Why Is the Distinction between Neural Predispositions, Prerequisites, and Correlates of the Level of Consciousness Clinically Relevant?: Functional Brain Imaging in Coma and Vegetative State

G. Northoff, Wolf Dieter Heiss

Research output: Contribution to journalArticle

7 Citations (Scopus)
Original languageEnglish
Pages (from-to)1147-1151
Number of pages5
JournalStroke
Volume46
Issue number4
DOIs
Publication statusPublished - 2015

Keywords

  • coma
  • functional magnetic resonance imaging
  • neural predispositions
  • positron emission tomography
  • 4 aminobutyric acid A receptor
  • oxygen 15
  • brain depth stimulation
  • consciousness
  • consciousness level
  • correlational study
  • disease predisposition
  • electroencephalogram
  • functional neuroimaging
  • glucose metabolism
  • human
  • persistent vegetative state
  • priority journal
  • Review
  • metabolism
  • pathophysiology
  • procedures
  • Coma
  • Functional Neuroimaging
  • Humans
  • Persistent Vegetative State

Cite this

@article{8c0b3ad02280467e8ab3ad9dc000b248,
title = "Why Is the Distinction between Neural Predispositions, Prerequisites, and Correlates of the Level of Consciousness Clinically Relevant?: Functional Brain Imaging in Coma and Vegetative State",
keywords = "coma, functional magnetic resonance imaging, neural predispositions, positron emission tomography, 4 aminobutyric acid A receptor, oxygen 15, brain depth stimulation, consciousness, consciousness level, correlational study, disease predisposition, electroencephalogram, functional neuroimaging, glucose metabolism, human, persistent vegetative state, priority journal, Review, metabolism, pathophysiology, procedures, Coma, Functional Neuroimaging, Humans, Persistent Vegetative State",
author = "G. Northoff and Heiss, {Wolf Dieter}",
note = "Export Date: 11 May 2016 CODEN: SJCCA Correspondence Address: Northoff, G.; Department of Neuroscience and Mental Health, University of Ottawa Institute of Mental Health Research, 1145 Carling Ave, Canada Chemicals/CAS: oxygen 15, 13982-43-9 References: Gosseries, O., Di, H., Laureys, S., Boly, M., Measuring consciousness in severely damaged brains (2014) Annu Rev Neurosci, 37, pp. 457-478; Giacino, J.T., Fins, J.J., Laureys, S., Schiff, N.D., Disorders of consciousness after acquired brain injury: The state of the science (2014) Nat Rev Neurol, 10, pp. 99-114; Schnakers, C., Vanhaudenhuyse, A., Giacino, J., Ventura, M., Boly, M., Majerus, S., Diagnostic accuracy of the vegetative and minimally conscious state: Clinical consensus versus standardized neurobehavioral assessment (2009) BMC Neurol, 9, p. 35; Kampfl, A., Schmutzhard, E., Franz, G., Pfausler, B., Haring, H.P., Ulmer, H., Prediction of recovery from post-traumatic vegetative state with cerebral magnetic-resonance imaging (1998) Lancet, 351, pp. 1763-1767; Northoff, G., What