生藥學研究所

研究成果

每年研究成果 1988 2003 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2023

• 22693 引文
• 68 h-指數
• 853 文章
• 7 評論/辯論
• 7 回顧型文獻
• 2 書籍
• 4 更多
  • 2 Erratum
  • 1 會議貢獻
  • 1 專利

每年研究成果

每年研究成果

搜尋結果

• 2023

  Antihyperglycemic and Anti-inflammatory Activities of Traditional Philippine Herbal Formula (Pito-pito)

  Ramos, J. L. T., Hsieh, C. Y., Lee, C. J., De Castro-Cruz, K. A. & Tsai, P. W., 2023, 於: Biointerface Research in Applied Chemistry. 13, 1, 99.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Philippines 100%
  • Antidiabetic Agent 95%
  • Glucosidases 88%
  • Antiinflammatory 74%
  • Hypoglycemic Agents 74%

• Biological Properties and Phytonutrient Profile of Beans: Vigna angularis, Vigna radiata, and Glycine max

  Hsieh, C. Y., Tsai, J. R., Lee, C. J., Ciou, Y. R., Li, J. S., Tayo, L. L. & Tsai, P. W., 2月 15 2023, 於: Biointerface Research in Applied Chemistry. 13, 1, 53.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Vigna 100%
  • Soybeans 77%
  • Tannin 76%
  • Proanthocyanidins 68%
  • Phytochemicals 68%
  1 引文 斯高帕斯（Scopus）
• 2022

  Acteoside exerts immunomodulatory effects on dendritic cells via aryl hydrocarbon receptor activation and ameliorates Th2-mediated allergic asthma by inducing Foxp3⁺ regulatory T cells

  Chang, J. H., Chuang, H. C., Hsiao, G., Hou, T. Y., Wang, C. C., Huang, S. C., Li, B. Y. & Lee, Y. L., 5月 2022, 於: International Immunopharmacology. 106, 108603.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • acteoside 100%
  • Aryl Hydrocarbon Receptors 77%
  • Regulatory T-Lymphocytes 60%
  • Dendritic Cells 54%
  • Asthma 47%
  1 引文 斯高帕斯（Scopus）

• A new angular naphthopyrone from feather star Comanthus parvicirrus (Müller, 1841)

  Ke, Z. Y., Chen, J. W., Wu, B. Y., Jhan, Y. Y., Wen, Z. H., Kung, T. A., Sung, P. J., Chen, J. J., Lai, K. H. & Chung, H. M., 4月 5 2022, 於: Journal of Molecular Structure. 1253, 132261.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • 2D NMR Spectrum 89%
  • Lipopolysaccharide 71%
  • Antiinflammatory 62%
  • Single Crystal X-Ray Diffraction 47%
  • Metabolite 46%

• A novel anti-tumor/anti-tumor-associated fibroblast/anti-mPEG tri-specific antibody to maximize the efficacy of mPEGylated nanomedicines against fibroblast-rich solid tumor

  Chen, M., Sheu, M. T., Cheng, T. L., Roffler, S. R., Lin, S. Y., Chen, Y. J., Cheng, Y. A., Cheng, J. J., Chang, H. Y., Wu, T. Y., Kao, A. P., Ho, Y. S. & Chuang, K. H., 1月 7 2022, 於: Biomaterials Science. 10, 1, p. 202-215 14 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Medical nanotechnology 100%
  • Fibroblasts 84%
  • Glycols 73%
  • Antibodies 73%
  • Doxorubicin 60%
  1 引文 斯高帕斯（Scopus）

• A universal in silico V(D)J recombination strategy for developing humanized monoclonal antibodies

  Hsieh, Y. C., Liao, J. M., Chuang, K. H., Ho, K. W., Hong, S. T., Liu, H. J., Huang, B. C., Chen, I. J., Liu, Y. L., Wang, J. Y., Tsai, H. L., Su, Y. C., Wang, Y. T. & Cheng, T. L., 12月 2022, 於: Journal of Nanobiotechnology. 20, 1, 58.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Monoclonal antibodies 100%
  • V(D)J Recombination 93%
  • Antibodies, Monoclonal, Humanized 83%
  • Computer Simulation 60%
  • Tumor Necrosis Factor-alpha 47%

