癌症生物學與藥物研發博士學位學程

  • No. 250 Wu-Xing Street

    11031 Taipei

研究成果 1996 2020

篩選
文章
2015
16 引文 (Scopus)

Paxillin promotes colorectal tumor invasion and poor patient outcomes via ERK-mediated stabilization of Bcl-2 protein by phosphorylation at Serine 87

Huang, C. C., Wu, D. W., Lin, P. L. & Lee, H., 2015, 於 : Oncotarget. 6, 11, p. 8698-8708 11 p.

研究成果: 雜誌貢獻文章

Paxillin
Serine
Colorectal Neoplasms
Phosphorylation
Proteins
48 引文 (Scopus)

Phase i study of nanoliposomal irinotecan (PEP02) in advanced solid tumor patients

Chang, T. C., Shiah, H. S., Yang, C. H., Yeh, K. H., Cheng, A. L., Shen, B. N., Wang, Y. W., Yeh, C. G., Chiang, N. J., Chang, J. Y. & Chen, L. T., 一月 1 2015, 於 : Cancer Chemotherapy and Pharmacology. 75, 3, p. 579-586 8 p.

研究成果: 雜誌貢獻文章

irinotecan
Tumors
Pharmacokinetics
Toxicity
Neoplasms
8 引文 (Scopus)
HCT116 Cells
Histone Deacetylase Inhibitors
Histone Deacetylases
Oncology
Poisons
4 引文 (Scopus)

Quantitative proteomics reveals middle infrared radiation-interfered networks in breast cancer cells

Chang, H. Y., Li, M. H., Huang, T. C., Hsu, C. L., Tsai, S. R., Lee, S. C., Huang, H. C. & Juan, H. F., 二月 6 2015, 於 : Journal of Proteome Research. 14, 2, p. 1250-1262 13 p.

研究成果: 雜誌貢獻文章

Proteomics
Cells
Radiation
Breast Neoplasms
Infrared radiation
2 引文 (Scopus)

Quercetin, a main flavonoid in onion, inhibits the PGF-induced uterine contraction in vitro and in vivo

Wu, C. H., Shieh, T. M., Wang, K. L., Huang, T. C. & Hsia, S. M., 十二月 1 2015, 於 : Journal of Functional Foods. 19, p. 495-504 10 p., 1300.

研究成果: 雜誌貢獻文章

uterine contraction
Uterine Contraction
Dinoprost
Onions
Quercetin
2 引文 (Scopus)

Receptor proteins for nongenomic actions of thyroid hormone

Davis, P. J., Leonard, J. L., Lin, H. Y., Incerpi, S., Luidens, M. K., Tang, H. Y. & Mousa, S. A., 七月 1 2015, 於 : Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry. 15, 1, p. 94-97 4 p.

研究成果: 雜誌貢獻文章

Thyroid Hormone Receptors
Thyroid Hormones
Cell Membrane
Thyronines
Hormones
12 引文 (Scopus)

Ring fusion strategy for synthesis and lead optimization of sulfur-substituted anthra[1,2-c[[1,2,5]thiadiazole-6,11-dione derivatives as promising scaffold of antitumor agents

Lee, Y. R., Chen, T. C., Lee, C. C., Chen, C. L., Ahmed Ali, A. A., Tikhomirov, A., Guh, J. H., Yu, D. S. & Huang, H. S., 九月 18 2015, 於 : European Journal of Medicinal Chemistry. 102, p. 661-676 16 p.

研究成果: 雜誌貢獻文章

Sulfur
Scaffolds
Antineoplastic Agents
Fusion reactions
Apoptosis
7 引文 (Scopus)

RRM2B-mediated regulation of mitochondrial activity and inflammation under oxidative stress

Cho, E. C., Kuo, M. L., Cheng, J. H., Cheng, Y. C., Hsieh, Y. C., Liu, Y. R., Hsieh, R. H. & Yen, Y., 2015, 於 : Mediators of Inflammation. 2015, 287345.

研究成果: 雜誌貢獻文章

Ribonucleotide Reductases
Oxidative Stress
Inflammation
Mitochondrial Genes
DNA Damage
27 引文 (Scopus)

S-adenosyl-L-methionine-competitive inhibitors of the histone methyltransferase EZH2 induce autophagy and enhance drug sensitivity in cancer cells

Liu, T. P., Lo, H. L., Wei, L. S., Hsiao, H. H. Y. & Yang, P. M., 2015, 於 : Anti-Cancer Drugs. 26, 2, p. 139-147 9 p.

