癌症生物學與藥物研發博士學位學程

  • No. 250 Wu-Xing Street

    11031 Taipei

研究成果

篩選
文章
2016

Elevated HMGA2 expression is associated with cancer aggressiveness and predicts poor outcome in breast cancer

Wu, J., Zhang, S., Shan, J., Hu, Z., Liu, X., Chen, L., Ren, X., Yao, L., Sheng, H., Li, L., Ann, D., Yen, Y., Wang, J. & Wang, X., 七月 1 2016, 於 : Cancer Letters. 376, 2, p. 284-292 9 p.

研究成果: 雜誌貢獻文章

45 引文 斯高帕斯(Scopus)

Environmental exposure and HPV infection may act synergistically to induce lung tumorigenesis in nonsmokers

Cheng, Y. W., Lin, F. C. F., Chen, C. Y. & Hsu, N. Y., 四月 12 2016, 於 : Oncotarget. 7, 15, p. 19850-19862 13 p.

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)

Erlotinib-Conjugated Iron Oxide Nanoparticles as a Smart Cancer-Targeted Theranostic Probe for MRI

Ali, A. A. A., Hsu, F. T., Hsieh, C. L., Shiau, C. Y., Chiang, C. H., Wei, Z. H., Chen, C. Y. & Huang, H. S., 十一月 11 2016, 於 : Scientific Reports. 6, 36650.

研究成果: 雜誌貢獻文章

26 引文 斯高帕斯(Scopus)

Evaluation of the In Vivo Therapeutic Effects of Radix Paeoniae Rubra Ethanol Extract with the Hypoglycemic Activities Measured from Multiple Cell-Based Assays

Chang, C. C., Yuan, W., Lin, Y. L., Liu, R. S., Juan, Y. C., Sun, W. H., Tsay, H. J., Huang, H. C., Lee, Y. C. & Liu, H. K., 一月 1 2016, 於 : Evidence-based Complementary and Alternative Medicine. 2016, 3262790.

研究成果: 雜誌貢獻文章

5 引文 斯高帕斯(Scopus)

Expression levels of estrogen receptor α mRNA in peripheral blood cells are an independent biomarker for postmenopausal osteoporosis

Chou, C. W., Chiang, T. I., Chang, I. C., Huang, C. H. & Cheng, Y. W., 六月 1 2016, 於 : BBA Clinical. 5, p. 124-129 6 p.

研究成果: 雜誌貢獻文章

5 引文 斯高帕斯(Scopus)

Expression Pattern and Clinicopathological Relevance of the Indoleamine 2,3-Dioxygenase 1/Tryptophan 2,3-Dioxygenase Protein in Colorectal Cancer

Chen, I. C., Lee, K. H., Hsu, Y. H., Wang, W. R., Chen, C. M. & Cheng, Y. W., 2016, 於 : Disease Markers. 2016, 8169724.

研究成果: 雜誌貢獻文章

16 引文 斯高帕斯(Scopus)
17 引文 斯高帕斯(Scopus)

Glucocorticoids may compromise the effect of gefitinib in non-small cell lung cancer

Wang, H. Y., Chang, Y. L., Cheng, C. C., Chao, M. W., Lin, S. I., Pan, S-L., Hsu, C. C., Liu, T. W., Cheng, H. C., Tseng, C. P., Liu, S. J., Tsai, H. J., Chang, H. Y. & Hsu, J. T. A., 2016, 於 : Oncotarget. 7, 52, p. 85917-85928 12 p.

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)

Glucose-regulated protein 94 mediates cancer progression via AKT and eNOS in hepatocellular carcinoma

Huang, C. Y., Batzorig, U., Cheng, W. L., Huang, M. T., Chen, W. Y., Wei, P. L. & Chang, Y. J., 四月 1 2016, 於 : Tumor Biology. 37, 4, p. 4295-4304

研究成果: 雜誌貢獻文章

13 引文 斯高帕斯(Scopus)
9 引文 斯高帕斯(Scopus)

HIF-1-alpha links mitochondrial perturbation to the dynamic acquisition of breast cancer tumorigenicity

Kuo, C. Y., Cheng, C. T., Hou, P., Lin, Y. P., Ma, H., Chung, Y., Chi, K., Chen, Y., Li, W., Kung, H. J. & Ann, D. K., 六月 7 2016, 於 : Oncotarget. 7, 23, p. 34052-34069 18 p.

