生藥學研究所

One-step mixing with humanized anti-mPEG bispecific antibody enhances tumor accumulation and therapeutic efficacy of mPEGylated nanoparticles

Kao, C. H., Wang, J. Y., Chuang, K. H., Chuang, C. H., Cheng, T. C., Hsieh, Y. C., Tseng, Y. L., Chen, B. M., Roffler, S. R. & Cheng, T. L., 12月 1 2014, 於: Biomaterials. 35, 37, p. 9930-9940 11 p.

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39 引文斯高帕斯（Scopus）

One-pot fabrication of sacchachitin for production of TEMPO-oxidized sacchachitin nanofibers (TOSCNFs) utilized as scaffolds to enhance bone regeneration

Wu, M. H., Wang, W., Chao, F. C., Hsieh, C. M., Chen, L. C., Lin, H. L., Ho, H. O., Huang, T. J. & Sheu, M. T., 2月 2021, 於: Carbohydrate Polymers. 254, 117270.

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2 引文斯高帕斯（Scopus）

O-methylated flavonol as a multi-kinase inhibitor of leukemogenic kinases exhibits a potential treatment for acute myeloid leukemia

Yen, S. C., Wu, Y. W., Huang, C. C., Chao, M. W., Tu, H. J., Chen, L. C., Lin, T. E., Sung, T. Y., Tseng, H. J., Chu, J. C., Huang, W. J., Yang, C. R., HuangFu, W. C., Pan, S. L. & Hsu, K. C., 6月 2022, 於: Phytomedicine. 100, 154061.

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2 引文斯高帕斯（Scopus）

Oct-4 induces cisplatin resistance and tumor stem cell-like properties in endometrial carcinoma cells

Lin, T. C., Wang, K. H., Chuang, K. H., Kao, A. P. & Kuo, T. C., 2022, (接受/付印) 於: Taiwanese Journal of Obstetrics and Gynecology.

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N-Sulfonyl-aminobiaryls as Antitubulin Agents and Inhibitors of Signal Transducers and Activators of Transcription 3 (STAT3) Signaling

Lai, M-J., Lee, H. Y., Chuang, H-Y., Chang, L-H., Tsai, A-C., Chen, M. C., Huang, H-L., Wu, Y-W., Teng, C-M., Pan, S. L., Liu, Y-M., Mehndiratta, S. & Liou, J. P., 8月 27 2015, 於: Journal of Medicinal Chemistry. 58, 16, p. 6549-6558 10 p.

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24 引文斯高帕斯（Scopus）

NSC746364, a G-quadruplex-stabilizing agent, suppresses cell growth of A549 human lung cancer cells through activation of the ATR/Chk1-dependent pathway

Chung, Y. L., Pan, C. H., Liou, W. H., Sheu, M. J., Lin, W. H., Chen, T. C., Huang, H. S. & Wu, C. H., 2014, 於: Journal of Pharmacological Sciences. 124, 1, p. 7-17 11 p.

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11 引文斯高帕斯（Scopus）

NPRL-Z-1, as a new topoisomerase II poison, induces cell apoptosis and ROS generation in human renal carcinoma cells

Wu, S. Y., Pan, S. L., Xiao, Z. Y., Hsu, J. L., Chen, M. C., Lee, K. H. & Teng, C. M., 11月 5 2014, 於: PLoS ONE. 9, 11, e112220.

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12 引文斯高帕斯（Scopus）

Novel Two-Step Process in Cellulose Depolymerization: Hematite-Mediated Photocatalysis by Lytic Polysaccharide Monooxygenase and Fenton Reaction

Wang, D., Kao, M-R., Li, J., Sun, P., Meng, Q., Vyas, A., Liang, P-H., Wang, Y-S. & Hsieh, Y. S. Y., 8月 17 2022, 於: Journal of Agricultural and Food Chemistry. 70, 32, p. 9941-9947 7 p.

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1 引文斯高帕斯（Scopus）

Novel terpenoids from Calocedrus macrolepis var. formosana

Hsieh, C. L., Tseng, M. H., Pan, R. N., Chang, J. Y., Kuo, C. C., Li, Z-H. & Kuo, Y. H., 10月 2011, 於: Chemistry and Biodiversity. 8, 10, p. 1901-1907 7 p.

