一般醫學學科

  • No. 250 Wu-Xing Street

    11031 Taipei

研究成果 1996 2019

2019

Alternative splicing in human cancer cells is modulated by the amiloride derivative 3,5-diamino-6-chloro-N-(N-(2,6-dichlorobenzoyl)carbamimidoyl)pyrazine-2-carboxide

Lee, C. C., Chang, W. H., Chang, Y. S., Yang, J. M., Chang, C. S., Hsu, K. C., Chen, Y. T., Liu, T. Y., Chen, Y. C., Lin, S. Y., Wu, Y. C. & Chang, J. G., 一月 1 2019, 於 : Molecular Oncology.

研究成果: 雜誌貢獻文章

開啟存取
Pyrazines
Amiloride
Alternative Splicing
Neoplasms
RNA Sequence Analysis
1 引文 (Scopus)
開啟存取
diabetes mellitus
Streptozocin
Medical problems
rats
Rats
2018
Dioscorea
Glucose Intolerance
dipeptides
Dipeptides
yams
3 引文 (Scopus)

Activation of Class I histone deacetylases contributes to mitochondrial dysfunction in cardiomyocytes with altered complex activities

Lkhagva, B., Kao, Y. H., Lee, T. I., Lee, T. W., Cheng, W. L. & Chen, Y. J., 五月 1 2018, (接受/付印) 於 : Epigenetics. p. 1-10 10 p.

研究成果: 雜誌貢獻文章

Histone Deacetylases
Cardiac Myocytes
Tumor Necrosis Factor-alpha
Adenosine Triphosphate
Enzymes
4 引文 (Scopus)

Aging modulates the substrate and triggers remodeling in atrial fibrillation

Lin, Y. K., Chen, Y. A., Lee, T. I., Chen, Y. C., Chen, S. A. & Chen, Y. J., 一月 1 2018, 於 : Circulation Journal. 82, 5, p. 1237-1244 8 p.

研究成果: 雜誌貢獻回顧型文獻

Atrial Fibrillation
Atrial Remodeling
Muscular Diseases
Comorbidity
Veins
4 引文 (Scopus)
docetaxel
Bispecific Antibodies
Lecithins
Drug Delivery Systems
Neoplasms
1 引文 (Scopus)
Receptor, Fibroblast Growth Factor, Type 1
Histone Deacetylases
Calcitriol
Muscle Cells
Fibroblast Growth Factor 1
1 引文 (Scopus)

Difference between observed and predicted glycated hemoglobin at baseline and treatment response to vildagliptin-based dual oral therapy in patients with type 2 diabetes

Wang, J. S., Hung, Y. J., Lu, Y. C., Tsai, C. L., Yang, W. S., Lee, T. I., Hsiao, Y. C. & Sheu, W. H. H., 四月 1 2018, 於 : Diabetes Research and Clinical Practice. 138, p. 119-127 9 p.

研究成果: 雜誌貢獻文章

Glycosylated Hemoglobin A
Type 2 Diabetes Mellitus
Fasting
Glucose
Therapeutics
1 引文 (Scopus)

Histone deacetylase inhibition of cardiac autophagy in rats on a high-fat diet with low-dose streptozotocin-induced type 2 diabetes mellitus

Lee, T. I., Bai, K. J., Chen, Y. C., Lee, T. W., Chung, C. C., Tsai, W. C., Tsao, S. Y. & Kao, Y. H., 一月 1 2018, 於 : Molecular Medicine Reports. 17, 1, p. 594-601 8 p.

研究成果: 雜誌貢獻文章

Histone Deacetylases
Autophagy
High Fat Diet
Nutrition
Streptozocin
1 引文 (Scopus)
Monocyte Chemoattractant Proteins
monocytes
suppressors
metastasis
Tumor Suppressor Genes
42 引文 (Scopus)

Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

Que, X., Hung, M. Y., Yeang, C., Gonen, A., Prohaska, T. A., Sun, X., Diehl, C., Määttä, A., Gaddis, D. E., Bowden, K., Pattison, J., MacDonald, J. G., Ylä-Herttuala, S., Mellon, P. L., Hedrick, C. C., Ley, K., Miller, Y. I., Glass, C. K., Peterson, K. L., Binder, C. J. 及其他2, Tsimikas, S. & Witztum, J. L., 六月 14 2018, 於 : Nature. 558, 7709, p. 301-306 6 p.