研究成果: 雜誌貢獻文章

7 引文 斯高帕斯(Scopus)

Identification of a new class of WNT1 inhibitor: Cancer cells migration, G-quadruplex stabilization and target validation

Chang, L. C., Chen, T. C., Chen, S. J., Chen, C. L., Lee, C. C., Wu, S. H., Yen, Y., Huang, H. S. & Lin, J. J., 十月 18 2016, 於 : Oncotarget. 7, 42, p. 67986-68001 16 p.

研究成果: 雜誌貢獻文章

Identification of Inhibitors for the DEDDh Family of Exonucleases and a Unique Inhibition Mechanism by Crystal Structure Analysis of CRN-4 Bound with 2-Morpholin-4-ylethanesulfonate (MES)

Huang, K. W., Hsu, K. C., Chu, L. Y., Yang, J. M., Yuan, H. S. & Hsiao, Y. Y., 九月 8 2016, 於 : Journal of Medicinal Chemistry. 59, 17, p. 8019-8029 11 p.

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)

Indole-3-ethylsulfamoylphenylacrylamides with potent anti-proliferative and anti-angiogenic activities

Mehndiratta, S., Pan, S. L., Kumar, S. & Liou, J. P., 七月 1 2016, 於 : Anti-Cancer Agents in Medicinal Chemistry. 16, 7, p. 907-913 7 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)
9 引文 斯高帕斯(Scopus)

Integrin β3 and LKB1 are independently involved in the inhibition of proliferation by lovastatin in human intrahepatic cholangiocarcinoma

Yang, S. H., Lin, H. Y., Changou, C. A., Chen, C. H., Liu, Y. R., Wang, J., Jiang, X., Luh, F. & Yen, Y., 2016, 於 : Oncotarget. 7, 1, p. 362-373 12 p.

研究成果: 雜誌貢獻文章

12 引文 斯高帕斯(Scopus)

Isoliquiritigenin induces apoptosis and autophagy and inhibits endometrial cancer growth in mice

Wu, C-H., Chen, H. Y., Wang, C-W., Shieh, T. M., Huang, T-C., Lin, L. C., Wang, K. L. & Hsia, S-M., 2016, 於 : Oncotarget. 7, 45, p. 73432-73447 16 p.

研究成果: 雜誌貢獻文章

37 引文 斯高帕斯(Scopus)

KLF4 functions as an activator of the androgen receptor through reciprocal feedback

Siu, M-K., Suau, F., Chen, W-Y., Tsai, Y-C., Tsai, H-Y., Yeh, H-L. & Liu, Y-N., 十二月 2016, 於 : Oncogenesis. 5, 12, p. e282

研究成果: 雜誌貢獻文章

LTP-1, a novel antimitotic agent and Stat3 inhibitor, inhibits human pancreatic carcinomas in vitro and in vivo

Huang, H. L., Chao, M. W., Chen, C. C., Cheng, C. C., Chen, M. C., Lin, C. F., Liou, J. P., Teng, C. M. & Pan, S. L., 六月 9 2016, 於 : Scientific Reports. 6, 27794.

研究成果: 雜誌貢獻文章

5 引文 斯高帕斯(Scopus)

Methyl Protodioscin, a Steroidal Saponin, Inhibits Neointima Formation in Vitro and in Vivo

Chung, Y. L., Pan, C. H., Wang, C. C. N., Hsu, K. C., Sheu, M. J., Chen, H. F. & Wu, C. H., 六月 24 2016, 於 : Journal of Natural Products. 79, 6, p. 1635-1644 10 p.