• Bispecific T-cell engagers non-covalently decorated drug-loaded PEGylated nanocarriers for cancer immunochemotherapy

  Cheng, W. J., Chuang, K. H., Lo, Y. J., Chen, M., Chen, Y. J., Roffler, S. R., Ho, H. O., Lin, S. Y. & Sheu, M. T., 4月 2022, 於: Journal of Controlled Release. 344, p. 235-248 14 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • STA 9090 100%
  • Nanocarrier 57%
  • Glycol 49%
  • T-Lymphocytes 33%
  • Decoration 29%

• Discovery of a novel cyclin-dependent kinase 8 inhibitor with an oxindole core for anti-inflammatory treatment

  Lin, T. E., Yang, C. R., Chou, C. H., Hsu, J. Y., Chao, M. W., Sung, T. Y., Hsieh, J. H., Huang, W. J. & Hsu, K. C., 2月 2022, 於: Biomedicine and Pharmacotherapy. 146, 112459.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Cyclin-Dependent Kinase 8 100%
  • 2-oxindole 94%
  • Anti-Inflammatory Agents 38%
  • Inhibitory Concentration 50 23%
  • Inflammation 10%

• Efficacy and safety of Duhuo Jisheng Decoction add-on bisphosphonate medications in patients with osteoporosis: A meta-analysis of randomized controlled trials

  Huang, C. Y., Cheng, C. J., Chiou, W. F., Chang, W. C., Kang, Y. N. & Lee, M. H., 1月 30 2022, 於: Journal of Ethnopharmacology. 283, 114732.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Diphosphonates 51%
  • Osteoporosis 41%
  • Safety 40%
  • Meta-Analysis 35%
  • Randomized Controlled Trials 31%
  1 引文 斯高帕斯（Scopus）

• Endoplasmic Reticulum Stress of Oral Squamous Cell Carcinoma Induces Immunosuppression of Neutrophils

  Wu, C. F., Hung, T. T., Su, Y. C., Chen, P. J., Lai, K. H. & Wang, C. C., 3月 16 2022, 於: Frontiers in Oncology. 12, 818192.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Endoplasmic Reticulum Stress 100%
  • Immunosuppression 81%
  • Squamous Cell Carcinoma 74%
  • Neutrophils 70%
  • Conditioned Culture Medium 55%

• Identification of a dual FLT3 and MNK2 inhibitor for acute myeloid leukemia treatment using a structure-based virtual screening approach

  Yen, S. C., Chen, L. C., Huang, H. L., HuangFu, W. C., Chen, Y. Y., Eight Lin, T., Lien, S. T., Tseng, H. J., Sung, T. Y., Hsieh, J. H., Huang, W. J., Pan, S. L. & Hsu, K. C., 4月 2022, 於: Bioorganic Chemistry. 121, p. 105675 105675.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • fms-Like Tyrosine Kinase 3 100%
  • Acute Myeloid Leukemia 56%
  • Tyrosine 54%
  • Drug Resistance 15%
  • Eukaryotic Initiation Factor-4E 12%

• New ent-kaurene and germacrene derivatives from Mesona procumbens Hemseley and their biological activity

  Ganzon, J. G., Liaw, C. C., Lin, Y. C., Lin, Z. H., Wang, C. H., Chen, C. Y., Chuang, K. H. & Kuo, Y. H., 2022, (接受/付印) 於: Natural Product Research.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Platostoma palustre 100%
  • Kaurane Diterpenes 94%
  • Germacrene 93%
  • Ent-Kaurene 89%
  • Lamiaceae 77%

• Novel Two-Step Process in Cellulose Depolymerization: Hematite-Mediated Photocatalysis by Lytic Polysaccharide Monooxygenase and Fenton Reaction

  Wang, D., Kao, M-R., Li, J., Sun, P., Meng, Q., Vyas, A., Liang, P-H., Wang, Y-S. & Hsieh, Y. S. Y., 8月 2022, 於: Journal of Agricultural and Food Chemistry.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Monooxygenase Reaction 100%
  • photocatalysis 95%
  • hematite 87%
  • ferric oxide 75%
  • Fenton Reaction 72%

• O-methylated flavonol as a multi-kinase inhibitor of leukemogenic kinases exhibits a potential treatment for acute myeloid leukemia

