生藥學研究所

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Glycine hydroxamate inhibits tyrosinase activity and melanin contents through downregulating cAMP/PKA signaling pathways

Lin, Y. S., Wu, W. C., Lin, S. Y. & Hou, W. C., 2015, 於: Amino Acids. 47, 3, p. 617-625 9 p.

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Glycosylation of OVA antigen-loaded PLGA nanoparticles enhances DC-targeting for cancer vaccination

Chou, P. Y., Lin, S. Y., Wu, Y. N., Shen, C. Y., Sheu, M. T. & Ho, H. O., 11月 2022, 於: Journal of Controlled Release. 351, p. 970-988 19 p.

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1 引文斯高帕斯（Scopus）

Glycyrrhizic acid induces apoptosis in WEHI-3 mouse leukemia cells through the caspase- and mitochondria-dependent pathways

Chueh, F. S., Hsiao, Y. T., Chang, S. J., Wu, P. P., Yang, J. S., Lin, J. J., Chung, J. G. & Lai, T-I., 12月 2012, 於: Oncology Reports. 28, 6, p. 2069-2076 8 p.

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31 引文斯高帕斯（Scopus）

Growth stimulating effect on queen bee larvae of histone deacetylase inhibitors

Huang, C. Y., Chi, L. L., Huang, W. J., Chen, Y. W., Chen, W. J., Kuo, Y. C., Yuan, C. M. & Chen, C. N., 6月 20 2012, 於: Journal of Agricultural and Food Chemistry. 60, 24, p. 6139-6149 11 p.

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20 引文斯高帕斯（Scopus）

HDAC8 Inhibition Specifically Targets Inv(16) Acute Myeloid Leukemic Stem Cells by Restoring p53 Acetylation

Qi, J., Singh, S., Hua, W. K., Cai, Q., Chao, S. W., Li, L., Liu, H., Ho, Y., McDonald, T., Lin, A., Marcucci, G., Bhatia, R., Huang, W. J., Chang, C. I. & Kuo, Y. H., 11月 5 2015, 於: Cell Stem Cell. 17, 5, p. 597-610 14 p.

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64 引文斯高帕斯（Scopus）

HDAC8 inhibitor WK2-16 therapeutically targets lipopolysaccharide-induced mouse model of neuroinflammation and microglial activation

Lin, F. L., Yen, J. L., Kuo, Y. C., Kang, J. J., Cheng, Y. W., Huang, W. J. & Hsiao, G., 1月 2 2019, 於: International Journal of Molecular Sciences. 20, 2, p. 410 410.

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15 引文斯高帕斯（Scopus）

Heme oxygenase-1 inhibits breast cancer invasion via suppressing the expression of matrix metalloproteinase-9

Lin, C. W., Shen, S. C., Hou, W. C., Yang, L. Y. & Chen, Y. C., 2008, 於: Molecular Cancer Therapeutics. 7, 5, p. 1195-1206 12 p.

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114 引文斯高帕斯（Scopus）

Hepatoprotection by "Dangqui-Long-Hwei-Wan" in male mice

Chen, J. H., Ho, H. O., Yen, K. Y. & Yang, L-L., 2000, 於: American Journal of Chinese Medicine. 28, 1, p. 115-121 7 p.

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3 引文斯高帕斯（Scopus）

Hepatoprotective Activity of the Ethanolic Extract of Polygonum multiflorum Thunb. against Oxidative Stress-Induced Liver Injury

Lin, E. Y., Chagnaadorj, A., Huang, S. J., Wang, C-C., Chiang, Y-H. & Cheng, C-W., 2018, 於: Evidence-based Complementary and Alternative Medicine. 9 p.

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16 引文斯高帕斯（Scopus）

Hepatoprotective effect of the aqueous extract of flemingia macrophylla on carbon tetrachloride-induced acute hepatotoxicity in rats through anti-oxidative activities

Hsieh, P. C., Ho, Y. L., Huang, G. J., Huang, M. H., Chiang, Y. C., Huang, S. S., Hou, W. C. & Chang, Y. S., 2011, 於: American Journal of Chinese Medicine. 39, 2, p. 349-365 17 p.