研究成果: 雜誌貢獻文章

S-Adenosylmethionine
Autophagy
Pharmaceutical Preparations
Neoplasms
Antineoplastic Agents
17 引文 (Scopus)

Structure-based hybridization, synthesis and biological evaluation of novel tetracyclic heterocyclic azathioxanthone analogues as potential antitumor agents

Chen, T. C., Wu, C. L., Lee, C. C., Chen, C. L., Yu, D. S. & Huang, H. S., 十月 20 2015, 於 : European Journal of Medicinal Chemistry. 103, p. 615-627 13 p.

研究成果: 雜誌貢獻文章

Antineoplastic Agents
Inhibitory Concentration 50
Assays
Cytostatic Agents
Caspase 3

Synthesis and biological evaluation of anthra[1,9-cd]pyrazol-6(2H)-one scaffold derivatives as potential anticancer agents

Chen, T. C., Guh, J. H., Hsu, H. W., Chen, C. L., Lee, C. C., Wu, C. L., Lee, Y. R., Lin, J. J., Yu, D. S. & Huang, H. S., 2015, 於 : Arabian Journal of Chemistry.

研究成果: 雜誌貢獻文章

Scaffolds
Antineoplastic Agents
Cells
Derivatives
losoxantrone
1 引文 (Scopus)

Synthesis and evaluation of new 3-substituted-4-chloro-thioxanthone derivatives as potent anti-breast cancer agents

Chen, C. L., Chen, T. C., Lee, C. C., Shih, L. C., Lin, C. Y., Hsieh, Y. Y., Ali, A. A. A. & Huang, H. S., 2015, 於 : Arabian Journal of Chemistry.

研究成果: 雜誌貢獻文章

Cells
Derivatives
thioxanthone
Screening
Molecules
23 引文 (Scopus)

Targeting of multiple oncogenic signaling pathways by Hsp90 inhibitor alone or in combination with berberine for treatment of colorectal cancer

Su, Y-H., Tang, W. C., Cheng, Y. W., Sia, P., Huang, C. C., Lee, Y. C., Jiang, H. Y., Wu, M. H., Lai, I. L., Lee, J. W. & Lee, K. H., 十月 1 2015, 於 : Biochimica et Biophysica Acta - Molecular Cell Research. 1853, 10, p. 2261-2272 12 p.

研究成果: 雜誌貢獻文章

Berberine
HSP90 Heat-Shock Proteins
Colorectal Neoplasms
Chemical Databases
Catenins
32 引文 (Scopus)

The MZF1/c-MYC axis mediates lung adenocarcinoma progression caused by wild-type lkb1 loss

Tsai, L. H., Wu, J. Y., Cheng, Y. W., Chen, C. Y., Sheu, G. T., Wu, T. C. & Lee, H., 三月 26 2015, 於 : Oncogene. 34, 13, p. 1641-1649 9 p.

研究成果: 雜誌貢獻文章

Phosphotransferases
Liver
Neoplasms
Adenocarcinoma of lung
Mutation
11 引文 (Scopus)

The novel ribonucleotide reductase inhibitor COH29 inhibits DNA repair in vitros

Chen, M. C., Zhou, B., Zhang, K., Yuan, Y. C., Un, F., Hu, S., Chou, C. M., Chen, C. H., Wu, J., Wang, Y., Liu, X., Smith, D. L., Li, H., Liu, Z., Warden, C. D., Su, L., Malkas, L. H., Chung, Y. M., Hu, M. C. T. & Yen, Y., 六月 1 2015, 於 : Molecular Pharmacology. 87, 6, p. 996-1005 10 p.

研究成果: 雜誌貢獻文章

Ribonucleotide Reductases
DNA Repair
DNA Damage
gemcitabine
Deoxyribonucleotides
19 引文 (Scopus)

The pan-PI3K inhibitor GDC-0941 activates canonical WNT signaling to confer resistance in TNBC cells: Resistance reversal with WNT inhibitor

Tzeng, H. E., Yang, L., Chen, K., Wang, Y., Liu, Y. R., Pan, S. L., Gaur, S., Hu, S. & Yen, Y., 2015, 於 : Oncotarget. 6, 13, p. 11061-11073 13 p.

