Women with endometriosis have higher comorbidities: Analysis of domestic data in Taiwan

Sen Wen Teng, Huann Cheng Horng, Chi Hong Ho, Ming Shyen Yen, Hsiang Tai Chao, Peng Hui Wang, Yen Hou Chang, Yi Chang, Kuan Chong Chao, Yi Jen Chen, Chi Mu Chuang, Yu Chen Huang, Ling Yu Jiang, Hsin Yang Li, Chia Hao Liu, Pi Lin Sun, Kuo Chang Wen, Hua Hsi Wu, Hann Chin Yu, Fong Yuan JuChih Ping Tsai, Wen Hsun Chang, Yen Mei Hsu, Shu Yun Huang, Na Rong Lee, Chih Yao Chen, Ting Chen Chang, Wen Chun Chang, Chii Hou Chen, Ruey Jian Chen, Song Nan Chow, Yih Ron Lien, Bor Ching Sheu, Pao Ling Torng, Men Luh Yen, Wen Ling Lee, Kuan Chin Wang, Chih Long Chang, Chih Ping Chen, Jen Ruei Chen, Tze Chien Chen, Jian Pei Huang, Ming Chao Huang, Yeou Lih Wang, Cheng Chang Chang, Jah Yao Liu, Her Young Su, Yu Chi Wang, Mu Hsien Yu, Ching Chuang Chu, Lee Wen Huang, Kok Min Seow, Tsung Hsuan Lai, Fa Kung Lee, Chii Hou Chen, Wei-Min Liu, Jyh Shin Chiou, Ben Shian Huang, Yen Feng Lu, Sheng Mou Hsiao, Hsu Dong Sun, Wen Yih Wu, Kuo Hu Chen, Jeng Hsiu Hung, Hung-Cheng Lai, Chiou-Chung Yuan, Ching Hung Hsieh, Chin Jung Wang, Chia Hao Chan, Shing Jyh Chang, Chuan Chi Shih, Man Jung Hung, Shih Tien Hsu, Yu Min Ke, Chien Hsing Lu, Lou Sun, Wei Chun Chang, Yao Ching Hung, Wu Chou Lin, Po Hui Wang, Tze Ho Chen, Yiu Tai Li, Meng Hsing Wu, Kuo Feng Huang, Fei Chi Chuang, Hung Chun Fu, Fu Tsai Kung, Kuan Hui Huang, San Nung Chen, An Jen Chiang, Ju Yueh Li, Li Te Lin, Hsiao Wen Tsai, Kuan Hao Tsui

Research output: Contribution to journalReview article

26 Citations (Scopus)

Abstract

Endometriosis, defined by the presence of viable extrauterine endometrial glands and stroma, can grow or bleed cyclically, and possesses characteristics including a destructive, invasive, and metastatic nature. Since endometriosis may result in pelvic inflammation, adhesion, chronic pain, and infertility, and can progress to biologically malignant tumors, it is a long-term major health issue in women of reproductive age. In this review, we analyze the Taiwan domestic research addressing associations between endometriosis and other diseases. Concerning malignant tumors, we identified four studies on the links between endometriosis and ovarian cancer, one on breast cancer, two on endometrial cancer, one on colorectal cancer, and one on other malignancies, as well as one on associations between endometriosis and irritable bowel syndrome, one on links with migraine headache, three on links with pelvic inflammatory diseases, four on links with infertility, four on links with obesity, four on links with chronic liver disease, four on links with rheumatoid arthritis, four on links with chronic renal disease, five on links with diabetes mellitus, and five on links with cardiovascular diseases (hypertension, hyperlipidemia, etc.). The data available to date support that women with endometriosis might be at risk of some chronic illnesses and certain malignancies, although we consider the evidence for some comorbidities to be of low quality, for example, the association between colon cancer and adenomyosis/endometriosis. We still believe that the risk of comorbidity might be higher in women with endometriosis than that we supposed before. More research is needed to determine whether women with endometriosis are really at risk of these comorbidities.

Original languageEnglish
Pages (from-to)577-582
Number of pages6
JournalJournal of the Chinese Medical Association
Volume79
Issue number11
DOIs
Publication statusPublished - Nov 1 2016

Keywords

  • comorbidity
  • endometriosis
  • Taiwan

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Teng, S. W., Horng, H. C., Ho, C. H., Yen, M. S., Chao, H. T., Wang, P. H., Chang, Y. H., Chang, Y., Chao, K. C., Chen, Y. J., Chuang, C. M., Huang, Y. C., Jiang, L. Y., Li, H. Y., Liu, C. H., Sun, P. L., Wen, K. C., Wu, H. H., Yu, H. C., ... Tsui, K. H. (2016). Women with endometriosis have higher comorbidities: Analysis of domestic data in Taiwan. Journal of the Chinese Medical Association, 79(11), 577-582. https://doi.org/10.1016/j.jcma.2016.04.006