生藥學研究所

2016

Anti-cancer activity of Solanum nigrum (AESN) through suppression of mitochondrial function and epithelial-mesenchymal transition (EMT) in breast cancer cells

Lai, Y. J., Tai, C. J., Wang, C. W., Choong, C. Y., Lee, B. H., Shi, Y. C. & Tai, C. J., 5月 1 2016, 於: Molecules. 21, 5, 553.

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40 引文斯高帕斯（Scopus）

Anti-inflammatory and Antinociceptive Constituents of Atractylodes japonica Koidzumi

Chen, L. G., Jan, Y. S., Tsai, P. W., Norimoto, H., Michihara, S., Murayama, C. & Wang, C. C., 3月 23 2016, 於: Journal of Agricultural and Food Chemistry. 64, 11, p. 2254-2262 9 p.

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56 引文斯高帕斯（Scopus）

Anti-MMP-2 Activity and Skin-Penetrating Capability of the Chemical Constituents from Rhodiola rosea

Lee, T-H., Hsu, C. C., Hsiao, G., Fang, J. Y., Liu, W. M. & Lee, C. K., 5月 1 2016, 於: Planta Medica. 82, 8, p. 698-704

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9 引文斯高帕斯（Scopus）

Antinociceptive and anti-inflammatory effects of zerumbone against mono-iodoacetate-induced arthritis

Chien, T. Y., Huang, S. K. H., Lee, C. J., Tsai, P. W. & Wang, C. C., 2月 1 2016, 於: International Journal of Molecular Sciences. 17, 2, 249.

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28 引文斯高帕斯（Scopus）

Antiobesity and antihyperlipidaemic effects of Yan-Sheng-Yin in animals and humans

Wu, C. H., Pan, C. H., Lee, C. K., Sheu, M. J., Liu, F. C., Wang, G. J. & Wu, C. H., 6月 1 2016, 於: Journal of Functional Foods. 24, p. 173-182 10 p.

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1 引文斯高帕斯（Scopus）

Application of propensity scores to estimate the association between cardiovascular disease and meridian energy

Chen, P. H., Tai, C. J., Chien, L. Y., Lai, J. C. Y., Huang, S. M. & Chen, Y. H., 2016, 於: European Journal of Integrative Medicine.

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3 引文斯高帕斯（Scopus）

Aqueous extract of Paris polyphylla (AEPP) inhibits ovarian cancer via suppression of peroxisome proliferator-activated receptor-gamma coactivator (PGC)-1alpha

Wang, C. W., Tai, C. J., Choong, C. Y., Lin, Y. C., Lee, B. H., Shi, Y. C. & Tai, C. J., 6月 1 2016, 於: Molecules. 21, 6, 727.

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20 引文斯高帕斯（Scopus）

Changes in urinary Cu, Zn, and Se levels in cancer patients after treatment with Sha Shen Mai Men Dong Tang

Lai, T-I. & Kuo, H. W., 4月 1 2016, 於: Journal of Traditional and Complementary Medicine. 6, 2, p. 135-139 5 p.

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3 引文斯高帕斯（Scopus）

Chemical Constituents from Termite-associated Xylaria acuminatilongissima YMJ623

Cho, T. Y., Wang, G. J., Ju, Y. M., Chen, M. C. & Lee, T. H., 5月 1 2016, 於: Journal of the Chinese Chemical Society. 63, 5, p. 404-409 6 p.

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4 引文斯高帕斯（Scopus）

Codelivery of doxorubicin-containing thermosensitive hydrogels incorporated with docetaxel-loaded mixed micelles enhances local cancer therapy

Sheu, M. T., Jhan, H. J., Su, C. Y., Chen, L. C., Chang, C. E., Liu, D. Z. & Ho, H. O., 7月 1 2016, 於: Colloids and Surfaces B: Biointerfaces. 143, p. 260-270 11 p.

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45 引文斯高帕斯（Scopus）

Combination of the novel histone deacetylase inhibitor YCW1 and radiation induces autophagic cell death through the downregulation of BNIP3 in triple-negative breast cancer cells in vitro and in an orthotopic mouse model

Chiu, H. W., Yeh, Y. L., Wang, Y. C., Huang, W. J., Ho, S. Y., Lin, P. & Wang, Y. J., 6月 10 2016, 於: Molecular Cancer. 15, 1, 46.

