藥理學科

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Inhibitory effect of midazolam on MMP-9, MMP-1 and MMP-13 expression in PMA-stimulated human chondrocytes via recovery of NF-κB signaling

Wang, J. J., Huan, S. K. H., Hsieh, K. H., Chou, H. C., Hsiao, G., Jayakumar, T. & Sheu, J. R., 4月 2013, 於: Archives of Medical Science. 9, 2, p. 332-339 8 p.

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19 引文斯高帕斯（Scopus）

Inhibitory effect of PDGF-BB and serum-stimulated responses in vascular smooth muscle cell proliferation by hinokitiol via up-regulation of p21 and p53

Li, J-Y., Liu, C-P., Shiao, W-C., Jayakumar, T., Li, Y-S., Chang, N-C., Huang, S-Y. & Hsieh, C-Y., 1月 1 2018, 於: Archives of Medical Science. 14, 3, p. 579-587 9 p.

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14 引文斯高帕斯（Scopus）

Inhibitory effect of PMC, a potent hydrophilic α-tocopherol derivative, on vascular smooth muscle cell proliferation: The pivotal role of PKC-α translocation

Chang, C. C., Lee, J. J., Chiang, C-W., Jayakumar, T., Hsiao, G., Hsieh, C. Y. & Sheu, J. R., 8月 2010, 於: Pharmaceutical Biology. 48, 8, p. 938-946 9 p.

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7 引文斯高帕斯（Scopus）

Inhibitory Effects of an Orally Active Thromboxane A2 Receptor Antagonist, nstpbp5185, on Atherosclerosis in ApoE-Deficient Mice

Huang, S. W., Lien, J. C., Kuo, S. C. & Huang, T. F., 1月 1 2018, 於: Thrombosis and Haemostasis. 118, 2, p. 401-414 14 p.

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5 引文斯高帕斯（Scopus）

Inhibitory effects of flavonoids on phosphodiesterase isozymes from guinea pig and their structure-activity relationships

Ko, W-C., Shih, C. M., Lai, Y. H., Chen, J. H. & Huang, H. L., 11月 15 2004, 於: Biochemical Pharmacology. 68, 10, p. 2087-2094 8 p.

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133 引文斯高帕斯（Scopus）

Inhibitory effects of hesperetin derivatives on guinea pig phosphodiesterases and Their ratios between high- and low-affinity rolipram binding

Hsu, H. T., Wang, W. H., Han, C. Y., Chen, C. N., Chen, C. M. & Ko, W-C., 7月 2013, 於: Journal of Pharmaceutical Sciences. 102, 7, p. 2120-2127 8 p.

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6 引文斯高帕斯（Scopus）

Inhibitory effects of ketamine on lipopolysaccharide-induced microglial activation

Sheu, J. R., Chang, Y., Lee, J. J., Hsieh, C. Y., Hsiao, G. & Chou, D. S., 2009, 於: Mediators of Inflammation. 2009, 705379.

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77 引文斯高帕斯（Scopus）

Inhibitory effects of lycopene on in vitro platelet activation and in vivo prevention of thrombus formation

Hsiao, G., Wang, Y., Tzu, N. H., Fong, T. H., Shen, M. Y., Lin, K. H., Chou, D. S. & Sheu, J. R., 10月 2005, 於: Journal of Laboratory and Clinical Medicine. 146, 4, p. 216-226 11 p.

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34 引文斯高帕斯（Scopus）

Inhibitory effects of lycopene on the induction of NO, cytokines, and mitogen-activated protein kinase expression by lipopolysaccharide in primary cultured microglia

Shyu, K-G., Huang, W. C., Tai, P. A., Hsiao, G., Chou, D. S., Lee, L. W., Chen, J-S. & Sheu, J. R., 9月 2008, 於: Pharmaceutical Biology. 46, 9, p. 579-586 8 p.

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3 引文斯高帕斯（Scopus）

Inhibitory effects of quercetin derivatives on phosphodiesterase isozymes and high-affinity [³H]-rolipram binding in guinea pig tissues

Chan, A. L. F., Huang, H. L., Chien, H. C., Chen, C. M., Lin, C. N. & Ko, W. C., 10月 2008, 於: Investigational New Drugs. 26, 5, p. 417-424 8 p.