研究成果: 雜誌貢獻文章

Phospholipids
Macrophages
Atherosclerosis
Peritoneal Macrophages
Inflammation
1 引文 (Scopus)
Polyethyleneimine
Poly I-C
Gelatin
Antigens
Ovalbumin
1 引文 (Scopus)
Students
Education
Aptitude
Prescriptions
Curricula

ZFP36L1 and ZFP36L2 inhibit cell proliferation in a cyclin D-dependent and p53-independent manner

Suk, F-M., Chang, C-C., Lin, R-J., Lin, S-Y., Liu, S-C., Jau, C-F. & Liang, Y-C., 二月 9 2018, 於 : Scientific Reports. 8, 1, p. 2742

研究成果: 雜誌貢獻文章

Cyclin D
Cell Proliferation
Zinc Fingers
HCT116 Cells
Cyclin B
2017
5 引文 (Scopus)
Disintegrins
Calcitriol Receptors
Calcitriol
Metalloproteases
Cardiac Myocytes
1 引文 (Scopus)

Currarino syndrome: Presacral tumor mimicking Hirschsprung disease

Fu, Y. W., Hsu, Y. J. & Wei, C. H., 一月 1 2017, 於 : Formosan Journal of Surgery. 50, 1, p. 35-39 5 p.

研究成果: 雜誌貢獻文章

開啟存取
Hirschsprung Disease
Neoplasms
Laparotomy
Currarino triad
Neurogenic Urinary Bladder

Discrepant effects of heart failure on electrophysiological property in right ventricular outflow tract and left ventricular outflow tract cardiomyocytes

Lu, Y. Y., Cheng, C. C., Tsai, C. F., Lin, Y. K., Lee, T. I., Chen, Y. C., Chen, S. A. & Chen, Y. J., 六月 1 2017, 於 : Clinical Science. 131, 12, p. 1317-1327 11 p.

研究成果: 雜誌貢獻文章

Ownership
Cardiac Myocytes
Heart Failure
Action Potentials
Tail
2 引文 (Scopus)

Hot-Water Extracts from Roots of Vitis thunbergii var. taiwaniana and Identified ε-Viniferin Improve Obesity in High-Fat Diet-Induced Mice

Lu, Y. L., Lin, S. Y., Fang, S. U., Hsieh, Y. Y., Chen, C. R., Wen, C. L., Chang, C. I. & Hou, W. C., 三月 29 2017, 於 : Journal of Agricultural and Food Chemistry. 65, 12, p. 2521-2529 9 p.

研究成果: 雜誌貢獻文章

viniferins
Vitis
High Fat Diet
high fat diet
Nutrition
1 引文 (Scopus)

Intractable constipation in an adult with megarectosigmoid following repair of low-Type anorectal malformation

Hsu, Y. J., Fu, Y. W., Wei, C. H. & Chen, M. J., 一月 1 2017, 於 : Formosan Journal of Surgery. 50, 1, p. 40-43 4 p.

研究成果: 雜誌貢獻文章

開啟存取
Constipation
Enema
Loperamide
Hirschsprung Disease
Colitis
4 引文 (Scopus)

Modulation the alternative splicing of GLA (IVS4+919G>A) in Fabry disease

Chang, W. H., Niu, D. M., Lu, C. Y., Lin, S. Y., Liu, T. C. & Chang, J. G., 四月 1 2017, 於 : PLoS One. 12, 4, e0175929.

