癌症生物學與藥物研發博士學位學程

  • No. 250 Wu-Xing Street

    11031 Taipei

研究成果

2020

A site-moiety map and virtual screening approach for discovery of novel 5-LOX inhibitors

Hsu, K. C., HuangFu, W. C., Lin, T. E., Chao, M. W., Sung, T. Y., Chen, Y. Y., Pan, S. L., Lee, J. C., Tzou, S. C., Sun, C. M. & Yang, J. M., 十二月 1 2020, 於 : Scientific Reports. 10, 1, 10510.

研究成果: 雜誌貢獻文章

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Astragalus membranaceus-Derived Anti-Programmed Death-1 Monoclonal Antibodies with Immunomodulatory Therapeutic Effects against Tumors

Chang, F. L., Tsai, K. C., Lin, T. Y., Yang, T. W., Lo, Y. N., Chen, W. C., Chang, J. H., Lu, M. K., Chiou, C. T., Chen, P. H., Yen, Y., Pan, S. L. & Lee, Y. C., 一月 1 2020, 於 : BioMed Research International. 2020, 3415471.

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3 引文 斯高帕斯(Scopus)

CC12 induces apoptotic cell death and cell cycle arrest in human glioblastoma cell lines and mouse xenograft model

Fann, L. Y., Shih, J. H., Tseng, J. H., Huang, H. S. & Hsiao, S. H., 四月 2020, 於 : Molecules. 25, 8, 25081793.

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Chondroitin sulfate proteoglycan 4 regulates zebrafish body axis organization via Wnt/ planar cell polarity pathway

Lee, Y. H., Kawakami, K., HuangFu, W. C. & Liu, I. H., 一月 1 2020, 於 : PLoS ONE. 15, 4, e0230943.

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Correction: Role of integrin-linked kinase in regulating the protein stability of the MUC1-C oncoprotein in pancreatic cancer cells (Oncogenesis, (2017), 6, 7, (e359), 10.1038/oncsis.2017.61)

Huang, H. L., Wu, H. Y., Chu, P. C., Lai, I. L., Huang, P. H., Kulp, S. K., Pan, S. L., Teng, C. M. & Chen, C. S., 二月 1 2020, 於 : Oncogenesis. 9, 2, 27.

研究成果: 雜誌貢獻評論/辯論

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Gene signatures and potential therapeutic targets of amino acid metabolism in estrogen receptor-positive breast cancer

Wang, C-Y., Chiao, C-C., Phan, N. N., Li, C-Y., Sun, Z-D., Jiang, J-Z., Hung, J-H., Chen, Y-L., Yen, M-C., Weng, T-Y., Chen, W-C., Hsu, H-P. & Lai, M-D., 2020, 於 : American Journal of Cancer Research. 10, 1, p. 95-113 19 p.

研究成果: 雜誌貢獻文章

Gene signatures of SARS-CoV/SARS-CoV-2-infected ferret lungs in short- and long-term models

Liu, H. L., Yeh, I. J., Phan, N. N., Wu, Y. H., Yen, M. C., Hung, J. H., Chiao, C. C., Chen, C. F., Sun, Z., Jiang, J. Z., Hsu, H. P., Wang, C. Y. & Lai, M. D., 十一月 2020, 於 : Infection, Genetics and Evolution. 85, 104438.

研究成果: 雜誌貢獻文章

1 引文 斯高帕斯(Scopus)

Identification of the Effects of Aspirin and Sulindac Sulfide on the Inhibition of HMGA2-Mediated Oncogenic Capacities in Colorectal Cancer

Ekanem, T. I., Tsai, W. L., Lin, Y. H., Tan, W. Q., Chang, H. Y., Huang, T. C., Chen, H. Y. & Lee, K. H., 九月 2020, 於 : Molecules. 25, 17, 3826.

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Increased expression of secreted frizzled related protein 1 (SFRP1) predicts ampullary adenocarcinoma recurrence

Cheng, L. C., Chao, Y. J., Overman, M. J., Wang, C. Y., Phan, N. N., Chen, Y. L., Wang, T. W., Hsu, H. P., Shan, Y. S. & Lai, M. D., 十二月 1 2020, 於 : Scientific Reports. 10, 1, 13255.

