生理學科

  • No. 250 Wu-Xing Street,

    11031 Taipei

研究成果 1989 2019

2019

Angiotensin-converting enzyme inhibitors or angiotensin receptor blocker monotherapy retard deterioration of renal function in Taiwanese chronic kidney disease population

Zheng, C. M., Wang, J. Y., Chen, T. T., Wu, Y. C., Wu, Y. L., Lin, H. T., Chiu, S. P., Chang, T. J., Zheng, J. Q., Chu, N. F., Lin, Y. M., Su, S. L., Lu, K. C., Chen, J. S., Sung, F. C., Lee, C. T., Yang, Y., Hwang, S. J., Wang, M. C., Hsu, Y. H. 及其他4, Chiou, H. Y., Kao, S., Wu, M. Y. & Lin, Y. F., 十二月 1 2019, 於 : Scientific Reports. 9, 1, 2694.

研究成果: 雜誌貢獻文章

開啟存取
Angiotensin Receptor Antagonists
Chronic Renal Insufficiency
Angiotensin-Converting Enzyme Inhibitors
Angiotensins
Kidney

Biocompatibility and osteogenic capacity of Mg-Zn-Ca Bulk metallic glass for rabbit tendon-bone interference fixation

Wong, C. C., Wong, P. C., Tsai, P. H., Jang, J. S. C., Cheng, C. K., Chen, H. H. & Chen, C. H., 五月 3 2019, 於 : International Journal of Molecular Sciences. 20, 9, 2191.

研究成果: 雜誌貢獻文章

開啟存取
tendons
Tendons
rabbits
Metallic glass
biocompatibility
2 引文 (Scopus)
Hypoxia-Inducible Factor 1
hypoxia
Autophagy
Chloramphenicol
Non-Small Cell Lung Carcinoma

ETF-QO Mutants Uncoupled Fatty Acid β-Oxidation and Mitochondrial Bioenergetics Leading to Lipid Pathology

Chokchaiwong, S., Kuo, Y-T., Hsu, S-P., Hsu, Y-C., Lin, S-H., Zhong, W-B., Lin, Y-F. & Kao, S-H., 一月 31 2019, 於 : Cells. 8, 2, p. 106

研究成果: 雜誌貢獻文章

Multiple Acyl Coenzyme A Dehydrogenase Deficiency
Acyl-CoA Dehydrogenase
Ubiquinone
Electron-Transferring Flavoproteins
Pathology

Folic acid inhibits colorectal cancer cell migration

Ting, P. C., Lee, W. R., Huo, Y. N., Hsu, S. P. & Lee, W. S., 一月 1 2019, 於 : Journal of Nutritional Biochemistry. 63, p. 157-164 8 p.

研究成果: 雜誌貢獻文章

Folic Acid
Cell Movement
Colorectal Neoplasms
Cells
Cell proliferation
1 引文 (Scopus)

Glycemia Lowering Effect of an Aqueous Extract of Hedychium coronarium Leaves in Diabetic Rodent Models

Tse, L. S., Liao, P. L., Tsai, C. H., Li, C. H., Liao, J. W., Kang, J. J. & Cheng, Y. W., 三月 14 2019, 於 : Nutrients. 11, 3

研究成果: 雜誌貢獻文章

開啟存取
Hedychium coronarium
Zingiberaceae
Type 2 Diabetes Mellitus
blood glucose
Rodentia
2 引文 (Scopus)

Homeostasis of glucose and lipid in non-alcoholic fatty liver disease

Chao, H. W., Chao, S. W., Lin, H., Ku, H. C. & Cheng, C. F., 一月 2 2019, 於 : International Journal of Molecular Sciences. 20, 2, 298.

研究成果: 雜誌貢獻回顧型文獻

homeostasis
liver
glucose
Liver
Lipids

Orexin-A Levels in Relation to the Risk of Metabolic Syndrome in Patients with Schizophrenia Taking Antipsychotics

Chen, P-Y., Chen, C-H., Chang, C-K., Kao, C-F., Lu, M-L., Lin, S-K., Huang, M-C., Hwang, L-L. & Mondelli, V., 一月 1 2019, 於 : International Journal of Neuropsychopharmacology. 22, 1, p. 28-36 9 p.

研究成果: 雜誌貢獻文章

Antipsychotic Agents
Schizophrenia
Clozapine
Metabolome
Odds Ratio
2 引文 (Scopus)

Post-injury neuroprotective effects of the thalidomide analog 3,6′-dithiothalidomide on traumatic brain injury

Batsaikhan, B., Wang, J. Y., Scerba, M. T., Tweedie, D., Greig, N. H., Miller, J. P., Hoffer, B. J., Lin, C. T. & Wang, J. Y., 二月 1 2019, 於 : International Journal of Molecular Sciences. 20, 3, 502.