研究成果: 雜誌貢獻文章

Fabry Disease
Amiloride
alternative splicing
Alternative Splicing
Histone Code
15 引文 (Scopus)

PPARs modulate cardiac metabolism and mitochondrial function in diabetes

Lee, T. W., Bai, K. J., Lee, T. I., Chao, T. F., Kao, Y. H. & Chen, Y. J., 一月 10 2017, 於 : Journal of Biomedical Science. 24, 1, 5.

研究成果: 雜誌貢獻回顧型文獻

Diabetic Cardiomyopathies
Peroxisome Proliferator-Activated Receptors
Medical problems
Metabolism
Mitochondria

Primary Sjogren's syndrome and the risk of acute pancreatitis: A nationwide cohort study

Chang, C. C., Chang, Y. S., Wang, S. H., Lin, S. Y., Chen, Y. H. & Chen, J. H., 八月 1 2017, 於 : BMJ Open. 7, 8, e014807.

研究成果: 雜誌貢獻文章

Sjogren's Syndrome
Pancreatitis
Cohort Studies
Taiwan
Population

Rotura traqueal yatrogénica tras una intubación de urgencia

Chou, C. L., Lee, T. I. & Hu, T. Y., 二月 1 2017, 於 : Archivos de Bronconeumologia. 53, 2, p. 75-76 2 p.

研究成果: 雜誌貢獻文章

Intubation
Rupture
3 引文 (Scopus)
Thyroid Diseases
Thyrotropin
Autoimmune Diseases
Hashimoto Disease
Thyroidectomy
2016
10 引文 (Scopus)

Does enhanced diabetes management reduce the risk and improve the outcome of tuberculosis?

Lo, H. Y., Yang, S. L., Lin, H. H., Bai, K. J., Lee, J. J., Lee, T. I. & Chiang, C. Y., 三月 1 2016, 於 : International Journal of Tuberculosis and Lung Disease. 20, 3, p. 376-382 7 p.

研究成果: 雜誌貢獻文章

Risk Management
Diabetes Mellitus
Tuberculosis
National Health Programs
Incentive Reimbursement
8 引文 (Scopus)
Pulmonary Veins
Cardiac Myocytes
Fibroblast Growth Factor 1
Homeostasis
Sodium
9 引文 (Scopus)

Glucagon-like peptide-1 regulates calcium homeostasis and electrophysiological activities of HL-1 cardiomyocytes

Huang, J. H., Chen, Y. C., Lee, T. I., Kao, Y. H., Chazo, T. F., Chen, S. A. & Chen, Y. J., 四月 1 2016, 於 : Peptides. 78, p. 91-98 8 p.

研究成果: 雜誌貢獻文章

Glucagon-Like Peptide 1
Cardiac Myocytes
Homeostasis
Calcium
Ryanodine Receptor Calcium Release Channel
13 引文 (Scopus)
Diabetic Cardiomyopathies
Peroxisome Proliferator-Activated Receptors
Histone Deacetylases
Diabetes Mellitus
Fatty Acids

Iatrogenic tracheal rupture after emergent intubation

Chou, C. L., Lee, T. I. & Hu, T. Y., 2016, (接受/付印) 於 : Archivos de Bronconeumologia.

研究成果: 雜誌貢獻文章

Intubation
Rupture
1 引文 (Scopus)

Juvenile polyposis syndrome An unusual case report of anemia and gastrointestinal bleeding in young infant

Hsiao, Y. H., Wei, C. H., Chang, S. W., Chang, L., Fu, Y. W., Lee, H. C., Liu, H. L. & Yeung, C. Y., 一月 1 2016, 於 : Medicine (United States). 95, 37, e4550.

