Xanthomonas maltophilia bacteremia

An analysis of 32 cases

T. N. Jang, F. D. Wang, L. S. Wang, C. H. Liu, I. M. Liu

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

Thirty-two cases of Xanthomonas maltophilia bacteremia have been identified over the last two years at the Veterans General Hospital, Taipei. Among them, 27 cases (84%) were due to hospital-acquired infections, and 14 cases (44%) were polymicrobial bacteremia. One case was confirmed as prosthetic valve endocarditis and one case was complicated by recurrent attacks of ecthyma gangrenosum. Most cases had severe debilitating conditions. Twelve cases (38%) had a malignancy, 19 cases (59%) were resident in the Intensive Care Unit and 16 cases (50%) had undergone major surgery. The main predisposing factors included central venous catheterization, endotracheal intubation or tracheostomy, prior antibiotic therapy and prolonged hospitalization. Moxalactam, chloramphenicol and trimethoprim-sulfamethoxazole were the most effective agents in vitro against X. maltophilia. Twenty-two cases (69%) died during hospitalization; 13 cases (41%) were directly attributed to septicemia. Factors that adversely influenced mortality included inappropriate antimicrobial therapy and prior antibiotic treatment. Of particular interest is the fact that none of the patients who did not receive appropriate antimicrobial therapy survived. Early diagnosis and appropriate antibiotic therapy are critical for improving the prognosis of X. maltophilia infection.

Original languageEnglish
Pages (from-to)1170-1176
Number of pages7
JournalJournal of the Formosan Medical Association = Taiwan yi zhi
Volume91
Issue number12
Publication statusPublished - 1992
Externally publishedYes

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Stenotrophomonas maltophilia
Bacteremia
Anti-Bacterial Agents
Hospitalization
Ecthyma
Central Venous Catheterization
Moxalactam
Veterans Hospitals
Therapeutics
Intratracheal Intubation
Tracheostomy
Sulfamethoxazole Drug Combination Trimethoprim
Chloramphenicol
Cross Infection
Endocarditis
General Hospitals
Causality
Intensive Care Units
Early Diagnosis
Sepsis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Jang, T. N., Wang, F. D., Wang, L. S., Liu, C. H., & Liu, I. M. (1992). Xanthomonas maltophilia bacteremia: An analysis of 32 cases. Journal of the Formosan Medical Association = Taiwan yi zhi, 91(12), 1170-1176.

Xanthomonas maltophilia bacteremia : An analysis of 32 cases. / Jang, T. N.; Wang, F. D.; Wang, L. S.; Liu, C. H.; Liu, I. M.

In: Journal of the Formosan Medical Association = Taiwan yi zhi, Vol. 91, No. 12, 1992, p. 1170-1176.

Research output: Contribution to journalArticle

Jang, TN, Wang, FD, Wang, LS, Liu, CH & Liu, IM 1992, 'Xanthomonas maltophilia bacteremia: An analysis of 32 cases', Journal of the Formosan Medical Association = Taiwan yi zhi, vol. 91, no. 12, pp. 1170-1176.
Jang, T. N. ; Wang, F. D. ; Wang, L. S. ; Liu, C. H. ; Liu, I. M. / Xanthomonas maltophilia bacteremia : An analysis of 32 cases. In: Journal of the Formosan Medical Association = Taiwan yi zhi. 1992 ; Vol. 91, No. 12. pp. 1170-1176.
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