研究成果: 雜誌貢獻文章

Triple Negative Breast Neoplasms
Phosphatidylinositol 3-Kinases
beta Catenin
MCF-7 Cells
2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine
26 引文 (Scopus)

The synergic effect of vincristine and vorinostat in leukemia in vitro and in vivo

Chao, M-W., Lai, M-J., Liou, J. P., Chang, Y-L., Wang, J-C., Pan, S. L. & Teng, C-M., 十二月 12 2015, 於 : Journal of Hematology and Oncology. 8, 1, 176.

研究成果: 雜誌貢獻文章

Vincristine
Leukemia
Microtubules
Tubulin
Cell Survival
9 引文 (Scopus)

Thyroid hormones crosstalk with growth factors: Old facts and new hypotheses

Candelotti, E., Vito, P. D., Ahmed, R. G., Luly, P., Davis, P. J., Pedersen, J. Z., Lin, H. Y. & Incerpi, S., 七月 1 2015, 於 : Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry. 15, 1, p. 71-85 15 p.

研究成果: 雜誌貢獻文章

Thyroid Hormones
Intercellular Signaling Peptides and Proteins
Integrins
Interleukins
Cell Membrane
50 引文 (Scopus)

Transforming growth factor-β promotes prostate bone metastasis through induction of microRNA-96 and activation of the mTOR pathway

Siu, M. K., Tsai, Y. C., Chang, Y. S., Yin, J. J., Suau, F., Chen, W. Y. & Liu, Y. N., 九月 3 2015, 於 : Oncogene. 34, 36, p. 4767-4776 10 p.

研究成果: 雜誌貢獻文章

Transforming Growth Factors
Sirolimus
MicroRNAs
Prostate
Neoplasm Metastasis
23 引文 (Scopus)

Underexpression of LKB1 tumor suppressor is associated with enhanced Wnt signaling and malignant characteristics of human intrahepatic cholangiocarcinoma

Wang, J., Zhang, K., Wang, J., Wu, X., Liu, X., Li, B., Zhu, Y., Yu, Y., Cheng, Q., Hu, Z., Guo, C., Hu, S., Mu, B., Tsai, C. H., Li, J., Smith, L., Yang, L., Liu, Q., Chu, P., Chang, V. 及其他4, Zhang, B., Wu, M., Jiang, X. & Yen, Y., 2015, 於 : Oncotarget. 6, 22, p. 18905-18920 16 p.

研究成果: 雜誌貢獻文章

Cholangiocarcinoma
Phosphotransferases
Liver
Catenins
Neoplasms
2014
27 引文 (Scopus)

A gene expression signature-based approach reveals the mechanisms of action of the Chinese herbal medicine berberine

Lee, K. H., Lo, H. L., Tang, W. C., Hsiao, H. H. Y. & Yang, P. M., 2014, 於 : Scientific Reports. 4, 6394.

研究成果: 雜誌貢獻文章

Berberine
Herbal Medicine
Transcriptome
Histone Deacetylases
Sirolimus
12 引文 (Scopus)

A germline missense mutation in COQ6 is associated with susceptibility to familial schwannomatosis

Zhang, K., Lin, J. W., Wang, J., Wu, X., Gao, H., Hsieh, Y. C., Hwu, P., Liu, Y. R., Su, L., Chiou, H. Y., Wang, D., Yuan, Y. C., Whang-Peng, J., Chiu, W. T. & Yen, Y., 十月 1 2014, 於 : Genetics in Medicine. 16, 10, p. 787-792 6 p.

研究成果: 雜誌貢獻文章

Germ-Line Mutation
Missense Mutation
coenzyme Q10
Genome
Exome
41 引文 (Scopus)

A lytic viral long noncoding RNA modulates the function of a latent protein

Campbell, M., Kim, K. Y., Chang, P. C., Huerta, S., Shevchenko, B., Wang, D. H., Izumiya, C., Kung, H. J. & Izumiya, Y., 二月 1 2014, 於 : Journal of Virology. 88, 3, p. 1843-1848 6 p.

研究成果: 雜誌貢獻文章

nuclear antigens
Long Noncoding RNA
Human herpesvirus 8
Human Herpesvirus 8
plasmids
93 引文 (Scopus)

AMPK reverses the mesenchymal phenotype of cancer cells by targeting the Akt-MDM2-Foxo3a signaling axis

Chou, C. C., Lee, K. H., Lai, I. L., Wang, D., Mo, X., Kulp, S. K., Shapiro, C. L. & Chen, C. S., 九月 1 2014, 於 : Cancer Research. 74, 17, p. 4783-4795 13 p.