  Yen, S. C., Wu, Y. W., Huang, C. C., Chao, M. W., Tu, H. J., Chen, L. C., Lin, T. E., Sung, T. Y., Tseng, H. J., Chu, J. C., Huang, W. J., Yang, C. R., HuangFu, W. C., Pan, S. L. & Hsu, K. C., 6月 2022, 於: Phytomedicine. 100, 154061.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • 3-hydroxyflavone 100%
  • Flavonol 87%
  • Flavonoid 63%
  • Acute Myeloid Leukemia 63%
  • Phosphotransferases 51%

• Pharmacokinetic Herb-Drug Interactions of Xiang-Sha-Liu-Jun-Zi-Tang and Paclitaxel in Male Sprague Dawley Rats and Its Influence on Enzyme Kinetics in Human Liver Microsomes

  Kapelemera, A. M., Uang, Y-S., Wang, L-H., Wu, T-Y., Lee, F-Y., Tai, L., Wang, C-C. & Lee, C-J., 2022, 於: Frontiers in Pharmacology. 13

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • liu-jun-zi-tang 100%
  • Herb-Drug Interactions 83%
  • Liver Microsomes 63%
  • Paclitaxel 56%
  • Sprague Dawley Rats 47%

• Predictive Model for Oral Status in Elderly People in a Taiwanese Nursing Home Using a High-Protein Black Soybean Koji Food

  Liao, K-W., Lo, W-L., Hsu, C-Y., Chiu, W-C., Wu, C-H., Chen, Y-W., Hsu, P-C. & Huang, H-Y., 4月 2022, 於: Frontiers in Nutrition. 9, p. 814315

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • nursing homes 100%
  • Soybean Proteins 89%
  • koji 89%
  • Nursing Homes 65%
  • cookies 51%

• Probing Anti-Leukemic Metabolites from Marine-Derived Streptomyces sp. LY1209

  Chen, Y-Y., Chen, L-Y., Chen, P-J., El-Shazly, M., Peng, B-R., Chen, Y-C., Su, C-H., Su, J-H., Sung, P-J., Yen, P-T., Wang, L-S. & Lai, K-H., 4月 2 2022, 於: Metabolites. 12, 4

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Diketopiperazines 100%
  • Streptomyces 70%
  • Antiproliferative 57%
  • Staurosporine 46%
  • Metabolite 40%

• Probiotic supplementation attenuates age-related sarcopenia via the gut–muscle axis in SAMP8 mice

  Chen, L. H., Chang, S. S., Chang, H. Y., Wu, C. H., Pan, C. H., Chang, C. C., Chan, C. H. & Huang, H. Y., 2月 2022, 於: Journal of Cachexia, Sarcopenia and Muscle.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Sarcopenia 100%
  • Probiotics 85%
  • Lactobacillus casei 62%
  • Muscles 48%
  • Hand Strength 18%
  2 引文 斯高帕斯（Scopus）

• Recent Advances in Bioutilization of Marine Macroalgae Carbohydrates: Degradation, Metabolism, and Fermentation

  Zheng, Y., Li, Y., Yang, Y., Zhang, Y., Wang, D., Wang, P., Wong, A. C. Y., Hsieh, Y. S. Y. & Wang, D., 1月 28 2022, 於: Journal of Agricultural and Food Chemistry.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Seaweed 100%
  • Carbohydrate Metabolism 80%
  • Fermentation 74%
  • macroalgae 70%
  • Polysaccharide 60%
  1 引文 斯高帕斯（Scopus）

• Vitisin A, a Resveratrol Tetramer, Improves Scopolamine-Induced Impaired Learning and Memory Functions in Amnesiac ICR Mice

  Chen, L. G., Wang, C. C., Lee, Y. S., Sie, Y. Y., Chang, C. I. & Hou, W. C., 2月 2022, 於: Biomedicines. 10, 2, 273.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • vitisin A 100%
  • malvidin-3-O-glucoside-4 vinyl 64%
  • Resveratrol 59%
  • Inbred ICR Mouse 59%
  • Scopolamine 57%
• 2021

  Achieving High Power Density and Long-Term Stable Flexible Triboelectric Nanogenerators through Surface Functionalization of High Work-Function Electrode with Cationic Thiol-Based Self-Assembled Monolayer