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2 引文 斯高帕斯(Scopus)
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Long-term Proton Pump Inhibitor Administration Caused Physiological and Microbiota Changes in Rats

Yang, Y. C. S. H., Chang, H. W., Lin, I. H., Chien, L. N., Wu, M. J., Liu, Y. R., Chu, P. G., Xie, G., Dong, F., Jia, W., Chang, V. H. S. & Yen, Y., 十二月 1 2020, 於 : Scientific Reports. 10, 1, 866.

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1 引文 斯高帕斯(Scopus)

Melatonin activates cell death programs for the suppression of uterine leiomyoma cell proliferation

Lin, P. H., Tung, Y. T., Chen, H. Y., Chiang, Y. F., Hong, H. C., Huang, K. C., Hsu, S. P., Huang, T. C. & Hsia, S. M., 一月 1 2020, 於 : Journal of Pineal Research. 68, 1, p. e12620 e12620.

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)
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Muscle atrophy-related myotube-derived exosomal microRNA in neuronal dysfunction: Targeting both coding and long noncoding RNAs

Yang, C. P., Yang, W. S., Wong, Y. H., Wang, K. H., Teng, Y. C., Chang, M. H., Liao, K. H., Nian, F. S., Chao, C. C., Tsai, J. W., Hwang, W. L., Lin, M. W., Tzeng, T. Y., Wang, P. N., Campbell, M., Chen, L. K., Tsai, T. F., Chang, P. C. & Kung, H. J., 五月 1 2020, 於 : Aging Cell. 19, 5, e13107.

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N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-γ induced PD-L1 expression

Mehndiratta, S., Lin, M. H., Wu, Y. W., Chen, C. H., Wu, T. Y., Chuang, K. H., Chao, M. W., Chen, Y. Y., Pan, S. L., Chen, M. C. & Liou, J. P., 一月 1 2020, 於 : European Journal of Medicinal Chemistry. 185, p. 111725 111725.

研究成果: 雜誌貢獻文章

8 引文 斯高帕斯(Scopus)

Platelet ATP, Thyroid Hormone Receptor on Integrin αvβ3 and Cancer Metastasis

Davis, P. J., Mousa, S. A., Schechter, G. P. & Lin, H. Y., 二月 1 2020, 於 : Hormones and Cancer. 11, 1, p. 13-16 4 p.

研究成果: 雜誌貢獻回顧型文獻

1 引文 斯高帕斯(Scopus)

Ras and Wnt interaction contribute in prostate cancer bone metastasis

Lin, S. R., Mokgautsi, N. & Liu, Y. N., 五月 2020, 於 : Molecules. 25, 10, 2380.

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Signaling in and out: Long-noncoding RNAs in tumor hypoxia

Kuo, T. C., Kung, H. J. & Shih, J. W., 五月 5 2020, 於 : Journal of Biomedical Science. 27, 1, 59.

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Sorafenib inhibits ribonucleotide reductase regulatory subunit M2 (RRM2) in hepatocellular carcinoma cells

Yang, P. M., Lin, L. S. & Liu, T. P., 一月 2020, 於 : Biomolecules. 10, 1, 117.

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1 引文 斯高帕斯(Scopus)
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Synthesis and biological evaluation of acridine-based histone deacetylase inhibitors as multitarget agents against Alzheimer's disease

Tseng, H. J., Lin, M. H., Shiao, Y. J., Yang, Y. C., Chu, J. C., Chen, C. Y., Chen, Y. Y., Lin, T. E., Su, C. J., Pan, S. L., Chen, L. C., Wang, C. Y., Hsu, K. C. & Huang, W. J., 四月 15 2020, 於 : European Journal of Medicinal Chemistry. 192, p. 112193 112193.

研究成果: 雜誌貢獻文章

1 引文 斯高帕斯(Scopus)

Temporal expression patterns of distinct cytokines and M1/M2 macrophage polarization regulate rheumatoid arthritis progression

Kung, C. C., Dai, S. P., Chiang, H., Huang, H. S. & Sun, W. H., 一月 1 2020, (接受/付印) 於 : Molecular Biology Reports.