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24 引文斯高帕斯（Scopus）

Inhibitory mechanisms of activated matrix metalloproteinase-9 on platelet activation

Lee, Y. M., Lee, J. J., Shen, M. Y., Hsiao, G. & Sheu, J. R., 5月 10 2006, 於: European Journal of Pharmacology. 537, 1-3, p. 52-58 7 p.

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17 引文斯高帕斯（Scopus）

Inhibitory mechanisms of cme-1, a novel polysaccharide from the mycelia of cordyceps sinensis, in platelet activation

Chang, Y., Hsu, W. H., Lu, W. J., Jayakumar, T., Liao, J. C., Lin, M. J., Wang, S. H., Geraldine, P., Lin, K. H. & Sheu, J. R., 2015, 於: Current Pharmaceutical Biotechnology. 16, 5, p. 451-461 11 p.

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14 引文斯高帕斯（Scopus）

Inhibitory mechanisms of gabapentin, an antiseizure drug, on platelet aggregation

Pan, C. F., Shen, M. Y., Wu, C. J., Hsiao, G., Chou, D. S. & Sheu, J. R., 9月 2007, 於: Journal of Pharmacy and Pharmacology. 59, 9, p. 1255-1261 7 p.

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17 引文斯高帕斯（Scopus）

Inhibitory mechanisms of kinetin, a plant growth-promoting hormone, in platelet aggregation

Sheu, J. R., Hsiao, G., Shen, M. Y., Chou, C. Y., Lin, C. H., Chen, T-F., Chou, D. S. & Shen, J. R., 5月 2003, 於: Platelets. 14, 3, p. 189-196 8 p.

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16 引文斯高帕斯（Scopus）

Inhibitory mechanisms of low concentrations of oxidized low-density lipoprotein on platelet aggregation

Chou, D. S., Chan, C. H., Hsiao, G., Shen, M. Y., Tsai, Y. J., Chen, T-F. & Sheu, J. R., 5月 2006, 於: Journal of Biomedical Science. 13, 3, p. 333-343 11 p.

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5 引文斯高帕斯（Scopus）

Inhibitory Mechanisms of Metallothionein on Platelet Aggregation in in Vitro and Platelet Plug Formation in in Vivo Experiments

Sheu, J. R., Hsiao, G., Shen, M. Y., Wang, Y., Lin, K. H., Lin, C-H. & Chou, D. S., 12月 2003, 於: Experimental Biology and Medicine. 228, 11, p. 1321-1328 8 p.

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4 引文斯高帕斯（Scopus）

Inhibitory mechanisms of naloxone on human platelets

Sheu, J. R., Lee, Y. M., Lee, L. W., Luk, H. N. & Yen, M. H., 1998, 於: Clinical and Experimental Pharmacology and Physiology. 25, 7-8, p. 585-591 7 p.

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4 引文斯高帕斯（Scopus）

Inhibitory mechanisms of resveratrol in platelet activation: Pivotal roles of p38 MAPK and NO/cyclic GMP

Shen, M. Y., Hsiao, G., Liu, C. L., Fong, T. H., Lin, K. H., Chou, D. S. & Sheu, J. R., 11月 2007, 於: British Journal of Haematology. 139, 3, p. 475-485 11 p.

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127 引文斯高帕斯（Scopus）

Inhibitory mechanisms of tetramethylpyrazine in middle cerebral artery occlusion (MCAO)-induced focal cerebral ischemia in rats

Hsiao, G., Chen, Y. C., Lin, J. H., Lin, K. H., Chou, D. S., Lin, C-H. & Sheu, J. R., 4月 2006, 於: Planta Medica. 72, 5, p. 411-417 7 p.

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39 引文斯高帕斯（Scopus）

Inhibitory mechanisms of YC-1 and PMC in the induction of iNOS expression by lipoteichoic acid in RAW 264.7 macrophages

Hsiao, G., Huang, H. Y., Fong, T. H., Shen, M. Y., Lin, C. H., Teng, C. M. & Sheu, J. R., 4月 1 2004, 於: Biochemical Pharmacology. 67, 7, p. 1411-1419 9 p.