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18 引文斯高帕斯（Scopus）

Hepatoprotective effect of the ethanol extract of Vitis thunbergii on carbon tetrachloride-induced acute hepatotoxicity in rats through anti-oxidative activities

Deng, J. S., Chang, Y. C., Wen, C. L., Liao, J. C., Hou, W. C., Amagaya, S., Huang, S. S. & Huang, G. J., 8月 1 2012, 於: Journal of Ethnopharmacology. 142, 3, p. 795-803 9 p.

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42 引文斯高帕斯（Scopus）

Hepatoprotective effects of eburicoic acid and dehydroeburicoic acid from Antrodia camphorata in a mouse model of acute hepatic injury

Huang, G. J., Deng, J. S., Huang, S. S., Lee, C. Y., Hou, W. C., Wang, S. Y., Sung, P. J. & Kuo, Y. H., 2013, 於: Food Chemistry. 141, 3, p. 3020-3027 8 p.

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58 引文斯高帕斯（Scopus）

Heptadecanols from the leaves of Persea americana var. americana

Li, Z-H., Tsai, Y. F., Huang, T. T., Chen, P. Y., Liang, W. L. & Lee, C. K., 5月 15 2012, 於: Food Chemistry. 132, 2, p. 921-924 4 p.

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14 引文斯高帕斯（Scopus）

Highly bioavailable silibinin nanoparticles inhibit HCV infection

Liu, C. H., Lin, C. C., Hsu, W. C., Chung, C. Y., Lin, C. C., Jassey, A., Chang, S. P., Tai, C. J., Tai, C. J., Shields, J., Richardson, C. D., Yen, M. H., Tyrrell, D. L. J. & Lin, L. T., 10月 2017, 於: Gut. 66, 10, p. 1853-1861 9 p.

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24 引文斯高帕斯（Scopus）

High-performance liquid chromatographic analysis for the characterization of triterpenoids from Ganoderma

Su, C. H., Yang, Y. Z., Ho, H. O., Hu, J-H. & Sheu, M. T., 3月 2001, 於: Journal of Chromatographic Science. 39, 3, p. 93-100 8 p.

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34 引文斯高帕斯（Scopus）

High-performance liquid chromatographic method for determination of tramadol in human plasma

Yeh, G. C., Sheu, M. T., Yen, C. L., Wang, Y. W., Liu, C. H. & Ho, H. O., 2月 19 1999, 於: Journal of Chromatography B: Biomedical Sciences and Applications. 723, 1-2, p. 247-253 7 p.

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53 引文斯高帕斯（Scopus）

High performance liquid chromatography analysis of tetrahydrozoline hydrochloride in ophthalmic solution by silica column eluted with aqueous solvent mixtures

Huang, M. C., Ho, H. O., Wen, K. C. & Sheu, M. T., 2002, 於: Journal of Food and Drug Analysis. 10, 2, p. 88-94 7 p.

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5 引文斯高帕斯（Scopus）

High-throughput sorting of the highest producing cell via a transiently protein-anchored system

Chuang, K. H., Hsieh, Y. C., Chiang, I. S., Chuang, C. H., Kao, C. H., Cheng, T. C., Wang, Y. T., Lin, W. W., Chen, B. M., Roffler, S. R., Huang, M. Y. & Cheng, T. L., 7月 18 2014, 於: PLoS One. 9, 7, e102569.

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7 引文斯高帕斯（Scopus）

Hispidulin, a constituent of Clerodendrum inerme that remitted motor tics, alleviated methamphetamine-induced hyperlocomotion without motor impairment in mice

Huang, W. J., Lee, H. J., Chen, H. L., Fan, P. C., Ku, Y. L. & Chiou, L. C., 5月 26 2015, 於: Journal of Ethnopharmacology. 166, p. 18-22 5 p.

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25 引文斯高帕斯（Scopus）

Hispidulin alleviated methamphetamine-induced hyperlocomotion by acting at α6 subunit-containing GABA_A receptors in the cerebellum

Liao, Y. H., Lee, H. J., Huang, W. J., Fan, P. C. & Chiou, L. C., 9月 1 2016, 於: Psychopharmacology. 233, 17, p. 3187-3199 13 p.