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30 引文斯高帕斯（Scopus）

Combination of Two Targeted Medications (Bevacizumab Plus Cetuximab) Improve the Therapeutic Response of Pancreatic Carcinoma

Tai, C. J., Huang, M. T., Wu, C. H., Wang, C. K., Tai, C. J., Chang, C. C., Hsieh, C. I., Chang, Y. J., Wu, C. J., Kuo, L. J., Wei, P. L., Chen, R. J. & Chiou, H. Y., 4月 1 2016, 於: Medicine (United States). 95, 15, e3259.

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12 引文斯高帕斯（Scopus）

Development and Characterization of Lecithin-based Self-assembling Mixed Polymeric Micellar (saMPMs) Drug Delivery Systems for Curcumin

Chen, L. C., Chen, Y-C., Su, C. Y., Wong, W. P., Sheu, M-T. & Ho, H-O., 11月 16 2016, 於: Scientific Reports. 6, 37122.

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30 引文斯高帕斯（Scopus）

Development and characterization of self-assembling lecithin-based mixed polymeric micelles containing quercetin in cancer treatment and an in vivo pharmacokinetic study

Chen, L. C., Chen, Y. C., Su, C. Y., Hong, C. S., Ho, H. O. & Sheu, M. T., 4月 15 2016, 於: International Journal of Nanomedicine. 11, p. 1557-1566 10 p.

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35 引文斯高帕斯（Scopus）

Direct electrical stimulation on the injured ulnar nerve using acupuncture needles combined with rehabilitation accelerates nerve regeneration and functional recovery-A case report

Tang, Y. J., Wu, M. H. & Tai, C. J., 2月 1 2016, 於: Complementary Therapies in Medicine. 24, p. 103-107 5 p.

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5 引文斯高帕斯（Scopus）

Effects of Dang-Gui-Bu-Xue-Tang, an herbal decoction, on iron uptake in iron-deficient anemia

Huang, G. C., Chen, S. Y., Tsai, P. W., Ganzon, J. G., Lee, C. J., Shiah, H. S. & Wang, C. C., 3月 2 2016, 於: Drug Design, Development and Therapy. 10, p. 949-957 9 p.

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13 引文斯高帕斯（Scopus）

Effects of different forages on the chemical compositions and antiosteoporotic activities of velvet antlers

Tseng, S. H., Chen, L. G., Lai, Y. J., Wang, K. T. & Wang, C. C., 8月 1 2016, 於: Animal science journal = Nihon chikusan Gakkaiho. 87, 8, p. 989-996 8 p.

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4 引文斯高帕斯（Scopus）

Effects of non-sporting and sporting qigong on frailty and quality of life among breast cancer patients receiving chemotherapy

Huang, S. M., Tseng, L. M., Chien, L. Y., Tai, C. J., Chen, P. H., Hung, C. T. & Hsiung, Y., 4月 1 2016, 於: European Journal of Oncology Nursing. 21, p. 257-265 9 p.

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8 引文斯高帕斯（Scopus）

Engineering Chimeric Receptors To Investigate the Size- and Rigidity-Dependent Interaction of PEGylated Nanoparticles with Cells

Huang, W-C., Burnouf, P-A., Su, Y-C., Chen, B-M., Chuang, K-H., Lee, C-W., Wei, P-K., Cheng, T-L. & Roffler, S. R., 1月 13 2016, 於: ACS Nano. 10, 1, p. 648-62 15 p.

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23 引文斯高帕斯（Scopus）

Hispidulin alleviated methamphetamine-induced hyperlocomotion by acting at α6 subunit-containing GABA_A receptors in the cerebellum

Liao, Y. H., Lee, H. J., Huang, W. J., Fan, P. C. & Chiou, L. C., 9月 1 2016, 於: Psychopharmacology. 233, 17, p. 3187-3199 13 p.

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14 引文斯高帕斯（Scopus）

Imperatorin exerts antiallergic effects in Th2-mediated allergic asthma via induction of IL-10-producing regulatory T cells by modulating the function of dendritic cells

Lin, C. L., Hsiao, G., Wang, C. C. & Lee, Y. L., 8月 1 2016, 於: Pharmacological Research. 110, p. 111-121 11 p.