研究成果: 雜誌貢獻文章

7 引文 斯高帕斯(Scopus)

MiR-30c-2* negative regulated MTA-1 expression involved in metastasis and drug resistance of HPV-infected non-small cell lung cancer

Wu, Y. L., Hsu, N-Y., Lin, F. C. F., Lee, H. & Cheng, Y-W., 十二月 1 2016, 於 : Surgery (United States). 160, 6, p. 1591-1598 8 p.

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)
7 引文 斯高帕斯(Scopus)

Novel anthra[1,2-c][1,2,5]thiadiazole-6,11-diones as promising anticancer lead compounds: Biological evaluation, characterization & molecular targets determination

Ali, A. A. A., Lee, Y. R., Chen, T. C., Chen, C. L., Lee, C. C., Shiau, C. Y., Chiang, C. H. & Huang, H. S., 四月 1 2016, 於 : PLoS One. 11, 4, e0154278.

研究成果: 雜誌貢獻文章

11 引文 斯高帕斯(Scopus)

Novel leptin OB3 peptide-induced signaling and progression in thyroid cancers: Comparison with leptin

Yang, Y. C. S. H., Chin, Y. T., Hsieh, M. T., Lai, H. Y., Ke, C. C., Crawford, D. R., Lee, O. K., Fu, E., Mousa, S. A., Grasso, P., Liu, L-F., Chang, H-Y., Tang, H. Y., Lin, H-Y. & Davis, P. J., 五月 10 2016, 於 : Oncotarget. 7, 19, p. 27641-27654 14 p.

研究成果: 雜誌貢獻文章

8 引文 斯高帕斯(Scopus)

Novel regulators and molecular mechanisms of p53R2 and its disease relevance

Cho, E. C. & Yen, Y., 四月 1 2016, 於 : Biochimie. 123, p. 81-84 4 p.

研究成果: 雜誌貢獻文章

12 引文 斯高帕斯(Scopus)

Observation of polarization and thickness dependent third-harmonic generation in multilayer black phosphorus

Wu, H. Y., Yen, Y. & Liu, C. H., 十二月 26 2016, 於 : Applied Physics Letters. 109, 26, 261902.

研究成果: 雜誌貢獻文章

10 引文 斯高帕斯(Scopus)

One-pot green hydrothermal synthesis of fluorescent nitrogen-doped carbon nanodots for in vivo bioimaging

Kuo, T. R., Sung, S. Y., Hsu, C. W., Chang, C. J., Chiu, T. C. & Hu, C. C., 一月 1 2016, 於 : Analytical and Bioanalytical Chemistry. 408, 1, p. 77-82 6 p.

研究成果: 雜誌貢獻文章

18 引文 斯高帕斯(Scopus)

PAK1 confers chemoresistance and poor outcome in non-small cell lung cancer via β-catenin-mediated stemness

Chen, M. J., Wu, D. W., Wang, Y. C., Chen, C. Y. & Lee, H., 十月 7 2016, 於 : Scientific Reports. 6, 34933.

研究成果: 雜誌貢獻文章

18 引文 斯高帕斯(Scopus)
28 引文 斯高帕斯(Scopus)

Paxillin confers resistance to tyrosine kinase inhibitors in EGFR-mutant lung cancers via modulating BIM and Mcl-1 protein stability

Wu, D. W., Chen, C. Y., Chu, C. L. & Lee, H., 二月 4 2016, 於 : Oncogene. 35, 5, p. 621-630 10 p.

研究成果: 雜誌貢獻文章

25 引文 斯高帕斯(Scopus)

Phenyl Benzenesulfonylhydrazides Exhibit Selective Indoleamine 2,3-Dioxygenase Inhibition with Potent in Vivo Pharmacodynamic Activity and Antitumor Efficacy

Lin, S. Y., Yeh, T. K., Kuo, C. C., Song, J. S., Cheng, M. F., Liao, F. Y., Chao, M. W., Huang, H. L., Chen, Y. L., Yang, C. Y., Wu, M. H., Hsieh, C. L., Hsiao, W., Peng, Y. H., Wu, J. S., Lin, L. M., Sun, M., Chao, Y. S., Shih, C., Wu, S. Y. 及其他3, Pan, S. L., Hung, M. S. & Ueng, S. H., 一月 14 2016, 於 : Journal of Medicinal Chemistry. 59, 1, p. 419-430 12 p.