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15 引文斯高帕斯（Scopus）

Hispidulin attenuates the social withdrawal in isolated disrupted-in-schizophrenia-1 mutant and chronic phencyclidine-treated mice

Mouri, A., Lee, H. J., Mamiya, T., Aoyama, Y., Matsumoto, Y., Kubota, H., Huang, W. J., Chiou, L. C. & Nabeshima, T., 7月 2020, 於: British Journal of Pharmacology. 177, 14, p. 3210-3224 15 p.

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8 引文斯高帕斯（Scopus）

Hispolon suppresses SK-Hep1 human hepatoma cell metastasis by inhibiting matrix metalloproteinase-2/9 and urokinase-plasminogen activator through the PI3K/Akt and ERK signaling pathways

Huang, G. J., Yang, C. M., Chang, Y. S., Amagaya, S., Wang, H. C., Hou, W. C., Huang, S. S. & Hu, M. L., 9月 8 2010, 於: Journal of Agricultural and Food Chemistry. 58, 17, p. 9468-9475 8 p.

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65 引文斯高帕斯（Scopus）

Hot water-extracted Lycium barbarum and Rehmannia glutinosa inhibit proliferation and induce apoptosis of hepatocellular carcinoma cells

Chao, J. C. J., Chiang, S. W., Wang, C. C., Tsai, Y-H. & Wu, M. S., 7月 28 2006, 於: World Journal of Gastroenterology. 12, 28, p. 4478-4484 7 p.

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81 引文斯高帕斯（Scopus）

Humanized bispecific antibody (mPEG × HER2) rapidly confers PEGylated nanoparticles tumor specificity for multimodality imaging in breast cancer

Cheng, Y. A., Wu, T. H., Wang, Y. M., Cheng, T. L., Chen, I. J., Lu, Y. C., Chuang, K. H., Wang, C. K., Chen, C. Y., Lin, R. A., Chen, H. J., Liao, T. Y., Liu, E. S. & Chen, F. M., 8月 27 2020, 於: Journal of Nanobiotechnology. 18, 1, p. 118 118.

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4 引文斯高帕斯（Scopus）

Hydrolysable tannins exhibit acetylcholinesterase inhibitory and anti-glycation activities in vitro and learning and memory function improvements in scopolamine-induced amnesiac mice

Chen, L. G., Lin, S. Y., Lee, Y. S., Wang, C. C. & Hou, W. C., 8月 2021, 於: Biomedicines. 9, 8, 1066.

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2 引文斯高帕斯（Scopus）

Hypermethylation and decreased expression of TMEM240 are potential early-onset biomarkers for colorectal cancer detection, poor prognosis, and early recurrence prediction

Chang, S. C., Liew, P. L., Ansar, M., Lin, S. Y., Wang, S. C., Hung, C. S., Chen, J. Y., Jain, S. & Lin, R. K., 5月 12 2020, 於: Clinical Epigenetics. 12, 1, p. 67 67.

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9 引文斯高帕斯（Scopus）

Hypermethylation of BEND5 contributes to cell proliferation and is a prognostic marker of colorectal cancer

Lin, R. K., Hung, W. Y., Huang, Y. F., Chang, Y. J., Lin, C. H., Chen, W. Y., Chiu, S-F., Chang, S. C. & Tsai, S. F., 2017, 於: Oncotarget. 8, 69, p. 113431-113443 13 p.

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10 引文斯高帕斯（Scopus）

Hypermethylation of CCND2 in Lung and Breast Cancer Is a Potential Biomarker and Drug Target

Hung, C. S., Wang, S. C., Yen, Y. T., Lee, T. H., Wen, W. C. & Lin, R. K., 10月 10 2018, 於: International Journal of Molecular Sciences. 19, 10, 3096.

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36 引文斯高帕斯（Scopus）

Hypermethylation of TMEM240 predicts poor hormone therapy response and disease progression in breast cancer

Lin, R. K., Su, C. M., Lin, S. Y., Thi Anh Thu, L., Liew, P. L., Chen, J. Y., Tzeng, H. E., Liu, Y. R., Chang, T. H., Lee, C. Y. & Hung, C. S., 12月 2022, 於: Molecular Medicine. 28, 1, 67.

