生藥學研究所

文章

New constituents from the heartwood of Picea morrisonicola HAYATA

Li, Z-H., Yeh, M. H., Chang, C. I., Lee, C. K., Shao, Y. Y. & Kuo, Y. H., 2006, 於: Chemical and Pharmaceutical Bulletin. 54, 5, p. 693-695 3 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

8 引文斯高帕斯（Scopus）

New constituents with iNOS inhibitory activity from mycelium of Antrodia camphorata

Yang, S. S., Wang, G. J., Wang, S. Y., Lin, Y. Y., Kuo, Y. H. & Li, Z-H., 4月 2009, 於: Planta Medica. 75, 5, p. 512-516 5 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

51 引文斯高帕斯（Scopus）

New coumarins and anti-inflammatory constituents from Zanthoxylum avicennae

Cho, J. Y., Hwang, T. L., Chang, T. H., Lim, Y. P., Sung, P. J., Li, Z-H. & Chen, J. J., 11月 1 2012, 於: Food Chemistry. 135, 1, p. 17-23 7 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

43 引文斯高帕斯（Scopus）

New ent-kaurene and germacrene derivatives from Mesona procumbens Hemseley and their biological activity

Ganzon, J. G., Liaw, C. C., Lin, Y. C., Lin, Z. H., Wang, C. H., Chen, C. Y., Chuang, K. H. & Kuo, Y. H., 2022, (接受/付印) 於: Natural Product Research.

研究成果: 雜誌貢獻 › 文章 › 同行評審

1 引文斯高帕斯（Scopus）

New Hirsutinolide-Type Sesquiterpenoids from Vernonia cinerea Inhibit Nitric Oxide Production in LPS-Stimulated RAW264.7 Cells

Kuo, L. M. Y., Tseng, P. Y., Lin, Y. C., Liaw, C. C., Zhang, L. J., Tsai, K. C., Lin, Z. H., Ho, H. O. & Kuo, Y. H., 7月 9 2018, 於: Planta Medica. 84, 18, p. 1348-1354 7 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

5 引文斯高帕斯（Scopus）

New isoflavones and anti-inflammatory constituents from the fruits of Cnidium monnieri

Li, Z-H., Chen, Y. C., Hwang, T. L., Shu, C. W., Sung, P. J., Lim, Y. P., Kuo, W. L. & Chen, J. J., 3月 28 2014, 於: International Journal of Molecular Sciences. 15, 6, p. 9566-9578 13 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

12 引文斯高帕斯（Scopus）

New lignans from the heartwood of Cunninghamia lanceolata

Li, Z-H., Yeh, M. H., Chang, C. I., Lee, C. K., Shao, Y. Y. & Kuo, Y. H., 2007, 於: Bioscience, Biotechnology and Biochemistry. 71, 8, p. 2075-2078 4 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

10 引文斯高帕斯（Scopus）

New prenylated flavones from the roots of Ficus beecheyana

Lee, C. K., Lu, C. K., Kuo, Y. H., Chen, J. Z. & Sun, G. Z., 4月 2004, 於: Journal of the Chinese Chemical Society. 51, 2, p. 437-441 5 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

50 引文斯高帕斯（Scopus）

New terpenoids from Chamaecyparis formosensis (Cupressaceae) leaves with modulatory activity on matrix metalloproteases 2 and 9

Chang, M. L., Mei, H. C., Kuo, I. C., Hsiao, G., Kuo, Y. H. & Lee, C. K., 3月 7 2018, 於: Molecules. 23, 3, 604.

研究成果: 雜誌貢獻 › 文章 › 同行評審

1 引文斯高帕斯（Scopus）

New whitening constituents from taiwan-native Pyracantha koidzumii: Structures and tyrosinase inhibitory analysis in human epidermalmelanocytes

Lin, R. D., Chen, M. C., Liu, Y. L., Lin, Y. T., Lu, M. K., Hsu, F-L. & Lee, M. H., 12月 2 2015, 於: International Journal of Molecular Sciences. 16, 12, p. 28598-28613 16 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

15 引文斯高帕斯（Scopus）

N-hydroxycinnamide derivatives of osthole ameliorate hyperglycemia through activation of AMPK and p38 MAPK

Lee, W. H., Wu, H. H., Huang, W. J., Li, Y. N., Lin, R-J., Lin, S. Y. & Liang, Y. C., 3月 1 2015, 於: Molecules. 20, 3, p. 4516-4529 14 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