  Cheng, Y. H., Lee, C. J. & Chang, C. Y., 3月 2021, 於: Advanced Materials Technologies. 6, 3, 2000985.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Self assembled monolayers 100%
  • Nanogenerators 93%
  • Work Function 74%
  • Self Assembled Monolayer 62%
  • Surface Modification 55%
  2 引文 斯高帕斯（Scopus）

• Active Tumoral/Tumor Environmental Dual-Targeting by Non-Covalently Arming with Trispecific Antibodies or Dual-Bispecific Antibodies on Docetaxel-Loaded mPEGylated Nanocarriers to Enhance Chemotherapeutic Efficacy and Minimize Systemic Toxicity

  Cheng, W. J., Lin, S. Y., Chen, M., Chen, L. C., Ho, H. O., Chuang, K. H. & Sheu, M. T., 2021, 於: International Journal of Nanomedicine. 16, p. 4017-4030 14 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Bispecific Antibodies 100%
  • Antibodies 89%
  • Toxicity 83%
  • Docetaxel 79%
  • Nanocarrier 76%
  4 引文 斯高帕斯（Scopus）

• An electrostatically self-assembled fluorinated molecule as a surface modification layer for a high-performance and stable triboelectric nanogenerator

  Yang, J. R., Lee, C. J. & Chang, C. Y., 2月 2021, 於: Journal of Materials Chemistry A. 9, 7, p. 4230-4239 10 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Nanogenerators 100%
  • Surface treatment 71%
  • Molecules 66%
  • Surface Modification 58%
  • Dielectric Material 40%
  4 引文 斯高帕斯（Scopus）

• Anti-proliferative potential of secondary metabolites from the marine sponge theonella sp. Moving from correlation toward causation

  Lai, K. H., Peng, B. R., Su, C. H., El-Shazly, M., Sun, Y. L., Shih, M. C., Huang, Y. T., Yen, P. T., Wang, L. S. & Su, J. H., 8月 2021, 於: Metabolites. 11, 8, 532.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Theonella 100%
  • Porifera 54%
  • Antiproliferative 48%
  • Causality 44%
  • Macrolide Antibiotic Agent 33%
  2 引文 斯高帕斯（Scopus）

• A Pilot Study of Silymarin as Supplementation to Reduce Toxicities in Metastatic Colorectal Cancer Patients Treated With First-Line FOLFIRI Plus Bevacizumab

  Chang, T. K., Yin, T. C., Su, W. C., Tsai, H. L., Huang, C. W., Chen, Y. C., Li, C. C., Chen, P. J., Ma, C. J., Chuang, K. H., Cheng, T. L. & Wang, J. Y., 9月 2021, 於: Oncology Research. 28, 7, p. 801-809 9 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Silymarin 100%
  • Irinotecan 85%
  • Bevacizumab 81%
  • Colorectal Neoplasms 57%
  • Diarrhea 40%
  1 引文 斯高帕斯（Scopus）

• Arenarosides A-G, Polyhydroxylated Oleanane-Type Saponins from Polycarpaea arenaria and their Cytotoxic and Antiangiogenic Activities

  Nguyen, N. L., Vo, T. H., Lin, Y. C., Liaw, C. C., Lu, M. K., Cheng, J. J., Chen, M. C. & Kuo, Y. H., 2月 26 2021, 於: Journal of Natural Products. 84, 2, p. 259-267 9 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • oleanane 100%
  • Antiangiogenic 77%
  • Saponins 66%
  • Saponin 64%
  • Oleanolic Acid 55%
  3 引文 斯高帕斯（Scopus）

• Automatic detection of the circulating cell-free methylated DNA pattern of GCM2, ITPRIPL1 and CCDC181 for detection of early breast cancer and surgical treatment response

  Wang, S. C., Liao, L. M., Ansar, M., Lin, S. Y., Hsu, W. W., Su, C. M., Chung, Y. M., Liu, C. C., Hung, C. S. & Lin, R. K., 3月 2021, 於: Cancers. 13, 6, p. 1-26 26 p., 1375.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Cell-Free Nucleic Acids 100%
  • Breast Neoplasms 50%
  • Biomarkers 41%
  • Early Detection of Cancer 30%
  • Methylation 28%
  5 引文 斯高帕斯（Scopus）

• Brown Algae Carbohydrates: Structures, Pharmaceutical Properties, and Research Challenges