研究成果: 雜誌貢獻文章

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Two first-in-human studies of xentuzumab, a humanised insulin-like growth factor (IGF)-neutralising antibody, in patients with advanced solid tumours

de Bono, J., Lin, C. C., Chen, L. T., Corral, J., Michalarea, V., Rihawi, K., Ong, M., Lee, J. H., Hsu, C. H., Yang, J. C. H., Shiah, H. S., Yen, C. J., Anthoney, A., Jove, M., Buschke, S., Fuertig, R., Schmid, U., Goeldner, R. G., Strelkowa, N., Huang, D. C. L. 及其他3, Bogenrieder, T., Twelves, C. & Cheng, A. L., 四月 28 2020, 於 : British Journal of Cancer. 122, 9, p. 1324-1332 9 p.

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Upregulation of protein synthesis and proteasome degradation confers sensitivity to proteasome inhibitor bortezomib in myc-atypical teratoid/rhabdoid tumors

Tran, H. M., Wu, K. S., Sung, S. Y., Changou, C. A., Hsieh, T. H., Liu, Y. R., Liu, Y. L., Tsai, M. L., Lee, H. L., Hsieh, K. L. C., Huang, W. C., Liang, M. L., Chen, H. H., Lee, Y. Y., Lin, S. C., Ho, D. M. T., Chang, F. C., Chao, M. E., Chen, W., Chu, S. S. 及其他4, Yu, A. L., Yen, Y., Chang, C. C. & Wong, T. T., 三月 22 2020, 於 : Cancers. 12, 3, 752.

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2019
6 引文 斯高帕斯(Scopus)

Action of Reverse T3 on Cancer Cells

Lin, H. Y., Tang, H. Y., Leinung, M., Mousa, S. A., Hercbergs, A. & Davis, P. J., 一月 1 2019, 於 : Endocrine Research.

研究成果: 雜誌貢獻文章

3 引文 斯高帕斯(Scopus)

Alternative splicing in human cancer cells is modulated by the amiloride derivative 3,5-diamino-6-chloro-N-(N-(2,6-dichlorobenzoyl)carbamimidoyl)pyrazine-2-carboxide

Lee, C. C., Chang, W. H., Chang, Y. S., Yang, J. M., Chang, C. S., Hsu, K. C., Chen, Y. T., Liu, T. Y., Chen, Y. C., Lin, S. Y., Wu, Y. C. & Chang, J. G., 一月 1 2019, 於 : Molecular Oncology. 13, 8, p. 1744-1762 19 p.

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2 引文 斯高帕斯(Scopus)

Androgen deprivation-induced ZBTB46-PTGS1 signaling promotes neuroendocrine differentiation of prostate cancer

Chen, W. Y., Zeng, T., Wen, Y. C., Yeh, H. L., Jiang, K. C., Chen, W. H., Zhang, Q., Huang, J. & Liu, Y. N., 一月 1 2019, 於 : Cancer Letters. 440-441, p. 35-46 12 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)
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2 引文 斯高帕斯(Scopus)
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2 引文 斯高帕斯(Scopus)

Anti-metastatic activity of MPT0G211, a novel HDAC6 inhibitor, in human breast cancer cells in vitro and in vivo

Hsieh, Y. L., Tu, H. J., Pan, S. L., Liou, J. P. & Yang, C. R., 六月 1 2019, 於 : Biochimica et Biophysica Acta - Molecular Cell Research. 1866, 6, p. 992-1003 12 p.

研究成果: 雜誌貢獻文章

7 引文 斯高帕斯(Scopus)

Association of matrix Metalloproteinase-9 rs3918242 promoter genotypes with colorectal cancer risk

Wu, M. H., Tzeng, H. E., Wu, C. N., Yueh, T. C., Peng, Y. C., Tsai, C. H., Wang, Y. C., Ke, T. W., Pei, J. S., Chang, W. S., Tsai, C. W. & Bau, D. T., 一月 1 2019, 於 : Anticancer Research. 39, 12, p. 6523-6529 7 p.

研究成果: 雜誌貢獻文章

4 引文 斯高帕斯(Scopus)

Chicken-Derived Humanized Antibody Targeting a Novel Epitope F2pep of Fibroblast Growth Factor Receptor 2: Potential Cancer Therapeutic Agent

Tsai, K. C., Chang, C. D., Cheng, M. H., Lin, T. Y., Lo, Y. N., Yang, T. W., Chang, F. L., Chiang, C. W., Lee, Y. C. & Yen, Y., 一月 31 2019, 於 : ACS Omega. 4, 1, p. 2387-2397 11 p.

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1 引文 斯高帕斯(Scopus)