醫學生物科技博士學位學程

2020

Alterations of specific lymphocytic subsets with aging and age-related metabolic and cardiovascular diseases

Chen, Y. J., Liao, Y. J., Tram, V. T. N., Lin, C. H., Liao, K. C. & Liu, C. L., 10月 2020, 於: Life. 10, 10, p. 1-16 16 p., 246.

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3 引文斯高帕斯（Scopus）

Altered expressions and splicing profiles of Acin1 transcripts differentially modulate brown adipogenesis through an alternative splicing mechanism

Lin, Y. C., Lu, Y. H., Lee, Y. C., Hung, C. S. & Lin, J. C., 9月 1 2020, 於: Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1863, 9, p. 194601 194601.

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2 引文斯高帕斯（Scopus）

Alternatively spliced MBNL1 isoforms exhibit differential influence on enhancing brown adipogenesis

Hung, C. S. & Lin, J. C., 1月 2020, 於: Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1863, 1, p. 194437 194437.

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5 引文斯高帕斯（Scopus）

An Innovative Scoring System for Predicting Major Adverse Cardiac Events in Patients with Chest Pain Based on Machine Learning

Wu, C. C., Hsu, W. D., Wang, Y. C., Kung, W. M., Tzeng, I. S., Huang, C. W., Huang, C. Y. & Li, Y. C., 2020, 於: IEEE Access. 8, p. 124076-124083 8 p., 9123343.

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3 引文斯高帕斯（Scopus）

An integrated genomic strategy to identify CHRNB4 as a diagnostic/prognostic biomarker for targeted therapy in head and neck cancer

Chuang, Y. H., Lee, C. H., Lin, C. Y., Liu, C. L., Huang, S. H., Lee, J. Y., Chiu, Y. Y., Lee, J. C. & Yang, J. M., 5月 2020, 於: Cancers. 12, 5, 1324.

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1 引文斯高帕斯（Scopus）

Antifibrotic Effects of a Barbituric Acid Derivative on Liver Fibrosis by Blocking the NF-κB Signaling Pathway in Hepatic Stellate Cells

Wang, Y. H., Suk, F. M., Liu, C. L., Chen, T. L., Twu, Y. C., Hsu, M. H. & Liao, Y. J., 3月 31 2020, 於: Frontiers in Pharmacology. 11, 388.

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10 引文斯高帕斯（Scopus）

Application of a Common Data Model (CDM) to rank the paediatric user and prescription prevalence of 15 different drug classes in South Korea, Hong Kong, Taiwan, Japan and Australia: An observational, descriptive study

Brauer, R., Wong, I. C. K., Man, K. K. C., Pratt, N. L., Park, R. W., Cho, S. Y., Li, Y. C., Iqbal, U., Nguyen, P. A. A. & Schuemie, M., 1月 13 2020, 於: BMJ Open. 10, 1, p. e032426 032426.

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3 引文斯高帕斯（Scopus）

Arsenic exposure and methylation efficiency in relation to oxidative stress in semiconductor workers

Pan, C. H., Lin, C. Y., Lai, C. H. & Jeng, H. A., 5月 1 2020, 於: ATMOSPHERE. 11, 5, 464.

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3 引文斯高帕斯（Scopus）

Artificial Intelligence in Ophthalmology: A Meta-Analysis of Deep Learning Models for Retinal Vessels Segmentation

Islam, M. M., Poly, T. N., Walther, B. A., Yang, H. C. & Li, Y-C. J., 4月 3 2020, 於: Journal of Clinical Medicine. 9, 4

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24 引文斯高帕斯（Scopus）

Artificial neural network-based analysis of the safetand efficacy of thrombolysis for ischemic stroke in older adults in Taiwan

Chung, C. C., Chen, Y. C., Hong, C. T., Chi, N. F., Hu, C. J., Hu, H. H., Chan, L. & Chiu, H. W., 6月 2020, 於: Neurology Asia. 25, 2, p. 109-117 9 p.