the brain's intrinsic activity can tell us about consciousness? A tri-dimensional view (2013) Neurosci Biobehav Rev, 37, pp. 726-738; Northoff, G., (2014) Unlocking the Brain: Volume 1: Coding, , Oxford, New York: Oxford University Press; Northoff, G., (2014) Unlocking the Brain. Volume 2: Consciousness; Heiss, W.D., Gerstenbrand, F., Prosenz, P., Krenn, J., The prognostic value of cerebral blood flow measurement in patients with the apallic syndrome (1972) J Neurol Sci, 16, pp. 373-382; Oder, W., Goldenberg, G., Podreka, I., Deecke, L., HM-PAO-SPECT in persistent vegetative state after head injury: Prognostic indicator of the likelihood of recovery? (1991) Intensive Care Med, 17, pp. 149-153; Bergsneider, M., Hovda, D.A., Shalmon, E., Kelly, D.F., Vespa, P.M., Martin, N.A., Cerebral hyperglycolysis following severe traumatic brain injury in humans: A positron emission tomography study (1997) J Neurosurg, 86, pp. 241-251; Heiss, W.D., PET in coma and in vegetative state (2012) Eur J Neurol, 19, pp. 207-211; Laureys, S., Schiff, N.D., Coma and consciousness: Paradigms (re)framed by neuroimaging (2012) Neuroimage, 61, pp. 478-491; Stender, J., Gosseries, O., Bruno, M.A., Charland-Verville, V., Vanhaudenhuyse, A., Demertzi, A., Diagnostic precision of PET imaging and functional MRI in disorders of consciousness: A clinical validation study (2014) Lancet, 384, pp. 514-522; Laureys, S., Owen, A.M., Schiff, N.D., Brain function in coma, vegetative state, and related disorders (2004) Lancet Neurol, 3, pp. 537-546; Vanhaudenhuyse, A., Noirhomme, Q., Tshibanda, L.J., Bruno, M.A., Boveroux, P., Schnakers, C., Default network connectivity reflects the level of consciousness in non-communicative brain-damaged patients (2010) Brain, 133, pp. 161-171; Huang, Z., Dai, R., Wu, X., Yang, Z., Liu, D., Hu, J., The self and its resting state in consciousness: An investigation of the vegetative state (2014) Hum Brain Mapp, 35, pp. 1997-2008; Boly, M., Faymonville, M.E., Peigneux, P., Lambermont, B., Damas, P., Del Fiore, G., Auditory processing in severely brain injured patients: Differences between the minimally conscious state and the persistent vegetative state (2004) Arch Neurol, 61, pp. 233-238; Monti, M.M., Vanhaudenhuyse, A., Coleman, M.R., Boly, M., Pickard, J.D., Tshibanda, L., Willful modulation of brain activity in disorders of consciousness (2010) N Engl J Med, 362, pp. 579-589; Qin, P., Di, H., Liu, Y., Yu, S., Gong, Q., Duncan, N., Anterior cingulate activity and the self in disorders of consciousness (2010) Hum Brain Mapp, 31, pp. 1993-2002",
year = "2015",
doi = "10.1161/STROKEAHA.114.007969",
language = "English",
volume = "46",
pages = "1147--1151",
journal = "Stroke",
issn = "0039-2499",
publisher = "Lippincott Williams and Wilkins",
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TY - JOUR

