Additional file 2: of Monospecific antibody targeting of CDH11 inhibits epithelial-to-mesenchymal transition and represses cancer stem cell-like phenotype by up-regulating miR-335 in metastatic breast cancer, in vitro and in vivo



Table S1. Primers used for RT-qPCR in this study. Figure S1. Luciferase reporter assays. Human CDH11 3’UTR luciferase plasmid was transfected into both MCF7 and MDA-MB-231 cells for the test. The luciferase activity is a measurement of cdh11 mRNA transcripts. When miR-335 mimic molecules were transfected, the luciferase activity was significantly reduced while the opposite was true for the miR-335 inhibitor. Both MCF7 and MDA-MB-231 cells demonstrated the similar phenomenon. **p