研究成果: 雜誌貢獻文章

開啟存取
brain damage
Thalidomide
Neuroprotective Agents
Brain
analogs
Brain Concussion
Psychometrics
Longitudinal Studies
Sleep
Anxiety
1 引文 (Scopus)

SCUBE1-enhanced bone morphogenetic protein signaling protects against renal ischemia-reperfusion injury

Liao, W. J., Lin, H., Cheng, C. F., Ka, S. M., Chen, A. & Yang, R. B., 二月 1 2019, 於 : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1865, 2, p. 329-338 10 p.

研究成果: 雜誌貢獻文章

Bone Morphogenetic Proteins
Reperfusion Injury
Kidney
Ischemia
Reperfusion
開啟存取
Histone Deacetylase 1
Methylcholanthrene
Simvastatin
Renal Cell Carcinoma
Epithelial Cells
Lipolysis
Cyclic AMP-Dependent Protein Kinases
Adipocytes
Protein Kinases
Lipase
2018
16 引文 (Scopus)

(2R,6R)-hydroxynorketamine rescues chronic stress-induced depression-like behavior through its actions in the midbrain periaqueductal gray

Chou, D., Peng, H. Y., Lin, T. B., Lai, C. Y., Hsieh, M. C., Wen, Y. C., Lee, A. S., Wang, H. H., Yang, P. S., Chen, G. D. & Ho, Y. C., 九月 1 2018, 於 : Neuropharmacology. 139, p. 1-12 12 p.

研究成果: 雜誌貢獻文章

Periaqueductal Gray
Mesencephalon
Antidepressive Agents
Depression
AMPA Receptors
3 引文 (Scopus)

A synergistic anti-cancer effect of troglitazone and lovastatin in a human anaplastic thyroid cancer cell line and in a mouse xenograft model

Zhong, W. B., Tsai, Y. C., Chin, L. H., Tseng, J. H., Tang, L. W., Horng, S., Fan, Y. C. & Hsu, S. P., 七月 1 2018, 於 : International Journal of Molecular Sciences. 19, 7, 1834.

研究成果: 雜誌貢獻文章

troglitazone
Lovastatin
cultured cells
Heterografts
mice
3 引文 (Scopus)

Cardiovascular pressor effects of orexins in the dorsomedial hypothalamus

Li, T. L., Chen, J. Y. S., Huang, S. C., Dai, Y. W. E. & Hwang, L. L., 一月 5 2018, 於 : European Journal of Pharmacology. 818, p. 343-350 8 p.

研究成果: 雜誌貢獻文章

Hypothalamus
Orexin Receptors
Orexins
Dorsomedial Hypothalamic Nucleus
Arterial Pressure
2 引文 (Scopus)

Coenzyme Q10 serves to couple mitochondrial oxidative phosphorylation and fatty acid β-oxidation, and attenuates NLRP3 inflammasome activation

Chokchaiwong, S., Kuo, Y. T., Lin, S. H., Hsu, Y. C., Hsu, S. P., Liu, Y. T., Chou, A. J. & Kao, S. H., 一月 1 2018, (接受/付印) 於 : Free Radical Research.

研究成果: 雜誌貢獻文章

coenzyme Q10
Electron-Transferring Flavoproteins
Inflammasomes
Oxidative Phosphorylation
Ubiquinone

Composite polyelectrolyte multilayer and mesoporous bioactive glass nanoparticle coating on 316L stainless steel for controlled antibiotic release and biocompatibility

Liu, X., Chen, H. H., Lin, Y. C., Nabilla, S. C., Liu, W. C., Wang, W. C., Shih, S. J., Li, Y., Lin, C. P., Zhao, G. & Chung, R. J., 四月 1 2018, 於 : Journal of Biomedical Nanotechnology. 14, 4, p. 725-735 11 p.

研究成果: 雜誌貢獻文章

Bioactive glass
Stainless Steel
Antibiotics
Polyelectrolytes
Biocompatibility
2 引文 (Scopus)

Effects of female sex hormones on folic acid-induced anti-angiogenesis

Lee, W. S., Lu, Y. C., Kuo, C. T., Chen, C. T. & Tang, P. H., 一月 1 2018, (接受/付印) 於 : Acta Physiologica.