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8 引文斯高帕斯（Scopus）

Novel injectable thermosensitive hydrogels for delivering hyaluronic acid-doxorubicin nanocomplexes to locally treat tumors

Jhan, H. J., Liu, J. J., Chen, Y. C., Liu, D. Z., Sheu, M. T. & Ho, H. O., 4月 1 2015, 於: Nanomedicine. 10, 8, p. 1263-1274 12 p.

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25 引文斯高帕斯（Scopus）

Novel histone deacetylase inhibitor MPT0G009 induces cell apoptosis and synergistic anticancer activity with tumor necrosis factor-related apoptosis-inducing ligand against human hepatocellular carcinoma

Chen, M-C., Huang, H-H., Lai, C-Y., Lin, Y-J., Liou, J-P., Lai, M-J., Li, Y-H., Teng, C-M. & Yang, C-R., 1月 5 2016, 於: Oncotarget. 7, 1, p. 402-17 16 p.

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19 引文斯高帕斯（Scopus）

Novel ent-beyeran-19-oic acids from biotransformations of isosteviol metabolites by Mortierella isabellina

Lin, C. L., Lin, S. J., Huang, W. J., Ku, Y. L., Tsai, T. H. & Hsu, F-L., 12月 2007, 於: Planta Medica. 73, 15, p. 1581-1587 7 p.

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10 引文斯高帕斯（Scopus）

Novel design of osmotic chitosan capsules characterized by asymmetric membrane structure for in situ formation of delivery orifice

Wang, G. M., Chen, C. H., Ho, H. O., Wang, S. S. & Sheu, M. T., 8月 17 2006, 於: International Journal of Pharmaceutics. 319, 1-2, p. 71-81 11 p.

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11 引文斯高帕斯（Scopus）

Novel Class IIa-Selective Histone Deacetylase Inhibitors Discovered Using an in Silico Virtual Screening Approach

Hsu, K. C., Liu, C. Y., Lin, T. E., Hsieh, J. H., Sung, T. Y., Tseng, H. J., Yang, J. M. & Huang, W. J., 12月 1 2017, 於: Scientific Reports. 7, 1, 3228.

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32 引文斯高帕斯（Scopus）

Novel application of pluronic lecithin organogels (PLOs) for local delivery of synergistic combination of docetaxel and cisplatin to improve therapeutic efficacy against ovarian cancer

Chang, C. E., Hsieh, C. M., Chen, L. C., Su, C. Y., Liu, D. Z., Jhan, H. J., Ho, H. O. & Sheu, M. T., 1月 1 2018, 於: Drug Delivery. 25, 1, p. 632-643 12 p.

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19 引文斯高帕斯（Scopus）

Nicotinic acid hydroxamate downregulated the melanin synthesis and tyrosinase activity through activating the MEK/ERK and AKT/GSK3β signaling pathways

Lin, Y. S., Chuang, M. T., Chen, C. H., Chien, M. Y. & Hou, W. C., 5月 16 2012, 於: Journal of Agricultural and Food Chemistry. 60, 19, p. 4859-4864 6 p.

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24 引文斯高帕斯（Scopus）

N -hydroxycinnamide derivatives of osthole presenting genotoxicity and cytotoxicity against human colon adenocarcinoma cells in vitro and in vivo

Liu, L. Y., Huang, W. J., Lin, R-J., Lin, S. Y. & Liang, Y. C., 11月 18 2013, 於: Chemical Research in Toxicology. 26, 11, p. 1683-1691 9 p.

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13 引文斯高帕斯（Scopus）

N-hydroxycinnamide derivatives of osthole inhibit cell migration and invasion by suppressing smad2 and akt pathways in human colorectal adenocarcinoma cells

Liu, L. Y., Huang, W. J., Ho, F. M., Lin, R-J., Lin, S. Y., Suk, F. M. & Liang, Y. C., 6月 25 2014, 於: Chemico-Biological Interactions. 217, p. 1-8 8 p.

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13 引文斯高帕斯（Scopus）

N-hydroxycinnamide derivatives of osthole ameliorate hyperglycemia through activation of AMPK and p38 MAPK

Lee, W. H., Wu, H. H., Huang, W. J., Li, Y. N., Lin, R-J., Lin, S. Y. & Liang, Y. C., 3月 1 2015, 於: Molecules. 20, 3, p. 4516-4529 14 p.