10 引文斯高帕斯（Scopus）

N-hydroxycinnamide derivatives of osthole inhibit cell migration and invasion by suppressing smad2 and akt pathways in human colorectal adenocarcinoma cells

Liu, L. Y., Huang, W. J., Ho, F. M., Lin, R-J., Lin, S. Y., Suk, F. M. & Liang, Y. C., 6月 25 2014, 於: Chemico-Biological Interactions. 217, p. 1-8 8 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

13 引文斯高帕斯（Scopus）

N -hydroxycinnamide derivatives of osthole presenting genotoxicity and cytotoxicity against human colon adenocarcinoma cells in vitro and in vivo

Liu, L. Y., Huang, W. J., Lin, R-J., Lin, S. Y. & Liang, Y. C., 11月 18 2013, 於: Chemical Research in Toxicology. 26, 11, p. 1683-1691 9 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

13 引文斯高帕斯（Scopus）

Nicotinic acid hydroxamate downregulated the melanin synthesis and tyrosinase activity through activating the MEK/ERK and AKT/GSK3β signaling pathways

Lin, Y. S., Chuang, M. T., Chen, C. H., Chien, M. Y. & Hou, W. C., 5月 16 2012, 於: Journal of Agricultural and Food Chemistry. 60, 19, p. 4859-4864 6 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

24 引文斯高帕斯（Scopus）

Novel application of pluronic lecithin organogels (PLOs) for local delivery of synergistic combination of docetaxel and cisplatin to improve therapeutic efficacy against ovarian cancer

Chang, C. E., Hsieh, C. M., Chen, L. C., Su, C. Y., Liu, D. Z., Jhan, H. J., Ho, H. O. & Sheu, M. T., 1月 1 2018, 於: Drug Delivery. 25, 1, p. 632-643 12 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

19 引文斯高帕斯（Scopus）

Novel Class IIa-Selective Histone Deacetylase Inhibitors Discovered Using an in Silico Virtual Screening Approach

Hsu, K. C., Liu, C. Y., Lin, T. E., Hsieh, J. H., Sung, T. Y., Tseng, H. J., Yang, J. M. & Huang, W. J., 12月 1 2017, 於: Scientific Reports. 7, 1, 3228.

研究成果: 雜誌貢獻 › 文章 › 同行評審

32 引文斯高帕斯（Scopus）

Novel design of osmotic chitosan capsules characterized by asymmetric membrane structure for in situ formation of delivery orifice

Wang, G. M., Chen, C. H., Ho, H. O., Wang, S. S. & Sheu, M. T., 8月 17 2006, 於: International Journal of Pharmaceutics. 319, 1-2, p. 71-81 11 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

11 引文斯高帕斯（Scopus）

Novel ent-beyeran-19-oic acids from biotransformations of isosteviol metabolites by Mortierella isabellina

Lin, C. L., Lin, S. J., Huang, W. J., Ku, Y. L., Tsai, T. H. & Hsu, F-L., 12月 2007, 於: Planta Medica. 73, 15, p. 1581-1587 7 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

10 引文斯高帕斯（Scopus）

Novel histone deacetylase inhibitor MPT0G009 induces cell apoptosis and synergistic anticancer activity with tumor necrosis factor-related apoptosis-inducing ligand against human hepatocellular carcinoma

Chen, M-C., Huang, H-H., Lai, C-Y., Lin, Y-J., Liou, J-P., Lai, M-J., Li, Y-H., Teng, C-M. & Yang, C-R., 1月 5 2016, 於: Oncotarget. 7, 1, p. 402-17 16 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

19 引文斯高帕斯（Scopus）

Novel injectable thermosensitive hydrogels for delivering hyaluronic acid-doxorubicin nanocomplexes to locally treat tumors

Jhan, H. J., Liu, J. J., Chen, Y. C., Liu, D. Z., Sheu, M. T. & Ho, H. O., 4月 1 2015, 於: Nanomedicine. 10, 8, p. 1263-1274 12 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

25 引文斯高帕斯（Scopus）

Novel terpenoids from Calocedrus macrolepis var. formosana

Hsieh, C. L., Tseng, M. H., Pan, R. N., Chang, J. Y., Kuo, C. C., Li, Z-H. & Kuo, Y. H., 10月 2011, 於: Chemistry and Biodiversity. 8, 10, p. 1901-1907 7 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