研究成果: 雜誌貢獻文章

Gonadal Steroid Hormones
Folic Acid
Umbilicus
Endothelial Cells
Estradiol Receptors
4 引文 (Scopus)

Expressions of chemokines and their receptors in the brain after heat stroke-induced cortical damage

Lin, Y. F., Liu, T. T., Hu, C. H., Chen, C. C. & Wang, J. Y., 一月 1 2018, (接受/付印) 於 : Journal of Neuroimmunology.

研究成果: 雜誌貢獻文章

Heat Stroke
Chemokine Receptors
Brain
Hot Temperature
Chemokines
3 引文 (Scopus)
Epithelial-Mesenchymal Transition
Renin-Angiotensin System
Streptozocin
Hyperglycemia
Gerbillinae
Experimental Diabetes Mellitus
Gerbillinae
Hyperglycemia
Lung
Pulmonary Fibrosis
2 引文 (Scopus)

Improved Synthesis of Unsymmetrical N-Aryl-N′-alkylpyridyl ß-Diketimines Using Molecular Sieves and their Lithium Complexes

Chand, K., Tsai, C. L., Chen, H. Y., Ching, W. M., Hsu, S. P., Carey, J. R. & Hsu, S. C. N., 三月 7 2018, 於 : European Journal of Inorganic Chemistry. 2018, 9, p. 1093-1098 6 p.

研究成果: 雜誌貢獻文章

Molecular sieves
Lithium
Ligands
Nuclear magnetic resonance
Purification
3 引文 (Scopus)

Intermittent hypoxia-generated ROS contributes to intracellular zinc regulation that limits ischemia/reperfusion injury in adult rat cardiomyocyte

Lien, C. F., Lee, W. S., Wang, I. C., Chen, T. I., Chen, T. L. & Yang, K. T., 五月 1 2018, 於 : Journal of Molecular and Cellular Cardiology. 118, p. 122-132 11 p.

研究成果: 雜誌貢獻文章

Reperfusion Injury
Cardiac Myocytes
Zinc
Reperfusion
Ischemia

Median nerve stimulation induces analgesia via orexininitiated endocannabinoid disinhibition in the periaqueductal gray

Chen, Y. H., Lee, H. J., Lee, M. T., Wu, Y. T., Lee, Y. H., Hwang, L. L., Hung, M. S., Zimmer, A., MacKie, K. & Chiou, L. C., 十一月 6 2018, 於 : Proceedings of the National Academy of Sciences of the United States of America. 115, 45, p. E10720-E10729

研究成果: 雜誌貢獻文章

Endocannabinoids
Periaqueductal Gray
Median Nerve
Analgesia
Cannabinoid Receptors
2 引文 (Scopus)
Phosphorylation
Cell proliferation
Progesterone
Stathmin
Cells
1 引文 (Scopus)
Tubulin Modulators
G2 Phase Cell Cycle Checkpoints
Colorectal Neoplasms
Apoptosis
Growth
2 引文 (Scopus)

Multiplex detection of urinary miRNA biomarkers by transmission surface plasmon resonance

Yeung, W. K., Chen, H. Y., Sun, J. J., Hsieh, T. H., Mousavi, M. Z., Chen, H. H., Lee, K. L., Lin, H., Wei, P. K. & Cheng, J. Y., 十月 7 2018, 於 : Analyst. 143, 19, p. 4715-4722 8 p.

研究成果: 雜誌貢獻文章

Surface Plasmon Resonance
Surface plasmon resonance
Biosensing Techniques
Biomarkers
MicroRNAs
15 引文 (Scopus)

Neuroprotective effects of pifithrin-α against traumatic brain injury in the striatum through suppression of neuroinflammation, oxidative stress, autophagy, and apoptosis

Huang, Y. N., Yang, L. Y., Greig, N. H., Wang, Y. C., Lai, C. C. & Wang, J. Y., 十二月 1 2018, 於 : Scientific Reports. 8, 1, 2368.

研究成果: 雜誌貢獻文章

Autophagy
Neuroprotective Agents
Oxidative Stress
Apoptosis
Corpus Striatum
7 引文 (Scopus)

Periaqueductal gray glutamatergic transmission governs chronic stress-induced depression

Ho, Y. C., Lin, T. B., Hsieh, M. C., Lai, C. Y., Chou, D., Chau, Y. P., Chen, G. D. & Peng, H. Y., 一月 1 2018, 於 : Neuropsychopharmacology. 43, 2, p. 302-312 11 p.

研究成果: 雜誌貢獻文章

Periaqueductal Gray
Glutamate Receptors
Depression
AMPA Receptors
Western Blotting
2 引文 (Scopus)

PMA inhibits endothelial cell migration through activating the PKC-δ/Syk/NF-κB-mediated up-regulation of Thy-1

Wen, H. C., Huo, Y. N., Chou, C. M. & Lee, W. S., 十二月 1 2018, 於 : Scientific Reports. 8, 1, 16247.