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10 引文斯高帕斯（Scopus）

New whitening constituents from taiwan-native Pyracantha koidzumii: Structures and tyrosinase inhibitory analysis in human epidermalmelanocytes

Lin, R. D., Chen, M. C., Liu, Y. L., Lin, Y. T., Lu, M. K., Hsu, F-L. & Lee, M. H., 12月 2 2015, 於: International Journal of Molecular Sciences. 16, 12, p. 28598-28613 16 p.

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15 引文斯高帕斯（Scopus）

New terpenoids from Chamaecyparis formosensis (Cupressaceae) leaves with modulatory activity on matrix metalloproteases 2 and 9

Chang, M. L., Mei, H. C., Kuo, I. C., Hsiao, G., Kuo, Y. H. & Lee, C. K., 3月 7 2018, 於: Molecules. 23, 3, 604.

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1 引文斯高帕斯（Scopus）

New prenylated flavones from the roots of Ficus beecheyana

Lee, C. K., Lu, C. K., Kuo, Y. H., Chen, J. Z. & Sun, G. Z., 4月 2004, 於: Journal of the Chinese Chemical Society. 51, 2, p. 437-441 5 p.

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50 引文斯高帕斯（Scopus）

New lignans from the heartwood of Cunninghamia lanceolata

Li, Z-H., Yeh, M. H., Chang, C. I., Lee, C. K., Shao, Y. Y. & Kuo, Y. H., 2007, 於: Bioscience, Biotechnology and Biochemistry. 71, 8, p. 2075-2078 4 p.

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10 引文斯高帕斯（Scopus）

New isoflavones and anti-inflammatory constituents from the fruits of Cnidium monnieri

Li, Z-H., Chen, Y. C., Hwang, T. L., Shu, C. W., Sung, P. J., Lim, Y. P., Kuo, W. L. & Chen, J. J., 3月 28 2014, 於: International Journal of Molecular Sciences. 15, 6, p. 9566-9578 13 p.

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12 引文斯高帕斯（Scopus）

New Hirsutinolide-Type Sesquiterpenoids from Vernonia cinerea Inhibit Nitric Oxide Production in LPS-Stimulated RAW264.7 Cells

Kuo, L. M. Y., Tseng, P. Y., Lin, Y. C., Liaw, C. C., Zhang, L. J., Tsai, K. C., Lin, Z. H., Ho, H. O. & Kuo, Y. H., 7月 9 2018, 於: Planta Medica. 84, 18, p. 1348-1354 7 p.

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5 引文斯高帕斯（Scopus）

New ent-kaurene and germacrene derivatives from Mesona procumbens Hemseley and their biological activity

Ganzon, J. G., Liaw, C. C., Lin, Y. C., Lin, Z. H., Wang, C. H., Chen, C. Y., Chuang, K. H. & Kuo, Y. H., 2022, (接受/付印) 於: Natural Product Research.

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1 引文斯高帕斯（Scopus）

New coumarins and anti-inflammatory constituents from Zanthoxylum avicennae

Cho, J. Y., Hwang, T. L., Chang, T. H., Lim, Y. P., Sung, P. J., Li, Z-H. & Chen, J. J., 11月 1 2012, 於: Food Chemistry. 135, 1, p. 17-23 7 p.

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43 引文斯高帕斯（Scopus）

New constituents with iNOS inhibitory activity from mycelium of Antrodia camphorata

Yang, S. S., Wang, G. J., Wang, S. Y., Lin, Y. Y., Kuo, Y. H. & Li, Z-H., 4月 2009, 於: Planta Medica. 75, 5, p. 512-516 5 p.

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51 引文斯高帕斯（Scopus）

New constituents from the heartwood of Picea morrisonicola HAYATA

Li, Z-H., Yeh, M. H., Chang, C. I., Lee, C. K., Shao, Y. Y. & Kuo, Y. H., 2006, 於: Chemical and Pharmaceutical Bulletin. 54, 5, p. 693-695 3 p.

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8 引文斯高帕斯（Scopus）

New constituent from Podocarpus macrophyllus var. macrophyllus shows anti-tyrosinase effect and regulates tyrosinase-related proteins and mRNA in human epidermal melanocytes

Cheng, K. T., Hsu, F. L., Chen, S. H., Hsieh, P. K., Huang, H. S., Lee, C. K. & Lee, M. H., 5月 2007, 於: Chemical and Pharmaceutical Bulletin. 55, 5, p. 757-761 5 p.