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1 引文斯高帕斯（Scopus）

Artificial neural network based prediction of postthrombolysis intracerebral hemorrhage and death

Chung, C. C., Chan, L., Bamodu, O. A., Hong, C. T. & Chiu, H. W., 12月 2020, 於: Scientific Reports. 10, 1, 20501.

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12 引文斯高帕斯（Scopus）

Association between benzodiazepines use and risk of hip fracture in the elderly people: A meta-analysis of observational studies

Poly, T. N., Islam, M. M., Yang, H. C. & Li, Y. C., 3月 2020, 於: Joint Bone Spine. 87, 3, p. 241-249

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11 引文斯高帕斯（Scopus）

Association between Use of Statin and Risk of Dementia: A Meta-Analysis of Observational Studies

Poly, T. N., Islam, M. M., Walther, B. A., Yang, H. C., Wu, C. C., Lin, M. C. & Li, Y. C., 5月 1 2020, 於: Neuroepidemiology. 54, 3, p. 214-226 13 p.

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39 引文斯高帕斯（Scopus）

Association entre prise de benzodiazépines et risque de fracture de la hanche chez la personne âgée: méta-analyse d’études observationnelles

Poly, T. N., Islam, M. M., Yang, H. C. & Li, Y. C., 5月 2020, 於: Revue du Rhumatisme (Edition Francaise). 87, 3, p. 210-220 11 p.

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Astragalus membranaceus-Derived Anti-Programmed Death-1 Monoclonal Antibodies with Immunomodulatory Therapeutic Effects against Tumors

Chang, F. L., Tsai, K. C., Lin, T. Y., Yang, T. W., Lo, Y. N., Chen, W. C., Chang, J. H., Lu, M. K., Chiou, C. T., Chen, P. H., Yen, Y., Pan, S. L. & Lee, Y. C., 1月 1 2020, 於: BioMed Research International. 2020, 3415471.

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9 引文斯高帕斯（Scopus）

Characteristics of CD133-Sustained Chemoresistant Cancer Stem-Like Cells in Human Ovarian Carcinoma

Liu, C. L., Chen, Y. J., Fan, M. H., Liao, Y. J. & Mao, T. L., 9月 2 2020, 於: International journal of molecular sciences. 21, 18, p. 1-17 17 p., 6467.

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8 引文斯高帕斯（Scopus）

Characterization of fecal microbiota with clinical specimen using long-read and short-read sequencing platform

Wei, P. L., Hung, C. S., Kao, Y. W., Lin, Y. C., Lee, C. Y., Chang, T. H., Shia, B. C. & Lin, J. C., 10月 1 2020, 於: International journal of molecular sciences. 21, 19, p. 1-12 12 p., 7110.

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5 引文斯高帕斯（Scopus）

Classification of changes in the fecal microbiota associated with colonic adenomatous polyps using a long-read sequencing platform

Wei, P. L., Hung, C. S., Kao, Y. W., Lin, Y. C., Lee, C. Y., Chang, T. H., Shia, B. C. & Lin, J. C., 11月 2020, 於: Genes. 11, 11, p. 1-14 14 p., 1374.

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5 引文斯高帕斯（Scopus）

Clinical manifestations and treatments of Protobothrops mucrosquamatus bite and associated factors for wound necrosis and subsequent debridement and finger or toe amputation surgery

Mao, Y. C., Liu, P. Y., Chiang, L. C., Lee, C. H., Lai, C. S., Lai, K. L., Lin, W. L., Su, H. Y., Ho, C. H., Doan, U. V., Maharani, T., Yang, Y. Y. & Yang, C. C., 2020, 於: Clinical Toxicology. p. 1-10 10 p.

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10 引文斯高帕斯（Scopus）

Computational analysis for identification of the extracellular matrix molecules involved in endometrial cancer progression

Yadav, V. K., Lee, T. Y., Hsu, J. B. K., Huang, H. D., Yang, W. C. V. & Chang, T. H., 4月 1 2020, 於: PLoS ONE. 15, 4, p. e0231594 e0231594.

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14 引文斯高帕斯（Scopus）

Computer-aided bacillus detection in whole-slide pathological images using a deep convolutional neural network

Lo, C. M., Wu, Y. H., (Jack) Li, Y. C. & Lee, C. C., 6月 1 2020, 於: Applied Sciences (Switzerland). 10, 12, p. 1-12 12 p., 4059.