研究成果: 雜誌貢獻文章

Cell Movement
Acetates
Up-Regulation
Endothelial Cells
phorbol-12-myristate
Endothelial cells
Human Umbilical Vein Endothelial Cells
Progesterone
Up-Regulation
Protein Binding
1 引文 (Scopus)

Role of activating transcription factor 3 in fructose-induced metabolic syndrome in mice

Chou, C. L., Li, C. H., Lin, H., Liao, M. H., Wu, C. C., Chen, J. S., Sue, Y. M. & Fang, T. C., 八月 1 2018, 於 : Hypertension Research. 41, 8, p. 589-597 9 p.

研究成果: 雜誌貢獻文章

Activating Transcription Factor 3
Fructose
Knockout Mice
Diet
Blood Pressure

Role of the orexin 2 receptor in palatable-food consumption-associated cardiovascular reactivity in spontaneously hypertensive rats

Huang, S. C., Li, T. L., Lee, Y. H., Dai, Y. W. E., Chen, Y. C. & Hwang, L. L., 十二月 1 2018, 於 : Scientific Reports. 8, 1, 12703.

研究成果: 雜誌貢獻文章

Orexin Receptors
Inbred SHR Rats
Inbred WKY Rats
Food
Agar
2 引文 (Scopus)

Safety assessment of the Cistanche tubulosa health food product Memoregain®: Genotoxicity and 28-day repeated dose toxicity test

Liao, P. L., Li, C. H., Tse, L. S., Kang, J. J. & Cheng, Y. W., 八月 1 2018, 於 : Food and Chemical Toxicology. 118, p. 581-588 8 p.

研究成果: 雜誌貢獻文章

Cistanche
Toxicity Tests
Salmonella
health foods
safety assessment
3 引文 (Scopus)

Spinal TNF-α impedes Fbxo45-dependent Munc13-1 ubiquitination to mediate neuropathic allodynia in rats

Hsieh, M. C., Ho, Y. C., Lai, C. Y., Chou, D., Chen, G. D., Lin, T. B. & Peng, H. Y., 八月 1 2018, 於 : Cell Death and Disease. 9, 8, 811.

研究成果: 雜誌貢獻文章

Ubiquitination
Hyperalgesia
Tumor Necrosis Factor-alpha
Excitatory Postsynaptic Potentials
Wounds and Injuries

The CCL5/CCR5 Axis Promotes Vascular Smooth Muscle Cell Proliferation and Atherogenic Phenotype Switching

Lin, C. S., Hsieh, P. S., Hwang, L. L., Lee, Y. H., Tsai, S. H., Tu, Y. C., Hung, Y. W., Liu, C. C., Chuang, Y. P., Liao, M. T., Chien, S. & Tsai, M. C., 六月 1 2018, 於 : Cellular Physiology and Biochemistry. 47, 2, p. 707-720 14 p.

研究成果: 雜誌貢獻文章

Vascular Smooth Muscle
Smooth Muscle Myocytes
Cell Proliferation
Phenotype
High Fat Diet
2017
7 引文 (Scopus)
Aryl Hydrocarbon Receptors
Methylcholanthrene
Nitric Oxide Synthase Type III
Hypertension
Blood pressure
5 引文 (Scopus)

A GDF15 3′ UTR variant, rs1054564, results in allele-specific translational repression of GDF15 by hsa-miR-1233-3p

Teng, M. S., Hsu, L. A., Juan, S. H., Lin, W. C., Lee, M. C., Su, C. W., Wu, S. & Ko, Y. L., 八月 1 2017, 於 : PLoS One. 12, 8, e0183187.

研究成果: 雜誌貢獻文章

Growth Differentiation Factor 3
Growth Differentiation Factor 15
growth differentiation factors
3' Untranslated Regions
3' untranslated regions

ANALYSIS of INTERVERTEBRAL ANGULATIONS and MUSCULOSKELETAL SYMPTOMS of the SPINE in the MILITARY AIRCREWS of TAIWAN

Chen, H. H., Chung, C. H., Lee, C. C., Yang, C. S., Wen, Y. S., Lee, C. L. & Chiang, K. T., 四月 1 2017, 於 : Biomedical Engineering - Applications, Basis and Communications. 29, 2, 1750010.

