White-light fluorescent nanoparticles from self-assembly of rhodamine B-anchored amphiphilic poly(poly(ethylene glycol)methacrylate)-b-poly(glycidyl methacrylate) block copolymer

Shih Chieh Chang, Shih Jiuan Chiu, Chih Yuan Hsu, Yung Chang, Ying Ling Liu

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Rhodamine B (RhB)-anchored amphiphilic poly(poly(ethylene glycol)methacrylate)-b-poly(glycidyl methacrylate) block copolymer (PPEGMA-b-PGMA/RhB) has been prepared by a sequential atom transfer radical polymerization and post-functionalization of RhB. The chemical structure of PPEGMA-b-PGMA/RhB is characterized with gel-permeation chromatography, Fourier-transform infrared spectroscopy, and 1H nuclear magnetic resonance spectroscopy. PPEGMA-b-PGMA/RhB has shown self-assembly behaviors in tetrahydrofuran and aqueous solutions. The RhB aggregation induced with the inter-molecular interaction of RhB results in the various core-shell structures of the assembled nanoparticles. The photoluminescent properties of the PPEGMA-b-PGMA/RhB nanoparticles are structure-dependent and exhibit yellow-light, blue-light, and white-light emissions. The fluorescent organic nanoparticles of PPEGMA-b-PGMA/RhB in aqueous solution show low cytotoxicity and have been used as a bio-dye for cell labelling. Internalization of PPEGMA-b-PGMA/RhB nanoparticles into HELA cells to exhibit fluorescent images has been demonstrated.

Original languageEnglish
Pages (from-to)4399-4406
Number of pages8
JournalPolymer
Volume53
Issue number20
DOIs
Publication statusPublished - Sep 12 2012

Fingerprint

rhodamine B
Self assembly
Polyethylene glycols
Block copolymers
Nanoparticles
Molecular interactions
Atom transfer radical polymerization
Light emission
Gel permeation chromatography
Cytotoxicity
Labeling
Nuclear magnetic resonance spectroscopy
Fourier transform infrared spectroscopy
Agglomeration
Dyes
polyglycidyl methacrylate
poly(poly(ethylene glycol)methacrylate)

Keywords

  • Amphiphilic polymer
  • Fluorescence
  • Self-assembly

ASJC Scopus subject areas

  • Organic Chemistry
  • Polymers and Plastics

Cite this

White-light fluorescent nanoparticles from self-assembly of rhodamine B-anchored amphiphilic poly(poly(ethylene glycol)methacrylate)-b-poly(glycidyl methacrylate) block copolymer. / Chang, Shih Chieh; Chiu, Shih Jiuan; Hsu, Chih Yuan; Chang, Yung; Liu, Ying Ling.

In: Polymer, Vol. 53, No. 20, 12.09.2012, p. 4399-4406.

Research output: Contribution to journalArticle

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abstract = "Rhodamine B (RhB)-anchored amphiphilic poly(poly(ethylene glycol)methacrylate)-b-poly(glycidyl methacrylate) block copolymer (PPEGMA-b-PGMA/RhB) has been prepared by a sequential atom transfer radical polymerization and post-functionalization of RhB. The chemical structure of PPEGMA-b-PGMA/RhB is characterized with gel-permeation chromatography, Fourier-transform infrared spectroscopy, and 1H nuclear magnetic resonance spectroscopy. PPEGMA-b-PGMA/RhB has shown self-assembly behaviors in tetrahydrofuran and aqueous solutions. The RhB aggregation induced with the inter-molecular interaction of RhB results in the various core-shell structures of the assembled nanoparticles. The photoluminescent properties of the PPEGMA-b-PGMA/RhB nanoparticles are structure-dependent and exhibit yellow-light, blue-light, and white-light emissions. The fluorescent organic nanoparticles of PPEGMA-b-PGMA/RhB in aqueous solution show low cytotoxicity and have been used as a bio-dye for cell labelling. Internalization of PPEGMA-b-PGMA/RhB nanoparticles into HELA cells to exhibit fluorescent images has been demonstrated.",
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