研究成果: 雜誌貢獻文章

開啟存取
Anemia
Polyps
Hemorrhage
Intussusception
Gastrointestinal Tract
1 引文 (Scopus)

Successful multivessel percutaneous coronary intervention for acute coronary syndrome in a HIV-positive severe haemophiliac

Chang, C. Y., Lin, S. Y., Tsai, J. R., Tsai, C. H. & Chen, Y. C., 九月 1 2016, 於 : Haemophilia. 22, 5, p. e481-e484

研究成果: 雜誌貢獻快報

Percutaneous Coronary Intervention
Acute Coronary Syndrome
HIV
5 引文 (Scopus)
Dioscorea
Dipeptidyl Peptidase 4
yams
glucose tolerance
Glucose Tolerance Test

翻轉教學應用於擬真臨床技能學習之滿意度初探

康以諾, 林哲瑋(Che-Wei L, 陳建宇(Jonathan C-Y C, 曾德銘(Te-Ming T & 吳建志(Chien-Chih W, 2016, 於 : 台灣擬真醫學教育期刊. 3, 1, p. 23-31 9 p.

研究成果: 雜誌貢獻文章

learning
classroom
student
manpower
medical student
2015
7 引文 (Scopus)

Bortezomib inhibits Burkitt's lymphoma cell proliferation by downregulating sumoylated hnRNP K and c-Myc expression

Suk, F. M., Lin, S. Y., Lin, R-J., Hsine, Y. H., Liao, Y. J., Fang, S. U. & Liang, Y. C., 2015, 於 : Oncotarget. 6, 28, p. 25988-26001 14 p.

研究成果: 雜誌貢獻文章

Heterogeneous-Nuclear Ribonucleoprotein K
Burkitt Lymphoma
Down-Regulation
Cell Proliferation
Molecular Weight
11 引文 (Scopus)
Macrophage Colony-Stimulating Factor
Extracellular Signal-Regulated MAP Kinases
Cytoplasmic and Nuclear Receptors
Osteogenesis
RANK Ligand

CanMEDS角色與醫學生臨床情境認知之相容性探究

唐功培, 康以諾, 何建志, 曾櫻枝, 林宗達, 林時宜 & 陳建宇, 2015, 於 : 中榮醫教. 18, p. 21-28 8 p.

研究成果: 雜誌貢獻文章

role expectation
medical student
scenario
communicator
incompatibility

Correction: Surface-enhanced Raman scattering on a silver film-modified Au nanoparticle-decorated SiO2 mask array

Chang, C. C., Chen, L. Y., Yang, K. H., Chen, Q. Y., Liang, Y. C., Lin, S. Y. & Liu, Y. C., 八月 12 2015, 於 : RSC Advances. 5, 86, p. 70501 1 p.

研究成果: 雜誌貢獻文章

Silver
Raman scattering
Masks
Nanoparticles
14 引文 (Scopus)
alpha-L-Fucosidase
Triple Negative Breast Neoplasms
Glycosylation
Down-Regulation
Survival
6 引文 (Scopus)
Ganoderma lucidum
solid state fermentation
feed additives
prebiotics
broiler chickens
6 引文 (Scopus)
4 引文 (Scopus)
Monophenol Monooxygenase
Melanins
Glycine
Down-Regulation
Agaricales
19 引文 (Scopus)

High anti-dengue virus activity of the OAS gene family is associated with increased severity of dengue

Simon-Loriere, E., Lin, R-J., Kalayanarooj, S. M., Chuansumrit, A., Casademont, I., Lin, S. Y., Yu, H. P., Lert-Itthiporn, W., Chaiyaratana, W., Tangthawornchaikul, N., Tangnararatchakit, K., Vasanawathana, S., Chang, B. L., Suriyaphol, P., Yoksan, S., Malasit, P., Despres, P., Paul, R., Lin, Y. L. & Sakuntabhai, A., 2015, 於 : Journal of Infectious Diseases. 212, 12, p. 2011-2020 10 p.

