生藥學研究所

2023

A new capnellene skeleton from the octocoral Capnella imbricata (Quoy & Gaimard, 1833)

Wu, I. T., Fan, Y. C., Lin, G. Z., Wang, Y. L., Hwang, T. L., Lai, K. H. & Chung, H. M., 1月 2023, 於: Journal of Molecular Structure. 1271, 133995.

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Antihyperglycemic and Anti-inflammatory Activities of Traditional Philippine Herbal Formula (Pito-pito)

Ramos, J. L. T., Hsieh, C. Y., Lee, C. J., De Castro-Cruz, K. A. & Tsai, P. W., 2023, 於: Biointerface Research in Applied Chemistry. 13, 1, 99.

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Biological Properties and Phytonutrient Profile of Beans: Vigna angularis, Vigna radiata, and Glycine max

Hsieh, C. Y., Tsai, J. R., Lee, C. J., Ciou, Y. R., Li, J. S., Tayo, L. L. & Tsai, P. W., 2月 15 2023, 於: Biointerface Research in Applied Chemistry. 13, 1, 53.

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2 引文斯高帕斯（Scopus）

Structures of the xyloglucans in the monocotyledon family Araceae (aroids)

Hsiung, S-Y., Li, J., Imre, B., Kao, M-R., Liao, H-C., Wang, D., Chen, C-H., Liang, P-H., Harris, P. J. & Hsieh, Y. S. Y., 2023, 於: Planta. 257, 2

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2022

2, 3, 5, 4’-tetrahydroxystilbene-2-O-beta-D-glucoside protects against neuronal cell death and traumatic brain injury-induced pathophysiology

Chen, Y. H., Chen, Y. C., Chin, Y. T., Wang, C. C., Hwang, L. L., Yang, L. Y. & Lu, D. Y., 2022, 於: Aging. 14, 6, p. 2607-2627 21 p.

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1 引文斯高帕斯（Scopus）

Acteoside exerts immunomodulatory effects on dendritic cells via aryl hydrocarbon receptor activation and ameliorates Th2-mediated allergic asthma by inducing Foxp3⁺ regulatory T cells

Chang, J. H., Chuang, H. C., Hsiao, G., Hou, T. Y., Wang, C. C., Huang, S. C., Li, B. Y. & Lee, Y. L., 5月 2022, 於: International Immunopharmacology. 106, 108603.

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6 引文斯高帕斯（Scopus）

A new angular naphthopyrone from feather star Comanthus parvicirrus (Müller, 1841)

Ke, Z. Y., Chen, J. W., Wu, B. Y., Jhan, Y. Y., Wen, Z. H., Kung, T. A., Sung, P. J., Chen, J. J., Lai, K. H. & Chung, H. M., 4月 5 2022, 於: Journal of Molecular Structure. 1253, 132261.

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A novel anti-tumor/anti-tumor-associated fibroblast/anti-mPEG tri-specific antibody to maximize the efficacy of mPEGylated nanomedicines against fibroblast-rich solid tumor

Chen, M., Sheu, M. T., Cheng, T. L., Roffler, S. R., Lin, S. Y., Chen, Y. J., Cheng, Y. A., Cheng, J. J., Chang, H. Y., Wu, T. Y., Kao, A. P., Ho, Y. S. & Chuang, K. H., 1月 7 2022, 於: Biomaterials Science. 10, 1, p. 202-215 14 p.

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3 引文斯高帕斯（Scopus）

Anti-adipogenic activities of pheophorbide a and pyropheophorbide a isolated from wild bitter gourd (Momordica charantia L. var. abbreviata Seringe) in vitro

Liu, Y. H., Lu, Y. L., Chang, Y. C., Chyuan, J. H., Lee, T. H. & Hou, W. C., 2022, (接受/付印) 於: Journal of the Science of Food and Agriculture.

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A Real-World Study on Ge Gen Tang in Combination with Herbal Medicines for Relieving Common Cold-Associated Symptoms

Chou, P. Y., Tai, C. J., Tang, Y. J., Chen, Y. C., Lin, K. Y. & Wang, C. C., 2022, 於: Evidence-based Complementary and Alternative Medicine. 2022, 4790910.

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Ascophyllum nodosum and Fucus vesiculosus Extracts Improved Lipid Metabolism and Inflammation in High-Energy Diet–Induced Hyperlipidemia Rats

Tung, Y. T., Wu, C. H., Chen, W. C., Pan, C. H., Chen, Y. W., Tsao, S. P., Chen, C. J. & Huang, H. Y., 11月 2022, 於: Nutrients. 14, 21, 4665.