  Li, Y., Zheng, Y., Zhang, Y., Yang, Y., Wang, P., Imre, B., Wong, A. C. Y., Hsieh, Y. S. Y. & Wang, D., 10月 2021, 於: Marine Drugs. 19, 11

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Phaeophyta 100%
  • Pharmaceutical Research 90%
  • Brown 66%
  • Carbohydrates 56%
  • Carbohydrate 53%
  5 引文 斯高帕斯（Scopus）

• Butyrate modulates adipose-derived stem cells isolated from polygenic obese and diabetic mice to drive enhanced immunosuppression

  Hsu, W. T., Huang, W. J., Chiang, B. L. & Tseng, P. H., 7月 2021, 於: Cytotherapy. 23, 7, p. 567-581 15 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Butyrates 100%
  • Obese Mice 97%
  • Immunosuppression 72%
  • Stem Cells 58%
  • Immunosuppressive Agents 16%
  1 引文 斯高帕斯（Scopus）

• Compounds Isolated from Wikstroemia taiwanensis Regulate Bone Remodeling by Modulating Osteoblast and Osteoclast Activities

  Imtiyaz, Z., Lin, Y. T., Liang, F. Y., Chiou, W. F. & Lee, M. H., 7月 13 2021, 於: Frontiers in Pharmacology. 12, 670254.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Wikstroemia 100%
  • Osteoclasts 50%
  • Bone Remodeling 50%
  • Osteoblasts 46%
  • Osteoporosis 25%

• Constituents of aquilaria sinensis leaves upregulate the expression of matrix metalloproteases 2 and 9

  Hsiao, S. W., Wu, Y. C., Mei, H. C., Chen, Y. H., Hsiao, G. & Lee, C. K., 2021, 於: Molecules. 26, 9, 2537.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Pheophorbide A 100%
  • Thymelaeaceae 91%
  • Metalloproteases 54%
  • leaves 53%
  • Leaf Like Crystal 43%

• Determination of phenylalanine enantiomers in the plasma and urine of mammals and ᴅ-amino acid oxidase deficient rodents using two-dimensional high-performance liquid chromatography

  Hsiao, S-W., Ishii, C., Furusho, A., Hsieh, C-L., Shimizu, Y., Akita, T., Mita, M., Okamura, T., Konno, R., Ide, T., Lee, C-K. & Hamase, K., 1月 2021, 於: Biochimica et Biophysica Acta - Proteins and Proteomics. 1869, 1, p. 140540

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Phenylalanine 100%
  • Oxidoreductases 83%
  • Mammals 80%
  • Rodentia 75%
  • High Pressure Liquid Chromatography 74%
  3 引文 斯高帕斯（Scopus）

• Development of a simple fluorescence sensing system for carbonyl stress in urine

  Huang, W. J., Sun, Y. T., Lee, W. H., Lin, P. Y. & Chen, C. M., 2021, 於: Sensors and Materials. 33, 10, p. 3489-3497 9 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • urine 100%
  • Fluorescence 81%
  • Fluorescence Intensity 62%
  • 3-Deoxyglucosone 59%
  • High performance liquid chromatography 54%

• Dibenzofuran, 4-chromanone, acetophenone, and dithiecine derivatives: Cytotoxic constituents from eupatorium fortunei

  Chang, C. H., Wu, S., Hsu, K. C., Huang, W. J. & Chen, J. J., 7月 2021, 於: International journal of molecular sciences. 22, 14, 7448.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • 4-chromanone 100%
  • Ethenone 91%
  • Eupatorium 86%
  • dibenzofuran 82%
  • acetophenone 78%

• Downregulation of gap junctional intercellular communication and connexin 43 expression by bisphenol A in human granulosa cells

  Lin, T. C., Wang, K. H., Chuang, K. H., Kao, A. P. & Kuo, T. C., 6月 2021, 於: Biotechnology and Applied Biochemistry. 68, 3, p. 676-682 7 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • bisphenol A 100%
  • Connexin 43 94%
  • Granulosa Cells 91%
  • Bisphenol A 79%
  • Communication 70%
  3 引文 斯高帕斯（Scopus）

• Effect of 3-subsitution of quinolinehydroxamic acids on selectivity of histone deacetylase isoforms