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6 引文斯高帕斯（Scopus）

COVID-19 preventive measures showing an unintended decline in infectious diseases in Taiwan

Galvin, C. J., Li, Y. C., Malwade, S. & Syed-Abdul, S., 9月 1 2020, 於: International Journal of Infectious Diseases. 98, p. 18-20 3 p.

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32 引文斯高帕斯（Scopus）

Deep Learning Algorithms for Detection of Diabetic Retinopathy in Retinal Fundus Photographs: A Systematic Review and Meta-Analysis

Islam, M. M., Yang, H-C., Poly, T. N., Jian, W-S. & Li, Y-C., 7月 2020, 於: Computer Methods and Programs in Biomedicine. 191, p. 105320 105320.

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63 引文斯高帕斯（Scopus）

Deep Learning Approach for the Development of a Novel Predictive Model for Prostate Cancer

Islam, M., Yang, H. C., Nguyen, P. A., Wang, Y. H., Poly, T. N. & Li, Y. C. J., 6月 16 2020, 於: Studies in Health Technology and Informatics. 270, p. 1241-1242 2 p.

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2 引文斯高帕斯（Scopus）

Deep Learning for Accurate Diagnosis of Glaucomatous Optic Neuropathy Using Digital Fundus Image: A Meta-Analysis

Islam, M., Poly, T. N., Yang, H. C., Atique, S. & Li, Y. C. J., 6月 16 2020, 於: Studies in Health Technology and Informatics. 270, p. 153-157 5 p.

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4 引文斯高帕斯（Scopus）

Development of an artificial intelligence–based automated recommendation system for clinical laboratory tests: Retrospective analysis of the national health insurance database

Islam, M., Yang, H. C., Poly, T. N. & Jack Li, Y. C., 11月 2020, 於: JMIR medical informatics. 8, 11, e24163.

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6 引文斯高帕斯（Scopus）

Development of nanosome-encapsulated honokiol for intravenous therapy against experimental autoimmune encephalomyelitis

Hsiao, Y. P., Chen, H. T., Liang, Y. C., Wang, T. E., Huang, K. H., Hsu, C. C., Liang, H. J., Huang, C. H. & Jan, T. R., 1月 1 2020, 於: International Journal of Nanomedicine. 15, p. 17-29 13 p.

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9 引文斯高帕斯（Scopus）

Direct and label-free determination of human glycated hemoglobin levels using bacteriorhodopsin as the biosensor transducer

Lin, Y. C., Lin, C. Y., Chen, H. M., Kuo, L. P., Hsieh, C. E., Wang, X. H., Cheng, C. W., Wu, C. Y. & Chen, Y. S., 12月 2 2020, 於: Sensors (Switzerland). 20, 24, p. 1-14 14 p., 7274.

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8 引文斯高帕斯（Scopus）

Engineering Chimeric Antigen Receptor T Cells against Immune Checkpoint Inhibitors PD-1/PD-L1 for Treating Pancreatic Cancer

Yang, C. Y., Fan, M. H., Miao, C. H., Liao, Y. J., Yuan, R. H. & Liu, C. L., 6月 26 2020, 於: Molecular Therapy - Oncolytics. 17, p. 571-585 15 p.

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25 引文斯高帕斯（Scopus）

Envenomation by Trimeresurus stejnegeri stejnegeri: Clinical manifestations, treatment and associated factors for wound necrosis

Chiang, L. C., Tsai, W. J., Liu, P. Y., Ho, C. H., Su, H. Y., Lai, C. S., Lai, K. L., Lin, W. L., Lee, C. H., Yang, Y. Y., Doan, U. V., Maharani, T. & Mao, Y. C., 2020, 於: Journal of Venomous Animals and Toxins Including Tropical Diseases. 26, e20200043.

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9 引文斯高帕斯（Scopus）

Erratum: Healthcare quality-improvement and measurement strategies and its challenges ahead

Iqbal, U., Humayun, A. & Li, Y. C. J., 12月 15 2020, 於: International journal for quality in health care : journal of the International Society for Quality in Health Care. 32, 10, p. 722 1 p.

