiproliferative metabolites from Stahlianthus thorelii

Nguyen, N. L., Vo, T. H., Lin, Y. C., Liaw, C. C., Lin, Z. H., Chen, M. C. & Kuo, Y. H., 一月 28 2020, 於 : Molecules. 25, 3, 551.

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Comparison of the predictive outcomes for anti-tuberculosis drug-induced hepatotoxicity by different machine learning techniques

Lai, N. H., Shen, W. C., Lee, C. N., Chang, J. C., Hsu, M. C., Kuo, L. N., Yu, M. C. & Chen, H. Y., 五月 2020, 於 : Computer Methods and Programs in Biomedicine. 188, 105307.

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Design, synthesis, and biological evaluation of heterotetracyclic quinolinone derivatives as anticancer agents targeting topoisomerases

Lee, J. F., Chang, T. Y., Liu, Z. F., Lee, N. Z., Yeh, Y. H., Chen, Y. S., Chen, T. C., Chou, H. S., Li, T. K., Lee, S. B. & Lin, M. H., 三月 15 2020, 於 : European Journal of Medicinal Chemistry. 190, 112074.

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Design and synthesis of 3-benzylaminocoumarin-7-O-sulfamate derivatives as steroid sulfatase inhibitors

Hng, Y., Lin, M. H., Lin, T. S., Liu, I. C., Lin, I. C., Lu, Y. L., Chang, C. N., Chiu, P. F., Tsai, K. C., Chen, M. J. & Liang, P. H., 三月 2020, 於 : Bioorganic Chemistry. 96, 103618.

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Dramatically enhanced mechanical properties of diamond-like carbon films on polymer substrate for flexible display devices via argon plasma pretreatment

Lee, J. A., Lin, C. R., Pan, P. C., Liu, C. W. & Sun, A. Y. T., 一月 15 2020, 於 : Chemical Physics. 529, 110551.

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Human Breathomics Database

Kuo, T. C., Tan, C. E., Wang, S. Y., Lin, O. A., Su, B. H., Hsu, M. T., Lin, J., Cheng, Y. Y., Chen, C. S., Yang, Y. C., Chen, K. H., Lin, S. W., Ho, C. C., Kuo, C. H. & Tseng, Y. J., 一月 1 2020, 於 : Database : the journal of biological databases and curation. 2020

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Intercalating pyrene with polypeptide as a novel self-assembly nano-carrier for colon cancer suppression in vitro and in vivo

Lo, P. Y., Lee, G. Y., Zheng, J. H., Huang, J. H., Cho, E. C. & Lee, K. C., 四月 1 2020, 於 : Materials Science and Engineering C. 109, 110593.

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N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-γ induced PD-L1 expression

Mehndiratta, S., Lin, M. H., Wu, Y. W., Chen, C. H., Wu, T. Y., Chuang, K. H., Chao, M. W., Chen, Y. Y., Pan, S. L., Chen, M. C. & Liou, J. P., 一月 1 2020, 於 : European Journal of Medicinal Chemistry. 185, p. 111725 111725.

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1 引文 斯高帕斯(Scopus)

NDAT suppresses pro-inflammatory gene expression to enhance resveratrol-induced anti-proliferation in oral cancer cells

Ho, Y., Wu, C. Y., Chin, Y. T., Li, Z. L., Pan, Y. S., Huang, T. Y., Su, P. Y., Lee, S. Y., Crawford, D. R., Su, K. W., Chiu, H. C., Shih, Y. J., Changou, C. A., Yang, Y. C. S. H., Whang-Peng, J., Chen, Y. R., Lin, H. Y., Mousa, S. A., Davis, P. J. & Wang, K., 二月 1 2020, 於 : Food and Chemical Toxicology. 136, p. 111092 111092.

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1 引文 斯高帕斯(Scopus)

Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment

Kaur, N., Fang, Y. C., Lee, H. Y., Singh, A., Nepali, K., Lin, M. H., Yeh, T. K., Lai, M. J., Chan, L., Tu, Y. K., Banerjee, S., Hu, C. J. & Liou, J. P., 二月 1 2020, 於 : European Journal of Medicinal Chemistry. 187, 111915.

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Quantifying the level of difficulty to treat major depressive disorder with antidepressants: Treatment resistance to antidepressants evaluation scale

Liu, T. Y., Kuo, P. H., Lu, M. L., Huang, M. C., Chen, C. H., Wu, T. H., Wang, S., Mao, W. C. & Chen, H. C., 一月 1 2020, 於 : PLoS ONE. 15, 1, p. e0227614 e0227614.