研究成果: 雜誌貢獻文章

Spine
Neck
Articular Range of Motion
Surveys and Questionnaires
8 引文 (Scopus)

Antidepressants, sertraline and paroxetine, increase calcium influx and induce mitochondrial damage-mediated apoptosis of astrocytes

Then, C. K., Liu, K. H., Liao, M. H., Chung, K. H., Wang, J. Y. & Shen, S. C., 一月 1 2017, 於 : Oncotarget. 8, 70, p. 115490-115502 13 p.

研究成果: 雜誌貢獻文章

Sertraline
Paroxetine
Astrocytes
Antidepressive Agents
Apoptosis
14 引文 (Scopus)

Anti-inflammatory properties of shikonin contribute to improved early-stage diabetic retinopathy

Liao, P. L., Lin, C. H., Li, C. H., Tsai, C. H., Ho, J. D., Chiou, G. C. Y., Kang, J. J. & Cheng, Y. W., 三月 21 2017, 於 : Scientific Reports. 7, 44985.

研究成果: 雜誌貢獻文章

Diabetic Retinopathy
Anti-Inflammatory Agents
Retinal Pigments
Inbred C57BL Mouse
Glucose
8 引文 (Scopus)

Celastrol inhibits hepatitis C virus replication by upregulating heme oxygenase-1 via the JNK MAPK/Nrf2 pathway in human hepatoma cells

Tseng, C. K., Hsu, S. P., Lin, C. K., Wu, Y. H., Lee, J. C. & Young, K. C., 十月 1 2017, 於 : Antiviral Research. 146, p. 191-200 10 p.

研究成果: 雜誌貢獻文章

Heme Oxygenase-1
Virus Replication
Hepacivirus
Hepatocellular Carcinoma
Antiviral Agents
6 引文 (Scopus)

Circadian clock regulates hepatic polyploidy by modulating Mkp1-Erk1/2 signaling pathway

Chao, H. W., Doi, M., Fustin, J. M., Chen, H., Murase, K., Maeda, Y., Hayashi, H., Tanaka, R., Sugawa, M., Mizukuchi, N., Yamaguchi, Y., Yasunaga, J. I., Matsuoka, M., Sakai, M., Matsumoto, M., Hamada, S. & Okamura, H., 十二月 1 2017, 於 : Nature Communications. 8, 1, 2238.

研究成果: 雜誌貢獻文章

Mitogen-Activated Protein Kinase Phosphatases
Dual Specificity Phosphatase 1
Circadian Clocks
phosphatases
Polyploidy
12 引文 (Scopus)

Cytoplasmic aryl hydrocarbon receptor regulates glycogen synthase kinase 3 beta, accelerates vimentin degradation, and suppresses epithelial–mesenchymal transition in non-small cell lung cancer cells

Li, C. H., Liu, C. W., Tsai, C. H., Peng, Y. J., Yang, Y. H., Liao, P. L., Lee, C. C., Cheng, Y. W. & Kang, J. J., 五月 1 2017, 於 : Archives of Toxicology. 91, 5, p. 2165-2178 14 p.

研究成果: 雜誌貢獻文章

Glycogen Synthase Kinase 3
Aryl Hydrocarbon Receptors
Vimentin
Non-Small Cell Lung Carcinoma
Cells
3 引文 (Scopus)
Sensory Receptor Cells
Tumor Necrosis Factor-alpha
Lung
Cyclooxygenase 2
Neurons
18 引文 (Scopus)

L-Ascorbate Protects Against Methamphetamine-Induced Neurotoxicity of Cortical Cells via Inhibiting Oxidative Stress, Autophagy, and Apoptosis

Huang, Y. N., Yang, L. Y., Wang, J. Y., Lai, C. C., Chiu, C. T. & Wang, J. Y., 一月 1 2017, 於 : Molecular Neurobiology. 54, 1, p. 125-136 12 p.

研究成果: 雜誌貢獻文章

Methamphetamine
Autophagy
Oxidative Stress
Apoptosis
Ascorbic Acid
12 引文 (Scopus)
Peroxisome Proliferator-Activated Receptors
Epithelial-Mesenchymal Transition
Carnitine
Fibrosis
Kidney
8 引文 (Scopus)

Melatonin impedes Tet1-dependent mGluR5 promoter demethylation to relieve pain

Hsieh, M. C., Ho, Y. C., Lai, C. Y., Chou, D., Wang, H. H., Chen, G. D., Lin, T. B. & Peng, H. Y., 十一月 1 2017, 於 : Journal of Pineal Research. 63, 4, e12436.

研究成果: 雜誌貢獻文章

Metabotropic Glutamate 5 Receptor
Dioxygenases
Melatonin
Pain
Melatonin MT2 Receptor
2 引文 (Scopus)
imidazole mustard
Materials properties
Bone
Osseointegration
Monitoring