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31 引文斯高帕斯（Scopus）

Inhibitory signaling of 17β-estradiol in platelet activation: The pivotal role of cyclic AMP-mediated nitric oxide synthase activation

Wu, G-J., Lee, J. J., Chou, D-S., Jayakumar, T., Hsiao, G., Chen, W. F. & Sheu, J-R., 12月 15 2010, 於: European Journal of Pharmacology. 649, 1-3, p. 140-149 10 p.

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20 引文斯高帕斯（Scopus）

Integrin β3 and LKB1 are independently involved in the inhibition of proliferation by lovastatin in human intrahepatic cholangiocarcinoma

Yang, S. H., Lin, H. Y., Changou, C. A., Chen, C. H., Liu, Y. R., Wang, J., Jiang, X., Luh, F. & Yen, Y., 2016, 於: Oncotarget. 7, 1, p. 362-373 12 p.

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17 引文斯高帕斯（Scopus）

Interaction between daidzein and hesperetin on antispasmodic action in isolated sensitized and non-sensitized guinea-pig tracheas

Shih, C. H., Chang, T. Y. & Ko, W-C., 3月 29 2016, 於: Frontiers in Pharmacology. 7, MAR, 75.

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3 引文斯高帕斯（Scopus）

Interaction of thrombin-activated platelets with extracellular matrices (fibronectin and vitronectin): Comparison of the activity of Arg-Gly-Asp-containing venom peptides and monoclonal antibodies against glycoprotein IIb/IIIa complex

Sheu, J. R., Ko, W. C., Hung, W. C., Peng, H. C. & Huang, T. F., 1月 1997, 於: Journal of Pharmacy and Pharmacology. 49, 1, p. 78-84 7 p.

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10 引文斯高帕斯（Scopus）

Interleukin-6 induces vascular endothelial growth factor-C expression via Src-FAK-STAT3 signaling in lymphatic endothelial cells

Huang, Y. H., Yang, H. Y., Huang, S. W., Ou, G., Hsu, Y. F. & Hsu, M. J., 7月 1 2016, 於: PLoS One. 11, 7, e0158839.

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38 引文斯高帕斯（Scopus）

In-vitro and in-vivo antioxidant effects of the oyster mushroom Pleurotus ostreatus

Jayakumar, T., Thomas, P. A., Sheu, J. R. & Geraldine, P., 5月 2011, 於: Food Research International. 44, 4, p. 851-861 11 p.

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95 引文斯高帕斯（Scopus）

In vitro antioxidant and anticataractogenic potential of silver nanoparticles biosynthesized using an ethanolic extract of Tabernaemontana divaricata leaves

Anbukkarasi, M., Thomas, P. A., Sheu, J. R. & Geraldine, P., 7月 1 2017, 於: Biomedicine and Pharmacotherapy. 91, p. 467-475 9 p.

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20 引文斯高帕斯（Scopus）

Involvement of antioxidant defenses and nf-κb/erk signaling in anti-inflammatory effects of pterostilbene, a natural analogue of resveratrol

Jayakumar, T., Wu, M. P., Sheu, J. R., Hsia, C. H., Bhavan, P. S., Manubolu, M., Chung, C. L. & Hsia, C. H., 5月 2 2021, 於: Applied Sciences (Switzerland). 11, 10, 4666.

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5 引文斯高帕斯（Scopus）

Involvement of nuclear factor-κB in lipoteichoic acid-induced cyclooxygenase-2 expression in RAW 264.7 macrophages

Chiang, L. L., Kuo, C. T., Wang, C. H., Chen, T-F., Ho, Y. S., Kuo, H. P. & Lin, C. H., 1月 1 2003, 於: Journal of Pharmacy and Pharmacology. 55, 1, p. 115-123 9 p.

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17 引文斯高帕斯（Scopus）

Involvement of p38 MAPK phosphorylation and nitrate formation in aristolochic acid-mediated antiplatelet activity

Shen, M. Y., Liu, C. L., Hsiao, G., Liu, C. Y., Lin, K. H., Chou, D. S. & Sheu, J. R., 8月 2008, 於: Planta Medica. 74, 10, p. 1240-1245 6 p.