T1 - Why Is the Distinction between Neural Predispositions, Prerequisites, and Correlates of the Level of Consciousness Clinically Relevant?: Functional Brain Imaging in Coma and Vegetative State

AU - Northoff, G.

AU - Heiss, Wolf Dieter

N1 - Export Date: 11 May 2016 CODEN: SJCCA Correspondence Address: Northoff, G.; Department of Neuroscience and Mental Health, University of Ottawa Institute of Mental Health Research, 1145 Carling Ave, Canada Chemicals/CAS: oxygen 15, 13982-43-9 References: Gosseries, O., Di, H., Laureys, S., Boly, M., Measuring consciousness in severely damaged brains (2014) Annu Rev Neurosci, 37, pp. 457-478; Giacino, J.T., Fins, J.J., Laureys, S., Schiff, N.D., Disorders of consciousness after acquired brain injury: The state of the science (2014) Nat Rev Neurol, 10, pp. 99-114; Schnakers, C., Vanhaudenhuyse, A., Giacino, J., Ventura, M., Boly, M., Majerus, S., Diagnostic accuracy of the vegetative and minimally conscious state: Clinical consensus versus standardized neurobehavioral assessment (2009) BMC Neurol, 9, p. 35; Kampfl, A., Schmutzhard, E., Franz, G., Pfausler, B., Haring, H.P., Ulmer, H., Prediction of recovery from post-traumatic vegetative state with cerebral magnetic-resonance imaging (1998) Lancet, 351, pp. 1763-1767; Northoff, G., What the brain's intrinsic activity can tell us about consciousness? A tri-dimensional view (2013) Neurosci Biobehav Rev, 37, pp. 726-738; Northoff, G., (2014) Unlocking the Brain: Volume 1: Coding, , Oxford, New York: Oxford University Press; Northoff, G., (2014) Unlocking the Brain. Volume 2: Consciousness; Heiss, W.D., Gerstenbrand, F., Prosenz, P., Krenn, J., The prognostic value of cerebral blood flow measurement in patients with the apallic syndrome (1972) J Neurol Sci, 16, pp. 373-382; Oder, W., Goldenberg, G., Podreka, I., Deecke, L., HM-PAO-SPECT in persistent vegetative state after head injury: Prognostic indicator of the likelihood of recovery? (1991) Intensive Care Med, 17, pp. 149-153; Bergsneider, M., Hovda, D.A., Shalmon, E., Kelly, D.F., Vespa, P.M., Martin, N.A., Cerebral hyperglycolysis following severe traumatic brain injury in humans: A positron emission tomography study (1997) J Neurosurg, 86, pp. 241-251; Heiss, W.D., PET in coma and in vegetative state (2012) Eur J Neurol, 19, pp. 207-211; Laureys, S., Schiff, N.D., Coma and consciousness: Paradigms (re)framed by neuroimaging (2012) Neuroimage, 61, pp. 478-491; Stender, J., Gosseries, O., Bruno, M.A., Charland-Verville, V., Vanhaudenhuyse, A., Demertzi, A., Diagnostic precision of PET imaging and functional MRI in disorders of consciousness: A clinical validation study (2014) Lancet, 384, pp. 514-522; Laureys, S., Owen, A.M., Schiff, N.D., Brain function in coma, vegetative state, and related disorders (2004) Lancet Neurol, 3, pp. 537-546; Vanhaudenhuyse, A., Noirhomme, Q., Tshibanda, L.J., Bruno, M.A., Boveroux, P., Schnakers, C., Default network connectivity reflects the level of consciousness in non-communicative brain-damaged patients (2010) Brain, 133, pp. 161-171; Huang, Z., Dai, R., Wu, X., Yang, Z., Liu, D., Hu, J., The self and its resting state in consciousness: An investigation of the vegetative state (2014) Hum Brain Mapp, 35, pp. 1997-2008; Boly, M., Faymonville, M.E., Peigneux, P., Lambermont, B., Damas, P., Del Fiore, G., Auditory processing in severely brain injured patients: Differences between the minimally conscious state and the persistent vegetative state (2004) Arch Neurol, 61, pp. 233-238; Monti, M.M., Vanhaudenhuyse, A., Coleman, M.R., Boly, M., Pickard, J.D., Tshibanda, L., Willful modulation of brain activity in disorders of consciousness (2010) N Engl J Med, 362, pp. 579-589; Qin, P., Di, H., Liu, Y., Yu, S., Gong, Q., Duncan, N., Anterior cingulate activity and the self in disorders of consciousness (2010) Hum Brain Mapp, 31, pp. 1993-2002

PY - 2015

Y1 - 2015

KW - coma

KW - functional magnetic resonance imaging

KW - neural predispositions

KW - positron emission tomography

KW - 4 aminobutyric acid A receptor

KW - oxygen 15

KW - brain depth stimulation

KW - consciousness

KW - consciousness level

KW - correlational study

KW - disease predisposition

KW - electroencephalogram

KW - functional neuroimaging

KW - glucose metabolism

KW - human

KW - persistent vegetative state

KW - priority journal

KW - Review

KW - metabolism

KW - pathophysiology

KW - procedures

KW - Coma

KW - Functional Neuroimaging

KW - Humans

KW - Persistent Vegetative State

U2 - 10.1161/STROKEAHA.114.007969

DO - 10.1161/STROKEAHA.114.007969

M3 - Article

C2 - 25669313

VL - 46

SP - 1147

EP - 1151

JO - Stroke

JF - Stroke

SN - 0039-2499

IS - 4

ER -