研究成果: 雜誌貢獻文章

44 引文 斯高帕斯(Scopus)

Polygonum multiflorum Decreases Airway Allergic Symptoms in a Murine Model of Asthma

Lee, C. C., Lee, Y. L., Wang, C. N., Tsai, H. C., Chiu, C. L., Liu, L. F., Lin, H. Y. & Wu, R., 二月 1 2016, 於 : American Journal of Chinese Medicine. 44, 1, p. 133-147 15 p.

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)

Precision Medicine and Pancreatic Cancer

Farrell, J. J., Moughan, J., Wong, J. L., Regine, W. F., Schaefer, P., Benson, A. B., Macdonald, J. S., Liu, X., Yen, Y., Lai, R., Zheng, Z., Bepler, G., Guha, C. & Elsaleh, H., 十一月 1 2016, 於 : Pancreas. 45, 10, p. 1485-1493 9 p.

研究成果: 雜誌貢獻文章

6 引文 斯高帕斯(Scopus)
26 引文 斯高帕斯(Scopus)

Primary versus castration-resistant prostate cancer: Modeling through novel murine prostate cancer cell line

Daoud, G., Monzer, A., Bahmad, H., Chamaa, F., Hamdar, L., Mouhieddine, T. H., Shayya, S., Eid, A., Kobeissy, F., Liu, Y. N. & Abou-Kheir, W., 五月 17 2016, 於 : Oncotarget. 7, 20, p. 28961-28975 15 p.

研究成果: 雜誌貢獻文章

8 引文 斯高帕斯(Scopus)

Prognostic and therapeutic value of mitochondrial serine hydroxyl-methyltransferase 2 as a breast cancer biomarker

Zhang, L., Chen, Z., Xue, D., Zhang, Q., Liu, X., Luh, F., Hong, L., Zhang, H., Pan, F., Liu, Y., Chu, P., Zheng, S., Lou, G. & Yen, Y., 十一月 1 2016, 於 : Oncology Reports. 36, 5, p. 2489-2500 12 p.

研究成果: 雜誌貢獻文章

14 引文 斯高帕斯(Scopus)

Proton pump inhibitors and risk of periampullary cancers - A nested case-control study

Chien, L-N., Huang, Y. J., Shao, Y-H., Chang, C. J., Chuang, M. T., Chiou, H-Y. & Yen, Y., 三月 15 2016, 於 : International Journal of Cancer. 138, 6, p. 1401-1409 9 p.

研究成果: 雜誌貢獻文章

17 引文 斯高帕斯(Scopus)

Pu-erh Tea Extract Attenuates Nicotine-Induced Foam Cell Formation in Primary Cultured Monocytes: An in Vitro Mechanistic Study

Tu, S. H., Chen, M. Y., Chen, L. C., Mao, Y. T., Ho, C. H., Lee, W. J., Lin, Y-K., Pan, M. H., Lo, C. Y., Chen, C. L., Yen, Y., Whang-Peng, J., Ho, C. T., Wu, C. H. & Ho, Y. S., 四月 27 2016, 於 : Journal of Agricultural and Food Chemistry. 64, 16, p. 3186-3195 10 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)

PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress

Kuo, M. L., Lee, M. B. E., Tang, M., Den Besten, W., Hu, S., Sweredoski, M. J., Hess, S., Chou, C. M., Chang, O-C., Su, M., Jia, W., Su, L. & Yen, Y., 一月 6 2016, 於 : Scientific Reports. 6, 18846.

研究成果: 雜誌貢獻文章

28 引文 斯高帕斯(Scopus)

Reduction of microRNA-184 by E6 oncoprotein confers cisplatin resistance in lung cancer via increasing Bcl-2

Tung, M. C., Lin, P. L., Cheng, Y. W., Wu, D. W., Yeh, S. D., Chen, C. Y. & Lee, H., 五月 31 2016, 於 : Oncotarget. 7, 22, p. 32362-32374 13 p.