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24 引文斯高帕斯（Scopus）

New abietane-type diterpenoids from the bark of cryptomeria japonica

Chang, C. I., Chen, J. J., Hsu, C., Chen, C. C., Cheng, W. Y., Wang, S. Y., Lee, C. K., Cheng, M. J. & Kuo, Y. H., 1月 1 2019, 於: Natural Product Communications. 14, 1, p. 97-100 4 p.

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1 引文斯高帕斯（Scopus）

Neuroprotective effect of docosahexaenoic acid nanoemulsion on erectile function in a rat model of bilateral cavernous nerve injury

Liao, C. H., Wu, Y. N., Chen, B. H., Lin, Y. H., Ho, H. O. & Chiang, H-S., 9月 14 2016, 於: Scientific Reports. 6, 33040.

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9 引文斯高帕斯（Scopus）

Neuroprotective activity of vitis thunbergii var. taiwaniana extracts in vitro and in vivo

Wang, C. K., Chen, L. G., Wen, C. L., Hou, W. C., Hung, L. F., Yen, S. J., Shen, Y. J., Lin, S. Y. & Liang, Y. C., 2月 1 2010, 於: Journal of Medicinal Food. 13, 1, p. 170-178 9 p.

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16 引文斯高帕斯（Scopus）

Neurocytoprotective effects of the bioactive constituents of Pueraria thomsonii in 6-hydroxydopamine (6-OHDA)-treated nerve growth factor (NGF)-differentiated PC12 cells

Lin, C. M., Lin, R. D., Chen, S. T., Lin, Y. P., Chiu, W. T., Lin, J. W., Hsu, F. L. & Lee, M. H., 12月 2010, 於: Phytochemistry. 71, 17-18, p. 2147-2156 10 p.

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37 引文斯高帕斯（Scopus）

Neurocytoprotective effects of aliphatic hydroxamates from lovastatin, a secondary metabolite from monascus -fermented red mold rice, in 6-hydroxydopamine (6-OHDA)-Treated Nerve Growth Factor (NGF)-Differentiated PC12 Cells

Lin, C-M., Lin, Y. T., Lin, R. D., Huang, W-J. & Lee, M-H., 5月 20 2015, 於: ACS Chemical Neuroscience. 6, 5, p. 716-724 9 p.

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31 引文斯高帕斯（Scopus）

Neural cell protective compounds isolated from Phoenix hanceana var. formosana

Lin, Y. P., Chen, T. Y., Tseng, H. W., Lee, M. H. & Chen, S. T., 6月 2009, 於: Phytochemistry. 70, 9, p. 1173-1181 9 p.

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48 引文斯高帕斯（Scopus）

NBM-T-L-BMX-OS01, semisynthesized from osthole, is a novel inhibitor of histone deacetylase and enhances learning and memory in rats

Yang, Y. C., Chen, C. N., Wu, C. I., Huang, W. J., Kuo, T. Y., Kuan, M. C., Tsai, T. H., Huang, J. S. & Huang, C. Y., 2013, 於: Evidence-based Complementary and Alternative Medicine. 2013, 514908.

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16 引文斯高帕斯（Scopus）

NBM-HD-3, a novel histone deacetylase inhibitor with anticancer activity through modulation of PTEN and AKT in brain cancer cells

Huang, W. J., Lin, C. W., Lee, C. Y., Chi, L. L., Chao, Y. C., Wang, H. N., Chiou, B. L., Chen, T. J., Huang, C. Y. & Chen, C. N., 6月 14 2011, 於: Journal of Ethnopharmacology. 136, 1, p. 156-167 12 p.

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23 引文斯高帕斯（Scopus）

NBM-HD-1: A novel histone deacetylase inhibitor with anticancer activity

Huang, W. J., Liang, Y. C., Chuang, S. E., Chi, L. L., Lee, C. Y., Lin, C. W., Chen, A. L., Huang, J. S., Chiu, C. J., Lee, C. F., Huang, C. Y. & Chen, C. N., 2012, 於: Evidence-based Complementary and Alternative Medicine. 2012, 781417.