研究成果: 雜誌貢獻文章

AMP-Activated Protein Kinases
Epithelial-Mesenchymal Transition
Phenotype
Neoplasms
Ubiquitin-Protein Ligases
3 引文 (Scopus)

An improved ChIP-seq peak detection system for simultaneously identifying post-translational modified transcription factors by combinatorial fusion, using SUMOylation as an example

Cheng, C. Y., Chu, C. H., Hsu, H. W., Hsu, F. R., Tang, C. Y., Wang, W. C., Kung, H. J. & Chang, P. C., 一月 24 2014, 於 : BMC Genomics. 15, p. 1-14 14 p.

研究成果: 雜誌貢獻文章

Sumoylation
Chromatin Immunoprecipitation
Transcription Factors
Binding Sites
Post Translational Protein Processing
7 引文 (Scopus)

A novel action mechanism for MPT0g013, a derivative of arylsulfonamide, inhibits tumor angiogenesis through upregulation of TIMP3 expression

Wang, C-Y., Liou, J. P., Tsai, A-C., Lai, M-J., Liu, Y-M., Lee, H. Y., Wang, J-C., Pan, S. L. & Teng, C-M., 2014, 於 : Oncotarget. 5, 20, p. 9838-9850 13 p.

研究成果: 雜誌貢獻文章

Tissue Inhibitor of Metalloproteinase-3
Up-Regulation
Neoplasms
Cell Cycle Resting Phase
Proteins
23 引文 (Scopus)
Histone Deacetylases
Cadherins
Protein Kinase C
Cell Differentiation
Colorectal Neoplasms
4 引文 (Scopus)

A novel compound NSC745885 exerts an anti-tumor effect on tongue cancer SAS cells in vitro and in vivo

Chen, Y. W., Huang, H. S., Shieh, Y. S., Ma, K. H., Huang, S. H., Hueng, D. Y., Sytwu, H. K. & Lin, G. J., 八月 15 2014, 於 : PLoS One. 9, 8, e104703.

研究成果: 雜誌貢獻文章

Tongue Neoplasms
tongue
Doxorubicin
Tumors
Anthracyclines
17 引文 (Scopus)
Histone Deacetylases
Human Activities
Refractory materials
Prostatic Neoplasms
Display devices
43 引文 (Scopus)

Anti-proliferative and gene expression actions of resveratrol in breast cancer cells in vitro

Chin, Y. T., Hsieh, M. T., Yang, S. H., Tsai, P. W., Wang, S. H., Wang, C. C., Lee, Y. S., Cheng, G. Y., HuangFu, W. C., London, D., Tang, H. Y., Fu, E., Yen, Y., Liu, L. F., Lin, H. Y. & Davis, P. J., 2014, 於 : Oncotarget. 5, 24, p. 12891-12907 17 p.

研究成果: 雜誌貢獻文章

Breast Neoplasms
Gene Expression
Stilbenes
Cell Proliferation
Perfusion
53 引文 (Scopus)

Arginine starvation-associated atypical cellular death involves mitochondrial dysfunction, nuclear DNA leakage, and chromatin autophagy

Changou, C. A., Chen, Y. R., Xing, L., Yen, Y., Chuang, F. Y. S., Cheng, R. H., Bold, R. J., Ann, D. K. & Kung, H. J., 九月 30 2014, 於 : Proceedings of the National Academy of Sciences of the United States of America. 111, 39, p. 14147-14152 6 p.

研究成果: 雜誌貢獻文章

Autophagy
Starvation
Chromatin
Arginine
DNA
20 引文 (Scopus)

AR-regulated TWEAK-FN14 pathway promotes prostate cancer bone metastasis

Yin, J., Liu, Y. N., Tillman, H., Barrett, B., Hewitt, S., Ylaya, K., Fang, L., Lake, R., Corey, E., Morrissey, C., Vessella, R. & Kelly, K., 八月 15 2014, 於 : Cancer Research. 74, 16, p. 4306-4317 12 p.

研究成果: 雜誌貢獻文章

Bone Neoplasms
Androgen Receptors
Prostatic Neoplasms
Neoplasm Metastasis
Bone and Bones
10 引文 (Scopus)
Sirolimus
Human Activities
Prostatic Neoplasms
Phosphotransferases
Hormones
36 引文 (Scopus)

Autophagy pathway is required for IL-6 induced neuroendocrine differentiation and chemoresistance of prostate cancer LNCaP cells

Chang, P. C., Wang, T. Y., Chang, Y. T., Chu, C. Y., Lee, C. L., Hsu, H. W., Zhou, T. A., Wu, Z., Kim, R. H., Desai, S. J., Liu, S. & Kung, H. J., 二月 14 2014, 於 : PLoS One. 9, 2, e88556.