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10 引文斯高帕斯（Scopus）

Involvement of phosphatidylcholine-phospholipase C and protein kinase C in peptidoglycan-induced nuclear factor-κB activation and cyclooxygenase-2 expression in RAW 264.7 macrophages

Tzeng, J. I., Chen, B. C., Chang, H. M., Wang, J. J., Sureshbabu, M., Chien, M. H., Hsu, M. J., Bien, M. Y., Chiu, W. T., Hong, C. Y. & Lin, C. H., 2月 2010, 於: Pharmacological Research. 61, 2, p. 162-166 5 p.

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16 引文斯高帕斯（Scopus）

Involvement of protein kinase C-γ in IL-1β-induced cyclooxygenase-2 expression in human pulmonary epithelial cells

Lin, C. H., Sheu, S. Y., Lee, H. M., Ho, Y. S., Lee, W. S., Ko, W-C. & Sheu, J. R., 2000, 於: Molecular Pharmacology. 57, 1, p. 36-43 8 p.

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56 引文斯高帕斯（Scopus）

Involvement of the antiplatelet activity of magnesium sulfate in suppression of protein kinase C and the Na⁺/H⁺ exchanger

Hsiao, G., Shen, M. Y., Chou, D. S., Lin, C. H., Chen, T-F. & Sheu, J. R., 2004, 於: Journal of Biomedical Science. 11, 1, p. 19-26 8 p.

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15 引文斯高帕斯（Scopus）

Ir-6: A Novel Iridium (III) Organometallic Derivative for Inhibition of Human Platelet Activation

Shyu, R. S., Khamrang, T., Sheu, J. R., Hsia, C. W., Velusamy, M., Hsia, C. H., Chou, D. S. & Chang, C. C., 1月 1 2018, 於: Bioinorganic Chemistry and Applications. 2018, p. 8291393 8291393.

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2 引文斯高帕斯（Scopus）

Isoindoline scaffold-based dual inhibitors of HDAC6 and HSP90 suppressing the growth of lung cancer in vitro and in vivo

Ojha, R., Nepali, K., Chen, C. H., Chuang, K. H., Wu, T. Y., Lin, T. E., Hsu, K. C., Chao, M. W., Lai, M. J., Lin, M. H., Huang, H. L., Chang, C. D., Pan, S. L., Chen, M. C. & Liou, J. P., 3月 15 2020, 於: European Journal of Medicinal Chemistry. 190, 112086.

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17 引文斯高帕斯（Scopus）

Ketamine, a clinically used anesthetic, inhibits vascular smooth muscle cell proliferation via PP2A-activated PI3K/Akt/ERK inhibition

Chang, Y., Li, J. Y., Jayakumar, T., Hung, S. H., Lee, W. C., Manubolu, M., Sheu, J. R. & Hsu, M. J., 12月 1 2017, 於: International Journal of Molecular Sciences. 18, 12, 2545.

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10 引文斯高帕斯（Scopus）

Label-free multi-microfluidic immunoassays with liquid crystals on polydimethylsiloxane biosensing chips

Fan, Y. J., Chen, F. L., Liou, J. C., Huang, Y. W., Chen, C. H., Hong, Z. Y., Lin, J. D. & Hsiao, Y. C., 2月 1 2020, 於: Polymers. 12, 2, 395.

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23 引文斯高帕斯（Scopus）

Lack of effect of Z-butylidenephthalide on presynaptic N-type Ca²⁺ channels in isolated Guinea-pig ileum

Chen, M. & Ko, W. C., 2月 1 2016, 於: Naunyn-Schmiedeberg's Archives of Pharmacology. 389, 2, p. 159-166 8 p.

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6 引文斯高帕斯（Scopus）

Lanatoside C, a cardiac glycoside, acts through protein kinase Cδ to cause apoptosis of human hepatocellular carcinoma cells

Chao, M. W., Chen, T. H., Huang, H. L., Chang, Y. W., HuangFu, W. C., Lee, Y. C., Teng, C. M. & Pan, S. L., 4月 7 2017, 於: Scientific Reports. 7, 46134.

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29 引文斯高帕斯（Scopus）

Legionnaires' disease in a patient with rheumatoid arthritis

Chang, C. C., Chung, C. L., Huang, C-L. & Wang, F. C., 2001, 於: Journal of Microbiology, Immunology and Infection. 34, 1, p. 76-78 3 p.