  Mehndiratta, S., Chen, M. C., Chao, Y. H., Lee, C. H., Liou, J. P., Lai, M. J. & Lee, H. Y., 12月 2021, 於: Journal of Enzyme Inhibition and Medicinal Chemistry. 36, 1, p. 74-84 11 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Histone Deacetylases 100%
  • Apoptotic 98%
  • A549 Cells 94%
  • Histone 91%
  • Antiproliferative 85%

• Effects of Neurofeedback on Fibromyalgia: A Randomized Controlled Trial

  Wu, Y. L., Fang, S. C., Chen, S. C., Tai, C. J. & Tsai, P. S., 2021, (接受/付印) 於: Pain Management Nursing. 22, 6, p. 755-763 9 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Neurofeedback 100%
  • Fibromyalgia 82%
  • Randomized Controlled Trials 47%
  • Pain 40%
  • Alpha Rhythm 33%
  2 引文 斯高帕斯（Scopus）

• Efficacy of cinnamon patch treatment for alleviating symptoms of overactive bladder: A double-blind, randomized, placebo-controlled trial

  Chen, L. L., Shen, Y. C., Ke, C. C., Imtiyaz, Z., Chen, H. I., Chang, C. H. & Lee, M. H., 1月 2021, 於: Phytomedicine. 80, 153380.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Cinnamomum zeylanicum 100%
  • Overactive Urinary Bladder 85%
  • Safety 57%
  • Placebos 46%
  • Randomized Controlled Trials 45%
  4 引文 斯高帕斯（Scopus）

• Eps15 homology domain-containing protein 3 hypermethylation as a prognostic and predictive marker for colorectal cancer

  Wang, Y. H., Chang, S. C., Ansar, M., Hung, C. S. & Lin, R. K., 5月 2021, 於: Biomedicines. 9, 5, 453.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Protein Domains 100%
  • Marker 86%
  • Colorectal Neoplasms 78%
  • Protein 40%
  • Antimetabolite 29%

• Estrogenic and anti-neutrophilic inflammatory phenanthrenes from Juncus effusus L.

  Hu, H. C., Tsai, Y. H., Chuang, Y. C., Lai, K. H., Hsu, Y. M., Hwang, T. L., Lin, C. C., Fülöp, F., Wu, Y. C., Yu, S. Y., Kuo, Y. T. & Chang, F. R., 2021, (接受/付印) 於: Natural Product Research.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Phenanthrenes 100%
  • Juncus effusus 80%
  • phenanthrenes 66%
  • Tinnitus 58%
  • Chinese Traditional Medicine 54%
  1 引文 斯高帕斯（Scopus）

• Fast dereplication of xanthine oxidase-inhibiting compounds in alfalfa using comparative metabolomics

  Hsu, S. J., Verpoorte, R., Lin, S. M. & Lee, C. K., 3月 2021, 於: Food Research International. 141, 110170.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Medicago sativa 100%
  • Xanthine Oxidase 77%
  • xanthine oxidase 76%
  • Metabolomics 70%
  • metabolomics 65%
  5 引文 斯高帕斯（Scopus）

• Hydrolysable tannins exhibit acetylcholinesterase inhibitory and anti-glycation activities in vitro and learning and memory function improvements in scopolamine-induced amnesiac mice

  Chen, L. G., Lin, S. Y., Lee, Y. S., Wang, C. C. & Hou, W. C., 8月 2021, 於: Biomedicines. 9, 8, 1066.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Tellimagrandin I 100%
  • Hydrolyzable Tannins 76%
  • Hydrolysable Tannin 74%
  • tellimagrandin II 70%
  • Scopolamine 58%
  1 引文 斯高帕斯（Scopus）

• Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach

  Chao, M. W., Lin, T. E., HuangFu, W. C., Chang, C. D., Tu, H. J., Chen, L. C., Yen, S. C., Sung, T. Y., Huang, W. J., Yang, C. R., Pan, S. L. & Hsu, K. C., 12月 2021, 於: Journal of Enzyme Inhibition and Medicinal Chemistry. 36, 1, p. 98-108 11 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • % Inhibition 100%
  • Phosphotransferases 69%
  • Binding Site 63%
  • Drug 47%
  • Cell Cycle Resting Phase 27%

• In situ subcutaneously injectable thermosensitive PEG-PLGA diblock and PLGA-PEG-PLGA triblock copolymer composite as sustained delivery of bispecific anti-CD3 scFv T-cell/anti-EGFR Fab Engager (BiTEE)