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4 引文斯高帕斯（Scopus）

Hypoglycemic effect of syringin from Eleutherococcus senticosus in streptozotocin-induced diabetic rats

Niu, H. S., Liu, I. M., Cheng, J. T., Lin, C. L. & Hsu, F. L., 2月 2008, 於: Planta Medica. 74, 2, p. 109-113 5 p.

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69 引文斯高帕斯（Scopus）

Hypolipidemic effects of three purgative decoctions

Wang, C. C., Tseng, S. H., Chien, T. Y., Chen, J. R. & Lin, I. H., 2011, 於: Evidence-based Complementary and Alternative Medicine. 2011, 249254.

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9 引文斯高帕斯（Scopus）

Hypoxia-inducible factor 1α regulates lung adenocarcinoma cell invasion

Shyu, K. G., Hsu, F. L., Wang, M. J., Wang, B. W. & Lin, S., 4月 1 2007, 於: Experimental Cell Research. 313, 6, p. 1181-1191 11 p.

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57 引文斯高帕斯（Scopus）

Identification of 7-(4′-Cyanophenyl)indoline-1-benzenesulfonamide as a mitotic inhibitor to induce apoptotic cell death and inhibit autophagy in human colorectal cancer cells

Wu, T. Y., Cho, T. Y., Lu, C. K., Liou, J. P. & Chen, M. C., 12月 1 2017, 於: Scientific Reports. 7, 1, 12406.

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9 引文斯高帕斯（Scopus）

Identification of a dual FLT3 and MNK2 inhibitor for acute myeloid leukemia treatment using a structure-based virtual screening approach

Yen, S. C., Chen, L. C., Huang, H. L., HuangFu, W. C., Chen, Y. Y., Eight Lin, T., Lien, S. T., Tseng, H. J., Sung, T. Y., Hsieh, J. H., Huang, W. J., Pan, S. L. & Hsu, K. C., 4月 2022, 於: Bioorganic Chemistry. 121, p. 105675 105675.

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2 引文斯高帕斯（Scopus）

Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach

Chao, M. W., Lin, T. E., HuangFu, W. C., Chang, C. D., Tu, H. J., Chen, L. C., Yen, S. C., Sung, T. Y., Huang, W. J., Yang, C. R., Pan, S. L. & Hsu, K. C., 12月 2021, 於: Journal of Enzyme Inhibition and Medicinal Chemistry. 36, 1, p. 98-108 11 p.

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3 引文斯高帕斯（Scopus）

Identification of Anoectochilus formosanus and Anoectochilus koshunensis species with RAPD markers

Cheng, K-T., Fu, L. C., Wang, C. S., Hsu, F-L. & Tsay, H. S., 1998, 於: Planta Medica. 64, 1, p. 46-49 4 p.

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17 引文斯高帕斯（Scopus）

Identification of dried rhizomes of Coptis species using random amplified polymorphic DNA

Cheng, K. T., Chang, H. C., Su, C-H. & Hsu, F-L., 1997, 於: Botanical Bulletin of Academia Sinica. 38, 4, p. 241-244 4 p.

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46 引文斯高帕斯（Scopus）

Identification of trans, trans-2,4-Decadienal metabolites in mouse and human cells using liquid chromatography-mass spectrometry

Pan, K. L., Huang, W. J., Hsu, M. H., Lee, H. L., Liu, H. J., Cheng, C. W., Tsai, M. H., Shen, M. Y. & Lin, P., 10月 20 2014, 於: Chemical Research in Toxicology. 27, 10, p. 1707-1719 13 p.

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8 引文斯高帕斯（Scopus）

Imatinib mesylate induction of ROS-dependent apoptosis in melanoma B16F0 cells

Chang, S. P., Shen, S. C., Lee, W. R., Yang, L-L. & Chen, Y. C., 6月 2011, 於: Journal of Dermatological Science. 62, 3, p. 183-191 9 p.

