Warfarin-induced leukocytoclastic vasculitis

A case report and review of literature

Chien Yi Hsu, Wei Sheng Chen, Shih Hsien Sung

Research output: Contribution to journalReview article

13 Citations (Scopus)

Abstract

Warfarin is widely prescribed for patients with atrial fibrillation. In addition to unexpected bleeding, allergic skin reaction is one of its uncommon adverse effects. We herein report an 89-year-old man who, after taking warfarin for 4 years, suffered extensive skin eruptions. The skin biopsy disclosed leukocytoclastic vasculitis. The causal relationship between skin lesions and warfarin was confirmed after re-challenge of warfarin. A literature review revealed only 13 such cases reported from 1980 to 2011. Clinicians should be aware of this potential adverse effect of warfarin.

Original languageEnglish
Pages (from-to)601-606
Number of pages6
JournalInternal Medicine
Volume51
Issue number6
DOIs
Publication statusPublished - Mar 20 2012
Externally publishedYes

Fingerprint

Warfarin
Skin
Atrial Fibrillation
Hypersensitivity
Erythema elevatum diutinum
Hemorrhage
Biopsy

Keywords

  • Leukocytoclastic vasculitis
  • Warfarin

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Warfarin-induced leukocytoclastic vasculitis : A case report and review of literature. / Hsu, Chien Yi; Chen, Wei Sheng; Sung, Shih Hsien.

In: Internal Medicine, Vol. 51, No. 6, 20.03.2012, p. 601-606.

Research output: Contribution to journalReview article

Hsu, Chien Yi ; Chen, Wei Sheng ; Sung, Shih Hsien. / Warfarin-induced leukocytoclastic vasculitis : A case report and review of literature. In: Internal Medicine. 2012 ; Vol. 51, No. 6. pp. 601-606.
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