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Expression, purification, and characterization of anti-Zika virus envelope protein: Polyclonal and chicken-derived single chain variable fragment antibodies

Mwale, P. F., Lee, C. H., Lin, L. T., Leu, S. J., Huang, Y. J., Chiang, L. C., Mao, Y. C. & Yang, Y. Y., 1月 13 2020, 於: International Journal of Molecular Sciences. 21, 2, 492.

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8 引文斯高帕斯（Scopus）

Focal TLR4 activation mediates disturbed flow-induced endothelial inflammation

Qu, D., Wang, L., Huo, M., Song, W., Lau, C. W., Xu, J., Xu, A., Yao, X., Chiu, J. J., Tian, X. Y. & Huang, Y., 1月 1 2020, 於: Cardiovascular Research. 116, 1, p. 226-236 11 p.

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31 引文斯高帕斯（Scopus）

Generation and Characterization of Single Chain Variable Fragment against Alpha-Enolase of Candida albicans

Leu, S. J., Lee, Y. C., Lee, C. H., Liao, P. Y., Chiang, C. W., Yang, C. M., Su, C. H., Ou, T. Y., Liu, K. J., Lo, H. J., Tsai, B. Y. & Yang, Y. Y., 4月 21 2020, 於: International journal of molecular sciences. 21, 8, 2903.

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6 引文斯高帕斯（Scopus）

Incorporating deep learning and multi-omics autoencoding for analysis of lung adenocarcinoma prognostication

Lee, T. Y., Huang, K. Y., Chuang, C. H., Lee, C. Y. & Chang, T. H., 8月 2020, 於: Computational Biology and Chemistry. 87, 107277.

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26 引文斯高帕斯（Scopus）

Increase Risk of Dementia in Patients With Sudden Hearing Loss: A Population-Based Cohort Study With 7-Year Follow-Up in Taiwan

Lin, C. C., Lin, H. C. & Chiu, H. W., 12月 1 2020, 於: Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 41, 10, p. 1334-1340 7 p.

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Inhibition of alternative cancer cell metabolism of egfr mutated non-small cell lung cancer serves as a potential therapeutic strategy

Huang, C. Y., Hsu, L. H., Chen, C. Y., Chang, G. C., Chang, H. W., Hung, Y. M., Liu, K. J. & Kao, S. H., 1月 2020, 於: Cancers. 12, 1, 181.

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14 引文斯高帕斯（Scopus）

Inhibition of miR-21 alleviated cardiac perivascular fibrosis via repressing EndMT in T1DM

Li, Q., Yao, Y., Shi, S., Zhou, M., Zhou, Y., Wang, M., Chiu, J. J., Huang, Z., Zhang, W., Liu, M., Wang, Q. & Tu, X., 1月 1 2020, 於: Journal of Cellular and Molecular Medicine. 24, 1, p. 910-920 11 p.

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27 引文斯高帕斯（Scopus）

Isolation of anti-VEGF monoclonal antibodies with neutralizing effects from an Astragalus-induced immune antibody library

Lee, Y. C., Huang, H. T., Chang, C. D., Chen, C. T., Lin, T. Y., Yang, T. W., Chang, F. L., Lu, M. K., Chiou, C. T., Chen, W. C., Pan, S. L. & Tsai, K. C., 11月 1 2020, 於: International Immunopharmacology. 88, 107007.

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3 引文斯高帕斯（Scopus）

Long-term exposure to low-dose di-(2-ethylhexyl) phthalate impairs cholesterol metabolism in hepatic stellate cells and exacerbates liver librosis

Lee, C. Y., Suk, F. M., Twu, Y. C. & Liao, Y. J., 6月 1 2020, 於: International journal of environmental research and public health. 17, 11, 3802.

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13 引文斯高帕斯（Scopus）

Loss of HMGCS2 enhances lipogenesis and attenuates the protective effect of the ketogenic diet in liver cancer

Wang, Y. H., Suk, F. M. & Liao, Y. J., 7月 2020, 於: Cancers. 12, 7, p. 1-16 16 p., 1797.