8 引文斯高帕斯（Scopus）

Novel Two-Step Process in Cellulose Depolymerization: Hematite-Mediated Photocatalysis by Lytic Polysaccharide Monooxygenase and Fenton Reaction

Wang, D., Kao, M-R., Li, J., Sun, P., Meng, Q., Vyas, A., Liang, P-H., Wang, Y-S. & Hsieh, Y. S. Y., 8月 17 2022, 於: Journal of Agricultural and Food Chemistry. 70, 32, p. 9941-9947 7 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

1 引文斯高帕斯（Scopus）

NPRL-Z-1, as a new topoisomerase II poison, induces cell apoptosis and ROS generation in human renal carcinoma cells

Wu, S. Y., Pan, S. L., Xiao, Z. Y., Hsu, J. L., Chen, M. C., Lee, K. H. & Teng, C. M., 11月 5 2014, 於: PLoS ONE. 9, 11, e112220.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

12 引文斯高帕斯（Scopus）

NSC746364, a G-quadruplex-stabilizing agent, suppresses cell growth of A549 human lung cancer cells through activation of the ATR/Chk1-dependent pathway

Chung, Y. L., Pan, C. H., Liou, W. H., Sheu, M. J., Lin, W. H., Chen, T. C., Huang, H. S. & Wu, C. H., 2014, 於: Journal of Pharmacological Sciences. 124, 1, p. 7-17 11 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

11 引文斯高帕斯（Scopus）

N-Sulfonyl-aminobiaryls as Antitubulin Agents and Inhibitors of Signal Transducers and Activators of Transcription 3 (STAT3) Signaling

Lai, M-J., Lee, H. Y., Chuang, H-Y., Chang, L-H., Tsai, A-C., Chen, M. C., Huang, H-L., Wu, Y-W., Teng, C-M., Pan, S. L., Liu, Y-M., Mehndiratta, S. & Liou, J. P., 8月 27 2015, 於: Journal of Medicinal Chemistry. 58, 16, p. 6549-6558 10 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

24 引文斯高帕斯（Scopus）

Oct-4 induces cisplatin resistance and tumor stem cell-like properties in endometrial carcinoma cells

Lin, T. C., Wang, K. H., Chuang, K. H., Kao, A. P. & Kuo, T. C., 2022, (接受/付印) 於: Taiwanese Journal of Obstetrics and Gynecology.

研究成果: 雜誌貢獻 › 文章 › 同行評審

O-methylated flavonol as a multi-kinase inhibitor of leukemogenic kinases exhibits a potential treatment for acute myeloid leukemia

Yen, S. C., Wu, Y. W., Huang, C. C., Chao, M. W., Tu, H. J., Chen, L. C., Lin, T. E., Sung, T. Y., Tseng, H. J., Chu, J. C., Huang, W. J., Yang, C. R., HuangFu, W. C., Pan, S. L. & Hsu, K. C., 6月 2022, 於: Phytomedicine. 100, 154061.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

2 引文斯高帕斯（Scopus）

One-pot fabrication of sacchachitin for production of TEMPO-oxidized sacchachitin nanofibers (TOSCNFs) utilized as scaffolds to enhance bone regeneration

Wu, M. H., Wang, W., Chao, F. C., Hsieh, C. M., Chen, L. C., Lin, H. L., Ho, H. O., Huang, T. J. & Sheu, M. T., 2月 2021, 於: Carbohydrate Polymers. 254, 117270.

研究成果: 雜誌貢獻 › 文章 › 同行評審

2 引文斯高帕斯（Scopus）

One-step mixing with humanized anti-mPEG bispecific antibody enhances tumor accumulation and therapeutic efficacy of mPEGylated nanoparticles

Kao, C. H., Wang, J. Y., Chuang, K. H., Chuang, C. H., Cheng, T. C., Hsieh, Y. C., Tseng, Y. L., Chen, B. M., Roffler, S. R. & Cheng, T. L., 12月 1 2014, 於: Biomaterials. 35, 37, p. 9930-9940 11 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

39 引文斯高帕斯（Scopus）

Optimal conditions for cordycepin production in surface liquid-cultured Cordyceps militaris treated with porcine liver extracts for suppression of oral cancer

Lin, L. T., Lai, Y. J., Wu, S. C., Hsu, W. H. & Tai, C. J., 2月 2018, 於: Journal of Food and Drug Analysis. 26, 1, p. 135-144

