Xanthoma of the sacrum

Guo Shu Huang, Chih Wang Huang, Chian Her Lee, John A M Taylor, Chih Gueng Lin, Cheng Yu Chen

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Xanthoma is a lesion containing abundant foamy histiocytes most commonly occurring in superficial soft tissues such as skin, subcutis, or tendon sheaths. The involvement of deep skeletal structures, however, is rare and has only been infrequently reported in the English literature. Most xanthomas occur in patients with hyperlipidemic disorders. We report a case of a xanthoma in the sacrum and ilium of a patient with hyperlipidemia type IIa, who had chronic lower back pain for more than 20 years. On radiographs the lesion appeared multiloculated and osteolytic with a thin sclerotic border and containing multiple nodular calcifications within its matrix. Computed tomographic images revealed a presacral soft-tissue mass that also infiltrated the adjacent sacroiliac joint and iliac fossa. On histologic examination, abundant areas of xanthoma cells and cholesterol clefts, typical of xanthoma, were present. The patient received simple curettage of the lesion, and his symptoms were markedly relieved.

Original languageEnglish
Pages (from-to)674-678
Number of pages5
JournalSkeletal Radiology
Volume33
Issue number11
DOIs
Publication statusPublished - Nov 2004
Externally publishedYes

Fingerprint

Xanthomatosis
Sacrum
Ilium
Literature
Sacroiliac Joint
Histiocytes
Curettage
Low Back Pain
Hyperlipidemias
Tendons
Cholesterol
Skin

Keywords

  • CT
  • Hyperlipidemia
  • Ilium
  • Sacrum
  • Xanthoma

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Huang, G. S., Huang, C. W., Lee, C. H., Taylor, J. A. M., Lin, C. G., & Chen, C. Y. (2004). Xanthoma of the sacrum. Skeletal Radiology, 33(11), 674-678. https://doi.org/10.1007/s00256-004-0829-z

Xanthoma of the sacrum. / Huang, Guo Shu; Huang, Chih Wang; Lee, Chian Her; Taylor, John A M; Lin, Chih Gueng; Chen, Cheng Yu.

In: Skeletal Radiology, Vol. 33, No. 11, 11.2004, p. 674-678.

Research output: Contribution to journalArticle

Huang, GS, Huang, CW, Lee, CH, Taylor, JAM, Lin, CG & Chen, CY 2004, 'Xanthoma of the sacrum', Skeletal Radiology, vol. 33, no. 11, pp. 674-678. https://doi.org/10.1007/s00256-004-0829-z
Huang GS, Huang CW, Lee CH, Taylor JAM, Lin CG, Chen CY. Xanthoma of the sacrum. Skeletal Radiology. 2004 Nov;33(11):674-678. https://doi.org/10.1007/s00256-004-0829-z
Huang, Guo Shu ; Huang, Chih Wang ; Lee, Chian Her ; Taylor, John A M ; Lin, Chih Gueng ; Chen, Cheng Yu. / Xanthoma of the sacrum. In: Skeletal Radiology. 2004 ; Vol. 33, No. 11. pp. 674-678.
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