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32 引文斯高帕斯（Scopus）

Immobilized zinc affinity chromatography of pectin hydroxamic acids for purification of trypsin inhibitors from soybean and sweet potato

Liu, D. Z., Lu, Y. L., Cheng, H. C. & Hou, W. C., 12月 28 2005, 於: Journal of Agricultural and Food Chemistry. 53, 26, p. 10219-10223 5 p.

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8 引文斯高帕斯（Scopus）

Immuno-enhancement effects of Huang Qi Liu Yi Tang in a murine model of cyclophosphamide-induced leucopenia

Huang, G. C., Wu, L. S., Chen, L. G., Yang, L-L. & Wang, C. C., 1月 19 2007, 於: Journal of Ethnopharmacology. 109, 2, p. 229-235 7 p.

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39 引文斯高帕斯（Scopus）

Immunomodulatory activity of dioscorin, the storage protein of yam (Dioscorea alata cv. Tainong No. 1) tuber

Liu, Y. W., Shang, H. F., Wang, C. K., Hsu, F-L. & Hou, W. C., 11月 2007, 於: Food and Chemical Toxicology. 45, 11, p. 2312-2318 7 p.

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82 引文斯高帕斯（Scopus）

Immunomodulatory effects of hedysarum polybotrys extract in mice macrophages, splenocytes and leucopenia

Huang, G. C., Lee, C. J., Wang, K. T., Weng, B. C., Chien, T. Y., Tseng, S. H. & Wang, C. C., 12月 2013, 於: Molecules. 18, 12, p. 14862-14875 14 p.

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12 引文斯高帕斯（Scopus）

Immunostimulatory activities of yam tuber mucilages

Shang, H. F., Cheng, H. C., Liang, H. J., Liu, H. Y., Liu, S. Y. & Hou, W. C., 1月 2007, 於: Botanical Studies. 48, 1, p. 63-70 8 p.

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20 引文斯高帕斯（Scopus）

Imperatorin exerts antiallergic effects in Th2-mediated allergic asthma via induction of IL-10-producing regulatory T cells by modulating the function of dendritic cells

Lin, C. L., Hsiao, G., Wang, C. C. & Lee, Y. L., 8月 1 2016, 於: Pharmacological Research. 110, p. 111-121 11 p.

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33 引文斯高帕斯（Scopus）

Improved enamine-type addition of dehydroaporphine using microwave irradiation

Huang, W. J., Huang, C. C., Hsin, L. W., Tsai, Y. M., Lin, C. T., Lin, J. H. & Lee, S. S., 6月 9 2010, 於: Tetrahedron Letters. 51, 23, p. 3062-3064 3 p.

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2 引文斯高帕斯（Scopus）

Improving abnormal hemorheological parameters in aging guinea pigs by water-soluble extracts of Salvia miltiorrhiza Bunge

Hou, W. C., Tsay, H. S., Liang, H. J., Lee, T. Y., Wang, G. J. & Liu, D. Z., 5月 22 2007, 於: Journal of Ethnopharmacology. 111, 3, p. 483-489 7 p.

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15 引文斯高帕斯（Scopus）

Improving the stability of astaxanthin by microencapsulation in calcium alginate beads

Lin, S. F., Chen, Y. C., Chen, R. N., Chen, L. C., Ho, H. O., Tsung, Y. H., Sheu, M. T. & Liu, D. Z., 4月 1 2016, 於: PLoS One. 11, 4, e0153685.

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40 引文斯高帕斯（Scopus）

Incorporation of exudates of human platelet-rich fibrin gel in biodegradable fibrin scaffolds for tissue engineering of cartilage

Chien, C. S., Ho, H. O., Liang, Y. C., Ko, P. H., Sheu, M. T. & Chen, C. H., 5月 2012, 於: Journal of Biomedical Materials Research - Part B Applied Biomaterials. 100 B, 4, p. 948-955 8 p.

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48 引文斯高帕斯（Scopus）

Increase of β-endorphin secretion by syringin, an active principle of Eleutherococcus senticosus, to produce antihyperglycemic action in type 1-like diabetic rats

Niu, H. S., Hsu, F. L., Liu, I. M. & Cheng, J. T., 12月 2007, 於: Hormone and Metabolic Research. 39, 12, p. 894-898 5 p.

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19 引文斯高帕斯（Scopus）

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