研究成果: 雜誌貢獻文章

autophagy
Autophagy
prostatic neoplasms
interleukin-6
Interleukin-6
26 引文 (Scopus)

Autophagy promotes radiation-induced senescence but inhibits bystander effects in human breast cancer cells

Huang, Y. H., Yang, P. M., Chuah, Q. Y., Lee, Y. J., Hsieh, Y. F., Peng, C. W. & Chiu, S. J., 2014, 於 : Autophagy. 10, 7, p. 1212-1228 17 p.

研究成果: 雜誌貢獻文章

Bystander Effect
Autophagy
Radiation
Breast Neoplasms
Neoplasms
21 引文 (Scopus)

A vaccine targeted at CETP alleviates high fat and high cholesterol diet-induced atherosclerosis and non-alcoholic steatohepatitis in rabbit

Liaw, Y. W., Lin, C. Y., Lai, Y. S., Yang, T. C., Wang, C. J., Whang-Peng, J., Liu, L. F., Lin, C. P., Nieh, S., Lu, S. C. & Hwang, J., 十二月 8 2014, 於 : PLoS One. 9, 12, e111529.

研究成果: 雜誌貢獻文章

cholesteryl ester transfer protein
Cholesterol Ester Transfer Proteins
High Fat Diet
Fatty Liver
high fat diet
35 引文 (Scopus)

Azaindolylsulfonamides, with a more selective inhibitory effect on histone deacetylase 6 activity, exhibit antitumor activity in colorectal cancer HCT116 cells

Lee, H. Y., Tsai, A. C., Chen, M. C., Shen, P. J., Cheng, Y. C., Kuo, C. C., Pan, S. L., Liu, Y. M., Liu, J. F., Yeh, T. K., Wang, J. C., Chang, C. Y., Chang, J. Y. & Liou, J. P., 五月 22 2014, 於 : Journal of Medicinal Chemistry. 57, 10, p. 4009-4022 14 p.

研究成果: 雜誌貢獻文章

HCT116 Cells
Histone Deacetylases
Colorectal Neoplasms
Histone Deacetylase Inhibitors
Heterografts
24 引文 (Scopus)

Berberis libanotica ehrenb extract shows anti-neoplastic effects on prostate cancer stem/progenitor cells

El-Merahbi, R., Liu, Y. N., Eid, A., Daoud, G., Hosry, L., Monzer, A., Mouhieddine, T. H., Hamade, A., Najjar, F. & Abou-Kheir, W., 十一月 7 2014, 於 : PLoS One. 9, 11, e112453.

研究成果: 雜誌貢獻文章

Berberis
Neoplastic Stem Cells
prostatic neoplasms
Stem cells
stem cells
9 引文 (Scopus)

Biologically active leptin-related synthetic peptides activate STAT3 via phosphorylation of ERK1/2 and PI-3K

Lin, H. Y., Yang, S. H., Tang, H. Y., Cheng, G. Y., Davis, P. J. & Grasso, P., 2014, 於 : Peptides. 57, p. 95-100 6 p.

研究成果: 雜誌貢獻文章

Phosphorylation
Leptin
Phosphatidylinositol 3-Kinases
Chemical activation
Signal transduction
64 引文 (Scopus)

Cancer: Arginine starvation impairs mitochondrial respiratory function in ASS1-deficient breast cancer cells

Qiu, F., Chen, Y. R., Liu, X., Chu, C. Y., Shen, L. J., Xu, J., Gaur, S., Forman, H. J., Zhang, H., Zheng, S., Yen, Y., Huang, J., Kung, H. J. & Ann, D. K., 四月 1 2014, 於 : Science Signaling. 7, 319

研究成果: 雜誌貢獻文章

Argininosuccinate Synthase
Starvation
Arginine
Cells
Breast Neoplasms
6 引文 (Scopus)

Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells

Cheng, C. C., Lee, Y. H., Lin, S. P., Huangfu, W. C. & Liu, I. H., 三月 13 2014, 於 : Journal of Biomedical Science. 21, 1, 21.

研究成果: 雜誌貢獻文章

Stem cells
Mesenchymal Stromal Cells
Bone
Bone Marrow
Heparitin Sulfate
10 引文 (Scopus)

Circulating anti-cyclic citrullinated peptide antibody in patients with rheumatoid arthritis and chronic obstructive pulmonary disease

Yang, D. H., Tu, C. C., Wang, S. C., Wei, C. C. & Cheng, Y. W., 2014, 於 : Rheumatology International. 34, 7, p. 971-977 7 p.