研究成果: 雜誌貢獻文章

22 引文 斯高帕斯(Scopus)
13 引文 斯高帕斯(Scopus)

Research of StemBios cell therapy on dental implants containing nanostructured surfaces: Biomechanical behaviors, microstructural characteristics, and clinical trial

Ou, K. L., Weng, C. C., Wu, C. C., Lin, Y. H., Chiang, H. J., Yang, T. S., Wang, J., Yen, Y., Cheng, H. Y. & Sugiatno, E., 二月 1 2016, 於 : Implant Dentistry. 25, 1, p. 63-73 11 p.

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)

REST reduction is essential for hypoxia-induced neuroendocrine differentiation of prostate cancer cells by activating autophagy signaling

Lin, T. P., Chang, Y. T., Lee, S. Y., Campbell, M., Wang, T. C., Shen, S. H., Chung, H. J., Chang, Y. H., Chiu, A. W., Pan, C. C., Lin, C. H., Chu, C. Y., Kung, H. J., Cheng, C. Y. & Chang, P. C., 五月 1 2016, 於 : Oncotarget. 7, 18, p. 26137-26151 15 p.

研究成果: 雜誌貢獻文章

25 引文 斯高帕斯(Scopus)

Resveratrol inhibits proliferation of myometrial and leiomyoma cells and decreases extracellular matrix-associated protein expression

Wu, C. H., Shieh, T. M., Wei, L. H., Cheng, T. F., Chen, H. Y., Huang, T. C., Wang, K. L. & Hsia, S. M., 五月 1 2016, 於 : Journal of Functional Foods. 23, p. 241-252 12 p.

研究成果: 雜誌貢獻文章

8 引文 斯高帕斯(Scopus)

RINT-1 interacts with MSP58 within nucleoli and plays a role in ribosomal gene transcription

Yang, C. P., Kuo, Y. L., Lee, Y. C., Lee, K. H., Chiang, C. W., Wang, J. M., Hsu, C. C., Chang, W. C. & Lin, D. Y., 九月 16 2016, 於 : Biochemical and Biophysical Research Communications. 478, 2, p. 873-880 8 p.

研究成果: 雜誌貢獻文章

2 引文 斯高帕斯(Scopus)

Selective recognition and stabilization of new ligands targeting the potassium form of the human telomeric G-quadruplex DNA

Lin, Y. H., Chuang, S. M., Wu, P. C., Chen, C. L., Jeyachandran, S., Lo, S. C., Huang, H. S. & Hou, M. H., 八月 11 2016, 於 : Scientific Reports. 6, 31019.

研究成果: 雜誌貢獻文章

9 引文 斯高帕斯(Scopus)

Signature miRNAs in colorectal cancers were revealed using a bias reduction small RNA deep sequencing protocol

Sun, G., Cheng, Y. W., Lai, L., Huang, T. C., Wang, J., Wu, X., Wang, Y., Huang, Y., Wang, J., Zhang, K., Hu, S., Yang, J. R. & Yen, Y., 2016, 於 : Oncotarget. 7, 4, p. 3857-3872 16 p.

研究成果: 雜誌貢獻文章

21 引文 斯高帕斯(Scopus)

Sterol O-acyltransferase 2 contributes to the yolk cholesterol trafficking during zebrafish embryogenesis

Chang, N. Y., Chan, Y. J., Ding, S. T., Lee, Y. H., Huangfu, W. C. & Liu, I. H., 十二月 1 2016, 於 : PLoS One. 11, 12, e0167644.

研究成果: 雜誌貢獻文章

9 引文 斯高帕斯(Scopus)
5 引文 斯高帕斯(Scopus)

TC-N19, a novel dual inhibitor of EGFR and cMET, efficiently overcomes EGFR-TKI resistance in non-small-cell lung cancer cells

Wu, D. W., Chen, T. C., Huang, H. S. & Lee, H., 六月 30 2016, 於 : Cell death & disease. 7, 6, p. e2290

研究成果: 雜誌貢獻文章

16 引文 斯高帕斯(Scopus)