Abstract

Objectives: Obesity is a pandemic health problem. Bariatric surgery is the only efficient method for long-term effective weight loss in subjects with severe obesity. Laparoscopic adjustable gastric banding (LAGB) has been widely applied for weight loss. However, a novel technique called laparoscopic adjustable gastric banded plication (LAGBP) has been proposed as an alternative to LAGB. Surgeons generally consider LAGBP to have a relative advantage on weight loss than that derived from LAGB. This initial study applied various biostatistical models and considered a relative longer observation period to compare the effects of LAGB and LAGBP. Methods: A total of 340 obese patients (290 who underwent LAGB and 50 who underwent LAGBP) with a body mass index of ≥35 kg/m2 and ages 20 to 55 y were recruited from the Division of General Surgery, Taipei Medical University Hospital in Taipei, Taiwan and observed for 24 to 36 mo postoperatively. Results: Both surgical procedures resulted in significant weight loss, amelioration of poor glucose metabolism, and decreased serum triacylglycerol levels. However, the trend analysis showed no significant differences between the postoperative effects of LAGB and LAGBP (P for trend = 0.21 for body mass index reduction, 0.13 for total body fat percentage reduction, 0.25–0.29 for glucose metabolism amelioration, and 0.10–0.29 for blood pressure improvement). Improvements in serum total cholesterol and high-density lipoprotein cholesterol levels were observed after LAGB only and LAGBP only, respectively, at 24 mo postoperatively. The Framingham Coronary Heart Disease Risk score also showed significant decrease for patients who underwent LAGB and LAGBP. Conclusions: Both LAGB and LAGBP demonstrated comparable efficacy in reducing body weight and improving metabolic parameters in a 24 to 36 mo follow-up period. LABG showed the ability to reduce systolic blood pressure and LAGBP exhibited triacylglycerol-lowering effects. A longer observational period is needed in future studies.

LanguageEnglish
Pages290-299
Number of pages10
JournalNutrition
Volume57
DOIs
Publication statusPublished - Jan 1 2019

Fingerprint

Weight Loss
Stomach
Blood Pressure
Triglycerides
Body Mass Index
Glucose
Bariatric Surgery
Morbid Obesity
Pandemics
Serum
Taiwan
HDL Cholesterol
Coronary Disease
Adipose Tissue

Keywords

  • Cholesterol
  • Glucose
  • Laparoscopic adjustable gastric banded plication
  • Laparoscopic adjustable gastric banding
  • Obesity
  • Triacylglycerol

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Nutrition and Dietetics

Cite this

Weight loss and metabolic improvements in obese patients undergoing gastric banding and gastric banded plication : A comparison. / Wang, Weu; Fann, Cathy S.J.; Yang, Shwu Huey; Chen, Hsin Hung; Chen, Chih Yen.

In: Nutrition, Vol. 57, 01.01.2019, p. 290-299.

Research output: Contribution to journalArticle

@article{f16d765f8285441d9ef3f0dd693db997,
title = "Weight loss and metabolic improvements in obese patients undergoing gastric banding and gastric banded plication: A comparison",
abstract = "Objectives: Obesity is a pandemic health problem. Bariatric surgery is the only efficient method for long-term effective weight loss in subjects with severe obesity. Laparoscopic adjustable gastric banding (LAGB) has been widely applied for weight loss. However, a novel technique called laparoscopic adjustable gastric banded plication (LAGBP) has been proposed as an alternative to LAGB. Surgeons generally consider LAGBP to have a relative advantage on weight loss than that derived from LAGB. This initial study applied various biostatistical models and considered a relative longer observation period to compare the effects of LAGB and LAGBP. Methods: A total of 340 obese patients (290 who underwent LAGB and 50 who underwent LAGBP) with a body mass index of ≥35 kg/m2 and ages 20 to 55 y were recruited from the Division of General Surgery, Taipei Medical University Hospital in Taipei, Taiwan and observed for 24 to 36 mo postoperatively. Results: Both surgical procedures resulted in significant weight loss, amelioration of poor glucose metabolism, and decreased serum triacylglycerol levels. However, the trend analysis showed no significant differences between the postoperative effects of LAGB and LAGBP (P for trend = 0.21 for body mass index reduction, 0.13 for total body fat percentage reduction, 0.25–0.29 for glucose metabolism amelioration, and 0.10–0.29 for blood pressure improvement). Improvements in serum total cholesterol and high-density lipoprotein cholesterol levels were observed after LAGB only and LAGBP only, respectively, at 24 mo postoperatively. The Framingham Coronary Heart Disease Risk score also showed significant decrease for patients who underwent LAGB and LAGBP. Conclusions: Both LAGB and LAGBP demonstrated comparable efficacy in reducing body weight and improving metabolic parameters in a 24 to 36 mo follow-up period. LABG showed the ability to reduce systolic blood pressure and LAGBP exhibited triacylglycerol-lowering effects. A longer observational period is needed in future studies.",
keywords = "Cholesterol, Glucose, Laparoscopic adjustable gastric banded plication, Laparoscopic adjustable gastric banding, Obesity, Triacylglycerol, Cholesterol, Glucose, Laparoscopic adjustable gastric banded plication, Laparoscopic adjustable gastric banding, Obesity, Triacylglycerol",
author = "Weu Wang and Fann, {Cathy S.J.} and Yang, {Shwu Huey} and Chen, {Hsin Hung} and Chen, {Chih Yen}",
year = "2019",
month = "1",
day = "1",
doi = "10.1016/j.nut.2018.05.024",
language = "English",
volume = "57",
pages = "290--299",
journal = "Nutrition",
issn = "0899-9007",
publisher = "Elsevier Inc.",

}

TY - JOUR

T1 - Weight loss and metabolic improvements in obese patients undergoing gastric banding and gastric banded plication

T2 - Nutrition

AU - Wang, Weu

AU - Fann, Cathy S.J.