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A universal in silico V(D)J recombination strategy for developing humanized monoclonal antibodies

Hsieh, Y. C., Liao, J. M., Chuang, K. H., Ho, K. W., Hong, S. T., Liu, H. J., Huang, B. C., Chen, I. J., Liu, Y. L., Wang, J. Y., Tsai, H. L., Su, Y. C., Wang, Y. T. & Cheng, T. L., 1月 31 2022, 於: Journal of Nanobiotechnology. 20, 1, p. 58 58.

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Bispecific T-cell engagers non-covalently decorated drug-loaded PEGylated nanocarriers for cancer immunochemotherapy

Cheng, W. J., Chuang, K. H., Lo, Y. J., Chen, M., Chen, Y. J., Roffler, S. R., Ho, H. O., Lin, S. Y. & Sheu, M. T., 4月 2022, 於: Journal of Controlled Release. 344, p. 235-248 14 p.

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4 引文斯高帕斯（Scopus）

Chemical constituents and their anti-neuroinflammatory activities from the bark of Taiwan incense cedar, Calocedrus formosana

Wu, H. C., Chen, Y. C., Hsieh, C. L., Hsiao, G., Wang, S. W., Cheng, M. J., Chao, C. Y., Lee, T. H. & Kuo, Y. H., 12月 2022, 於: Phytochemistry. 204, 113347.

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Chemical Constituents of the Formosan Soft Coral Sinularia querciformis

Hsieh, C. C., Wu, Y. Y., Peng, B. R., Lai, K. H., Liao, M. Y. & Chung, H. M., 2022, (接受/付印) 於: Chemistry of Natural Compounds. 58, 5, p. 975-977 3 p.

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Chemical investigations and cytotoxic effects of metabolites from Antrodia camphorata against human hepatocellular carcinoma cells

Chen, Y. F., Wu, H. C., Chang, J. M., Ko, H. H., Lin, C. H. & Chang, H. S., 2022, (接受/付印) 於: Natural Product Research.

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1 引文斯高帕斯（Scopus）

Chemometric-Guided Exploration of Marine Anti-Neurofibroma Leads

Chen, L. Y., Peng, B. R., Lai, G. Y., Weng, H. J., El-Shazly, M., Su, C. H., Su, J. H., Sung, P. J., Liao, C. P. & Lai, K. H., 7月 13 2022, 於: Frontiers in Marine Science. 9, 930736.

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1 引文斯高帕斯（Scopus）

Cinnamic aldehyde, an anti-inflammatory component in Du-Huo-Ji-Sheng-Tang, ameliorates arthritis in II collagenase and monosodium iodoacetate induced osteoarthritis rat models

Tseng, S. H., Lee, C. J., Chen, S. H., Chen, C. H., Tsai, P. W., Hsieh, M. S., Chu, J. S. & Wang, C. C., 2022, (接受/付印) 於: Journal of Traditional and Complementary Medicine. 13, 1, p. 51-61 11 p.

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Combined Docetaxel/Pictilisib-Loaded mPEGylated Nanocarriers with Dual HER2 Targeting Antibodies for Synergistic Chemotherapy of Breast Cancer

Cheng, W. J., Lin, S. Y., Chuang, K. H., Chen, M., Ho, H. O., Chen, L. C., Hsieh, C. M. & Sheu, M. T., 2022, 於: International Journal of Nanomedicine. 17, p. 5353-5374 22 p.

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Cytotoxicity Effect of Constituents of Pinus taiwanensis Hayata Twigs on B16-F10 Melanoma Cells

Chu, M. H., Hsiao, S. W., Kao, Y. C., Yin, H. W., Kuo, Y. H. & Lee, C. K., 5月 2022, 於: Molecules. 27, 9, 2731.

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Deer Velvet Antler Extracts Exert Anti-Inflammatory and Anti-Arthritic Effects on Human Rheumatoid Arthritis Fibroblast-Like Synoviocytes and Distinct Mouse Arthritis

Cheng, W. J., Yang, H. T., Chiang, C. C., Lai, K. H., Chen, Y. L., Shih, H. L., Kuo, J. J., Hwang, T. L. & Lin, C. C., 2022, 於: American Journal of Chinese Medicine. 50, 6, p. 1617-1643 27 p.