研究成果: 雜誌貢獻 › 文章 › 同行評審

24 引文斯高帕斯（Scopus）

Optimal dose regimens of esomeprazole for gastric acid suppression with minimal influence of the CYP2C19 polymorphism

Lou, H. Y., Chang, C. C., Sheu, M. T., Chen, Y. C. & Ho, H. O., 1月 2009, 於: European Journal of Clinical Pharmacology. 65, 1, p. 55-64 10 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

42 引文斯高帕斯（Scopus）

Optimization of an Anti-poly(ethylene glycol) (anti-PEG) Cell-Based Capture System To Quantify PEG and PEGylated Molecules

Lin, W. W., Hsieh, Y. C., Cheng, Y-A., Chuang, K-H., Huang, C. C., Chuang, C. H., Chen, I. J., Cheng, K. W., Lu, Y-C., Cheng, T. C., Wang, Y. T., Roffler, S. R. & Cheng, T. L., 12月 20 2016, 於: Analytical Chemistry. 88, 24, p. 12371-12379 9 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

12 引文斯高帕斯（Scopus）

Optimization of platelet-rich plasma and its effects on the recovery of erectile function after bilateral cavernous nerve injury in a rat model

Wu, Y. N., Wu, C. C., Sheu, M. T., Chen, K. C., Ho, H. O. & Chiang, H. S., 10月 1 2016, 於: Journal of Tissue Engineering and Regenerative Medicine. 10, 10, p. E294-E304

研究成果: 雜誌貢獻 › 文章 › 同行評審

50 引文斯高帕斯（Scopus）

Osteoporosis increases subsequent risk of gallstone: A nationwide population-based cohort study in Taiwan

Klahan, S., Kuo, C. N., Chien, S-C., Lin, Y. W., Lin, C. Y., Lin, C. H., Chang, W. C., Lin, C. I., Hung, K. S. & Chang, W. P., 11月 18 2014, 於: BMC Gastroenterology. 14, 1, 192.

研究成果: 雜誌貢獻 › 文章 › 同行評審

4 引文斯高帕斯（Scopus）

Osthole and imperatorin, the active constituents of Cnidium monnieri (L.) Cusson, facilitate glutamate release from rat hippocampal nerve terminals

Wang, S. J., Lin, T. Y., Lu, C. W. & Huang, W. J., 12月 2008, 於: Neurochemistry International. 53, 6-8, p. 416-423 8 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

46 引文斯高帕斯（Scopus）

Osthole or imperatorin-mediated facilitation of glutamate release is associated with a synaptic vesicle mobilization in rat hippocampal glutamatergic nerve endings

Lin, T. Y., Lu, C. W., Huang, W. J. & Wang, S. J., 5月 2010, 於: Synapse. 64, 5, p. 390-396 7 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

12 引文斯高帕斯（Scopus）

Oxidative stress-induced cellular senescence desensitizes cell growth and migration of vascular smooth muscle cells through down-regulation of platelet-derived growth factor receptor-beta

Pan, C. H., Chen, C. J., Shih, C. M., Wang, M. F., Wang, J. Y. & Wu, C. H., 1月 1 2019, 於: Aging. 11, 19, p. 8085-8102 18 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

5 引文斯高帕斯（Scopus）

Pardaxin Promoted Differentiation and Maturation of Leukemic Cells via Regulating TLR2/MyD88 Signal against Cell Proliferation

Uen, W. C., Choong, C. Y., Tai, C. J. & Tai, C. J., 1月 1 2019, 於: Evidence-based Complementary and Alternative Medicine. 2019, 7035087.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

2 引文斯高帕斯（Scopus）

Paris polyphylla inhibits colorectal cancer cells via inducing autophagy and enhancing the efficacy of chemotherapeutic drug doxorubicin

Lin, L. T., Uen, W. C., Choong, C. Y., Shi, Y. C., Lee, B. H., Tai, C. J. & Tai, C. J., 6月 3 2019, 於: Molecules. 24, 11, 2102.