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Steering the antitumor drug discovery campaign towards structurally diverse indolines

Thakur, A., Singh, A., Kaur, N., Ojha, R. & Nepali, K., 一月 2020, 於 : Bioorganic Chemistry. 94, 103436.

研究成果: 雜誌貢獻回顧型文獻

1 引文 斯高帕斯(Scopus)

Synthesis and biological evaluation of 2-quinolineacrylamides

Wang, S. W., Lin, M. H., Hsu, F. C., Chen, M. C., Liou, J. P., Liu, Y. T., Chen, S. S. & Lee, H. Y., 二月 1 2020, 於 : Bioorganic and Medicinal Chemistry. 28, 3, p. 115250 115250.

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2019
5 引文 斯高帕斯(Scopus)

Alteration of mesenchymal stem cells polarity by laminar shear stimulation promoting β-catenin nuclear localization

Chen, W-T., Hsu, W-T., Yen, M-H., Changou, C. A., Han, C-L., Chen, Y-J., Cheng, J-Y., Chang, T-H., Lee, O. K-S. & Ho, J. H-C., 一月 1 2019, 於 : Biomaterials. 190-191, p. 1-10 10 p.

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1 引文 斯高帕斯(Scopus)
1 引文 斯高帕斯(Scopus)

A novel preventive mechanism of gentamicin-induced nephrotoxicity by atorvastatin

Lee, M. C., Cheng, K. J., Chen, S. M., Li, Y. C., Imai, K., Lee, C. M. & Lee, J. A., 十一月 1 2019, 於 : Biomedical Chromatography. 33, 11, p. e4639 e4639.

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Anti-metastatic activity of MPT0G211, a novel HDAC6 inhibitor, in human breast cancer cells in vitro and in vivo

Hsieh, Y. L., Tu, H. J., Pan, S. L., Liou, J. P. & Yang, C. R., 六月 1 2019, 於 : Biochimica et Biophysica Acta - Molecular Cell Research. 1866, 6, p. 992-1003 12 p.

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5 引文 斯高帕斯(Scopus)

Applications of cyclic peptide nanotubes (cPNTs)

Hsieh, W. H. & Liaw, J., 一月 2019, (接受/付印) 於 : Journal of Food and Drug Analysis. 27, 1

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4 引文 斯高帕斯(Scopus)

Association between Anticholinergic Medication Use and Risk of Dementia among Patients with Parkinson's Disease

Sheu, J. J., Tsai, M. T., Erickson, S. R. & Wu, C. H., 一月 1 2019, 於 : Pharmacotherapy. 39, 8, p. 798-808 11 p.

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2 引文 斯高帕斯(Scopus)

Association of endothelin genetic variants and hospitalized infection complications in end-stage renal disease (ESRD) patients

Kao, C. C., Cheng, S. Y., Wang, Y. J., Chien, S. C., Hsu, Y. W., Wu, M. Y., Lu, H. F., Nam, S., Sun, T., Wu, M. S. & Chang, W. C., 六月 5 2019, 於 : BMC Nephrology. 20, 1, p. 203 203.

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3 引文 斯高帕斯(Scopus)

Cancers in Taiwan: Practical insight from epidemiology, treatments, biomarkers, and cost

Kuo, C. N., Liao, Y. M., Kuo, L. N., Tsai, H. J., Chang, W. C. & Yen, Y., 一月 1 2019, (接受/付印) 於 : Journal of the Formosan Medical Association.

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1 引文 斯高帕斯(Scopus)

Carboxylated carbon nanomaterials in cell cycle and apoptotic cell death regulation

Lee, K. C., Lo, P. Y., Lee, G. Y., Zheng, J. H. & Cho, E. C., 四月 20 2019, 於 : Journal of Biotechnology. 296, p. 14-21 8 p.

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5 引文 斯高帕斯(Scopus)

Characterization of T-Cell Receptor Repertoire in Patients with Rheumatoid Arthritis Receiving Biologic Therapies

Chang, C. M., Hsu, Y. W., Wong, H. S. C., Wei, J. C. C., Liu, X., Liao, H. T. & Chang, W. C., 一月 1 2019, 於 : Disease Markers. 2019, 1 p.