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27 引文斯高帕斯（Scopus）

Improving the stability of astaxanthin by microencapsulation in calcium alginate beads

Lin, S. F., Chen, Y. C., Chen, R. N., Chen, L. C., Ho, H. O., Tsung, Y. H., Sheu, M. T. & Liu, D. Z., 4月 1 2016, 於: PLoS One. 11, 4, e0153685.

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35 引文斯高帕斯（Scopus）

Inhibition of HDAC3- and HDAC6-promoted survivin expression plays an important role in SAHA-induced autophagy and viability reduction in breast cancer cells

Lee, J. Y. C., Kuo, C. W., Tsai, S. L., Cheng, S. M., Chen, S. H., Chan, H. H., Lin, C. H., Lin, K. Y., Li, C. F., Kanwar, J. R., Leung, E. Y., Cheung, C. C. H., Huang, W. J., Wang, Y. C. & Cheung, C. H. A., 3月 31 2016, 於: Frontiers in Pharmacology. 7, MAR, 81.

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39 引文斯高帕斯（Scopus）

LTP-1, a novel antimitotic agent and Stat3 inhibitor, inhibits human pancreatic carcinomas in vitro and in vivo

Huang, H. L., Chao, M. W., Chen, C. C., Cheng, C. C., Chen, M. C., Lin, C. F., Liou, J. P., Teng, C. M. & Pan, S. L., 6月 9 2016, 於: Scientific Reports. 6, 27794.

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8 引文斯高帕斯（Scopus）

Measurement of Pre-Existing IgG and IgM Antibodies against Polyethylene Glycol in Healthy Individuals

Chen, B. M., Su, Y. C., Chang, C. J., Burnouf, P. A., Chuang, K-H., Chen, C. H., Cheng, T. L., Chen, Y. T., Wu, J. Y. & Roffler, S. R., 11月 1 2016, 於: Analytical Chemistry. 88, 21, p. 10661-10666 6 p.

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75 引文斯高帕斯（Scopus）

Methyl Protodioscin, a Steroidal Saponin, Inhibits Neointima Formation in Vitro and in Vivo

Chung, Y. L., Pan, C. H., Wang, C. C. N., Hsu, K. C., Sheu, M. J., Chen, H. F. & Wu, C. H., 6月 24 2016, 於: Journal of Natural Products. 79, 6, p. 1635-1644 10 p.

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9 引文斯高帕斯（Scopus）

MPT0G066, a novel anti-mitotic drug, induces JNK-independent mitotic arrest, JNK-mediated apoptosis, and potentiates antineoplastic effect of cisplatin in ovarian cancer

Huang, H. L., Chao, M. W., Li, Y. C., Chang, L. H., Chen, C-H., Chen, M. C., Cheng, C. C., Liou, J. P., Teng, C. M. & Pan, S. L., 8月 16 2016, 於: Scientific Reports. 6, 31664.

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12 引文斯高帕斯（Scopus）

Neuroprotective effect of docosahexaenoic acid nanoemulsion on erectile function in a rat model of bilateral cavernous nerve injury

Liao, C. H., Wu, Y. N., Chen, B. H., Lin, Y. H., Ho, H. O. & Chiang, H-S., 9月 14 2016, 於: Scientific Reports. 6, 33040.

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8 引文斯高帕斯（Scopus）

Novel histone deacetylase inhibitor MPT0G009 induces cell apoptosis and synergistic anticancer activity with tumor necrosis factor-related apoptosis-inducing ligand against human hepatocellular carcinoma

Chen, M-C., Huang, H-H., Lai, C-Y., Lin, Y-J., Liou, J-P., Lai, M-J., Li, Y-H., Teng, C-M. & Yang, C-R., 1月 5 2016, 於: Oncotarget. 7, 1, p. 402-17 16 p.