研究成果: 雜誌貢獻文章

Dengue Virus
Dengue
Genes
Virus Diseases
Antiviral Agents
17 引文 (Scopus)
Critical Care
Methicillin-Resistant Staphylococcus aureus
Intensive Care Units
Costs and Cost Analysis
Mortality
9 引文 (Scopus)

Increased risk of hepatocellular carcinoma in chronic hepatitis C patients with new onset diabetes: A nation-wide cohort study

Huang, Y. W., Wang, T. C., Yang, S. S., Lin, S. Y., Fu, S. C., Hu, J. T., Liu, C. J., Kao, J. H. & Chen, D. S., 十月 1 2015, 於 : Alimentary Pharmacology and Therapeutics. 42, 7, p. 902-911 10 p.

研究成果: 雜誌貢獻文章

Chronic Hepatitis C
Hepatocellular Carcinoma
Cohort Studies
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Mortality
9 引文 (Scopus)

Japanese Encephalitis Virus Nonstructural Protein NS5 Interacts with Mitochondrial Trifunctional Protein and Impairs Fatty Acid β-Oxidation

Kao, Y. T., Chang, B. L., Liang, J. J., Tsai, H. J., Lee, Y. L., Lin, R. J. & Lin, Y. L., 三月 1 2015, 於 : PLoS Pathogens. 11, 3, p. 1-26 26 p., e1004750.

研究成果: 雜誌貢獻文章

Mitochondrial Trifunctional Protein
Japanese Encephalitis Virus
Fatty Acids
Proteins
Cytokines
5 引文 (Scopus)

Managing mass events and competitions with difficult-to-access locations using mobile electrocardiac monitoring

Shih, C-M., Lin, C-W., Clinciu, D. L., Jian, W-S., Kuo, T. B. J., Nguyen, P. A., Usman, I., Hsu, C. K., Owili, P. O. & Li, Y-C., 四月 13 2015, (接受/付印) 於 : Computer Methods and Programs in Biomedicine. 121, 2, p. 109-115

研究成果: 雜誌貢獻文章

Wireless Technology
Emergencies
Monitoring
Cardiac Arrhythmias
Electrocardiography
7 引文 (Scopus)

N-hydroxycinnamide derivatives of osthole ameliorate hyperglycemia through activation of AMPK and p38 MAPK

Lee, W. H., Wu, H. H., Huang, W. J., Li, Y. N., Lin, R-J., Lin, S. Y. & Liang, Y. C., 三月 1 2015, 於 : Molecules. 20, 3, p. 4516-4529 14 p.

研究成果: 雜誌貢獻文章

hyperglycemia
AMP-Activated Protein Kinases
p38 Mitogen-Activated Protein Kinases
glucose
Hyperglycemia
2 引文 (Scopus)

Pheochromocytoma presenting as hyperglycemic hyperosmolar syndrome and unusual fever

Lee, I. S., Lee, T. W., Chang, C. J., Chien, Y. M. & Lee, T. I., 三月 3 2015, 於 : Internal and Emergency Medicine. 10, 6, p. 753-755 3 p.

研究成果: 雜誌貢獻文章

Hyperglycemic Hyperosmolar Nonketotic Coma
Adrenal Gland Neoplasms
Pheochromocytoma
Body Mass Index
Fever
10 引文 (Scopus)

Potential of vitamin D in treating diabetic cardiomyopathy

Lee, T. W., Lee, T. I., Chang, C. J., Lien, G. S., Kao, Y. H., Chao, T. F. & Chen, Y. J., 四月 1 2015, 於 : Nutrition Research. 35, 4, p. 269-279 11 p.

研究成果: 雜誌貢獻文章

Diabetic Cardiomyopathies
Vitamin D
Diabetes Mellitus
Cardiovascular Diseases
Hyperphosphatemia
2 引文 (Scopus)

Surface-enhanced Raman scattering on a silver film-modified Au nanoparticle-decorated SiO2 mask array

Chang, C. C., Chen, L. Y., Yang, K. H., Chen, Q. Y., Liang, Y. C., Lin, S. Y. & Liu, Y. C., 七月 23 2015, 於 : RSC Advances. 5, 81, p. 66096-66103 8 p.

研究成果: 雜誌貢獻文章

Silver
Raman scattering
Masks
Nanoparticles
Calcium