Vertebral Artery Hypoplasia is Associated With A Decrease in Net Vertebral Flow Volume

Yen Yu Chen, A. Ching Chao, Hung Yi Hsu, Chih Ping Chung, Han Hwa Hu

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

The definition and clinical significance of vertebral artery hypoplasia (VAH) remain inconclusive. VAH has been proposed as a predisposing factor of posterior circulation ischemic stroke. The aim of this study was to determine a best cut-off diameter of vertebral artery (VA) for VAH and to investigate if unilateral VAH is associated with a decrease in net vertebral flow volume. Retrospective data of 1000 presumably healthy subjects free of cerebrovascular disease or apparent carotid atherosclerosis were analysed. We found that a VA diameter ≤2.5 mm is an ideal value to define VAH. The flow volume of the identified hypoplastic VA was remarkably low and the contralateral VA had only a slightly increased compensatory flow volume. The net VA flow volumes remained significantly and markedly lower in subjects with unilateral VAH (140.7 ± 46.2 mL/min) than those in subjects without VAH (190.1 ± 54.5 mL/min, p < 0.001). Flow volume insufficiency of VA (defined as a net VA flow volume less than 100 mL/min) occurred more frequently in individuals with VAH than in those without VAH (22.1% vs. 2.4%, p < 0.001). Our study suggested that asymptomatic subjects with VAH had a significantly lower net VA flow volume and a higher frequency of VA flow insufficiency than the control group. (E-mail: hhhu@vghtpe.gov.tw).

Original languageEnglish
Pages (from-to)38-43
Number of pages6
JournalUltrasound in Medicine and Biology
Volume36
Issue number1
DOIs
Publication statusPublished - Jan 1 2010
Externally publishedYes

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Vertebral Artery
arteries
Vertebrobasilar Insufficiency
Cerebrovascular Disorders
Carotid Artery Diseases
arteriosclerosis

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Biophysics
  • Acoustics and Ultrasonics

Cite this

Vertebral Artery Hypoplasia is Associated With A Decrease in Net Vertebral Flow Volume. / Chen, Yen Yu; Chao, A. Ching; Hsu, Hung Yi; Chung, Chih Ping; Hu, Han Hwa.

In: Ultrasound in Medicine and Biology, Vol. 36, No. 1, 01.01.2010, p. 38-43.

Research output: Contribution to journalArticle

Chen, Yen Yu ; Chao, A. Ching ; Hsu, Hung Yi ; Chung, Chih Ping ; Hu, Han Hwa. / Vertebral Artery Hypoplasia is Associated With A Decrease in Net Vertebral Flow Volume. In: Ultrasound in Medicine and Biology. 2010 ; Vol. 36, No. 1. pp. 38-43.
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