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2 引文斯高帕斯（Scopus）

Discovery of a novel cyclin-dependent kinase 8 inhibitor with an oxindole core for anti-inflammatory treatment

Lin, T. E., Yang, C. R., Chou, C. H., Hsu, J. Y., Chao, M. W., Sung, T. Y., Hsieh, J. H., Huang, W. J. & Hsu, K. C., 2月 2022, 於: Biomedicine and Pharmacotherapy. 146, 112459.

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2 引文斯高帕斯（Scopus）

Efficacy and safety of Duhuo Jisheng Decoction add-on bisphosphonate medications in patients with osteoporosis: A meta-analysis of randomized controlled trials

Huang, C. Y., Cheng, C. J., Chiou, W. F., Chang, W. C., Kang, Y. N. & Lee, M. H., 1月 30 2022, 於: Journal of Ethnopharmacology. 283, 114732.

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1 引文斯高帕斯（Scopus）

Endoplasmic Reticulum Stress of Oral Squamous Cell Carcinoma Induces Immunosuppression of Neutrophils

Wu, C. F., Hung, T. T., Su, Y. C., Chen, P. J., Lai, K. H. & Wang, C. C., 3月 16 2022, 於: Frontiers in Oncology. 12, 818192.

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1 引文斯高帕斯（Scopus）

Estrogenic and anti-neutrophilic inflammatory phenanthrenes from Juncus effusus L.

Hu, H. C., Tsai, Y. H., Chuang, Y. C., Lai, K. H., Hsu, Y. M., Hwang, T. L., Lin, C. C., Fülöp, F., Wu, Y. C., Yu, S. Y., Kuo, Y. T. & Chang, F. R., 2022, 於: Natural Product Research. 36, 12, p. 3043-3053 11 p.

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2 引文斯高帕斯（Scopus）

Exploring the relationship between metabolite composition and the cold/hot properties ascribed in traditional Chinese medicine by mass spectral molecular networking e A pilot study

Su, C. H., Cheng, Y. C., Lai, K. H., Chang, Y. C., Sun, C. H., Tu, P. W., Lin, C. C., Hwang, T. L. & Yang, Y. L., 2022, 於: Journal of Food and Drug Analysis. 30, 3, p. 402-416 15 p.

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Glycosylation of OVA antigen-loaded PLGA nanoparticles enhances DC-targeting for cancer vaccination

Chou, P. Y., Lin, S. Y., Wu, Y. N., Shen, C. Y., Sheu, M. T. & Ho, H. O., 11月 2022, 於: Journal of Controlled Release. 351, p. 970-988 19 p.

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1 引文斯高帕斯（Scopus）

Hypermethylation of TMEM240 predicts poor hormone therapy response and disease progression in breast cancer

Lin, R. K., Su, C. M., Lin, S. Y., Thi Anh Thu, L., Liew, P. L., Chen, J. Y., Tzeng, H. E., Liu, Y. R., Chang, T. H., Lee, C. Y. & Hung, C. S., 12月 2022, 於: Molecular Medicine. 28, 1, 67.

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4 引文斯高帕斯（Scopus）

Identification of a dual FLT3 and MNK2 inhibitor for acute myeloid leukemia treatment using a structure-based virtual screening approach

Yen, S. C., Chen, L. C., Huang, H. L., HuangFu, W. C., Chen, Y. Y., Eight Lin, T., Lien, S. T., Tseng, H. J., Sung, T. Y., Hsieh, J. H., Huang, W. J., Pan, S. L. & Hsu, K. C., 4月 2022, 於: Bioorganic Chemistry. 121, p. 105675 105675.

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2 引文斯高帕斯（Scopus）

KI Essence extract (a spleen-tonifying formula) promotes neurite outgrowth, alleviates oxidative stress and hypomyelination, and modulates microbiome in maternal immune activation offspring

Lee, G. A., Zhao, H. W., Chang, Y. W., Lee, C. J., Yang, Y. C. S. H., Wu, Y. C., Lin, W. L., Liu, Y. R., Ning, D. S. & Tseng, S. H., 8月 25 2022, 於: Frontiers in Pharmacology. 13, 964255.