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14 引文斯高帕斯（Scopus）

Machine learning approach to reduce alert fatigue using a disease medication–related clinical decision support system: Model development and validation

Poly, T. N., Islam, M. M., Muhtar, M. S., Yang, H. C., Nguyen, P. A. & Li, Y. C., 11月 2020, 於: JMIR medical informatics. 8, 11, e19489.

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9 引文斯高帕斯（Scopus）

Mitochondrial function in modulating human granulosa cell steroidogenesis and female fertility

Urs, D. B. S., Wu, W. H., Komrskova, K., Postlerova, P., Lin, Y. F., Tzeng, C. R. & Kao, S. H., 5月 2 2020, 於: International journal of molecular sciences. 21, 10, 3592.

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36 引文斯高帕斯（Scopus）

Modulation of tumor microenvironment using a TLR-7/8 agonist-loaded nanoparticle system that exerts low-temperature hyperthermia and immunotherapy for in situ cancer vaccination

Chen, P. M., Pan, W. Y., Wu, C. Y., Yeh, C. Y., Korupalli, C., Luo, P. K., Chou, C. J., Chia, W. T. & Sung, H. W., 2月 2020, 於: Biomaterials. 230, 119629.

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64 引文斯高帕斯（Scopus）

Multi-gene signature of microcalcification and risk prediction among Taiwanese breast cancer

Tsai, H. T., Huang, C. S., Tu, C. C., Liu, C. Y., Huang, C. J., Ho, Y. S., Tu, S. H., Tseng, L. M. & Huang, C. C., 12月 1 2020, 於: Scientific Reports. 10, 1, 18276.

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16 引文斯高帕斯（Scopus）

Pilot Study to Establish a Novel Five-Gene Biomarker Panel for Predicting Lymph Node Metastasis in Patients With Early Stage Endometrial Cancer

Huang, C. Y., Liao, K. W., Chou, C. H., Shrestha, S., Yang, C. D., Chiew, M. Y., Huang, H. T., Hong, H. C., Huang, S. H., Chang, T. H. & Huang, H. D., 1月 21 2020, 於: Frontiers in Oncology. 9, 1508.

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12 引文斯高帕斯（Scopus）

Preclinical evaluation of the novel small-molecule msi-n1014 for treating drug-resistant colon cancer via the lgr5/β-catenin/mir-142-3p network and reducing cancer-associated fibroblast transformation

Yadav, V. K., Huang, Y. J., George, T. A., Wei, P. L., Sumitra, M. R., Ho, C. L., Chang, T. H., Wu, A. T. H. & Huang, H. S., 6月 16 2020, 於: Cancers. 12, 6, p. 1-15 15 p., 1590.

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14 引文斯高帕斯（Scopus）

Predicting major neurologic improvement and long-term outcome after thrombolysis using artificial neural networks

Chung, C. C., Hong, C. T., Huang, Y. H., Su, E. C. Y., Chan, L., Hu, C. J. & Chiu, H. W., 3月 15 2020, 於: Journal of the Neurological Sciences. 410, 116667.

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9 引文斯高帕斯（Scopus）

Protective evaluation of compounds extracted from root of rhodiola rosea L. Against methylglyoxal-induced toxicity in a neuronal cell line

Wang, C. H., Safwan, S., Cheng, M. C., Liao, T. Y., Cheng, L. C., Chen, T. A., Kuo, Y. H., Lin, Y. F. & Lee, C. K., 6月 17 2020, 於: Molecules. 25, 12, 2801.

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8 引文斯高帕斯（Scopus）

Radiomic immunophenotyping of gsea-assessed immunophenotypes of glioblastoma and its implications for prognosis: A feasibility study

Hsu, J. B. K., Lee, G. A., Chang, T. H., Huang, S. W., Le, N. Q. K., Chen, Y. C., Kuo, D. P., Li, Y. T. & Chen, C. Y., 10月 2020, 於: Cancers. 12, 10, p. 1-16 16 p., 3039.

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15 引文斯高帕斯（Scopus）

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