Wernicke's Encephalopathy: a case report

Shu-Chiang Hsieh, Chih Hsing Wu, Hsiu Chen Shih, Chia-Yuen Chen, Wing P. Chan

Research output: Contribution to conferencePaper

Abstract

BACKGROUND: Wernicke's encephalopathy is a potentially reversible disorder. The usual findings at MR imaging in
patients with Wernicke's encephalopathy include high signal intensities in the medial thalami and periaqueductal
regions of the midbrain. We describe a patient with acute Wernicke encephalopathy that showed a typical location of
hyperintense lesions on fluid-attenuated inversion recovery (FLAIR) and diffusion-weighted images.
CASE REPORT: A 78-year-old non-alcoholic woman was admitted to our department because of drowsiness, chest
pain and short of breath about 4~5 days. Head CT revealed only mild brain atrophy. On MR imaging, increased T2
signal of paraventricular regions of the thalamus and periaqueductal regions of the midbrain was observed. High-dose
thiamine therapy was started. The clinical condition improved gradually.
CONCLUSION: MR imaging is useful in early detecting and confirming the diagnosis of acute Wernicke's
encephalopathy when high-dose thiamine treatment can improve the prognosis of WE.
Original languageEnglish
Publication statusPublished - Mar 2009
EventTHE 58TH ANNUAL MEETING OF RSROC - Taichung Veterans General Hospital, Taichung , Taiwan
Duration: Mar 28 2009Mar 29 2009
https://www.rsroc.org.tw/annual/annualnews_detail.asp?id=6

Conference

ConferenceTHE 58TH ANNUAL MEETING OF RSROC
CountryTaiwan
CityTaichung
Period3/28/093/29/09
Internet address

Fingerprint

Wernicke Encephalopathy
Mesencephalon
Thalamus
Sleep Stages
Thiamine
Atrophy
Inpatients
Head
Brain
Therapeutics

Cite this

Hsieh, S-C., Wu, C. H., Shih, H. C., Chen, C-Y., & Chan, W. P. (2009). Wernicke's Encephalopathy: a case report. Paper presented at THE 58TH ANNUAL MEETING OF RSROC , Taichung , Taiwan.

Wernicke's Encephalopathy : a case report. / Hsieh, Shu-Chiang; Wu, Chih Hsing; Shih, Hsiu Chen; Chen, Chia-Yuen; Chan, Wing P.

2009. Paper presented at THE 58TH ANNUAL MEETING OF RSROC , Taichung , Taiwan.

Research output: Contribution to conferencePaper

Hsieh, S-C, Wu, CH, Shih, HC, Chen, C-Y & Chan, WP 2009, 'Wernicke's Encephalopathy: a case report' Paper presented at THE 58TH ANNUAL MEETING OF RSROC , Taichung , Taiwan, 3/28/09 - 3/29/09, .
Hsieh S-C, Wu CH, Shih HC, Chen C-Y, Chan WP. Wernicke's Encephalopathy: a case report. 2009. Paper presented at THE 58TH ANNUAL MEETING OF RSROC , Taichung , Taiwan.
Hsieh, Shu-Chiang ; Wu, Chih Hsing ; Shih, Hsiu Chen ; Chen, Chia-Yuen ; Chan, Wing P. / Wernicke's Encephalopathy : a case report. Paper presented at THE 58TH ANNUAL MEETING OF RSROC , Taichung , Taiwan.
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AU - Hsieh, Shu-Chiang

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AU - Chan, Wing P.

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N2 - BACKGROUND: Wernicke's encephalopathy is a potentially reversible disorder. The usual findings at MR imaging inpatients with Wernicke's encephalopathy include high signal intensities in the medial thalami and periaqueductalregions of the midbrain. We describe a patient with acute Wernicke encephalopathy that showed a typical location ofhyperintense lesions on fluid-attenuated inversion recovery (FLAIR) and diffusion-weighted images.CASE REPORT: A 78-year-old non-alcoholic woman was admitted to our department because of drowsiness, chestpain and short of breath about 4~5 days. Head CT revealed only mild brain atrophy. On MR imaging, increased T2signal of paraventricular regions of the thalamus and periaqueductal regions of the midbrain was observed. High-dosethiamine therapy was started. The clinical condition improved gradually.CONCLUSION: MR imaging is useful in early detecting and confirming the diagnosis of acute Wernicke'sencephalopathy when high-dose thiamine treatment can improve the prognosis of WE.

AB - BACKGROUND: Wernicke's encephalopathy is a potentially reversible disorder. The usual findings at MR imaging inpatients with Wernicke's encephalopathy include high signal intensities in the medial thalami and periaqueductalregions of the midbrain. We describe a patient with acute Wernicke encephalopathy that showed a typical location ofhyperintense lesions on fluid-attenuated inversion recovery (FLAIR) and diffusion-weighted images.CASE REPORT: A 78-year-old non-alcoholic woman was admitted to our department because of drowsiness, chestpain and short of breath about 4~5 days. Head CT revealed only mild brain atrophy. On MR imaging, increased T2signal of paraventricular regions of the thalamus and periaqueductal regions of the midbrain was observed. High-dosethiamine therapy was started. The clinical condition improved gradually.CONCLUSION: MR imaging is useful in early detecting and confirming the diagnosis of acute Wernicke'sencephalopathy when high-dose thiamine treatment can improve the prognosis of WE.

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