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Lonicerae Japonicae Flos Attenuates Neutrophilic Inflammation by Inhibiting Oxidative Stress

Lai, K. H., Chen, Y. L., Lin, M. F., El-Shazly, M., Chang, Y. C., Chen, P. J., Su, C. H., Chiu, Y. C., Illias, A. M., Chen, C. C., Chen, L. Y. & Hwang, T. L., 9月 2022, 於: Antioxidants. 11, 9, 1781.

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1 引文斯高帕斯（Scopus）

New ent-kaurene and germacrene derivatives from Mesona procumbens Hemseley and their biological activity

Ganzon, J. G., Liaw, C. C., Lin, Y. C., Lin, Z. H., Wang, C. H., Chen, C. Y., Chuang, K. H. & Kuo, Y. H., 2022, (接受/付印) 於: Natural Product Research.

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1 引文斯高帕斯（Scopus）

Novel Two-Step Process in Cellulose Depolymerization: Hematite-Mediated Photocatalysis by Lytic Polysaccharide Monooxygenase and Fenton Reaction

Wang, D., Kao, M-R., Li, J., Sun, P., Meng, Q., Vyas, A., Liang, P-H., Wang, Y-S. & Hsieh, Y. S. Y., 8月 17 2022, 於: Journal of Agricultural and Food Chemistry. 70, 32, p. 9941-9947 7 p.

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1 引文斯高帕斯（Scopus）

Oct-4 induces cisplatin resistance and tumor stem cell-like properties in endometrial carcinoma cells

Lin, T. C., Wang, K. H., Chuang, K. H., Kao, A. P. & Kuo, T. C., 2022, (接受/付印) 於: Taiwanese Journal of Obstetrics and Gynecology.

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O-methylated flavonol as a multi-kinase inhibitor of leukemogenic kinases exhibits a potential treatment for acute myeloid leukemia

Yen, S. C., Wu, Y. W., Huang, C. C., Chao, M. W., Tu, H. J., Chen, L. C., Lin, T. E., Sung, T. Y., Tseng, H. J., Chu, J. C., Huang, W. J., Yang, C. R., HuangFu, W. C., Pan, S. L. & Hsu, K. C., 6月 2022, 於: Phytomedicine. 100, 154061.

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3 引文斯高帕斯（Scopus）

Pharmacokinetic Herb-Drug Interactions of Xiang-Sha-Liu-Jun-Zi-Tang and Paclitaxel in Male Sprague Dawley Rats and Its Influence on Enzyme Kinetics in Human Liver Microsomes

Kapelemera, A. M., Uang, Y-S., Wang, L-H., Wu, T-Y., Lee, F-Y., Tai, L., Wang, C-C. & Lee, C-J., 2022, 於: Frontiers in Pharmacology. 13

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1 引文斯高帕斯（Scopus）

Photo-Programmed Deformations in Rigid Liquid Crystalline Polymers Triggered by Body Temperature

Kim, H., Li, J., Hsieh, Y. S. Y., Cho, M., Ahn, S-H. & Li, C., 2022, 於: Small.

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Predictive Model for Oral Status in Elderly People in a Taiwanese Nursing Home Using a High-Protein Black Soybean Koji Food

Liao, K-W., Lo, W-L., Hsu, C-Y., Chiu, W-C., Wu, C-H., Chen, Y-W., Hsu, P-C. & Huang, H-Y., 4月 2022, 於: Frontiers in Nutrition. 9, p. 814315

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Probing Anti-Leukemic Metabolites from Marine-Derived Streptomyces sp. LY1209

Chen, Y-Y., Chen, L-Y., Chen, P-J., El-Shazly, M., Peng, B-R., Chen, Y-C., Su, C-H., Su, J-H., Sung, P-J., Yen, P-T., Wang, L-S. & Lai, K-H., 4月 2 2022, 於: Metabolites. 12, 4, 320.

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Probiotic supplementation attenuates age-related sarcopenia via the gut–muscle axis in SAMP8 mice

Chen, L. H., Chang, S. S., Chang, H. Y., Wu, C. H., Pan, C. H., Chang, C. C., Chan, C. H. & Huang, H. Y., 2月 2022, 於: Journal of Cachexia, Sarcopenia and Muscle. 13, 1, p. 515-531 17 p.

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6 引文斯高帕斯（Scopus）

Rational design of synthetically tractable HDAC6/HSP90 dual inhibitors to destroy immune-suppressive tumor microenvironment

Wu, T. Y., Chen, M., Chen, I. C., Chen, Y. J., Chen, C. Y., Wang, C. H., Cheng, J. J., Nepali, K., Chuang, K. H. & Liou, J. P., 2022, (接受/付印) 於: Journal of Advanced Research.