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20 引文斯高帕斯（Scopus）

Optimization of an Anti-poly(ethylene glycol) (anti-PEG) Cell-Based Capture System To Quantify PEG and PEGylated Molecules

Lin, W. W., Hsieh, Y. C., Cheng, Y-A., Chuang, K-H., Huang, C. C., Chuang, C. H., Chen, I. J., Cheng, K. W., Lu, Y-C., Cheng, T. C., Wang, Y. T., Roffler, S. R. & Cheng, T. L., 12月 20 2016, 於: Analytical Chemistry. 88, 24, p. 12371-12379 9 p.

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11 引文斯高帕斯（Scopus）

Optimization of platelet-rich plasma and its effects on the recovery of erectile function after bilateral cavernous nerve injury in a rat model

Wu, Y. N., Wu, C. C., Sheu, M. T., Chen, K. C., Ho, H. O. & Chiang, H. S., 10月 1 2016, 於: Journal of Tissue Engineering and Regenerative Medicine. 10, 10, p. E294-E304

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44 引文斯高帕斯（Scopus）

Polyhydroxycurcuminoids but not curcumin upregulate neprilysin and can be applied to the prevention of Alzheimer's disease

Chen, P. T., Chen, Z. T., Hou, W. C., Yu, L. C. & Chen, R. P. Y., 7月 13 2016, 於: Scientific Reports. 6, 29760.

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30 引文斯高帕斯（Scopus）

Rapid-Onset Sildenafil Sublingual Drug Delivery Systems: In Vitro Evaluation and In Vivo Pharmacokinetic Studies in Rabbits

Sheu, M. T., Hsieh, C. M., Chen, R. N., Chou, P. Y. & Ho, H. O., 9月 1 2016, 於: Journal of Pharmaceutical Sciences. 105, 9, p. 2774-2781 8 p.

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13 引文斯高帕斯（Scopus）

Solanum nigrum protects against hepatic fibrosis via suppression of hyperglycemia in high-fat/ethanol diet-induced rats

Tai, C. J., Choong, C. Y., Shi, Y. C., Lin, Y. C., Wang, C-W., Lee, B. H. & Tai, C. J., 3月 1 2016, 於: Molecules. 21, 3, 269.

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16 引文斯高帕斯（Scopus）

Synthesis and biological evaluation of lovastatin-derived aliphatic hydroxamates that induce reactive oxygen species

Lin, R. K., Lin, Y. F., Hsu, M. J., Hsieh, C. L., Wang, C. Y., Huang, C. C. & Huang, W. J., 2016, 於: Bioorganic and Medicinal Chemistry Letters. 26, 22, p. 5528-5533 6 p.

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3 引文斯高帕斯（Scopus）

Synthesized Peptides from Yam Dioscorin Hydrolysis in Silico Exhibit Dipeptidyl Peptidase-IV Inhibitory Activities and Oral Glucose Tolerance Improvements in Normal Mice

Lin, Y. S., Han, C. H., Lin, S. Y. & Hou, W. C., 8月 24 2016, 於: Journal of Agricultural and Food Chemistry. 64, 33, p. 6451-6458 8 p.

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12 引文斯高帕斯（Scopus）

Terpenoids from the fermented broths of coprinellus radians

Lee, M. S., Hsiao, C. J., Ju, Y. M., Kuo, Y. H., Lin, R. K. & Lee, T. H., 9月 2016, 於: Natural Product Communications. 11, 9, p. 1229-1230 2 p.

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2 引文斯高帕斯（Scopus）

The anti-hepatic fibrosis activity of ergosterol depended on upregulation of PPARgamma in HSC-T6 cells

Tai, C. J., Choong, C. Y., Lin, Y. C., Shi, Y. C. & Tai, C. J., 4月 1 2016, 於: Food and Function. 7, 4, p. 1915-1923 9 p.

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10 引文斯高帕斯（Scopus）

The clinical and biochemical characteristics associated with insulin resistance in non-obese young women

Wang, C. C., Chang, C. J. & Hsu, M. I., 2016, 於: Gynecological Endocrinology. 32, 9, p. 767-771 5 p.

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1 引文斯高帕斯（Scopus）

Thrombomodulin influences the survival of patients with non-metastatic colorectal cancer through epithelial-to-mesenchymal transition (EMT)

Chang, Y. J., Cheng, Y. W., Lin, R. K., Huang, C. C., Chen, W. T. L., Ke, T. W. & Wei, P. L., 8月 2016, 於: PLoS ONE. 11, 8, e0160550.