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1 引文 斯高帕斯(Scopus)

Characterizing tyrosinase modulators from the roots of angelica keiskei using tyrosinase inhibition assay and UPLC-MS/MS as the combinatorial novel approach

Lee, J. H., Mei, H. C., Kuo, I. C., Lee, T. H., Chen, Y. H. & Lee, C. K., 九月 10 2019, 於 : Molecules. 24, 18, 3297.

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3 引文 斯高帕斯(Scopus)

Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status

Chao, M. W., Chang, L. H., Tu, H. J., Chang, C. D., Lai, M. J., Chen, Y. Y., Liou, J. P., Teng, C. M. & Pan, S. L., 五月 29 2019, 於 : Clinical Epigenetics. 11, 1, 85.

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3 引文 斯高帕斯(Scopus)

Constructing a bilingual website with validated database for Herb and Western medicine interactions using Ginseng, Ginkgo and Dong Quai as examples

Wu, C. S., Chen, Y. H., Chen, C. L., Chien, S. K., Syifa, N., Hung, Y. C., Cheng, K. J., Hu, S. C., Lo, P. T., Lin, S. Y. & Wu, T. H., 十一月 27 2019, 於 : BMC Complementary and Alternative Medicine. 19, 1, 335.

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Correction: Artocarpin, an isoprenyl flavonoid, induces p53-dependent or independent apoptosis via ROS-mediated MAPKs and Akt activation in non-small cell lung cancer cells

Tsai, M. H., Liu, J. F., Chiang, Y. C., Hu, S. C. S., Hsu, L. F., Lin, Y. C., Lin, Z. C., Lee, H. C., Chen, M. C., Huang, C. L. & Lee, C. W., 五月 21 2019, 於 : Oncotarget. 10, 36, p. 3430 1 p.

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Costs and Length of Stay of Hospitalizations due to Diabetes-Related Complications

Cheng, S. W., Wang, C. Y. & Ko, Y., 一月 1 2019, 於 : Journal of Diabetes Research. 2019, 2363292.

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Determination of synthetic cathinone α-pyrrolidinovalero-phenone and its metabolite in urine using solid-phase extraction and gas chromatography–mass spectrometry

Cheng, K. W., Hsieh, C. M., Chen, H. W., Chi, P. C., Yang, D. P., Chan, S. H., Chen, J. Y., Hwa, H. L., Fang, C. C., Weng, T. I. & Chen, P. S., 一月 1 2019, (接受/付印) 於 : Rapid Communications in Mass Spectrometry. e8579.

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Development of Decellularized Cornea by Organic Acid Treatment for Corneal Regeneration

Lin, H. J., Wang, T. J., Li, T. W., Chang, Y. Y., Sheu, M. T., Huang, Y. Y. & Liu, D. Z., 四月 1 2019, 於 : Tissue Engineering - Part A. 25, 7-8, p. 652-662 11 p.

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3 引文 斯高帕斯(Scopus)

Discovery of Novel Irreversible HER2 Inhibitors for Breast Cancer Treatment

Tang, J. Y., Ho, Y., Chang, C. Y. & Liu, H. L., 四月 2019, 於 : Journal of Biomedical Science and Engineering.

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Divaricoside Exerts Antitumor Effects, in Part, by Modulating Mcl-1 in Human Oral Squamous Cell Carcinoma Cells

Weng, J. R., Bai, L. Y., Chiu, S. J., Chiu, C. F., Lin, W. Y., Hu, J. L. & Shieh, T. M., 一月 1 2019, 於 : Computational and Structural Biotechnology Journal. 17, p. 151-159 9 p.

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2 引文 斯高帕斯(Scopus)

Does long-term use of antidiabetic drugs changes cancer risk?

Liu, Y. C., Nguyen, P. A., Humayun, A., Chien, S. C., Yang, H. C., Asdary, R. N., Syed-Abdul, S., Hsu, M. H., Moldovan, M., Yen, Y., Li, Y. C., Jian, W. S. & Iqbal, U., 十月 1 2019, 於 : Medicine (United States). 98, 40, p. e17461 e17461.

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1 引文 斯高帕斯(Scopus)

Down-regulation of aryl hydrocarbon receptor intensifies carcinogen-induced retinal lesion via SOCS3-STAT3 signaling

Tsai, C. H., Lee, Y., Li, C. H., Cheng, Y. W. & Kang, J. J., 一月 1 2019, (接受/付印) 於 : Cell Biology and Toxicology.

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