  Wei, P. S., Chen, Y. J., Lin, S. Y., Chuang, K. H., Sheu, M. T. & Ho, H. O., 11月 2021, 於: Biomaterials. 278, 121166.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • poly(lactic-co-glycolic acid)-polyethylene glycol-poly(lactic-co-glycolic acid) 100%
  • Epidermal Growth Factor 82%
  • polyethylene glycol-poly(lactide-co-glycolide) 79%
  • T-cells 70%
  • Block copolymers 65%
  4 引文 斯高帕斯（Scopus）

• Interleukin-33 promotes invasiveness of human ovarian endometriotic stromal cells through the ST2/MAPK/MMP-9 pathway activated by 17β-estradiol

  Lin, T. C., Wang, K. H., Chuang, K. H., Kao, A. P. & Kuo, T. C., 7月 2021, 於: Taiwanese Journal of Obstetrics and Gynecology. 60, 4, p. 658-664 7 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Interleukin-33 100%
  • Matrix Metalloproteinase 9 78%
  • Stromal Cells 73%
  • Endometriosis 66%
  • Estrogen Receptors 19%

• Investigation of Selected Flavonoid Derivatives as Potent FLT3 Inhibitors for the Potential Treatment of Acute Myeloid Leukemia

  Yen, S. C., Chen, L. C., Huang, H. L., Ngo, S. T., Wu, Y. W., Lin, T. E., Sung, T. Y., Lien, S. T., Tseng, H. J., Pan, S. L., Huang, W. J. & Hsu, K. C., 1月 22 2021, 於: Journal of Natural Products. 84, 1, p. 1-10 10 p.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Flavonoids 100%
  • Flavonoid 94%
  • Acute Myeloid Leukemia 93%
  • Tyrosine 89%
  • Protein-Tyrosine Kinases 89%
  4 引文 斯高帕斯（Scopus）

• In vivo and in vitro evaluation of the osteogenic potential of Davallia mariesii T. Moore ex Baker

  Lin, Y. T., Peng, S. W., Imtiyaz, Z., Ho, C. W., Chiou, W. F. & Lee, M. H., 1月 10 2021, 於: Journal of Ethnopharmacology. 264, 113126.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Dimenhydrinate 100%
  • Osteogenic 80%
  • Connectivity Density 64%
  • Osteoporosis Treatment 61%
  • Estrogen 33%

• Isomalabaricane Triterpenes from the Marine Sponge Rhabdastrella sp

  Lai, K. H., Huang, Z. H., El-Shazly, M., Peng, B. R., Wei, W. C. & Su, J. H., 4月 6 2021, 於: Marine Drugs. 19, 4

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Triterpenes 100%
  • Triterpene 91%
  • Porifera 89%
  • Geodia 74%
  • Inhibitory Concentration 50 72%
  3 引文 斯高帕斯（Scopus）

• Lophatherum gracile Brongn. attenuates neutrophilic inflammation through inhibition of JNK and calcium

  Lai, K. H., Chen, P. J., Chen, C. C., Yang, S. H., El-Shazly, M., Chang, Y. C., Wu, Y. H., Wu, Y. H., Wang, Y. H., Hsieh, H. L. & Hwang, T. L., 1月 10 2021, 於: Journal of Ethnopharmacology. 264, 113224.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  • Antiinflammatory 100%
  • Calcium(0) 80%
  • Calcium 71%
  • Neutrophils 68%
  • Inflammation 61%
  6 引文 斯高帕斯（Scopus）

• Maternal immune activation causes social behavior deficits and hypomyelination in male rat offspring with an autism-like microbiota profile

  Lee, G. A., Lin, Y. K., Lai, J. H., Lo, Y. C., Yang, Y. C. S. H., Ye, S. Y., Lee, C. J., Wang, C. C., Chiang, Y. H. & Tseng, S. H., 8月 2021, 於: Brain Sciences. 11, 8, 1085.

  研究成果: 雜誌貢獻 › 文章 › 同行評審

  開啟存取

  • Social Behavior 100%
  • Autistic Disorder 85%
  • Microbiota 84%
  • Autism Spectrum Disorder 59%
  • Mothers 54%
  11 引文 斯高帕斯（Scopus）