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7 引文斯高帕斯（Scopus）

Length of stay and costs for asthma patients by hospital characteristics - A five-year population-based analysis

Lin, H. C., Kao, S., Wen, H. C., Chuan-Song, W. U. & Chung, C. L. I., 2005, 於: Journal of Asthma. 42, 7, p. 537-542 6 p.

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10 引文斯高帕斯（Scopus）

Leukocyte Cell-Derived Chemotaxin 2 Retards Non-Small Cell Lung Cancer Progression Through Antagonizing MET and EGFR Activities

Hung, W. Y., Chang, J. H., Cheng, Y., Chen, C. K., Chen, J. Q., Hua, K. T., Cheng, C. W., Hsiao, M., Chung, C. L., Lee, W. J. & Chien, M. H., 1月 1 2018, 於: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 51, 1, p. 337-355 19 p.

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10 引文斯高帕斯（Scopus）

Licochalcone A attenuates glioma cell growth in vitro and in vivo through cell cycle arrest

Lu, W. J., Wu, G. J., Chen, R. J., Chang, C. C., Lien, L. M., Chiu, C. C., Tseng, M. F., Huang, L. T. & Lin, K. H., 8月 1 2018, 於: Food and Function. 9, 8, p. 4500-4507 8 p.

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30 引文斯高帕斯（Scopus）

Licochalcone a prevents platelet activation and thrombus formation through the inhibition of PLCγ2-PKC, Akt, and MAPK pathways

Lien, L. M., Lin, K. H., Huang, L. T., Tseng, M. F., Chiu, H. C., Chen, R. J. & Lu, W. J., 7月 12 2017, 於: International Journal of Molecular Sciences. 18, 7, 1500.

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33 引文斯高帕斯（Scopus）

Lipoteichoic acid-induced cyclooxygenase-2 expression requires activations of p44/42 and p38 mitogen-activated protein kinase signal pathways

Lin, C. H., Kuan, I. H., Wang, C. H., Lee, H. M., Lee, W. S., Sheu, J. R., Hsiao, G., Wu, C. H. & Kuo, H. P., 8月 16 2002, 於: European Journal of Pharmacology. 450, 1, p. 1-9 9 p.

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21 引文斯高帕斯（Scopus）

Lipoteichoic acid upregulates plasminogen activator inhibitor-1 expression in parapneumonic effusions

Lee, K. L., Chen, W. L., Chen, R. J., Lai, K. S. & Chung, C. L., 1月 1 2018, 於: Respirology. 23, 1, p. 89-95 7 p.

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9 引文斯高帕斯（Scopus）

Long-term Fluorometholone Topical Use Induces Ganglion Cell Damage in Rats Analyzed With Optical Coherence Tomography

Lin, C. H., Liao, P. L., Hsiao, G., Li, C. H., Huang, S. H., Tsai, C. H., Wu, M. R., Lin, F. L., Ho, J. D., Cheng, H. W. & Cheng, Y. W., 10月 2015, 於: Toxicological Sciences. 147, 2, p. 317-325 9 p., kfv132.

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5 引文斯高帕斯（Scopus）

Lovastatin causes FaDu hypopharyngeal carcinoma cell death via AMPK-p63-survivin signaling cascade

Yen, C. S., Chen, J. C., Chang, Y. F., Hsu, Y. F., Chiu, P. T., Shiue, C., Chuang, Y. F., Ou, G. & Hsu, M. J., 4月 28 2016, 於: Scientific Reports. 6, 25082.

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19 引文斯高帕斯（Scopus）

Lovastatin-mediated MCF-7 cancer cell death involves LKB1-AMPK-p38MAPK-p53-survivin signalling cascade

Huang, S. W., Chyuan, I. T., Shiue, C., Yu, M. C., Hsu, Y. F. & Hsu, M. J., 1月 1 2020, 於: Journal of Cellular and Molecular Medicine. 24, 2, p. 1822-1836 15 p.

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32 引文斯高帕斯（Scopus）

Low concentration of oxidized low density lipoprotein suppresses platelet reactivity in vitro: An intracellular study

Chou, D. S., Hsiao, G., Shen, M. Y., Fong, T. H., Lin, C. H., Chen, T-F. & Sheu, J. R., 5月 2004, 於: Lipids. 39, 5, p. 433-440 8 p.

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5 引文斯高帕斯（Scopus）

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