研究成果: 雜誌貢獻文章

Chronic Obstructive Pulmonary Disease
Rheumatoid Arthritis
Antibodies
Rheumatoid Factor
Smoking
3 引文 (Scopus)

Clinical research of mortality in emergency air medical transport

Chen, W. L., Ma, H. P., Wu, C. H., Chiou, H. Y., Yen, Y., Chiu, W. T. & Tsai, S. H., 2014, 於 : BioMed Research International. 2014, 767402.

研究成果: 雜誌貢獻文章

Health care
Emergencies
Air
Mortality
Taiwan
45 引文 (Scopus)

C-Myc suppresses microRNA-29b to promote tumor aggressiveness and poor outcomes in non-small cell lung cancer by targeting FHIT

Wu, D. W., Hsu, N. Y., Wang, Y. C., Lee, M. C., Cheng, Y. W., Chen, C. Y. & Lee, H., 六月 9 2014, 於 : Oncogene. 34, 16, p. 2072-2082 11 p.

研究成果: 雜誌貢獻文章

MicroRNAs
Non-Small Cell Lung Carcinoma
Neoplasms
Survival
Agar
14 引文 (Scopus)

Combination therapy targeting ectopic ATP synthase and 26S proteasome induces ER stress in breast cancer cells

Chang, H. Y., Huang, T. C., Chen, N. N., Huang, H. C. & Juan, H. F., 一月 1 2014, 於 : Cell Death and Disease. 5, 11, e1540.

研究成果: 雜誌貢獻文章

Adenosine Triphosphate
Breast Neoplasms
Proteasome Inhibitors
Cyclin D3
Therapeutics
157 引文 (Scopus)

Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA

Zuckerman, J. E., Gritli, I., Tolcher, A., Heidel, J. D., Lim, D., Morgan, R., Chmielowski, B., Ribas, A., Davis, M. E. & Yen, Y., 八月 5 2014, 於 : Proceedings of the National Academy of Sciences of the United States of America. 111, 31, p. 11449-11454 6 p.

研究成果: 雜誌貢獻文章

Nanoparticles
Small Interfering RNA
Polymers
Clinical Trials, Phase I
RNA Interference

Curative use of forequarter amputation for recurrent breast cancer over an axillary area: a case report and literature review

Tsai, C. H., Tzeng, H. E., Juang, W. K., Chu, P. G., Fann, P., Fong, Y. C., Hsu, H. C. & Yen, Y., 2014, 於 : World Journal of Surgical Oncology. 12, p. 346 1 p.

研究成果: 雜誌貢獻文章

Amputation
Breast Neoplasms
Recurrence
Neoplasm Metastasis
Upper Extremity
57 引文 (Scopus)

DDX3 loss by p53 inactivation promotes tumor malignancy via the MDM2/Slug/E-cadherin pathway and poor patient outcome in non-small-cell lung cancer

Wu, D. W., Lee, M. C., Wang, J., Chen, C. Y., Cheng, Y. W. & Lee, H., 三月 20 2014, 於 : Oncogene. 33, 12, p. 1515-1526 12 p.

研究成果: 雜誌貢獻文章

Gastropoda
Cadherins
Non-Small Cell Lung Carcinoma
Neoplasms
Lung Neoplasms
37 引文 (Scopus)

Design, synthesis, mechanisms of action, and toxicity of novel 20(s)-sulfonylamidine derivatives of camptothecin as potent antitumor agents

Wang, M. J., Liu, Y. Q., Chang, L. C., Wang, C. Y., Zhao, Y. L., Zhao, X. B., Qian, K., Nan, X., Yang, L., Yang, X. M., Hung, H. Y., Yang, J. S., Kuo, D. H., Goto, M., Morris-Natschke, S. L., Pan, S. L., Teng, C. M., Kuo, S. C., Wu, T. S., Wu, Y. C. 及其他1, Lee, K. H., 七月 24 2014, 於 : Journal of Medicinal Chemistry. 57, 14, p. 6008-6018 11 p.

研究成果: 雜誌貢獻文章

Camptothecin
Type I DNA Topoisomerase
irinotecan
Lethal Dose 50
Antineoplastic Agents
20 引文 (Scopus)
oxaliplatin
Colorectal Neoplasms
Cell Proliferation
Heterografts
Colonic Neoplasms