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17 引文斯高帕斯（Scopus）

Natural products of cosmetics: Analysis of extracts of plants endemic to Taiwan for the presence of tyrosinase-inhibitory, melanin-reducing, and free radical scavenging activities

Jiang, C. B., Chang, M. J., Wen, C. L., Lin, Y. P., Hsu, F-L. & Lee, M. H., 12月 2006, 於: Journal of Food and Drug Analysis. 14, 4, p. 346-352 7 p.

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14 引文斯高帕斯（Scopus）

Natural Cembrane Diterpenoids From the Soft Coral Sinularia querciformis

Wu, Y. Y., Hsieh, C. C., Li, C. Y., Chang, W. H., Chen, J. J., Lai, K. H., Wen, Z. H. & Chung, H. M., 11月 2021, 於: Natural Product Communications. 16, 11

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National prevalence of breastfeeding in Taiwan

Chien, L. Y., Chu, K. H., Tai, C. J. & Lin, C. Y., 8月 2005, 於: Journal of Human Lactation. 21, 3, p. 338-344 7 p.

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22 引文斯高帕斯（Scopus）

N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-γ induced PD-L1 expression

Mehndiratta, S., Lin, M. H., Wu, Y. W., Chen, C. H., Wu, T. Y., Chuang, K. H., Chao, M. W., Chen, Y. Y., Pan, S. L., Chen, M. C. & Liou, J. P., 1月 1 2020, 於: European Journal of Medicinal Chemistry. 185, p. 111725 111725.

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31 引文斯高帕斯（Scopus）

Myricetin as the active principle of Abelmoschus moschatus to lower plasma glucose in streptozotocin-induced diabetic rats

Liu, I. M., Liou, S. S., Lan, T. W., Hsu, F. L. & Cheng, J. T., 7月 2005, 於: Planta Medica. 71, 7, p. 617-621 5 p.

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71 引文斯高帕斯（Scopus）

Mycelial mattress from a sporangia formation-delayed mutant of Rhizopus stoloniferas wound healing-enhancing biomaterial

Chien, M. Y., Chen, L. C., Chen, Y. C., Sheu, M. T., Tsai, Y. C., Ho, H. O., Su, C. H. & Liu, D. Z., 8月 14 2015, 於: PLoS ONE. 10, 8, e0134090.

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5 引文斯高帕斯（Scopus）

Multiple activities of punica granatum linne against acne vulgaris

Lee, C-J., Chen, L. G., Liang, W-L. & Wang, C-C., 1月 12 2017, 於: International Journal of Molecular Sciences. 18, 1, 141.

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35 引文斯高帕斯（Scopus）

MPT0G612, a novel HDAC6 inhibitor, induces apoptosis and suppresses ifn-Γ-induced programmed death-ligand 1 in human colorectal carcinoma cells

Chen, M. C., Lin, Y. C., Liao, Y. H., Liou, J. P. & Chen, C. H., 10月 2019, 於: Cancers. 11, 10, 1617.

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20 引文斯高帕斯（Scopus）

MPT0G066, a novel anti-mitotic drug, induces JNK-independent mitotic arrest, JNK-mediated apoptosis, and potentiates antineoplastic effect of cisplatin in ovarian cancer

Huang, H. L., Chao, M. W., Li, Y. C., Chang, L. H., Chen, C-H., Chen, M. C., Cheng, C. C., Liou, J. P., Teng, C. M. & Pan, S. L., 8月 16 2016, 於: Scientific Reports. 6, 31664.

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12 引文斯高帕斯（Scopus）

Moscatilin, a bibenzyl derivative from the India orchid Dendrobrium loddigesii, suppresses tumor angiogenesis and growth in vitro and in vivo

Tsai, A. C., Pan, S. L., Liao, C. H., Guh, J. H., Wang, S. W., Sun, H. L., Liu, Y. N., Chen, C. C., Shen, C. C., Chang, Y. L. & Teng, C. M., 6月 2010, 於: Cancer Letters. 292, 2, p. 163-170 8 p.

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57 引文斯高帕斯（Scopus）

Monosaccharide Composition Analysis of Immunostimulating Subfraction from Auricularia auricula-judae Hot Water Extract

Chung, H. C., Hsu, S. J., Yu, Z. R., Lee, C. K., Wang, B. J. & Lin, S. M., 12月 2021, 於: Taiwanese Journal of Agricultural Chemistry and Food Science. 59, 4, p. 118-129 12 p.

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