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10 引文斯高帕斯（Scopus）

Using anti-poly(ethylene glycol) bioparticles for the quantitation of PEGylated nanoparticles

Hsieh, Y. C., Cheng, T. C., Wang, H. E., Li, J. J., Lin, W. W., Huang, C. C., Chuang, C. H., Wang, Y. T., Wang, J. Y., Roffler, S. R., Chuang, K-H. & Cheng, T. L., 12月 19 2016, 於: Scientific Reports. 6, 39119.

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6 引文斯高帕斯（Scopus）

2015

Anti-inflammatory effects of platelet biomaterials in a macrophage cellular model

Renn, T. Y., Kao, Y. H., Wang, C. C. & Burnouf, T., 8月 1 2015, 於: Vox Sanguinis. 109, 2, p. 138-147 10 p.

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23 引文斯高帕斯（Scopus）

Anti-restenotic roles of dihydroaustrasulfone alcohol involved in inhibiting PDGF-BB-stimulated proliferation and migration of vascular smooth muscle cells

Li, P. C., Sheu, M. J., Ma, W. F., Pan, C. H., Sheu, J. H. & Wu, C. H., 5月 1 2015, 於: Marine Drugs. 13, 5, p. 3046-3060 15 p.

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17 引文斯高帕斯（Scopus）

Anti-α-glucosidase and Anti-dipeptidyl Peptidase-IV Activities of Extracts and Purified Compounds from Vitis thunbergii var. taiwaniana

Lin, Y. S., Chen, C. R., Wu, W. H., Wen, C. L., Chang, C. I. & Hou, W. C., 7月 22 2015, 於: Journal of Agricultural and Food Chemistry. 63, 28, p. 6393-6401 9 p.

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27 引文斯高帕斯（Scopus）

A population-based nested case-control study: The use of 5-alpha-reductase inhibitors and the increased risk of osteoporosis diagnosis in patients with benign prostate hyperplasia

Lin, W. L., Hsieh, Y. W., Lin, C. L., Sung, F. C., Wu, C. H. & Kao, C. H., 4月 1 2015, 於: Clinical Endocrinology. 82, 4, p. 503-508 6 p.

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22 引文斯高帕斯（Scopus）

Application of photoluminescent bioceramic material for different chronic illnesses by selecting "trigger points" and "propagated sensation along meridians" phenomenon

Leung, T-K., Gasbarri, M., Tai, C-J. & Chan, W. P., 7月 4 2015, 於: Chinese Journal of Integrative Medicine.

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Bioceramic Resonance Effect on Meridian Channels: A Pilot Study

Leung, T-K., Chan, W. P., Tai, C. J., Cho, T. P., Yang, J. C. & Lee, P. T., 2015, 於: Evidence-based Complementary and Alternative Medicine. 2015, 769546.

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9 引文斯高帕斯（Scopus）

Caesarean delivery before 39 weeks associated with selecting an auspicious time for birth in Taiwan

Chu, K. H., Lee, Y. H., Tai, C. J., Lin, Y. H., Huang, C. M. & Chien, L. Y., 9月 1 2015, 於: Women and Birth. 28, 3, p. e52-e56

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6 引文斯高帕斯（Scopus）

Chemical constituents analysis and antidiabetic activity validation of four fern species from Taiwan

Chen, C. Y., Chiu, F. Y., Lin, Y., Huang, W. J., Hsieh, P. S. & Hsu, F-L., 1月 22 2015, 於: International journal of molecular sciences. 16, 2, p. 2497-2516 20 p.

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10 引文斯高帕斯（Scopus）

Cisplatin-, Doxorubicin-, and Docetaxel-Induced Cell Death Promoted by the Aqueous Extract of Solanum nigrum in Human Ovarian Carcinoma Cells

Tai, C. J., Wang, C-W., Chen, C. L., Wang, C. K., Chang, Y. J., Jian, J. Y., Lin, C. S. & Tai, C. J., 11月 1 2015, 於: Integrative Cancer Therapies. 14, 6, p. 546-555 10 p.

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19 引文斯高帕斯（Scopus）

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