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

17 引文斯高帕斯（Scopus）

Patatin, the tuber storage protein of potato (Solanum tuberosum L.), exhibits antioxidant activity in vitro

Liu, Y. W., Han, C. H., Lee, M. H., Hsu, F-L. & Hou, W. C., 7月 16 2003, 於: Journal of Agricultural and Food Chemistry. 51, 15, p. 4389-4393 5 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

102 引文斯高帕斯（Scopus）

Pb²⁺ induces gastrin gene expression by extracellular signal-regulated kinases 1/2 and transcription factor activator protein 1 in human gastric carcinoma cells

Chan, C. P., Tsai, Y. T., Chen, Y. L., Hsu, Y. W., Tseng, J. T., Chuang, H. Y., Shiurba, R., Lee, M. H., Wang, J. Y. & Chang, W. C., 2月 1 2015, 於: Environmental Toxicology. 30, 2, p. 129-136 8 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

7 引文斯高帕斯（Scopus）

Pectin hydroxamic acids exhibit antioxidant activities in vitro

Yang, S. S., Cheng, K. T., Lin, Y. S., Liu, Y. W. & Hou, W. C., 6月 30 2004, 於: Journal of Agricultural and Food Chemistry. 52, 13, p. 4270-4273 4 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

35 引文斯高帕斯（Scopus）

Penetration enhancement by menthol combined with a solubilization effect in a mixed solvent system

Ho, H. O., Chen, L. C., Lin, H. M. & Sheu, M. T., 2月 12 1998, 於: Journal of Controlled Release. 51, 2-3, p. 301-311 11 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

45 引文斯高帕斯（Scopus）

Percutaneous penetration enhancement by menthol via solubilization effect in a mixed solvent system

Chen, L. C., Ho, H. O. & Sheu, M. T., 1997, 於: Proceedings of the Controlled Release Society. 24, p. 717-718 2 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

Pharmacokinetic Herb-Drug Interactions of Xiang-Sha-Liu-Jun-Zi-Tang and Paclitaxel in Male Sprague Dawley Rats and Its Influence on Enzyme Kinetics in Human Liver Microsomes

Kapelemera, A. M., Uang, Y-S., Wang, L-H., Wu, T-Y., Lee, F-Y., Tai, L., Wang, C-C. & Lee, C-J., 2022, 於: Frontiers in Pharmacology. 13

研究成果: 雜誌貢獻 › 文章 › 同行評審

1 引文斯高帕斯（Scopus）

Pharmacokinetics and tissue distribution of five major triterpenoids after oral administration of Rhizoma Alismatis extract to rats using ultra high-performance liquid chromatography–tandem mass spectrometry

Xu, W., Li, X., Lin, N., Zhang, X., Huang, X., Wu, T., Tai, Y., Chen, S., Wu, C. H., Huang, M. & Wu, S., 11月 30 2017, 於: Journal of Pharmaceutical and Biomedical Analysis. 146, p. 314-323 10 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

24 引文斯高帕斯（Scopus）

Pharmacokinetic study of paeoniflorin in mice after oral administration of Paeoniae radix extract

Chen, L. C., Lee, M. H., Chou, M. H., Lin, M. F. & Yang, L-L., 11月 26 1999, 於: Journal of Chromatography B: Biomedical Sciences and Applications. 735, 1, p. 33-40 8 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

43 引文斯高帕斯（Scopus）

Pharmacological effects of "Jutsu" (Atractylodis rhizome and Atractylodis lanceae rhizome) on 1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane (DOI)-Induced head twitch response in mice (I)

Murayama, C., Wang, C. C., Michihara, S. & Norimoto, H., 9月 18 2014, 於: Molecules. 19, 9, p. 14979-14986 8 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

6 引文斯高帕斯（Scopus）

Phase I Dose-Escalation Study of SCB01A, a Microtubule Inhibitor with Vascular Disrupting Activity, in Patients with Advanced Solid Tumors

Shiah, H. S., Chiang, N. J., Lin, C. C., Yen, C. J., Tsai, H. J., Wu, S. Y., Su, W. C., Chang, K. Y., Wang, C. C., Chang, J. Y. & Chen, L. T., 4月 2021, 於: Oncologist. 26, 4, p. e567-e579

研究成果: 雜誌貢獻 › 文章 › 同行評審

開啟存取

Phenolic constituents of Malus doumeri var. formosana in the field of skin care

Leu, S. J., Lin, Y. P., Lin, R. D., Wen, C. L., Cheng, K. T., Hsu, F-L. & Lee, M. H., 4月 2006, 於: Biological and Pharmaceutical Bulletin. 29, 4, p. 740-745 6 p.

研究成果: 雜誌貢獻 › 文章 › 同行評審

57 引文斯高帕斯（Scopus）

生藥學研究所

研究成果

搜尋結果