Wernicke's Encephalopathy: a case report

Shu-Chiang Hsieh, Chih Hsing Wu, Hsiu Chen Shih, Chia-Yuen Chen, Wing P. Chan

Research output: Contribution to conferencePaper


BACKGROUND: Wernicke's encephalopathy is a potentially reversible disorder. The usual findings at MR imaging in
patients with Wernicke's encephalopathy include high signal intensities in the medial thalami and periaqueductal
regions of the midbrain. We describe a patient with acute Wernicke encephalopathy that showed a typical location of
hyperintense lesions on fluid-attenuated inversion recovery (FLAIR) and diffusion-weighted images.
CASE REPORT: A 78-year-old non-alcoholic woman was admitted to our department because of drowsiness, chest
pain and short of breath about 4~5 days. Head CT revealed only mild brain atrophy. On MR imaging, increased T2
signal of paraventricular regions of the thalamus and periaqueductal regions of the midbrain was observed. High-dose
thiamine therapy was started. The clinical condition improved gradually.
CONCLUSION: MR imaging is useful in early detecting and confirming the diagnosis of acute Wernicke's
encephalopathy when high-dose thiamine treatment can improve the prognosis of WE.
Translated title of the contributionWernicke氏腦病變: 病例報告
Original languageEnglish
Publication statusPublished - Mar 2009
EventTHE 58TH ANNUAL MEETING OF RSROC - Taichung Veterans General Hospital, Taichung , Taiwan
Duration: Mar 28 2009Mar 29 2009


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    Hsieh, S-C., Wu, C. H., Shih, H. C., Chen, C-Y., & Chan, W. P. (2009). Wernicke's Encephalopathy: a case report. Paper presented at THE 58TH ANNUAL MEETING OF RSROC , Taichung , Taiwan. https://www.rsroc.org.tw/DB/AnnNews/file/6-3.pdf