AU - Yang, Shwu Huey

AU - Chen, Hsin Hung

AU - Chen, Chih Yen

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Objectives: Obesity is a pandemic health problem. Bariatric surgery is the only efficient method for long-term effective weight loss in subjects with severe obesity. Laparoscopic adjustable gastric banding (LAGB) has been widely applied for weight loss. However, a novel technique called laparoscopic adjustable gastric banded plication (LAGBP) has been proposed as an alternative to LAGB. Surgeons generally consider LAGBP to have a relative advantage on weight loss than that derived from LAGB. This initial study applied various biostatistical models and considered a relative longer observation period to compare the effects of LAGB and LAGBP. Methods: A total of 340 obese patients (290 who underwent LAGB and 50 who underwent LAGBP) with a body mass index of ≥35 kg/m2 and ages 20 to 55 y were recruited from the Division of General Surgery, Taipei Medical University Hospital in Taipei, Taiwan and observed for 24 to 36 mo postoperatively. Results: Both surgical procedures resulted in significant weight loss, amelioration of poor glucose metabolism, and decreased serum triacylglycerol levels. However, the trend analysis showed no significant differences between the postoperative effects of LAGB and LAGBP (P for trend = 0.21 for body mass index reduction, 0.13 for total body fat percentage reduction, 0.25–0.29 for glucose metabolism amelioration, and 0.10–0.29 for blood pressure improvement). Improvements in serum total cholesterol and high-density lipoprotein cholesterol levels were observed after LAGB only and LAGBP only, respectively, at 24 mo postoperatively. The Framingham Coronary Heart Disease Risk score also showed significant decrease for patients who underwent LAGB and LAGBP. Conclusions: Both LAGB and LAGBP demonstrated comparable efficacy in reducing body weight and improving metabolic parameters in a 24 to 36 mo follow-up period. LABG showed the ability to reduce systolic blood pressure and LAGBP exhibited triacylglycerol-lowering effects. A longer observational period is needed in future studies.

AB - Objectives: Obesity is a pandemic health problem. Bariatric surgery is the only efficient method for long-term effective weight loss in subjects with severe obesity. Laparoscopic adjustable gastric banding (LAGB) has been widely applied for weight loss. However, a novel technique called laparoscopic adjustable gastric banded plication (LAGBP) has been proposed as an alternative to LAGB. Surgeons generally consider LAGBP to have a relative advantage on weight loss than that derived from LAGB. This initial study applied various biostatistical models and considered a relative longer observation period to compare the effects of LAGB and LAGBP. Methods: A total of 340 obese patients (290 who underwent LAGB and 50 who underwent LAGBP) with a body mass index of ≥35 kg/m2 and ages 20 to 55 y were recruited from the Division of General Surgery, Taipei Medical University Hospital in Taipei, Taiwan and observed for 24 to 36 mo postoperatively. Results: Both surgical procedures resulted in significant weight loss, amelioration of poor glucose metabolism, and decreased serum triacylglycerol levels. However, the trend analysis showed no significant differences between the postoperative effects of LAGB and LAGBP (P for trend = 0.21 for body mass index reduction, 0.13 for total body fat percentage reduction, 0.25–0.29 for glucose metabolism amelioration, and 0.10–0.29 for blood pressure improvement). Improvements in serum total cholesterol and high-density lipoprotein cholesterol levels were observed after LAGB only and LAGBP only, respectively, at 24 mo postoperatively. The Framingham Coronary Heart Disease Risk score also showed significant decrease for patients who underwent LAGB and LAGBP. Conclusions: Both LAGB and LAGBP demonstrated comparable efficacy in reducing body weight and improving metabolic parameters in a 24 to 36 mo follow-up period. LABG showed the ability to reduce systolic blood pressure and LAGBP exhibited triacylglycerol-lowering effects. A longer observational period is needed in future studies.

KW - Cholesterol

KW - Glucose

KW - Laparoscopic adjustable gastric banded plication

KW - Laparoscopic adjustable gastric banding

KW - Obesity

KW - Triacylglycerol

KW - Cholesterol

KW - Glucose

KW - Laparoscopic adjustable gastric banded plication

KW - Laparoscopic adjustable gastric banding

KW - Obesity

KW - Triacylglycerol

UR - http://www.scopus.com/inward/record.url?scp=85053338218&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85053338218&partnerID=8YFLogxK

U2 - 10.1016/j.nut.2018.05.024

DO - 10.1016/j.nut.2018.05.024

M3 - Article

VL - 57

SP - 290

EP - 299

JO - Nutrition

JF - Nutrition

SN - 0899-9007

ER -