每年研究計畫
指紋 查看啟用 藥物科學學科 的研究主題。這些主題標籤來自此機構會員的作品。共同形成了獨特的指紋。
Cells
Chemical Compounds
Histone Deacetylase Inhibitors
Medicine & Life Sciences
Neoplasms
Medicine & Life Sciences
Apoptosis
Medicine & Life Sciences
Inhibitory Concentration 50
Medicine & Life Sciences
Rats
Chemical Compounds
Histone Deacetylases
Medicine & Life Sciences
Derivatives
Chemical Compounds
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研究計畫 2010 2021
以參功能抗體或雙功能抗體非共價鍵合至負載 Docetaxel 與 Pictilisib 協同組合量比之聚乙二醇化奈米載體而賦予雙標靶與阻斷功效以用於惡性與轉移性乳癌治療之療效加乘與規避耐藥性(2/3)
8/1/19 → 7/1/20
研究計畫: A - 政府部門 › b - 科技部
研究成果 1985 2019
5
引文
(Scopus)
1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase
Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J. Y. & Liou, J. P., 一月 15 2019, 於 : European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.研究成果: 雜誌貢獻 › 文章
Benzamides
Histone Deacetylases
Tubulin
Heterografts
Inhibitory Concentration 50
Alteration of mesenchymal stem cells polarity by laminar shear stimulation promoting β-catenin nuclear localization
Chen, W-T., Hsu, W-T., Yen, M-H., Changou, C. A., Han, C-L., Chen, Y-J., Cheng, J-Y., Chang, T-H., Lee, O. K-S. & Ho, J. H-C., 一月 1 2019, 於 : Biomaterials. 190-191, p. 1-10 10 p.研究成果: 雜誌貢獻 › 文章
Catenins
Cell Polarity
Stem cells
Mesenchymal Stromal Cells
Shear stress
Amide-tethered quinoline-resorcinol conjugates as a new class of HSP90 inhibitors suppressing the growth of prostate cancer cells
Nepali, K., Lin, M. H., Chao, M. W., Peng, S. J., Hsu, K. C., Eight Lin, T., Chen, M. C., Lai, M. J., Pan, S. L. & Liou, J. P., 十月 1 2019, 於 : Bioorganic Chemistry. 91, 103119.研究成果: 雜誌貢獻 › 文章
Growth Inhibitors
Amides
Prostatic Neoplasms
Cells
Lead compounds