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1 引文斯高帕斯（Scopus）

Structural compositions and biological activities of cell wall polysaccharides in the rhizome, stem, and leaf of Polygonatum odoratum (Mill.) Druce

Li, J., Hsiung, S. Y., Kao, M. R., Xing, X., Chang, S. C., Wang, D., Hsieh, P. Y., Liang, P. H., Zhu, Z., Cheng, T. J. R., Shie, J. J., Liou, J. P., Abbott, D. W., Kwon, S. W. & Hsieh, Y. S. Y., 11月 2022, 於: Carbohydrate Research. 521, 108662.

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Synergistic deciphering of bioenergy production and electron transport characteristics to screen traditional Chinese medicine (TCM) for COVID-19 drug development

Tsai, P. W., Hsieh, C. Y., Ting, J. U., Ciou, Y. R., Lee, C. J., Hsieh, C. L., Lien, T. K., Hsueh, C. C. & Chen, B. Y., 6月 2022, 於: Journal of the Taiwan Institute of Chemical Engineers. 135, 104365.

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3 引文斯高帕斯（Scopus）

The Design, Structure–Activity, and kinetic studies of 3-Benzyl-5-oxa-1,2,3,4-Tetrahydro-2H-chromeno-(3,4-c)pyridin-8-yl sulfamates as Steroid sulfatase inhibitors

Chang, C-N., Lin, I-C., Lin, T-S., Chiu, P-F., Lu, Y-L., Narwane, M., Liu, I-C., Hng, Y., Tsai, K-C., Lin, M-H., S. Y. Hsieh, Y., Chen, M-J. & Liang, P-H., 2022, 於: Bioorganic Chemistry. 129

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Undescribed alkyne-geranylcyclohexenetriols from the endophyte Diaporthe caulivora 09F0132 and their anti-melanogenic activity

Yang, S. S., Chen, Y. F., Ko, H. H., Wu, H. C., Hsieh, S. Y., Wu, M. D., Cheng, M. J. & Chang, H. S., 10月 2022, 於: Phytochemistry. 202, 113312.

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Untargeted LC-MS/MS-Based Multi-Informative Molecular Networking for Targeting the Antiproliferative Ingredients in Tetradium ruticarpum Fruit

Su, C. H., Cheng, Y. C., Chang, Y. C., Kung, T. H., Chen, Y. L., Lai, K. H., Hsieh, H. L., Chen, C. Y., Hwang, T. L. & Yang, Y. L., 7月 2022, 於: Molecules. 27, 14, 4462.

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Vitisin A, a Resveratrol Tetramer, Improves Scopolamine-Induced Impaired Learning and Memory Functions in Amnesiac ICR Mice

Chen, L. G., Wang, C. C., Lee, Y. S., Sie, Y. Y., Chang, C. I. & Hou, W. C., 2月 2022, 於: Biomedicines. 10, 2, 273.

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1 引文斯高帕斯（Scopus）

2021

Achieving High Power Density and Long-Term Stable Flexible Triboelectric Nanogenerators through Surface Functionalization of High Work-Function Electrode with Cationic Thiol-Based Self-Assembled Monolayer

Cheng, Y. H., Lee, C. J. & Chang, C. Y., 3月 2021, 於: Advanced Materials Technologies. 6, 3, 2000985.

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4 引文斯高帕斯（Scopus）

Active Tumoral/Tumor Environmental Dual-Targeting by Non-Covalently Arming with Trispecific Antibodies or Dual-Bispecific Antibodies on Docetaxel-Loaded mPEGylated Nanocarriers to Enhance Chemotherapeutic Efficacy and Minimize Systemic Toxicity

Cheng, W. J., Lin, S. Y., Chen, M., Chen, L. C., Ho, H. O., Chuang, K. H. & Sheu, M. T., 2021, 於: International Journal of Nanomedicine. 16, p. 4017-4030 14 p.

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4 引文斯高帕斯（Scopus）

An electrostatically self-assembled fluorinated molecule as a surface modification layer for a high-performance and stable triboelectric nanogenerator

Yang, J. R., Lee, C. J. & Chang, C. Y., 2月 2021, 於: Journal of Materials Chemistry A. 9, 7, p. 4230-4239 10 p.

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8 引文斯高帕斯（Scopus）

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